A. Berçin Barlas
@aysebercinb.bsky.social
Postdoctoral Researcher @Izmir Biomedicine and Genome Center - Computational Structural Biology Lab.
Reposted by A. Berçin Barlas
And the legacy continues! 😊
@amjjbonvin.bsky.social @bioinfo.se @lindorfflarsen.bsky.social #EMBOIntegMod25 ! 🍀🧿
@amjjbonvin.bsky.social @bioinfo.se @lindorfflarsen.bsky.social #EMBOIntegMod25 ! 🍀🧿
October 6, 2025 at 1:13 PM
And the legacy continues! 😊
@amjjbonvin.bsky.social @bioinfo.se @lindorfflarsen.bsky.social #EMBOIntegMod25 ! 🍀🧿
@amjjbonvin.bsky.social @bioinfo.se @lindorfflarsen.bsky.social #EMBOIntegMod25 ! 🍀🧿
🚀 Excited to share that our article with @ezgikaraca.bsky.social is now published in Communications Biology!
In this study, we explored DNA readout rules of almost identical DNMT3A and DNMT3B (91% sequence similarity!), and we asked: how can nearly the same proteins “see” DNA so differently? 🧬✨
In this study, we explored DNA readout rules of almost identical DNMT3A and DNMT3B (91% sequence similarity!), and we asked: how can nearly the same proteins “see” DNA so differently? 🧬✨
Comparative dynamics analysis identifies key residues driving sequence specificity differences between human DNA methyltransferases DNMT3A and DNMT3B.
@aysebercinb.bsky.social
@ezgikaraca.bsky.social
www.nature.com/articles/s42...
@aysebercinb.bsky.social
@ezgikaraca.bsky.social
www.nature.com/articles/s42...
So close yet so far apart: distinct flanking sequence recognition by DNMT3A and DNMT3B - Communications Biology
Comparative dynamics analysis identifies key residues driving sequence specificity differences between human DNA methyltransferases DNMT3A and DNMT3B.
www.nature.com
August 22, 2025 at 10:48 AM
🚀 Excited to share that our article with @ezgikaraca.bsky.social is now published in Communications Biology!
In this study, we explored DNA readout rules of almost identical DNMT3A and DNMT3B (91% sequence similarity!), and we asked: how can nearly the same proteins “see” DNA so differently? 🧬✨
In this study, we explored DNA readout rules of almost identical DNMT3A and DNMT3B (91% sequence similarity!), and we asked: how can nearly the same proteins “see” DNA so differently? 🧬✨