AJ Simon
@ayejaysimon.bsky.social
Neuroscience PhD candidate at Yale
Brain networks, cognition, psychiatry
Constable Lab
NSF GRFP fellow
Formerly @Neuroscapeucsf
Twitter: @ayejaysimon
Brain networks, cognition, psychiatry
Constable Lab
NSF GRFP fellow
Formerly @Neuroscapeucsf
Twitter: @ayejaysimon
Reposted by AJ Simon
Congrats, great choices for Cogneuro research:
October 29, 2025 at 2:02 PM
Congrats, great choices for Cogneuro research:
Reposted by AJ Simon
Great piece by @natolambert.bsky.social on the current state of human exhaustion in the AI world. Makes this important point:
October 25, 2025 at 3:05 PM
Great piece by @natolambert.bsky.social on the current state of human exhaustion in the AI world. Makes this important point:
Reposted by AJ Simon
BOLD signal changes can oppose oxygen metabolism across the human cortex | bioRxiv www.biorxiv.org/content/10.1...
October 22, 2025 at 12:41 AM
BOLD signal changes can oppose oxygen metabolism across the human cortex | bioRxiv www.biorxiv.org/content/10.1...
Reposted by AJ Simon
Excited to share our new preprint! We conducted a spatial meta-analysis of community violence and mental health, synthesizing 155 articles (k = 769) to test how exposure to community violence is associated with mental health problems, and how state social service investments moderate the link. 💵
The role of state social service spending in moderating mental health outcomes of community violence: a spatial meta-analysis: https://doi.org/10.31234/osf.io/zr94j_v1
October 20, 2025 at 1:30 PM
Excited to share our new preprint! We conducted a spatial meta-analysis of community violence and mental health, synthesizing 155 articles (k = 769) to test how exposure to community violence is associated with mental health problems, and how state social service investments moderate the link. 💵
Reposted by AJ Simon
Excited to share our new paper entitled Multisystem Environmental Factors Elucidate Shared and Distinct Associations With Brain and Behavior in Adolescents.
Link: www.jaacap.org/article/S089....
@kavliatyale.bsky.social
Link: www.jaacap.org/article/S089....
@kavliatyale.bsky.social
October 16, 2025 at 9:41 PM
Excited to share our new paper entitled Multisystem Environmental Factors Elucidate Shared and Distinct Associations With Brain and Behavior in Adolescents.
Link: www.jaacap.org/article/S089....
@kavliatyale.bsky.social
Link: www.jaacap.org/article/S089....
@kavliatyale.bsky.social
Reposted by AJ Simon
thrilled to share our preprint on false memories in naturalistic recollection!
Distinct paths to false memory revealed in hundreds of narrative recalls
paper: doi.org/10.31234/osf...
w/ phoebehc.bsky.social (co-first) Vy A. Vo @davidpoeppel.bsky.social @toddgureckis.bsky.social
thread below 👇
Distinct paths to false memory revealed in hundreds of narrative recalls
paper: doi.org/10.31234/osf...
w/ phoebehc.bsky.social (co-first) Vy A. Vo @davidpoeppel.bsky.social @toddgureckis.bsky.social
thread below 👇
October 16, 2025 at 7:29 PM
thrilled to share our preprint on false memories in naturalistic recollection!
Distinct paths to false memory revealed in hundreds of narrative recalls
paper: doi.org/10.31234/osf...
w/ phoebehc.bsky.social (co-first) Vy A. Vo @davidpoeppel.bsky.social @toddgureckis.bsky.social
thread below 👇
Distinct paths to false memory revealed in hundreds of narrative recalls
paper: doi.org/10.31234/osf...
w/ phoebehc.bsky.social (co-first) Vy A. Vo @davidpoeppel.bsky.social @toddgureckis.bsky.social
thread below 👇
Reposted by AJ Simon
Why do brain networks vary? Do these differences shape behavior? If every 🧠 is unique, how can we detect common features of brain organization?
@rodbraga.bsky.social and I dig in, in @annualreviews.bsky.social (ahead of print):
go.illinois.edu/Gratton2025-...
#neuroskyence #psychscisky #MedSky
🧵👇
@rodbraga.bsky.social and I dig in, in @annualreviews.bsky.social (ahead of print):
go.illinois.edu/Gratton2025-...
#neuroskyence #psychscisky #MedSky
🧵👇
Dense Phenotyping of Human Brain Network Organization Using Precision fMRI
The advent of noninvasive imaging methods like functional magnetic resonance imaging (fMRI) transformed cognitive neuroscience, providing insights into large-scale brain networks and their link to cog...
go.illinois.edu
October 16, 2025 at 3:00 PM
Why do brain networks vary? Do these differences shape behavior? If every 🧠 is unique, how can we detect common features of brain organization?
@rodbraga.bsky.social and I dig in, in @annualreviews.bsky.social (ahead of print):
go.illinois.edu/Gratton2025-...
#neuroskyence #psychscisky #MedSky
🧵👇
@rodbraga.bsky.social and I dig in, in @annualreviews.bsky.social (ahead of print):
go.illinois.edu/Gratton2025-...
#neuroskyence #psychscisky #MedSky
🧵👇
Couldn’t agree more. It’s easy to blame the “other” side for not trusting scientists, but to begin to repair these fractures it’s our responsibility to step up and be leaders and engage with the community
A thought-provoking piece in Nature Neuroscience by many neuroscience colleagues: "Science must break its silence to rebuild public trust". Lots to think about here.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
October 15, 2025 at 2:30 PM
Couldn’t agree more. It’s easy to blame the “other” side for not trusting scientists, but to begin to repair these fractures it’s our responsibility to step up and be leaders and engage with the community
Reposted by AJ Simon
Beautiful example of fMRI-based stratification for precision psychiatry!
www.nature.com/articles/s44...
www.nature.com/articles/s44...
October 13, 2025 at 4:14 PM
Beautiful example of fMRI-based stratification for precision psychiatry!
www.nature.com/articles/s44...
www.nature.com/articles/s44...
Reposted by AJ Simon
This is a fascinating study dissecting the degree to which functional connectivity in EEG is driven by aperiodic activity instead of oscillations -- how robust are connectivity findings in a frequency band (theta, alpha) when oscillations are not omni-present?
www.jneurosci.org/content/earl...
www.jneurosci.org/content/earl...
Functional connectivity is dominated by aperiodic, rather than oscillatory, coupling
Functional connectivity (FC) has attracted significant interest in the identification of specific circuits underlying brain (dys-)function. Classical analyses to estimate FC ( i.e ., filtering electro...
www.jneurosci.org
October 9, 2025 at 4:52 PM
This is a fascinating study dissecting the degree to which functional connectivity in EEG is driven by aperiodic activity instead of oscillations -- how robust are connectivity findings in a frequency band (theta, alpha) when oscillations are not omni-present?
www.jneurosci.org/content/earl...
www.jneurosci.org/content/earl...
Reposted by AJ Simon
Great to have @timlawn.bsky.social visiting today and presenting some really interesting findings. Cool stuff.
October 9, 2025 at 2:56 PM
Great to have @timlawn.bsky.social visiting today and presenting some really interesting findings. Cool stuff.
New preprint alert!
We used connectome-based predictive modeling in a transdiagnostic sample to identify brain network correlates of wide array of behavioral measures. We also identify where networks supporting cognition overlap with those linked to diagnostically related clinical symptomatology.
We used connectome-based predictive modeling in a transdiagnostic sample to identify brain network correlates of wide array of behavioral measures. We also identify where networks supporting cognition overlap with those linked to diagnostically related clinical symptomatology.
Transdiagnostic connectome-based predictive modeling of many behavioral phenotypes reveals brain network mediators of clinical-cognitive relationships
Connectome-based predictive modeling (CPM) applied to functional MRI connectivity data can identify brain networks that vary with behavioral measures across subjects. The prediction strength also prov...
www.biorxiv.org
October 6, 2025 at 3:42 PM
New preprint alert!
We used connectome-based predictive modeling in a transdiagnostic sample to identify brain network correlates of wide array of behavioral measures. We also identify where networks supporting cognition overlap with those linked to diagnostically related clinical symptomatology.
We used connectome-based predictive modeling in a transdiagnostic sample to identify brain network correlates of wide array of behavioral measures. We also identify where networks supporting cognition overlap with those linked to diagnostically related clinical symptomatology.
Reposted by AJ Simon
Theo Kertesz, a brilliant intern here in the B&C lab, wrote a fantastic piece about my PhD research. Read it on Medium! medium.com/p/listening-...
Listening to the Brain’s Hidden Rhythms: How Aperiodic Activity is Changing EEG and Depression…
Rates of depression have been rising steadily over the past few decades, affecting more than 280 million people worldwide (World Health…
medium.com
July 23, 2025 at 2:29 PM
Theo Kertesz, a brilliant intern here in the B&C lab, wrote a fantastic piece about my PhD research. Read it on Medium! medium.com/p/listening-...
Reposted by AJ Simon
Started a new postdoc at Yale in @brognition.bsky.social Lab with Kia Nobre! Studying adaptive cognition in humans using brain recordings—both on and in the head. New lab, new city, new chapter!
July 7, 2025 at 3:31 AM
Started a new postdoc at Yale in @brognition.bsky.social Lab with Kia Nobre! Studying adaptive cognition in humans using brain recordings—both on and in the head. New lab, new city, new chapter!
If you’re at OHBM this year, come check out my poster titled “Brain networks that mediate clinical-cognitive relationships” on Friday and Saturday at location number 1150
June 26, 2025 at 7:28 AM
If you’re at OHBM this year, come check out my poster titled “Brain networks that mediate clinical-cognitive relationships” on Friday and Saturday at location number 1150
Excited to get this collaborative paper out from my rotation with @dscheinost.bsky.social
In a new @jama.com study, @yaleschoolofmed.bsky.social's @zivbenzion.bsky.social + Alexander Simon used fMRI 🧠📷 to train machine learning models 💻 which could predict the severity of #PTSD symptoms 📈--offering a way to improve how we detect & care for the disease!
Machine learning model predicts PTSD symptom severity over time
Using functional brain imaging and machine learning, Yale researchers were able to predict PTSD symptoms 14 months after the initial traumatic event.
news.yale.edu
March 19, 2025 at 2:56 PM
Excited to get this collaborative paper out from my rotation with @dscheinost.bsky.social
Had a great time discussing network neuroscience (and skiing) at #whistlerbrain2025! Thanks for organizing @toddc.bsky.social and @anjasamardzija.bsky.social!
March 2, 2025 at 11:07 PM
Had a great time discussing network neuroscience (and skiing) at #whistlerbrain2025! Thanks for organizing @toddc.bsky.social and @anjasamardzija.bsky.social!
Reposted by AJ Simon
Last week to register! (registration closes Jan 26) #whistlerbrain
Register here: web.cvent.com/event/34b0c2...
Register here: web.cvent.com/event/34b0c2...
January 21, 2025 at 1:35 PM
Last week to register! (registration closes Jan 26) #whistlerbrain
Register here: web.cvent.com/event/34b0c2...
Register here: web.cvent.com/event/34b0c2...
Reposted by AJ Simon
“Cognitive flexibility as the shifting of brain network flows by flexible neural representations”, a solo paper by yours truly, making the case that brain activity flow shifts are essential to mental flexibility (and quite interesting too!)
Open access: www.sciencedirect.com/science/arti...
Open access: www.sciencedirect.com/science/arti...
December 3, 2024 at 6:12 PM
“Cognitive flexibility as the shifting of brain network flows by flexible neural representations”, a solo paper by yours truly, making the case that brain activity flow shifts are essential to mental flexibility (and quite interesting too!)
Open access: www.sciencedirect.com/science/arti...
Open access: www.sciencedirect.com/science/arti...