Charlotte Brierley
ckbrierley.bsky.social
Charlotte Brierley
@ckbrierley.bsky.social
Academic Clinical Lecturer in Haematology, Oxford. Interested in all things myeloid disease and cellular therapy.
Pinned
🚨🚨Paper out! 🚨🚨

Delighted to share our work, now published in ‪@natgenet.nature.com‬ 🧬!
shorturl.at/94s5S

We identified a targetable, chromothripsis-associated genetic event in blast phase (BP) MPN, a particularly poor prognostic subtype of acute leukaemia. 1/n

Illustration: Hratch Arbach
🧵👇
Reposted by Charlotte Brierley
NEW: Researchers at the MRC Molecular Haematology Unit, led by @ckbrierley.bsky.social & @adammead.bsky.social, have uncovered a potential new therapeutic target in BP-MPN - a particularly aggressive type of leukaemia.
🧪🧬

Read more:

@oxfordbrc.bsky.social | @rdm.ox.ac.uk | @medsci.ox.ac.uk
New research reveals druggable target arising from chromosomal rearrangement in aggressive leukaemia
Researchers at the University of Oxford have uncovered a potential new therapeutic target in a particularly aggressive and hard-to-treat form of leukaemia.
www.imm.ox.ac.uk
June 10, 2025 at 9:06 AM
🚨🚨Paper out! 🚨🚨

Delighted to share our work, now published in ‪@natgenet.nature.com‬ 🧬!
shorturl.at/94s5S

We identified a targetable, chromothripsis-associated genetic event in blast phase (BP) MPN, a particularly poor prognostic subtype of acute leukaemia. 1/n

Illustration: Hratch Arbach
🧵👇
June 10, 2025 at 3:26 PM
The Splash @ASH! Stepping out of my comfort zone to flex a fledgling journalistic muscle. Many of the
#ASH24 community have been generous in giving time for interviews and discussion. Now looking fwd to meeting folks in person - and the fab editorial team
#ASHNewsDaily! @ash-hematology.bsky.social
December 7, 2024 at 3:52 PM
Blue skies (perfect for a first post over here 🦋)and beautiful views over Greenland on a plane brimming with haematologists. A peaceful moment ahead of the tumult!
#ASH24
December 7, 2024 at 6:15 AM