David John
djhn87.bsky.social
David John
@djhn87.bsky.social
Bioinformatic & Data Scientist
Next Generation Sequencing, Single Cell and Spatial Biology, Machine Learning
Excited to share our newest work from the great @MarianoRuzJurado with great help from @StefanieDimmel1.

Together we implemented a neural networks and explainable AI that discovered new cardiac biomarkers and deepens our understanding of heart failure subtypes!
academic.oup.com/bib/article/...
November 14, 2025 at 9:32 AM
"Excited to share our new paper using #machine-learning to differentiate #heartfailure types and suggesting an improved way to detect important #marker-genes.
🚀 Grateful to all CoAuthors. Check it out here: www.biorxiv.org/content/10.1...
Decoding heart failure subtypes with neural networks via differential explanation analysis
Single-cell transcriptomics offers critical insights into the molecular mechanisms of heart failure with reduced or preserved ejection fraction. However, understanding these mechanisms is hindered by ...
www.biorxiv.org
March 14, 2025 at 6:57 AM
Reposted by David John
Decoding heart failure subtypes with neural networks via differential explanation analysis #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.1101/2025.03.03.641151v1
March 11, 2025 at 4:48 PM
Reposted by David John
A big day of output for the Human Cell Atlas, a global collaborative project with 100 countries to understand our ~37 trillion cells
A Wikipedia of our cells, a "remarkable achievement"
nature.com/articles/d41...
nature.com/immersive/d4...
November 20, 2024 at 5:04 PM