Investigadoras do Centro Sigular da USC relatan retos, avances e desigualdades con motivo do Día da Muller e a Nena na Ciencia

1610 outstanding postdoctoral researchers were selected for funding among 17,066 applicants.

Prodrug strategies traditionally rely on masking polar functional groups of bioactive molecules with protecting units that can be removed by specific stimuli in biological settings. Here, we introduce...

Prodrug strategies traditionally rely on masking polar functional groups of bioactive molecules with protecting units that can be removed by specific stimuli in biological settings. Here, we introduce an alternative uncaging approach that bypasses the need for heteroatom handles, based on reversible masking of aromatic C–H bonds with thianthrenium groups. Unmasking is triggered by low-energy photoredox activation, which generates aryl radicals that are rapidly reduced by endogenous bioreductants to restore the native C–H bond. Beyond establishing the feasibility of photoredox radical chemistry in living cells, we demonstrate a proof-of-concept application of this strategy for the modulation of activity of antifungal agents.

The Master’s Degree in Chemistry at the Interface with Biology and Materials Science (ChemBio&Mat) held its closing events last week, marking the end of its sixth edition. On Friday, January 30,

The Center for Research in Biological Chemistry and Molecular Materials (CiQUS) at the University of Santiago de Compostela (USC) has secured a new Proof of Concept (PoC) grant from the European

Inserting, removing or swapping individual atoms from the core of a molecule is a long-standing challenge in chemistry. This process, called skeletal editing,…

O despliegue das enerxías renovables e a modernización das redes eléctricas están a incrementar de forma notable a demanda de sistemas de almacenamento fiables, duradeiros e sostibles. Non obstante,

Un proxecto liderado dende a USC explora novos materiais para integrar almacenamento e cálculo nun mesmo dispositivo