Aspirational Neuroscience
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Aspirational Neuroscience
@aspirationalneuro.bsky.social
Neuroscientists! Join Our Fortnightly Memory Encoding, Retrieval, and Emulation JC. We are a Nonprofit Community Focused on Hippocampal and LTM Decoding.
http://aspirationalneuroscience.org
Here's one of our nominations for the Aspirational Neuroscience 2025 Award! Sammons et al. at Charité–Universitätsmedizin Berlin. CA3 pyramidal neurons form a recurrent network sufficient for pattern completion. See more nominees and RSVP via our bio to join us at #SfN25.
November 15, 2025 at 3:43 AM
Here's one of our nominations for the Aspirational Neuroscience 2025 Award! Ding et al. at Baylor College of Medicine found that functional connectomics reveals a general “like-to-like” wiring rule. See more nominees and RSVP via our bio to join us at #SfN25.
November 15, 2025 at 3:41 AM
Here’s one of our nominations for the Aspirational Neuroscience 2025 Award! Uytiepo et al. at UCLA show that fear-memory engrams form through presynaptic growth of multisynaptic boutons, even without coordinated postsynaptic activation. #SfN25
November 14, 2025 at 10:13 PM
Here’s one of our nominations for the Aspirational Neuroscience 2025 Award! Ko et al. at KAIST show that systems consolidation reorganizes hippocampal engram circuitry—CA3-to-CA1 synapses cluster as memories age, driven by adult-born neurons. #SfN25
November 14, 2025 at 10:11 PM
Here's one of our nominations for the Aspirational Neuroscience 2025 Award! Chettih et al. show that each food-cache encodes a sparse hippocampal “barcode” orthogonal to place cells and reactivated on retrieval. #SfN25
November 14, 2025 at 9:40 PM
Here's one of our nominations for the Aspirational Neuroscience 2025 Award! Dorkenwald et al. map ~2k synapses among L2/3 pyramidal neurons and find a bimodal size distribution—consistent with binary strength states plus analog noise. #SfN25
November 14, 2025 at 12:11 AM
Here’s one of our nominations for the Aspirational Neuroscience 2025 Award! Wright et al. demonstrate compartmental plasticity, including apical potentiation from local coactivity (spike-independent) and basal requirements for pre- and post-coincidence (2-photon imaging). #SfN25
November 13, 2025 at 11:37 PM
Here's one of our ten nominations for the Aspirational Neuroscience 2025 Award! Abatis et al. show fear learning strengthens recurrent LA-engram synapses, forming an attractor driving recall (viral tagging + 12-cell patch-clamp). See nominees & RSVP in bio. #SfN25
November 13, 2025 at 11:35 PM
Here's one of our nominations for the Aspirational Neuroscience 2025 Award! Bittner et al. at HHMI Janelia/Stanford identified seconds-scale, non-Hebbian plasticity via dendritic plateaus that imprint CA1 place fields. Join us at #SfN25
November 13, 2025 at 5:07 AM
Aspirational Neuroscience 2025 Nominee: Tavakoli et al. (Institute of Science and Technology Austria) developed a new technique, light-microscopy-based connectomics, to fully trace all neuronal connections in brain tissue using fluorescence microscopy. #SfN2025
November 11, 2025 at 10:54 PM
Here's one of our ten nominations for the Aspirational Neuroscience 2025 Award! Lappalainen et al. fixed a recurrent network’s wiring to the Drosophila optic-lobe connectome, then task-optimized its remaining neuron/synapse parameters for optic-flow detection. #SfN2025
November 11, 2025 at 9:51 PM
Memory Decoding advances nominated for 2025 Aspirational Neuroscience Awards! aspirationalneuroscience.org/nominations-...
Join the catered SfN satellite event with Experts panel discussion: Nov. 17 @ 7pm, Hilton San Diego Bayfront room Cobalt 500 #memorydecoding #aspirationalneuroscience #SfN2025
November 11, 2025 at 9:49 PM
Reposted by Aspirational Neuroscience
#Throwback to #AspirationalNeuroscience2023: Ghosh et al. and Xiong et al. at Cold Spring Harbor Laboratory revealed how the brain establishes and maintains learned associations between sounds and actions through selective strengthening of corticostriatal synapses.

#SfN25
November 9, 2025 at 6:35 PM
Reposted by Aspirational Neuroscience
Here's one of our ten nominations for the Aspirational Neuroscience 2025 Award! Lappalainen et al. fixed a recurrent network’s wiring to the Drosophila optic-lobe connectome, then task-optimized its remaining neuron/synapse parameters for optic-flow detection.

#SfN2025
November 9, 2025 at 7:06 PM
Reposted by Aspirational Neuroscience
1 week until our satellite event at SFN SD! RSVP at the link in our bio.
November 10, 2025 at 3:53 PM
Reposted by Aspirational Neuroscience
#Throwback to #AspirationalNeuroscience2023: here's one of our six winners from Aspirational Neuroscience 2023! J-H. Choi et al. & D. Choi et al. at the Korea Advanced Institute of Science and Technology provided insights into encoding memories at a structural & molecular level.

#SfN2025
November 10, 2025 at 5:29 PM
Reposted by Aspirational Neuroscience
Here's one of our ten nominations for the Aspirational Neuroscience 2025 Award! Tavakoli et al. at the Institute of Science and Technology Austria developed a new technique, light-microscopy-based connectomics, to fully trace all neuronal connections in brain tissue using fluorescence microscopy.
November 10, 2025 at 5:54 PM
Reposted by Aspirational Neuroscience
2 weeks until our satellite event at SFN SD! RSVP at link in bio.
November 4, 2025 at 4:27 AM
Reposted by Aspirational Neuroscience
Remembering past winners and nominations for the Aspirational Neuroscience Awards!
November 5, 2025 at 1:00 AM
Reposted by Aspirational Neuroscience
Memory Decoding advances nominated for 2025 Aspirational Neuroscience Awards!
November 5, 2025 at 10:07 PM
Reposted by Aspirational Neuroscience
The Aspirational Neuroscience Awards exist to honor and highlight groundbreaking scientific to research into how learning and memory are physically encoded in the brain. Here is one of the 2025 nominations:

A Drosophila computational brain model reveals sensorimotor processing
Author(s): Shiu et al
November 6, 2025 at 2:21 PM
Journal club TODAY at 3 pm US Pacific Time: Functional Connectomics Reveals General Wiring Rule in Mouse Visual Cortex -- join at carboncopies.org/aspirational... #neuroscience #memorydecoding #aspirationalneuroscience #connectomics #mouse
October 21, 2025 at 5:23 PM
Join us TODAY at 3 pm US Pacific time for "Connectomic traces of Hebbian plasticity in the entorhinal-hippocampal system" at carboncopies.org/aspirational... #memorydecoding #aspirationalneuroscience #hippocampal #plasticity #connectome
October 7, 2025 at 8:41 PM
Join us TODAY at carboncopies.org/aspirational... for a memory decoding journal club about plasticity rules in dendritic compartments presented by Dr. Kenneth Hayworth #memory #decoding #neuroscience #plasticity #dendrites
September 23, 2025 at 7:57 PM
Join our Memory Decoding journal club to discuss the paper "A combinatorial neural code for long-term motor memory" - on Tue., Sep. 9 at 3 pm US Pacific Time at carboncopies.org/aspirational... #memory #decoding #neuroscience #LTM #motor
September 8, 2025 at 3:52 PM