Navjot Kaur
@babyamygdala.bsky.social
Associate Research Scientist in Nenad Sestan Lab at Yale University. Interested in Amygdala, Claustrum and Insula Development and their connectivity. Love Tracing and Tracking Neurons. Views are my own.
Pinned
Navjot Kaur
@babyamygdala.bsky.social
· Jan 15
Specification of claustro-amygdalar and palaeocortical neurons and circuits - Nature
A conserved gene regulatory network involving SOX4, SOX11 and TFAP2D shapes the development of excitatory neurons in ventrolateral pallium and their connectivity with the prefrontal cortex.
nature.com
Navjot Kaur
I am thrilled to share our latest paper from Sestan lab on the development of the claustro-amygdalar complex, is published at nature.com/articles/s41.... A big thank you to all our collaborators and mentors.
@marinap63.bsky.social
I am thrilled to share our latest paper from Sestan lab on the development of the claustro-amygdalar complex, is published at nature.com/articles/s41.... A big thank you to all our collaborators and mentors.
@marinap63.bsky.social
Reposted by Navjot Kaur
Still think brain regions don’t exist? That everything is everywhere? That cell types don’t matter and that everything is a dynamical phase portrait?
Wrong.
Interconnected brain modules exist at the level of fine grained transcriptomics. www.nature.com/articles/s41...
Wrong.
Interconnected brain modules exist at the level of fine grained transcriptomics. www.nature.com/articles/s41...
Whole-cortex in situ sequencing reveals input-dependent area identity - Nature
BARseq interrogates the expression of 104 cell-type marker genes in 10.3 million cells over nine mouse forebrain hemispheres to reveal the role of peripheral inputs on cortical area development.
www.nature.com
November 6, 2025 at 12:39 PM
Still think brain regions don’t exist? That everything is everywhere? That cell types don’t matter and that everything is a dynamical phase portrait?
Wrong.
Interconnected brain modules exist at the level of fine grained transcriptomics. www.nature.com/articles/s41...
Wrong.
Interconnected brain modules exist at the level of fine grained transcriptomics. www.nature.com/articles/s41...
Reposted by Navjot Kaur
🧠✨ Genetic Tools Atlas 3.0 is here!
The GTA now has an additional 750 datasets, including 80+ mouse whole-brain light sheet microscopy images as well as the first macaque datasets.
🔗 https://portal.brain-map.org/genetic-tools/genetic-tools-atlas
#neuroskyence
The GTA now has an additional 750 datasets, including 80+ mouse whole-brain light sheet microscopy images as well as the first macaque datasets.
🔗 https://portal.brain-map.org/genetic-tools/genetic-tools-atlas
#neuroskyence
November 2, 2025 at 3:46 PM
🧠✨ Genetic Tools Atlas 3.0 is here!
The GTA now has an additional 750 datasets, including 80+ mouse whole-brain light sheet microscopy images as well as the first macaque datasets.
🔗 https://portal.brain-map.org/genetic-tools/genetic-tools-atlas
#neuroskyence
The GTA now has an additional 750 datasets, including 80+ mouse whole-brain light sheet microscopy images as well as the first macaque datasets.
🔗 https://portal.brain-map.org/genetic-tools/genetic-tools-atlas
#neuroskyence
Reposted by Navjot Kaur
We often think of problems as separate buckets: disease, malnutrition, affordability or economic development. But “Climate change is not a separate bucket,” Hayhoe says. “The reason we care about climate change is that it’s the hole in every bucket.”
November 2, 2025 at 5:33 PM
We often think of problems as separate buckets: disease, malnutrition, affordability or economic development. But “Climate change is not a separate bucket,” Hayhoe says. “The reason we care about climate change is that it’s the hole in every bucket.”
Reposted by Navjot Kaur
Psychedelics disrupt the link between vascular and neuronal activity, which complicates interpretations of fMRI data. Adopting a more holistic view of what constitutes brain activity may help.
By @callimcflurry.bsky.social
#neuroskyence
www.thetransmitter.org/psychedelics...
By @callimcflurry.bsky.social
#neuroskyence
www.thetransmitter.org/psychedelics...
Psychedelics muddy fMRI results: Q&A with Adam Bauer and Jonah Padawer-Curry
The drugs disrupt the link between vascular and neuronal activity, which complicates interpretations of fMRI data. Adopting a more holistic view of what constitutes brain activity may help…
www.thetransmitter.org
October 29, 2025 at 6:05 PM
Psychedelics disrupt the link between vascular and neuronal activity, which complicates interpretations of fMRI data. Adopting a more holistic view of what constitutes brain activity may help.
By @callimcflurry.bsky.social
#neuroskyence
www.thetransmitter.org/psychedelics...
By @callimcflurry.bsky.social
#neuroskyence
www.thetransmitter.org/psychedelics...
Reposted by Navjot Kaur
Pharmaceutical industry money can’t replace NIH funding | STAT share.google/iZfAlSgXeIR3...
#BasicScience #NIH #NSF #NASA #JOBS #RESEARCHFUNDING #RESEARCHMATTERS #InnovationNation #AmericaFirst
#BasicScience #NIH #NSF #NASA #JOBS #RESEARCHFUNDING #RESEARCHMATTERS #InnovationNation #AmericaFirst
Corporate support cannot make up for threats to the NIH budget
The privatization of medical research can’t replace what the NIH has provided.
share.google
October 24, 2025 at 10:40 AM
Pharmaceutical industry money can’t replace NIH funding | STAT share.google/iZfAlSgXeIR3...
#BasicScience #NIH #NSF #NASA #JOBS #RESEARCHFUNDING #RESEARCHMATTERS #InnovationNation #AmericaFirst
#BasicScience #NIH #NSF #NASA #JOBS #RESEARCHFUNDING #RESEARCHMATTERS #InnovationNation #AmericaFirst
Reposted by Navjot Kaur
How Jane Goodall changed the way we see animals - and the world by @rowhoop.bsky.social for @newscientist.com
www.newscientist.com/article/2498...
www.newscientist.com/article/2498...
How Jane Goodall changed the way we see animals - and the world
Jane Goodall, who chronicled the social lives of chimps, has died, but has left a lasting legacy on how we view the natural world
www.newscientist.com
October 2, 2025 at 10:07 AM
How Jane Goodall changed the way we see animals - and the world by @rowhoop.bsky.social for @newscientist.com
www.newscientist.com/article/2498...
www.newscientist.com/article/2498...
Reposted by Navjot Kaur
A spatially resolved transcriptomic atlas of the primate amygdala (human, macaque, and baboon) now out in Science Advances (www.science.org/doi/10.1126/...). The amygdala contains 32 types of neurons with many neuron types specific to particular subdivisions.
Lots of updates from the preprint!
Lots of updates from the preprint!
Transcriptomic diversity of amygdalar subdivisions across humans and nonhuman primates
Specialized cell types and links to psychiatric disorders are revealed by genetic mapping of primate amygdala neurons.
www.science.org
September 17, 2025 at 7:31 PM
A spatially resolved transcriptomic atlas of the primate amygdala (human, macaque, and baboon) now out in Science Advances (www.science.org/doi/10.1126/...). The amygdala contains 32 types of neurons with many neuron types specific to particular subdivisions.
Lots of updates from the preprint!
Lots of updates from the preprint!
Reposted by Navjot Kaur
Very excited to share my second postdoc, now out in Science Advances! We used targeted snRNA-seq to profile four major subnuclei of the primate across three species (including humans). 1/13 www.science.org/doi/10.1126/...
Transcriptomic diversity of amygdalar subdivisions across humans and nonhuman primates
Specialized cell types and links to psychiatric disorders are revealed by genetic mapping of primate amygdala neurons.
www.science.org
September 18, 2025 at 1:10 AM
Very excited to share my second postdoc, now out in Science Advances! We used targeted snRNA-seq to profile four major subnuclei of the primate across three species (including humans). 1/13 www.science.org/doi/10.1126/...
Beautiful work out from Sestan lab!!
Thrilled to present MIND!
A model for how the sensorimotor–association axis of the neocortex develops.
Huge thanks to the incredible multidisciplinary team who made this happen.
www.biorxiv.org/content/10.1...
A model for how the sensorimotor–association axis of the neocortex develops.
Huge thanks to the incredible multidisciplinary team who made this happen.
www.biorxiv.org/content/10.1...
Competing Programs Shape Cortical Sensorimotor-Association Axis Development
The neocortex is organized along a dominant sensorimotor-to-association (S-A) axis, anchored by modality-specific primary sensorimotor areas at one end and transmodal association areas that form distr...
www.biorxiv.org
July 1, 2025 at 5:34 PM
Beautiful work out from Sestan lab!!
Reposted by Navjot Kaur
Asked about his decision to fire the entire vaccine advisory committee of the CDC, RFK Jr. asserted that "children get between 69 and 92 vaccines before they’re 18," among other lies.
Fact check: the number is closer to between 24 and 50.
https://trib.al/uUQLOgI
Fact check: the number is closer to between 24 and 50.
https://trib.al/uUQLOgI
After Purging Key Vaccine Panel, RFK Jr. Moves to Assert Control
The HHS chief went on Fox News to repeatedly lie about vaccines and the members of an advisory committee he recently purged.
trib.al
June 14, 2025 at 1:56 PM
Asked about his decision to fire the entire vaccine advisory committee of the CDC, RFK Jr. asserted that "children get between 69 and 92 vaccines before they’re 18," among other lies.
Fact check: the number is closer to between 24 and 50.
https://trib.al/uUQLOgI
Fact check: the number is closer to between 24 and 50.
https://trib.al/uUQLOgI
Reposted by Navjot Kaur
A wave of emotion | Science www.science.org/doi/10.1126/...
A wave of emotion
Sustained brainwide patterns of activity enable emotions to outlast their triggers
www.science.org
May 30, 2025 at 9:19 AM
A wave of emotion | Science www.science.org/doi/10.1126/...
Reposted by Navjot Kaur
Just published, expansion in situ genome sequencing, where you can sequence DNA while still inside the cell, mapping its organization relative to proteins and other markers, with the help of expansion microscopy! Led by @jbuenrostro.bksy.social. www.science.org/doi/10.1126/...
May 30, 2025 at 11:37 AM
Just published, expansion in situ genome sequencing, where you can sequence DNA while still inside the cell, mapping its organization relative to proteins and other markers, with the help of expansion microscopy! Led by @jbuenrostro.bksy.social. www.science.org/doi/10.1126/...
Reposted by Navjot Kaur
My med school textbook says stimulants like Ritalin treat hyperactivity by “stimulating” the brain’s attention and cognitive control systems. We studied children taking stimulants in the ABCD Study, and the largest differences were actually in arousal and reward networks! Check out our preprint!
May 22, 2025 at 9:33 PM
My med school textbook says stimulants like Ritalin treat hyperactivity by “stimulating” the brain’s attention and cognitive control systems. We studied children taking stimulants in the ABCD Study, and the largest differences were actually in arousal and reward networks! Check out our preprint!
Excited to showcase as a co-first author our latest work "Adaptive Evolution of Gene Regulatory Networks in Mammalian Neocortical Neurons "https://www.biorxiv.org/content/10.1101/2025.05.20.652233v1
May 22, 2025 at 5:43 PM
Excited to showcase as a co-first author our latest work "Adaptive Evolution of Gene Regulatory Networks in Mammalian Neocortical Neurons "https://www.biorxiv.org/content/10.1101/2025.05.20.652233v1
Reposted by Navjot Kaur
Day 25 (a need): Psychiatric conditions are diagnosed based on symptoms rather than biological tests like brain scans or blood tests.
We do not yet know enough about what's happening in the brain of someone experiencing a depressive episode or psychosis to create such a test.
#ElusiveCures30
We do not yet know enough about what's happening in the brain of someone experiencing a depressive episode or psychosis to create such a test.
#ElusiveCures30
May 16, 2025 at 11:10 AM
Day 25 (a need): Psychiatric conditions are diagnosed based on symptoms rather than biological tests like brain scans or blood tests.
We do not yet know enough about what's happening in the brain of someone experiencing a depressive episode or psychosis to create such a test.
#ElusiveCures30
We do not yet know enough about what's happening in the brain of someone experiencing a depressive episode or psychosis to create such a test.
#ElusiveCures30
Reposted by Navjot Kaur
Einstein:
Scientists should not be silent about human affairs.
Science shouldn’t be partisan, but scientists should embrace values that improve humanity.
Science affects people and the people — humanity — affect science.
Scientists should not be silent about human affairs.
Science shouldn’t be partisan, but scientists should embrace values that improve humanity.
Science affects people and the people — humanity — affect science.
"I do not share your view that the Scientist should observe silence in political matters, i.e. human affairs in the broadest sense. The situation shows whither this restraint will lead: to the surrender of leadership, without any resistance, to those who are blind or irresponsible.”
-Einstein, 1933
-Einstein, 1933
April 7, 2025 at 12:20 AM
Einstein:
Scientists should not be silent about human affairs.
Science shouldn’t be partisan, but scientists should embrace values that improve humanity.
Science affects people and the people — humanity — affect science.
Scientists should not be silent about human affairs.
Science shouldn’t be partisan, but scientists should embrace values that improve humanity.
Science affects people and the people — humanity — affect science.
Reposted by Navjot Kaur
Podcast interview with me about spatial planning in London taxi drivers: youtube.com/watch?v=6gUR...
London black cabs beat AI to show 'genius of human mind' ...The Standard podcast
YouTube video by The London Standard
youtube.com
March 15, 2025 at 9:58 AM
Podcast interview with me about spatial planning in London taxi drivers: youtube.com/watch?v=6gUR...
Reposted by Navjot Kaur
In fiscal year 2024, the report found, NIH awarded more than $36.9 billion to researchers, supporting more than 408,000 jobs and generating over $94.5 billion in new economic activity nationwide.
news.harvard.edu/gazette/stor...
news.harvard.edu/gazette/stor...
NIH funding delivers exponential economic returns — Harvard Gazette
Report finds all 50 states reap gains in patient health, job creation, research resources, business development.
news.harvard.edu
March 12, 2025 at 11:49 PM
In fiscal year 2024, the report found, NIH awarded more than $36.9 billion to researchers, supporting more than 408,000 jobs and generating over $94.5 billion in new economic activity nationwide.
news.harvard.edu/gazette/stor...
news.harvard.edu/gazette/stor...
Reposted by Navjot Kaur
Excited to share this brief review where @katieinsel.bsky.social & I discuss studying adolescence to understand how brains work! We highlight avenues for future collaborative work at the intersection of cognitive, computational, & developmental neuroscience 🧠
journals.sagepub.com/doi/10.1177/...
journals.sagepub.com/doi/10.1177/...
March 10, 2025 at 6:31 PM
Excited to share this brief review where @katieinsel.bsky.social & I discuss studying adolescence to understand how brains work! We highlight avenues for future collaborative work at the intersection of cognitive, computational, & developmental neuroscience 🧠
journals.sagepub.com/doi/10.1177/...
journals.sagepub.com/doi/10.1177/...
Reposted by Navjot Kaur
When you've been in the cell culture hood all day and finally get to take off your gloves:
March 6, 2025 at 8:21 PM
When you've been in the cell culture hood all day and finally get to take off your gloves:
Reposted by Navjot Kaur
@michellemonje.bsky.social at @stanfordmedicine.bsky.social and Frank Winkler at Heidelberg University have won the 2025 @brainprize.bsky.social from the Lundbeck Foundation for their work in cancer neuroscience.
By @sydneywyatt.bsky.social
#neuroskyence
www.thetransmitter.org/community/20...
By @sydneywyatt.bsky.social
#neuroskyence
www.thetransmitter.org/community/20...
2025 Brain Prize honors pair of cancer neuroscientists
Michelle Monje and Frank Winkler share the $1.4 million award for their discovery of synapses between brain cancer cells and neurons.
www.thetransmitter.org
March 5, 2025 at 3:10 PM
@michellemonje.bsky.social at @stanfordmedicine.bsky.social and Frank Winkler at Heidelberg University have won the 2025 @brainprize.bsky.social from the Lundbeck Foundation for their work in cancer neuroscience.
By @sydneywyatt.bsky.social
#neuroskyence
www.thetransmitter.org/community/20...
By @sydneywyatt.bsky.social
#neuroskyence
www.thetransmitter.org/community/20...
Reposted by Navjot Kaur
I’m excited to share our publication from @dulaclab.bsky.social in @nature.com, where we illuminate the development of hypothalamic cell types involved in a broad range of functions, from social behaviors to thirst, thermoregulation, and sleep. Highlights below! 🧵
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Sensory input, sex and function shape hypothalamic cell type development - Nature
Paired transcriptomic and chromatin accessibility profiling are used to examine the developmental trajectories of neuronal populations in the hypothalamic preoptic region, including cell types with ke...
www.nature.com
March 5, 2025 at 10:04 PM
I’m excited to share our publication from @dulaclab.bsky.social in @nature.com, where we illuminate the development of hypothalamic cell types involved in a broad range of functions, from social behaviors to thirst, thermoregulation, and sleep. Highlights below! 🧵
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Navjot Kaur
It continues to get worse. We can’t breathe a sigh of relief because it isn’t MY grant. We all risk being on the chopping block. Not even to mention the severe detriment to science, society, etc. 😢
www.nature.com/articles/d41...
www.nature.com/articles/d41...
Exclusive: NIH to terminate hundreds of active research grants
Studies that touch on LGBT+ health, gender identity and DEI in the biomedical workforce could be terminated, according to documents obtained by Nature.
www.nature.com
March 6, 2025 at 5:55 AM
It continues to get worse. We can’t breathe a sigh of relief because it isn’t MY grant. We all risk being on the chopping block. Not even to mention the severe detriment to science, society, etc. 😢
www.nature.com/articles/d41...
www.nature.com/articles/d41...
Reposted by Navjot Kaur
New work by @gozziale.bsky.social on the phenotypic heterogeneity in autism spectrum disorder and underlying processes, with two major subtypes—hypo- & hyper-connectivity—linked to synaptic dysfunction transcriptional regulation/chromatin remodeling, respectively 🧪🧠🧬
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Biological subtyping of autism via cross-species fMRI
It is frequently assumed that the phenotypic heterogeneity in autism spectrum disorder reflects underlying pathobiological variation. However, direct evidence in support of this hypothesis is lacking....
www.biorxiv.org
March 6, 2025 at 9:09 AM
New work by @gozziale.bsky.social on the phenotypic heterogeneity in autism spectrum disorder and underlying processes, with two major subtypes—hypo- & hyper-connectivity—linked to synaptic dysfunction transcriptional regulation/chromatin remodeling, respectively 🧪🧠🧬
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Navjot Kaur
Poor old Pavlov. Eventually every time he heard a bell ring he wanted to feed a dog.
February 23, 2025 at 9:59 PM
Poor old Pavlov. Eventually every time he heard a bell ring he wanted to feed a dog.