Dikic lab
@dikiclab.bsky.social
Research lab led by Ivan Dikic within IBC2, Goethe University Frankfurt.
Ubiquitination, autophagy, host-pathogen interactions
Ubiquitination, autophagy, host-pathogen interactions
Check out our latest paper: #Legionella SidE effectors phosphoribosyl-ubiquitinate SNAREs STX17 & SNAP29, stalling #autophagy and fueling bacterial growth. Dive into how pathogens hijack #ubiquitin driven autophagy @embojournal.org @ibc2-gu.bsky.social @idikic.bsky.social doi.org/10.1038/s443...
Phosphoribosyl ubiquitination of SNARE proteins regulates autophagy during Legionella infection | The EMBO Journal
imageimageAmong the hundreds of proteins that are secreted by Legionella pneumophila (the causative agent of Legionnaires’ disease) during infection, the SidE class of
effectors modify host proteins b...
doi.org
June 18, 2025 at 7:47 AM
Check out our latest paper: #Legionella SidE effectors phosphoribosyl-ubiquitinate SNAREs STX17 & SNAP29, stalling #autophagy and fueling bacterial growth. Dive into how pathogens hijack #ubiquitin driven autophagy @embojournal.org @ibc2-gu.bsky.social @idikic.bsky.social doi.org/10.1038/s443...
🏆 Congratulations to @adricovapinto.bsky.social for being awarded the @elife.bsky.social poster prize at the #FCQC2025 #autophagy #remodelling
@ibc2-gu.bsky.social
@ibc2-gu.bsky.social
March 27, 2025 at 12:44 PM
🏆 Congratulations to @adricovapinto.bsky.social for being awarded the @elife.bsky.social poster prize at the #FCQC2025 #autophagy #remodelling
@ibc2-gu.bsky.social
@ibc2-gu.bsky.social
Another day, another poster session 🪧 Come and chat with us tonight about ER-phagy, membrane remodelling, bacterial infection, #ubiquitin, #autophagy, and microproteins #FCQC2025 @ibc2-gu.bsky.social @idikic.bsky.social
Getting ready for day 3 of #FCQC2025! Excited to learn what is new in the fields of “Proteinopathies & neurodegeneration” and “Emerging therapeutics”.
@sfb1177.bsky.social @proxidrugs.bsky.social @ibc2-gu.bsky.social
@sfb1177.bsky.social @proxidrugs.bsky.social @ibc2-gu.bsky.social
March 26, 2025 at 2:05 PM
Another day, another poster session 🪧 Come and chat with us tonight about ER-phagy, membrane remodelling, bacterial infection, #ubiquitin, #autophagy, and microproteins #FCQC2025 @ibc2-gu.bsky.social @idikic.bsky.social
Reposted by Dikic lab
🤩 2nd day of #FCQC2025 conference in Frankfurt was filled with inspiring lectures, vibrant discussions, great posters and a lot of joy of meeting colleagues from all over the world! A huge thanks to all organizers & supporters!
@goetheuni.bsky.social @sfb1177.bsky.social @proxidrugs.bsky.social
@goetheuni.bsky.social @sfb1177.bsky.social @proxidrugs.bsky.social
March 26, 2025 at 8:23 AM
🤩 2nd day of #FCQC2025 conference in Frankfurt was filled with inspiring lectures, vibrant discussions, great posters and a lot of joy of meeting colleagues from all over the world! A huge thanks to all organizers & supporters!
@goetheuni.bsky.social @sfb1177.bsky.social @proxidrugs.bsky.social
@goetheuni.bsky.social @sfb1177.bsky.social @proxidrugs.bsky.social
Interested to hear about ribosomal frameshifting? Don't miss Audrey's presentation in the afternoon session (L23) 🎤
🪧 And come and talk to us at the poster session tonight. What topics? Many! molecular glues, bacterial infection, selective autophagy, ER-phagy, mass spec...
🪧 And come and talk to us at the poster session tonight. What topics? Many! molecular glues, bacterial infection, selective autophagy, ER-phagy, mass spec...
After an inspiring first day, we’re excited to dive into the second day of #FCQC2025 filled with amazing talks on „Organelles in biology and disease“ and „RNA and protein quality control“.
@sfb1177.bsky.social @proxidrugs.bsky.social @ibc2-gu.bsky.social
@sfb1177.bsky.social @proxidrugs.bsky.social @ibc2-gu.bsky.social
March 25, 2025 at 11:44 AM
Interested to hear about ribosomal frameshifting? Don't miss Audrey's presentation in the afternoon session (L23) 🎤
🪧 And come and talk to us at the poster session tonight. What topics? Many! molecular glues, bacterial infection, selective autophagy, ER-phagy, mass spec...
🪧 And come and talk to us at the poster session tonight. What topics? Many! molecular glues, bacterial infection, selective autophagy, ER-phagy, mass spec...
Reposted by Dikic lab
Great kick off of our #FCQC2025! Looking forward to the next days full of inspiring sessions, meaningful conversations, and exciting new connections 🙌
@sfb1177.bsky.social @enablefrankfurt.bsky.social @proxidrugs.bsky.social @goetheuni.bsky.social
@sfb1177.bsky.social @enablefrankfurt.bsky.social @proxidrugs.bsky.social @goetheuni.bsky.social
March 24, 2025 at 5:10 PM
Great kick off of our #FCQC2025! Looking forward to the next days full of inspiring sessions, meaningful conversations, and exciting new connections 🙌
@sfb1177.bsky.social @enablefrankfurt.bsky.social @proxidrugs.bsky.social @goetheuni.bsky.social
@sfb1177.bsky.social @enablefrankfurt.bsky.social @proxidrugs.bsky.social @goetheuni.bsky.social
What a timing! We just heard about this amazing story a moment ago at the #FCQC2025, and we can already dig further and read the paper! 😁 Congratulations, Leo and team! #ubiquitin #proteasome
Super excited to share our latest work on deciphering the #Ubiquitin Code
“𝗨𝗯𝗶𝗥𝗘𝗔𝗗 𝗱𝗲𝗰𝗶𝗽𝗵𝗲𝗿𝘀 𝗽𝗿𝗼𝘁𝗲𝗮𝘀𝗼𝗺𝗮𝗹 𝗱𝗲𝗴𝗿𝗮𝗱𝗮𝘁𝗶𝗼𝗻 𝗰𝗼𝗱𝗲 𝗼𝗳 𝗵𝗼𝗺𝗼𝘁𝘆𝗽𝗶𝗰 𝗮𝗻𝗱 𝗯𝗿𝗮𝗻𝗰𝗵𝗲𝗱 𝗞48 𝗮𝗻𝗱 𝗞63 𝘂𝗯𝗶𝗾𝘂𝗶𝘁𝗶𝗻 𝗰𝗵𝗮𝗶𝗻𝘀”
@cp-molcell.bsky.social
1/8
www.cell.com/molecular-ce...
“𝗨𝗯𝗶𝗥𝗘𝗔𝗗 𝗱𝗲𝗰𝗶𝗽𝗵𝗲𝗿𝘀 𝗽𝗿𝗼𝘁𝗲𝗮𝘀𝗼𝗺𝗮𝗹 𝗱𝗲𝗴𝗿𝗮𝗱𝗮𝘁𝗶𝗼𝗻 𝗰𝗼𝗱𝗲 𝗼𝗳 𝗵𝗼𝗺𝗼𝘁𝘆𝗽𝗶𝗰 𝗮𝗻𝗱 𝗯𝗿𝗮𝗻𝗰𝗵𝗲𝗱 𝗞48 𝗮𝗻𝗱 𝗞63 𝘂𝗯𝗶𝗾𝘂𝗶𝘁𝗶𝗻 𝗰𝗵𝗮𝗶𝗻𝘀”
@cp-molcell.bsky.social
1/8
www.cell.com/molecular-ce...
UbiREAD deciphers proteasomal degradation code of homotypic and branched K48 and K63 ubiquitin chains
Ubiquitin chains determine the fates of their modified proteins, including proteasomal
degradation. Kiss et al. present UbiREAD, a technology to monitor cellular degradation
and deubiquitination at hi...
www.cell.com
March 24, 2025 at 3:50 PM
What a timing! We just heard about this amazing story a moment ago at the #FCQC2025, and we can already dig further and read the paper! 😁 Congratulations, Leo and team! #ubiquitin #proteasome
Getting all set up for the conference!! We are looking forward to 4 days of exciting science 🤗 #FCQC25 #autophagy #proteostasis @ibc2-gu.bsky.social @sfb1177.bsky.social
March 24, 2025 at 8:39 AM
Getting all set up for the conference!! We are looking forward to 4 days of exciting science 🤗 #FCQC25 #autophagy #proteostasis @ibc2-gu.bsky.social @sfb1177.bsky.social
Last week at the 1st Symposium on Advances in Therapeutic Approaches, Uxía presented some of her PhD work. @uxiagestal.bsky.social @ibc2-gu.bsky.social @proxidrugs.bsky.social #EnableFrankfurt #BMBF #hmwk_hessen
Thanks to @doroteaartscience.bsky.social for the great illustration! #ScienceArt
Thanks to @doroteaartscience.bsky.social for the great illustration! #ScienceArt
December 9, 2024 at 11:11 AM
Last week at the 1st Symposium on Advances in Therapeutic Approaches, Uxía presented some of her PhD work. @uxiagestal.bsky.social @ibc2-gu.bsky.social @proxidrugs.bsky.social #EnableFrankfurt #BMBF #hmwk_hessen
Thanks to @doroteaartscience.bsky.social for the great illustration! #ScienceArt
Thanks to @doroteaartscience.bsky.social for the great illustration! #ScienceArt
Reposted by Dikic lab
🌟PhD positions at the IMPRS on Cellular Biophysics🌟 Applications are now open! 🎉
If you are looking for a #phdposition in the #lifesciences, take the chance and #apply for our program by Feb 7.
Submit your application through our website: 👉 imprs-cbp.mpg.de
#imprs_cbp #phd #gradschool #science
If you are looking for a #phdposition in the #lifesciences, take the chance and #apply for our program by Feb 7.
Submit your application through our website: 👉 imprs-cbp.mpg.de
#imprs_cbp #phd #gradschool #science
December 8, 2024 at 11:18 PM
🌟PhD positions at the IMPRS on Cellular Biophysics🌟 Applications are now open! 🎉
If you are looking for a #phdposition in the #lifesciences, take the chance and #apply for our program by Feb 7.
Submit your application through our website: 👉 imprs-cbp.mpg.de
#imprs_cbp #phd #gradschool #science
If you are looking for a #phdposition in the #lifesciences, take the chance and #apply for our program by Feb 7.
Submit your application through our website: 👉 imprs-cbp.mpg.de
#imprs_cbp #phd #gradschool #science
🥁 We are live on BlueSky!! Stay tuned for more news and updates from our lab. We are looking forward to connecting with you here again.
@ibc2-gu.bsky.social @idikic.bsky.social #GoetheUniversity #IBC2
@ibc2-gu.bsky.social @idikic.bsky.social #GoetheUniversity #IBC2
December 6, 2024 at 12:45 PM
🥁 We are live on BlueSky!! Stay tuned for more news and updates from our lab. We are looking forward to connecting with you here again.
@ibc2-gu.bsky.social @idikic.bsky.social #GoetheUniversity #IBC2
@ibc2-gu.bsky.social @idikic.bsky.social #GoetheUniversity #IBC2