Cravedi Lab
@cravedilab.bsky.social
Kidney & Immunology Research at Icahn School of Medicine at Mount Sinai
Combined Anti-CD20/Anti-CD38 Therapy in Posttransplant Focal Segmental Glomerulosclerosis Recurrence: A Retrospective, International, Multicenter Study
journals.lww.com/transplantat...
journals.lww.com/transplantat...
journals.lww.com
January 22, 2026 at 3:30 PM
Combined Anti-CD20/Anti-CD38 Therapy in Posttransplant Focal Segmental Glomerulosclerosis Recurrence: A Retrospective, International, Multicenter Study
journals.lww.com/transplantat...
journals.lww.com/transplantat...
Final funding bill for NIH pushes back against Trump cuts | Science | AAAS www.science.org/content/arti...
Final funding bill for NIH pushes back against Trump cuts
Measure gives agency slight boost and blocks multiyear awards and cuts to indirect costs
www.science.org
January 20, 2026 at 8:09 PM
Final funding bill for NIH pushes back against Trump cuts | Science | AAAS www.science.org/content/arti...
B Cell Depletion in Glomerular Diseases: Not Always as Safe as We May Think - Kidney Medicine
www.kidneymedicinejournal.org/article/S259...
www.kidneymedicinejournal.org/article/S259...
B Cell Depletion in Glomerular Diseases: Not Always as Safe as We May Think
B cell depletion with chimeric anti-CD20 monoclonal antibody rituximab has revolutionized
the treatment of glomerular diseases. Obinutuzumab, a type II glycoengineered anti-CD20
humanized monoclonal a...
www.kidneymedicinejournal.org
January 15, 2026 at 1:53 PM
B Cell Depletion in Glomerular Diseases: Not Always as Safe as We May Think - Kidney Medicine
www.kidneymedicinejournal.org/article/S259...
www.kidneymedicinejournal.org/article/S259...
Chronic kidney disease - The Lancet www.thelancet.com/journals/lan...
Chronic kidney disease
Globally, the prevalence of chronic kidney disease is estimated to be approximately
850 million cases, with approximately 4 million individuals needing kidney replacement
therapy for kidney failure. B...
www.thelancet.com
January 3, 2026 at 12:07 PM
Chronic kidney disease - The Lancet www.thelancet.com/journals/lan...
Topography of the HLA-A protein enforces shared and convergent immunodominant B cell and antibody alloresponses in transplant recipients: Immunity www.cell.com/immunity/ful...
Topography of the HLA-A protein enforces shared and convergent immunodominant B cell and antibody alloresponses in transplant recipients
Donor-specific antibodies against mismatched HLA proteins cause allograft failure,
but the structural epitopes recognized by these antibodies are not well defined. Killian
et al. identify immunodomina...
www.cell.com
January 2, 2026 at 4:57 PM
Topography of the HLA-A protein enforces shared and convergent immunodominant B cell and antibody alloresponses in transplant recipients: Immunity www.cell.com/immunity/ful...
Reposted by Cravedi Lab
After eight years of training, Dr. Maureen McKiernan had 90 minutes to get a beating heart inside a 6-month-old infant. It was her first heart transplant as the lead surgeon and her first ever in an infant. Here's a look at the steps in the milestone operation.
90 Minutes to Give Baby Luna a New Heart
After eight years of training, Dr. Maureen McKiernan made her debut as the lead surgeon on an infant heart transplant — an operation on the edge of what’s possible.
nyti.ms
January 1, 2026 at 6:50 PM
After eight years of training, Dr. Maureen McKiernan had 90 minutes to get a beating heart inside a 6-month-old infant. It was her first heart transplant as the lead surgeon and her first ever in an infant. Here's a look at the steps in the milestone operation.
Reposted by Cravedi Lab
With all the excitement about AI giving us answers, we often forget that the real trick is to figure out what is the question.
December 29, 2025 at 5:02 PM
With all the excitement about AI giving us answers, we often forget that the real trick is to figure out what is the question.
Promoting Equity in Transplant Research by Addressing the Exclusion of Patients With Glomerular Disease -
Kidney International Reports www.kireports.org/article/S246...
Kidney International Reports www.kireports.org/article/S246...
Promoting Equity in Transplant Research by Addressing the Exclusion of Patients With Glomerular Disease
Kidney transplantation remains the treatment of choice for patients with end-stage
kidney disease (ESKD), offering superior survival and quality of life compared with
dialysis.1 Despite improvements i...
www.kireports.org
December 23, 2025 at 9:41 AM
Promoting Equity in Transplant Research by Addressing the Exclusion of Patients With Glomerular Disease -
Kidney International Reports www.kireports.org/article/S246...
Kidney International Reports www.kireports.org/article/S246...
Reposted by Cravedi Lab
When your PI presents your work
December 15, 2025 at 12:00 PM
When your PI presents your work
Reaching maturity: Thymic γδ T cell differentiation in mice and humans | Science Immunology www.science.org/doi/10.1126/...
Reaching maturity: Thymic γδ T cell differentiation in mice and humans
γδ T cell differentiation into specialized effector subsets during both early life and adulthood is reviewed.
www.science.org
December 15, 2025 at 12:55 AM
Reaching maturity: Thymic γδ T cell differentiation in mice and humans | Science Immunology www.science.org/doi/10.1126/...
Short-term glyco-editing during machine perfusion permits ABO-incompatible transplantation in a human decedent model
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Short-term glyco-editing during machine perfusion permits ABO-incompatible transplantation in a human decedent model
www.sciencedirect.com
December 12, 2025 at 9:25 PM
Short-term glyco-editing during machine perfusion permits ABO-incompatible transplantation in a human decedent model
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Increased Treg in Kidney Transplant Recipients With Erythrocytosis
www.frontierspartnerships.org/journals/tra...
www.frontierspartnerships.org/journals/tra...
Frontiers Publishing Partnerships | Increased Treg in Kidney Transplant Recipients With Erythrocytosis
Dear Editors, Erythropoietin (EPO) is a glycoprotein hormone produced predominantly by the kidney in response to hypoxia. While widely known for its hematopo...
www.frontierspartnerships.org
December 12, 2025 at 2:25 AM
Increased Treg in Kidney Transplant Recipients With Erythrocytosis
www.frontierspartnerships.org/journals/tra...
www.frontierspartnerships.org/journals/tra...
Reposted by Cravedi Lab
Preprint: CD19-directed CAR-T-cell therapy can induce rapid, durable remission of severe, refractory cold-agglutinin AIHA and simultaneously improve coexisting APLAS and ITP on a favorable toxicity profile
papers.ssrn.com/sol3/papers....
papers.ssrn.com/sol3/papers....
CD19 CAR-T-Cell Therapy in Refractory Autoimmune Hemolytic Anemia (AIHA) With Concurrent Immune Thrombocytopenia (ITP) and Antiphospholipid Antibody Syndrome (APLAS)
Background: Autoimmune hemolytic anemia (AIHA), immune thrombocytopenia (ITP), and antiphospholipid antibody syndrome (APLAS) are B-cell–driven autoimmune
papers.ssrn.com
December 5, 2025 at 1:12 AM
Preprint: CD19-directed CAR-T-cell therapy can induce rapid, durable remission of severe, refractory cold-agglutinin AIHA and simultaneously improve coexisting APLAS and ITP on a favorable toxicity profile
papers.ssrn.com/sol3/papers....
papers.ssrn.com/sol3/papers....
Reposted by Cravedi Lab
📢 SIGN & SHARE THE PETITION! 📢
New York needs an Empire Biomedical Research Institute to create new statewide funding opportunities for scientists & physician-scientists so that patients and their families get the life-saving and life-changing new therapeutics they're hoping for ✏️ c.org/TDMy2H9JTW
New York needs an Empire Biomedical Research Institute to create new statewide funding opportunities for scientists & physician-scientists so that patients and their families get the life-saving and life-changing new therapeutics they're hoping for ✏️ c.org/TDMy2H9JTW
Sign the Petition
Support a New York State Biomedical Institute for a Healthier, More Affordable Future
c.org
November 24, 2025 at 3:53 PM
📢 SIGN & SHARE THE PETITION! 📢
New York needs an Empire Biomedical Research Institute to create new statewide funding opportunities for scientists & physician-scientists so that patients and their families get the life-saving and life-changing new therapeutics they're hoping for ✏️ c.org/TDMy2H9JTW
New York needs an Empire Biomedical Research Institute to create new statewide funding opportunities for scientists & physician-scientists so that patients and their families get the life-saving and life-changing new therapeutics they're hoping for ✏️ c.org/TDMy2H9JTW
Kidney transplantation across ABO-H incompatibility in a recipient with Bombay blood group: A novel report - American Journal of Transplantation www.amjtransplant.org/article/S160...
Kidney transplantation across ABO-H incompatibility in a recipient with Bombay blood group: A novel report
The Bombay blood group is an exceptionally rare phenotype characterized by the absence
of H antigen on red blood cells due to mutations in the FUT1 gene and absence of H
substance in secretions from c...
www.amjtransplant.org
November 26, 2025 at 9:14 PM
Kidney transplantation across ABO-H incompatibility in a recipient with Bombay blood group: A novel report - American Journal of Transplantation www.amjtransplant.org/article/S160...
Increased Treg in Kidney Transplant Recipients With Erythrocytosis
www.frontierspartnerships.org/journals/tra...
www.frontierspartnerships.org/journals/tra...
Frontiers Publishing Partnerships | Increased Treg in Kidney Transplant Recipients With Erythrocytosis
Dear Editors, Erythropoietin (EPO) is a glycoprotein hormone produced predominantly by the kidney in response to hypoxia. While widely known for its hematopo...
www.frontierspartnerships.org
November 25, 2025 at 11:07 AM
Increased Treg in Kidney Transplant Recipients With Erythrocytosis
www.frontierspartnerships.org/journals/tra...
www.frontierspartnerships.org/journals/tra...
JCI - Multiomic analysis reveals a key BCAT1 role in mTOR activation by B cell receptor and TLR9 www.jci.org/articles/vie...
JCI -
Multiomic analysis reveals a key BCAT1 role in mTOR activation by B cell receptor and TLR9
www.jci.org
November 24, 2025 at 2:48 PM
JCI - Multiomic analysis reveals a key BCAT1 role in mTOR activation by B cell receptor and TLR9 www.jci.org/articles/vie...
The Gut–Kidney Axis and Effect on GFR
journals.lww.com/jasn/citatio...
journals.lww.com/jasn/citatio...
journals.lww.com
November 22, 2025 at 10:51 AM
The Gut–Kidney Axis and Effect on GFR
journals.lww.com/jasn/citatio...
journals.lww.com/jasn/citatio...
Purinergic adipocyte-macrophage crosstalk promotes degeneration of thermogenic brown adipose tissue | EMBO reports
www.embopress.org/doi/full/10....
www.embopress.org/doi/full/10....
Purinergic adipocyte-macrophage crosstalk promotes degeneration of thermogenic brown adipose tissue | EMBO reports
imageimageStressed brown adipocytes release extracellular ATP, which acts as a paracrine signal
via P2X4 and P2X7 receptors on macrophages, initiating BAT inflammatory remodeling
and degeneration. Blo...
www.embopress.org
November 22, 2025 at 10:50 AM
Purinergic adipocyte-macrophage crosstalk promotes degeneration of thermogenic brown adipose tissue | EMBO reports
www.embopress.org/doi/full/10....
www.embopress.org/doi/full/10....
Macrophage metabolic reprogramming influences adult growth
www.embopress.org/toc/14693178...
www.embopress.org/toc/14693178...
EMBO reports: Vol 26, No 22
EMBO Press is an editorially independent publishing platform for the development of EMBO scientific publications.
www.embopress.org
November 22, 2025 at 10:48 AM
Macrophage metabolic reprogramming influences adult growth
www.embopress.org/toc/14693178...
www.embopress.org/toc/14693178...
From progression to remission: a new paradigm for success in chronic kidney disease - Kidney International www.kidney-international.org/article/S008...
From progression to remission: a new paradigm for success in chronic kidney disease
Recent advances in treatment of chronic kidney disease have changed the clinical paradigm
from slowing inevitable progression to achievable remission. Landmark trials involving
sodium-glucose cotransp...
www.kidney-international.org
November 18, 2025 at 4:17 PM
From progression to remission: a new paradigm for success in chronic kidney disease - Kidney International www.kidney-international.org/article/S008...
An islet-resident macrophage antioxidant program preserves β cell physiology | Science Immunology www.science.org/doi/10.1126/...
An islet-resident macrophage antioxidant program preserves β cell physiology
SLC7A11 licenses metabolic and antioxidant activities in islet macrophages, supporting β cell insulin secretion and redox homeostasis.
www.science.org
November 18, 2025 at 4:17 PM
An islet-resident macrophage antioxidant program preserves β cell physiology | Science Immunology www.science.org/doi/10.1126/...
A Comprehensive comparative assessment of mean Fluorescence Intensity of Luminex single Antigen bead tests between laboratories and commercial platforms @umaggiore.bsky.social
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
A Comprehensive comparative assessment of mean Fluorescence Intensity of Luminex single Antigen bead tests between laboratories and commercial platforms: A report from the Italian Histocompatibility N...
Reliable and reproducible testing of Donor Specific HLA-Antibodies (DSA) is essential for clinical decisions in organ transplantation. In this prospec…
www.sciencedirect.com
November 17, 2025 at 9:30 PM
A Comprehensive comparative assessment of mean Fluorescence Intensity of Luminex single Antigen bead tests between laboratories and commercial platforms @umaggiore.bsky.social
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...