Danfeng Cai
@danfengcai.bsky.social
Assistant Professor at Johns Hopkins School of Public Health studying biomolecular condensates, gene regulation, and cancer.
Pinned
Danfeng Cai
@danfengcai.bsky.social
· May 17
Rainbow Nucleus Charts Dynamic Interactome of Membrane-less Organelles by Danfeng Cai and team
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Our preprint is up!!
Reposted by Danfeng Cai
Check out a technology feature in @nature.com by Elie Dolgin regarding our recent 'Killswitch' publication
www.nature.com/articles/d41...
Thank you for the comments and first impressions by Rick Young, Isaac Klein, @danfengcai.bsky.social @superscijew.bsky.social
@yaotianzhang.bsky.social
www.nature.com/articles/d41...
Thank you for the comments and first impressions by Rick Young, Isaac Klein, @danfengcai.bsky.social @superscijew.bsky.social
@yaotianzhang.bsky.social
‘Killswitch’ protein lets scientists study immobilized cellular droplets
Synthetic peptide fixes biomolecular condensates, revealing how these enigmatic cell structures actually work.
www.nature.com
June 17, 2025 at 7:43 PM
Check out a technology feature in @nature.com by Elie Dolgin regarding our recent 'Killswitch' publication
www.nature.com/articles/d41...
Thank you for the comments and first impressions by Rick Young, Isaac Klein, @danfengcai.bsky.social @superscijew.bsky.social
@yaotianzhang.bsky.social
www.nature.com/articles/d41...
Thank you for the comments and first impressions by Rick Young, Isaac Klein, @danfengcai.bsky.social @superscijew.bsky.social
@yaotianzhang.bsky.social
Highlight on our recent work on TFE3 fusion translocation renal cell carcinoma
Translocation renal cell carcinoma (tRCC) is an aggressive cancer with no effective treatment. @danfengcai.bsky.social's Lab, working with the Toska Lab @hopkinsmedicine.bsky.social, found that 2 tRCC fusion oncoproteins alter transcription and drive tumor growth by forming biomolecular condensates.
BMB Research Highlights | Johns Hopkins Bloomberg School of Public Health
publichealth.jhu.edu
June 2, 2025 at 4:28 PM
Highlight on our recent work on TFE3 fusion translocation renal cell carcinoma
Our preprint is up!!
Rainbow Nucleus Charts Dynamic Interactome of Membrane-less Organelles by Danfeng Cai and team
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
May 17, 2025 at 12:52 AM
Our preprint is up!!
So happy our paper on TFE3 fusion oncoprotein condensates in translocation RCC is online at Cell Reports! Great collaboration from Eneda Toska, Vito Rebecca, Marston Linehan and Hongkai Ji labs. Proud of the work of trainees Choon Leng So, Jane Lee, Bujamin Vokshi et al www.cell.com/cell-reports...
TFE3 fusion oncoprotein condensates drive transcriptional reprogramming and cancer progression in translocation renal cell carcinoma
So et al. investigate TFE3 fusion oncoproteins (FOs) in translocation renal cell carcinoma
(tRCC) and find that TFE3 FOs form transcriptional condensates and drive tRCC progression.
The structured coi...
www.cell.com
April 16, 2025 at 2:23 PM
So happy our paper on TFE3 fusion oncoprotein condensates in translocation RCC is online at Cell Reports! Great collaboration from Eneda Toska, Vito Rebecca, Marston Linehan and Hongkai Ji labs. Proud of the work of trainees Choon Leng So, Jane Lee, Bujamin Vokshi et al www.cell.com/cell-reports...
Ending the week with paper acceptance. Congratulations Jane and Choon!! (A dramatic champange opening moment)
March 21, 2025 at 3:10 PM
Ending the week with paper acceptance. Congratulations Jane and Choon!! (A dramatic champange opening moment)