Bart Brouwer
brouwerb.bsky.social
Bart Brouwer
@brouwerb.bsky.social
Postdoc | Artificial Enzyme Design | Drienovská lab | VU Amsterdam 🇳🇱

Previously: PhD | Roelfes Group | RuG
Reposted by Bart Brouwer
🚨 preprint 2️⃣ this month: our (purely experimental🧪) venture into #ChemBio
We prouldy present: ADD-tagging of proteins (or "ADDing") —a super convenient enzymatic technique to install click chemistry handles on proteins.
Led by superstar @wahyuwidodo.bsky.social
www.biorxiv.org/content/10.1...
A 🧵👇🏽
May 20, 2025 at 12:30 PM
Reposted by Bart Brouwer
📢📢📢 PhD Opportunity!

Join our research group at RUG! We're seeking a motivated PhD student for a project on biocatalytic cascade processes combining natural and designer enzymes, supported by machine learning.
Click below to learn more — and feel free to share!

sites.google.com/rug.nl/roelf...
Roelfes group - Open Positions
PhD position on Hybrid biocatalytic cascades aided by Machine learning (1.0 FTE)
sites.google.com
May 12, 2025 at 9:10 AM
Very proud to share that one of my main PhD projects has been published in @chemicalscience.rsc.org, and that it has been selected as a #ChemSciPicks of the week paper!

Keep reading below for more details, or check out the full paper for free online: doi.org/10.1039/D5SC...

Thread ⬇️
Check out this week’s #ChemSciPicks from Gerard Roelfes (@roelfesgroup.bsky.social, @stratinghinst.bsky.social) et al.!

‘Genetically Encoded 3-Aminotyrosine as Catalytic Residue in a Designer Friedel-Crafts Alkylase’

Read it here for free: doi.org/10.1039/D5SC...

#ChemSky 🧪
April 23, 2025 at 9:17 AM
Reposted by Bart Brouwer
Grateful to be part of this awesome project lead by @brouwerb.bsky.social. Take a look to our preprint about unlocking iminium ion catalysis when using amino-tyrosine as a genetically encoded amino acid! 🤓
#MSCA @roelfesgroup.bsky.social
Check out our latest preprint, in which we demonstrate the first example of using noncanonical 3-aminotyrosine (aY) as a catalytic residue for iminium activation in a designer enzyme!

Thread ⬇️
February 12, 2025 at 8:31 AM
Check out our latest preprint, in which we demonstrate the first example of using noncanonical 3-aminotyrosine (aY) as a catalytic residue for iminium activation in a designer enzyme!

Thread ⬇️
February 11, 2025 at 8:05 PM