Cristian Topriceanu, MD
@ctopriceanu.bsky.social
Innovating for CV health🫀
Cardiology Fellow @RoyalFreeNHS
Research Fellow @UCL_ICS #CVimaging, #PopulationScience, #Multiomics
Cardiology Fellow @RoyalFreeNHS
Research Fellow @UCL_ICS #CVimaging, #PopulationScience, #Multiomics
It was a pleasure to present in the Melvin Judkins Early Career Clinical Investigator Award session at #AHA25 (hosted by @americanheart.bsky.social) and to serve as a #SoMe ambassador for @accintouch.bsky.social and @jaccjournals.bsky.social!
Proud to have represented @uclpophealthsci.bsky.social!
Proud to have represented @uclpophealthsci.bsky.social!
November 11, 2025 at 2:19 AM
It was a pleasure to present in the Melvin Judkins Early Career Clinical Investigator Award session at #AHA25 (hosted by @americanheart.bsky.social) and to serve as a #SoMe ambassador for @accintouch.bsky.social and @jaccjournals.bsky.social!
Proud to have represented @uclpophealthsci.bsky.social!
Proud to have represented @uclpophealthsci.bsky.social!
🚨 #AHA2025- CorCMR study: In patients with chest pain + non-obstructive coronary arteries, stress #whyCMR diagnosed microvascular angina in 50% vs <1% with angiogram alone. QoL improved 22 vs <1 point at 1 year.
Read more: shorturl.at/JymI9
@accintouch.bsky.social @jaccjournals.bsky.social
Read more: shorturl.at/JymI9
@accintouch.bsky.social @jaccjournals.bsky.social
CorCMR: Stress CMR Imaging May Help Improve Diagnosis and Treatment of Angina - American College of Cardiology
shorturl.at
November 10, 2025 at 6:23 PM
🚨 #AHA2025- CorCMR study: In patients with chest pain + non-obstructive coronary arteries, stress #whyCMR diagnosed microvascular angina in 50% vs <1% with angiogram alone. QoL improved 22 vs <1 point at 1 year.
Read more: shorturl.at/JymI9
@accintouch.bsky.social @jaccjournals.bsky.social
Read more: shorturl.at/JymI9
@accintouch.bsky.social @jaccjournals.bsky.social
Reposted by Cristian Topriceanu, MD
#AHA25: With ⬆️ BP continuing to be a 🌍 challenge, effective management must remain a global priority. The results from BETTER-BP 👇, GOFRESH & Healthy Family offer 3 strategies targeting behavior, diet & family that could inform larger-scale programs.
🔗 https://bit.ly/3XiMhr0 #CardioSky #MedSky
🔗 https://bit.ly/3XiMhr0 #CardioSky #MedSky
November 9, 2025 at 10:45 PM
#AHA25: With ⬆️ BP continuing to be a 🌍 challenge, effective management must remain a global priority. The results from BETTER-BP 👇, GOFRESH & Healthy Family offer 3 strategies targeting behavior, diet & family that could inform larger-scale programs.
🔗 https://bit.ly/3XiMhr0 #CardioSky #MedSky
🔗 https://bit.ly/3XiMhr0 #CardioSky #MedSky
#AHA25: Mixed results for post-#Afib ablation care
❌ DARE-AF: dapagliflozin didn’t ⬇️ early #Afib recurrence.
✅ META-AF: Metformin ⬇️ recurrent #Afib in obese, non-diabetic pts at 1 yr.
💡 GLP-1 agonists next?
Full story: shorturl.at/SeCFP
@accintouch.bsky.social @jaccjournals.bsky.social
❌ DARE-AF: dapagliflozin didn’t ⬇️ early #Afib recurrence.
✅ META-AF: Metformin ⬇️ recurrent #Afib in obese, non-diabetic pts at 1 yr.
💡 GLP-1 agonists next?
Full story: shorturl.at/SeCFP
@accintouch.bsky.social @jaccjournals.bsky.social
DARE-AF and META-AF: Mixed Outcomes For Drug Strategies Following AFib Ablation - American College of Cardiology
shorturl.at
November 9, 2025 at 10:04 PM
#AHA25: Mixed results for post-#Afib ablation care
❌ DARE-AF: dapagliflozin didn’t ⬇️ early #Afib recurrence.
✅ META-AF: Metformin ⬇️ recurrent #Afib in obese, non-diabetic pts at 1 yr.
💡 GLP-1 agonists next?
Full story: shorturl.at/SeCFP
@accintouch.bsky.social @jaccjournals.bsky.social
❌ DARE-AF: dapagliflozin didn’t ⬇️ early #Afib recurrence.
✅ META-AF: Metformin ⬇️ recurrent #Afib in obese, non-diabetic pts at 1 yr.
💡 GLP-1 agonists next?
Full story: shorturl.at/SeCFP
@accintouch.bsky.social @jaccjournals.bsky.social
ANSWER-HF at #AHA25: RCT of sacubitril-valsartan vs enalapril in Chagas HF (n=190, 6-mo). LVEF ↑ 2.1% vs 1.2% (NS). NT-proBNP ↓32% vs enalapril (p<0.001). Win ratio 1.80 favors sac/val.
Read more: bit.ly/43mv5oh!
@jaccjournals.bsky.social @accintouch.bsky.social
Read more: bit.ly/43mv5oh!
@jaccjournals.bsky.social @accintouch.bsky.social
Sacubitril-Valsartan Versus Enalapril in Heart Failure Due to Chagas Disease: Primary Results of ANSWER-HF Randomized Trial:
View all available purchase options and get full access to this article.
bit.ly
November 9, 2025 at 9:49 PM
ANSWER-HF at #AHA25: RCT of sacubitril-valsartan vs enalapril in Chagas HF (n=190, 6-mo). LVEF ↑ 2.1% vs 1.2% (NS). NT-proBNP ↓32% vs enalapril (p<0.001). Win ratio 1.80 favors sac/val.
Read more: bit.ly/43mv5oh!
@jaccjournals.bsky.social @accintouch.bsky.social
Read more: bit.ly/43mv5oh!
@jaccjournals.bsky.social @accintouch.bsky.social
Reposted by Cristian Topriceanu, MD
Hear insights from #ACCPresident Christopher M. Kramer, MD, FACC, on the groundbreaking CRISPR-Cas9 trial presented at #AHA25 and what it means for cardiovascular care.
Get full details ➡️ https://bit.ly/47Nfb7O #CardioSky #MedSky #ACCAnywhere @chriskramermd.bsky.social
Get full details ➡️ https://bit.ly/47Nfb7O #CardioSky #MedSky #ACCAnywhere @chriskramermd.bsky.social
November 9, 2025 at 6:59 PM
Hear insights from #ACCPresident Christopher M. Kramer, MD, FACC, on the groundbreaking CRISPR-Cas9 trial presented at #AHA25 and what it means for cardiovascular care.
Get full details ➡️ https://bit.ly/47Nfb7O #CardioSky #MedSky #ACCAnywhere @chriskramermd.bsky.social
Get full details ➡️ https://bit.ly/47Nfb7O #CardioSky #MedSky #ACCAnywhere @chriskramermd.bsky.social
#AHA25 AFib shake-up 🫀⚡
OCEAN: post-ablation, rivaroxaban ↑ bleed, no stroke win vs aspirin → stop OAC ok.
ADAPT/OPTIMA: post-stent, NOAC alone or 1-mo DAPT wins.
CLOSURE: meds > LAAC in high-risk.
Read more: shorturl.at/jVkk1
@jaccjournals.bsky.social @accintouch.bsky.social
OCEAN: post-ablation, rivaroxaban ↑ bleed, no stroke win vs aspirin → stop OAC ok.
ADAPT/OPTIMA: post-stent, NOAC alone or 1-mo DAPT wins.
CLOSURE: meds > LAAC in high-risk.
Read more: shorturl.at/jVkk1
@jaccjournals.bsky.social @accintouch.bsky.social
New Trials Redefine Antithrombotic and Stroke Prevention Strategies in AFib - American College of Cardiology
shorturl.at
November 9, 2025 at 6:49 PM
#AHA25 AFib shake-up 🫀⚡
OCEAN: post-ablation, rivaroxaban ↑ bleed, no stroke win vs aspirin → stop OAC ok.
ADAPT/OPTIMA: post-stent, NOAC alone or 1-mo DAPT wins.
CLOSURE: meds > LAAC in high-risk.
Read more: shorturl.at/jVkk1
@jaccjournals.bsky.social @accintouch.bsky.social
OCEAN: post-ablation, rivaroxaban ↑ bleed, no stroke win vs aspirin → stop OAC ok.
ADAPT/OPTIMA: post-stent, NOAC alone or 1-mo DAPT wins.
CLOSURE: meds > LAAC in high-risk.
Read more: shorturl.at/jVkk1
@jaccjournals.bsky.social @accintouch.bsky.social
🚨New at #AHA25 & in #JACC: In the MAPLE-HCM trial, those with obstructive #HCM treated with aficamten showed superior improvements vs. metoprolol in:
🫀HF symptoms
💪 Exercise capacity
⚡LVOT gradient
💬 Health status
Read more: tinyurl.com/yez2ybss
@accintouch.bsky.social @jaccjournals.bsky.social
🫀HF symptoms
💪 Exercise capacity
⚡LVOT gradient
💬 Health status
Read more: tinyurl.com/yez2ybss
@accintouch.bsky.social @jaccjournals.bsky.social
Aficamten in Obstructive Hypertrophic Cardiomyopathy: A Multi-Domain, Patient-Level Analysis of the MAPLE-HCM Trial:
www.jacc.org
November 8, 2025 at 8:52 PM
🚨New at #AHA25 & in #JACC: In the MAPLE-HCM trial, those with obstructive #HCM treated with aficamten showed superior improvements vs. metoprolol in:
🫀HF symptoms
💪 Exercise capacity
⚡LVOT gradient
💬 Health status
Read more: tinyurl.com/yez2ybss
@accintouch.bsky.social @jaccjournals.bsky.social
🫀HF symptoms
💪 Exercise capacity
⚡LVOT gradient
💬 Health status
Read more: tinyurl.com/yez2ybss
@accintouch.bsky.social @jaccjournals.bsky.social
#VESALIUSCV at #AHA25: In >12,000 high-risk pts w/o prior MI or stroke, evolocumab cut risk of CHD death, MI, or ischemic stroke (HR ~0.75) & 4-pt MACE (HR ~0.81) over ~4.5 yrs. LDL-C ↓ ~55% to ~45 mg/dL.
Read more: shorturl.at/0LsXi
@accintouch.bsky.social @jaccjournals.bsky.social
Read more: shorturl.at/0LsXi
@accintouch.bsky.social @jaccjournals.bsky.social
VESALIUS-CV: Evolocumab vs. Placebo in Patients Without Previous MI or Stroke - American College of Cardiology
shorturl.at
November 8, 2025 at 8:26 PM
#VESALIUSCV at #AHA25: In >12,000 high-risk pts w/o prior MI or stroke, evolocumab cut risk of CHD death, MI, or ischemic stroke (HR ~0.75) & 4-pt MACE (HR ~0.81) over ~4.5 yrs. LDL-C ↓ ~55% to ~45 mg/dL.
Read more: shorturl.at/0LsXi
@accintouch.bsky.social @jaccjournals.bsky.social
Read more: shorturl.at/0LsXi
@accintouch.bsky.social @jaccjournals.bsky.social
First-in-human #CRISPR trial at #AHA25 🚀 One-time infusion targeting ANGPTL3 was safe and lowered both LDL-C & triglycerides.
🧬 Read more: bit.ly/47Nfb7O
@accintouch.bsky.social @jaccjournals.bsky.social
🧬 Read more: bit.ly/47Nfb7O
@accintouch.bsky.social @jaccjournals.bsky.social
First-in-Human Trial Suggests CRISPR-Cas9 Therapy Targeting ANGPTL3 is Safe and Reduces LDL and Triglycerides - American College of Cardiology
bit.ly
November 8, 2025 at 8:19 PM
First-in-human #CRISPR trial at #AHA25 🚀 One-time infusion targeting ANGPTL3 was safe and lowered both LDL-C & triglycerides.
🧬 Read more: bit.ly/47Nfb7O
@accintouch.bsky.social @jaccjournals.bsky.social
🧬 Read more: bit.ly/47Nfb7O
@accintouch.bsky.social @jaccjournals.bsky.social
Reposted by Cristian Topriceanu, MD
🆕 #JACC Leadership Page from #ACCPresident @chriskramermd.bsky.social and ACC leaders Drs. Malissa J. Wood and Sandra J. Lewis emphasize the value of intentional investment in leadership development ➕ non-clinical competencies.
Read more🔗 https://bit.ly/4hRRn7e #ACCLeadership #CardioSky #MedSky
Read more🔗 https://bit.ly/4hRRn7e #ACCLeadership #CardioSky #MedSky
November 7, 2025 at 10:00 PM
🆕 #JACC Leadership Page from #ACCPresident @chriskramermd.bsky.social and ACC leaders Drs. Malissa J. Wood and Sandra J. Lewis emphasize the value of intentional investment in leadership development ➕ non-clinical competencies.
Read more🔗 https://bit.ly/4hRRn7e #ACCLeadership #CardioSky #MedSky
Read more🔗 https://bit.ly/4hRRn7e #ACCLeadership #CardioSky #MedSky
#AHA25 starts today! As a JACC Social Media Ambassador, I'll be posting live updates and key takeaways.
@accintouch.bsky.social
@jaccjournals.bsky.social
@accintouch.bsky.social
@jaccjournals.bsky.social
JACC Journals (@jaccjournals.bsky.social)
Official account representing the ACC's 10 #JACCJournals 📚, one of the most widely read and most impactful CV journal programs in the world 🫀 | https://www.jacc.org/
jaccjournals.bsky.social
November 7, 2025 at 4:29 PM
#AHA25 starts today! As a JACC Social Media Ambassador, I'll be posting live updates and key takeaways.
@accintouch.bsky.social
@jaccjournals.bsky.social
@accintouch.bsky.social
@jaccjournals.bsky.social
Reposted by Cristian Topriceanu, MD
Magnetic resonance imaging (MRI) scans of the heart could help to detect lamin heart disease earlier and enable clinicians to better predict which patients are most at risk, finds a new study led by Dr Cristian Topriceanu @ctopriceanu.bsky.social and Dr Gaby Captur @uclpophealthsci.bsky.social
MRI scans could help detect life-threatening heart disease
Magnetic resonance imaging (MRI) scans of the heart could help to detect a life-threatening heart disease and enable clinicians to better predict which patients are most at risk, according to a new st...
www.ucl.ac.uk
May 15, 2025 at 3:35 PM
Magnetic resonance imaging (MRI) scans of the heart could help to detect lamin heart disease earlier and enable clinicians to better predict which patients are most at risk, finds a new study led by Dr Cristian Topriceanu @ctopriceanu.bsky.social and Dr Gaby Captur @uclpophealthsci.bsky.social
Reposted by Cristian Topriceanu, MD
Magnetic resonance imaging (MRI) scans of the heart could help to detect lamin heart disease earlier and enable clinicians to better predict which patients are most at risk, finds a new study led by Dr Cristian Topriceanu @ctopriceanu.bsky.social and Dr Gaby Captur
MRI scans could help detect life-threatening heart disease
Magnetic resonance imaging (MRI) scans of the heart could help to detect a life-threatening heart disease and enable clinicians to better predict which patients are most at risk, according to a new…
www.ucl.ac.uk
June 3, 2025 at 3:42 PM
Magnetic resonance imaging (MRI) scans of the heart could help to detect lamin heart disease earlier and enable clinicians to better predict which patients are most at risk, finds a new study led by Dr Cristian Topriceanu @ctopriceanu.bsky.social and Dr Gaby Captur
✈️ Is aircraft noise bad for your heart?🫀
Exposure to higher aircraft noise is linked to adverse heart changes by #WhyCMR, potentially increasing the risk of #MACE.
Full paper @jaccjournals.bsky.social: tinyurl.com/5yx7j49b
@uclpophealthsci.bsky.social
Exposure to higher aircraft noise is linked to adverse heart changes by #WhyCMR, potentially increasing the risk of #MACE.
Full paper @jaccjournals.bsky.social: tinyurl.com/5yx7j49b
@uclpophealthsci.bsky.social
Redirecting
tinyurl.com
January 14, 2025 at 11:15 AM
✈️ Is aircraft noise bad for your heart?🫀
Exposure to higher aircraft noise is linked to adverse heart changes by #WhyCMR, potentially increasing the risk of #MACE.
Full paper @jaccjournals.bsky.social: tinyurl.com/5yx7j49b
@uclpophealthsci.bsky.social
Exposure to higher aircraft noise is linked to adverse heart changes by #WhyCMR, potentially increasing the risk of #MACE.
Full paper @jaccjournals.bsky.social: tinyurl.com/5yx7j49b
@uclpophealthsci.bsky.social