Bianca Dumitrascu
@bimidu.bsky.social
computational biologist and statistician interested in how genes encode shape, form, and dynamics during development and regeneration; assistant professor @Columbia University https://www.morpho-lab.com/
Pinned
Bianca Dumitrascu
@bimidu.bsky.social
· Dec 24
Patches: A Representation Learning framework for Decoding Shared and Condition-Specific Transcriptional Programs in Wound Healing
Single-cell genomics enables the study of cell states and cell state transitions across biological conditions like aging, drug treatment, or injury. However, existing computational methods often strug...
www.biorxiv.org
Check out our newest preprint on #bioxiv. We developed Patches, a tool for extracting joint and condition specific signatures from scRNA-seq data in complex experimental designs like wound healing: www.biorxiv.org/content/10.1...
GitHub: github.com/Computationa...
GitHub: github.com/Computationa...
Our fantastic postdoc Lambda talking about her adventure to find multi-scale signals in spatial transcriptomics at CSHL Single Cell Analysis. Preprint coming out soon! 😊 🚀 🚲
November 14, 2025 at 9:45 PM
Our fantastic postdoc Lambda talking about her adventure to find multi-scale signals in spatial transcriptomics at CSHL Single Cell Analysis. Preprint coming out soon! 😊 🚀 🚲
An exciting collaboration with a wonderful team! Check out Kuba's tutorial!
🧵1/14 Preprint thread! Can we predict a cell’s fate based on its dynamics? 🔮 Our new study unveils a framework for watching development unfold in real-time, revealing how a cell's shape and movement encode info about its future fate. 🔬📄 Preprint: tinyurl.com/4shf8v4x
September 22, 2025 at 5:59 PM
An exciting collaboration with a wonderful team! Check out Kuba's tutorial!
Reposted by Bianca Dumitrascu
Latest from the lab: a review led by @jamesehammond.bsky.social on the evolvability of vertebral counts and the developmental processes that make it possible.
Latest work:
Review on the evolvability of vertebral number, and the developmental processes underpinning it
Written by Callum Bucklow, @bertaverd.bsky.social, and myself
Check it out here: doi.org/10.32942/X2K...
Review on the evolvability of vertebral number, and the developmental processes underpinning it
Written by Callum Bucklow, @bertaverd.bsky.social, and myself
Check it out here: doi.org/10.32942/X2K...
March 25, 2025 at 10:29 AM
Latest from the lab: a review led by @jamesehammond.bsky.social on the evolvability of vertebral counts and the developmental processes that make it possible.
Reposted by Bianca Dumitrascu
Thrilled to announce that I am looking for a Research Technician/Assistant to join my lab @imbavienna.bsky.social. Please consider applying if you’re enthusiastic about #devbio #stemcells #teamwork and excited to help shaping a new lab!
Thankful for any retweet! 🫶
imba.onlyfy.jobs/job/l6u2m980
Thankful for any retweet! 🫶
imba.onlyfy.jobs/job/l6u2m980
March 20, 2025 at 12:13 PM
Thrilled to announce that I am looking for a Research Technician/Assistant to join my lab @imbavienna.bsky.social. Please consider applying if you’re enthusiastic about #devbio #stemcells #teamwork and excited to help shaping a new lab!
Thankful for any retweet! 🫶
imba.onlyfy.jobs/job/l6u2m980
Thankful for any retweet! 🫶
imba.onlyfy.jobs/job/l6u2m980
Congratulations Kristina and happy for those lucky to join your group!
Amidst these troubling times, I have some positive personal news to share: I will be joining @imbavienna.bsky.social as a new group leader this fall! 🎉 I am excited for fun projects, surprising discoveries, and great discussions within the fantastic science community @vbcscitraining.bsky.social
Kristina Stapornwongkul is joining IMBA! The Stapornwongkul lab will study how the nutritional environment and metabolic processes influence embryonic development—an emerging research area with broad implications for both fundamental biology and biomedical applications. Welcome, Kristina!
March 20, 2025 at 7:10 PM
Congratulations Kristina and happy for those lucky to join your group!
Thank you so much for the highlight and for the nice summary of our recent work!
March 19, 2025 at 5:51 PM
Thank you so much for the highlight and for the nice summary of our recent work!
Reposted by Bianca Dumitrascu
Dr. Bianca Dumitrascu (bimidu.bsky.social) led a new study published in naturemethods.bsky.social on a computational pipeline linking spatial transcriptomics + mechanical forces in tissue development. Read more: bit.ly/4kCgT1q #CancerResearch #Mechanobiology #SpatialTranscriptomics #IICDColumbia
Bridging Biology and Biomechanics: The Dumitrascu Lab’s New Computational Framework Illuminates Tissue Development | Columbia University
bit.ly
March 18, 2025 at 4:52 PM
Dr. Bianca Dumitrascu (bimidu.bsky.social) led a new study published in naturemethods.bsky.social on a computational pipeline linking spatial transcriptomics + mechanical forces in tissue development. Read more: bit.ly/4kCgT1q #CancerResearch #Mechanobiology #SpatialTranscriptomics #IICDColumbia
Some light yesterday at Chimamanda Ngozi Adichie's new book reading.
March 12, 2025 at 6:31 PM
Some light yesterday at Chimamanda Ngozi Adichie's new book reading.
What a treat to be part of this effort! Congratulations @jcornwallscoones.bsky.social and team!
Excited to share my latest work with @joadelas.bsky.social and @jamesbriscoe.bsky.social
Predictable Engineering of Signal-Dependent Cis-Regulatory Elements
www.biorxiv.org/content/10.1...
1/11
Predictable Engineering of Signal-Dependent Cis-Regulatory Elements
www.biorxiv.org/content/10.1...
1/11
Predictable Engineering of Signal-Dependent Cis-Regulatory Elements
www.biorxiv.org
March 10, 2025 at 1:35 PM
What a treat to be part of this effort! Congratulations @jcornwallscoones.bsky.social and team!
Check out our newest preprint on #bioxiv. We developed Patches, a tool for extracting joint and condition specific signatures from scRNA-seq data in complex experimental designs like wound healing: www.biorxiv.org/content/10.1...
GitHub: github.com/Computationa...
GitHub: github.com/Computationa...
Patches: A Representation Learning framework for Decoding Shared and Condition-Specific Transcriptional Programs in Wound Healing
Single-cell genomics enables the study of cell states and cell state transitions across biological conditions like aging, drug treatment, or injury. However, existing computational methods often strug...
www.biorxiv.org
December 24, 2024 at 3:02 PM
Check out our newest preprint on #bioxiv. We developed Patches, a tool for extracting joint and condition specific signatures from scRNA-seq data in complex experimental designs like wound healing: www.biorxiv.org/content/10.1...
GitHub: github.com/Computationa...
GitHub: github.com/Computationa...
Very excited about this first adventure in looking at regeneration! Thank you Maria and @smeetonlab.bsky.social for a fantastic first collaborative project :)
📢🧪For your holiday travel reading, check out our new pre-print! Using a new joint resection injury model, we describe an innate regeneration program in adult #zebrafish that reestablishes all major synovial joint cell types, including lubricated articular cartilage. www.biorxiv.org/content/10.1...
www.biorxiv.org
December 24, 2024 at 2:34 PM
Very excited about this first adventure in looking at regeneration! Thank you Maria and @smeetonlab.bsky.social for a fantastic first collaborative project :)