Darrell Downs, MD
djdownsmd.bsky.social
Darrell Downs, MD
@djdownsmd.bsky.social
Husband | Internal Medicine | Chief Resident | Interested in #MedEd | Aspiring Gastroenterologist
Reposted by Darrell Downs, MD
It's that time of the year again. In no particular order, I would like to share a few of #livertwitter in 2024 with #liversky

These could be original research, guidance statement, position paper or editorial. This is def not an inclusive list. Feel free to add to the 🧵
December 10, 2024 at 8:28 PM
Reposted by Darrell Downs, MD
C. jejuni promotes CRC metastasis through intratumor Campylobacter, whose production of genotoxin accelerates tumor metastasis

Strep bovis is a big dog in bacterial driving of CRC but don’t forget about Campylobacter!
cell.com/cell-host-micr…
December 6, 2024 at 12:50 PM
Reposted by Darrell Downs, MD
So you matched to GI…congratulations on being part of the #FutureOfGI! Now what’s next? 🤔

We have 3️⃣ resources to help you on the road 🛣️ to becoming a gastroenterologist. Bookmark this or share with someone who’s starting their journey in GI! ⤵️ #GastroSky #GIsky
December 4, 2024 at 8:00 PM
24+hrs later and it is still surreal. Thrilled to begin #GIFellowship at SUNY Downstate‼️

Special thanks to my family, friends and mentors for their unwavering support through this journey!

💩💩💩

#GastroSky #GISky

@asgeendo.bsky.social
@amergastroassn.bsky.social
@amcollegegastro.bsky.social
December 6, 2024 at 12:01 AM
Reposted by Darrell Downs, MD
Hepatorenal syndrome is a hemodynamic renal injury

Cirrhosis is a Precarious balance: driving with two feet

1. The gas pedal (output): gut pooling 🔽return; output preserved by catecholes
2. The tank: To🔼return, we🔼ADH,Aldo
3. The brakes: RAAS/catechole good till they aint
Empty tank▶️all brakes▶️HRS
November 29, 2024 at 1:23 PM
Reposted by Darrell Downs, MD
Me, lying down immediately after thanksgiving dinner: “alright gastroesophageal sphincter, your time to shine.”
November 28, 2024 at 11:25 PM
Reposted by Darrell Downs, MD
When I am doing ward rounds, I have a routine set of questions that I ask the patients. At first they sound like casual chatter but this is my version of system review! They cover everything and I can ask the same questions everyday. Try these & let me know if they work for you! #medsky #gastrosky
November 27, 2024 at 6:39 AM
Witching hour never disappoints #NFL
November 24, 2024 at 9:18 PM
This is awesome. Improving outcomes, one paracentesis at a time.

#LiverSky #GISky #MedSky
Need more fodder to motivate yourself or your colleagues to do that early diagnostic paracentesis?

New in @amcollegegastro.bsky.social #AJG, meta-analysis showing that diagnostic paracentesis within 12 hours improves mortality, shortens LOS and reduces AKI.

Link: journals.lww.com/ajg/pages/ar...
November 23, 2024 at 2:10 PM
Reposted by Darrell Downs, MD
It is critical for endocrinologists, PCPs to know how to "prescribe" exercise for MASLD prevention treatment.

Thankfully the awesome @jonathanstinemd.bsky.social will be talking about just this next Tues, 12/5 from 12-1p EST.

Link to register: register.gotowebinar.com/register/798...
November 20, 2024 at 5:59 PM
Reposted by Darrell Downs, MD
Everything you need to know about #cirrhosis in one picture?

Judge for yourself

pmc.ncbi.nlm.nih.gov/articles/PMC...
#medsky #liversky
November 12, 2024 at 12:21 AM
Reposted by Darrell Downs, MD
When your patient develops hepatic encephalopathy, give them Lactulose. It improves quality of life. And quantity!!!

But if the HE comes back rapidly, consider looking for and closing portosystemic shunts

Just ask this cat
November 19, 2024 at 12:57 AM
@bealoquebea.bsky.social is a must follow for all things IBD #MedSky #GastroSky #IBD
I know I'm a bit late, but here's the updated table of #IBD treatments with their doses & routes of administration with the addition of guselkumalb

Full quality table ➡️ www.ibd-eii.com/ibdcheatsheet/
November 17, 2024 at 5:53 PM
Reposted by Darrell Downs, MD
CAVALRY trial:
Open-label RCT of Child B/C cirrhosis pts with high risk varices.
- combination of carvedilol + banding reduces the risk of bleeding at 12 months
- reducing portal pressures + eradicating varices have additive effects without causing harm

#LiverSky #MedSky
November 17, 2024 at 4:26 AM
Reposted by Darrell Downs, MD
A nice overview of transplant allocation for HCC in 2024 #TLM24
November 16, 2024 at 5:14 PM
Fellowship rank list due soon! What better way to stem the anxiety of it all by seeing the what the #GIsky #Liversky #Medsky network is all about ‼️
November 15, 2024 at 10:31 PM