Anthony Costa
banner
anthonybcosta.bsky.social
Anthony Costa
@anthonybcosta.bsky.social
Digital Biology @NVIDIA
I'm hiring! Are you a technical, senior product leader passionate about driving the next generation of biomolecular simulation software? Then come and join our team! Apply here: bit.ly/pm-bionemo-s...
Senior Product Manager, BioNeMo Simulation
NVIDIA seeks a Product Manager to lead our work in molecular dynamics (MD) and AI-accelerated simulation projects for life sciences. We are interested in finding global authorities and leaders at the ...
bit.ly
June 2, 2025 at 2:46 PM
Just released BioNeMo Framework v2.6! Check it out here: github.com/NVIDIA/bione...

Particularly notable include support for AMPLIFY, with a 70% speed over the existing xformers-based attention backend (+ validation), alpha LoRA ESM, and a ton of fixes and improvements.
Release NVIDIA BioNeMo Framework v2.6 · NVIDIA/bionemo-framework
New Features Adds support for AMPLIFY doi:10.1101/2024.09.23.614603 pre-training and inference, offering a 70% speedup over the xformers-based attention backend with similar final perplexity value...
github.com
May 10, 2025 at 2:33 PM
Still empty. Employees seem to be having a great time.
May 4, 2025 at 8:45 PM
Check out new work from NVIDIA Genomics and Genentech: transcriptome-guided genomic alignment with transformer-based splice junction scoring, delivering SOTA in splice junction detection, indel identification, and resolving complex splicing patterns www.biorxiv.org/content/10.1...
DeepSAP: Improved RNA-Seq Alignment by Integrating Transcriptome Guidance with Transformer-Based Splice Junction Scoring
Advancements in high-throughput sequencing have revolutionized the field of transcriptomics, pro-viding unprecedented insights into gene expression, splicing events, and fusions. Despite these advance...
www.biorxiv.org
April 30, 2025 at 2:32 PM
Goodbye Singapore! Thanks for everything.
April 28, 2025 at 12:41 PM
Congratulations to Peter Holderrieth @msalbergo.bsky.social and Tommi Jaakkola for winning the best paper award for their work entitled "LEAPS: A discrete neural sampler via locally equivariant networks" at this year's Frontiers in Probabilistic Inference workshop #ICLR2025!
April 28, 2025 at 4:53 AM
Finally reached the limit of capability for my M1 Pro MacBook: Lightroom editing of 17 stitched 60Mp L compressed RAW.
April 28, 2025 at 4:13 AM
Beautiful night to gather the techbio community in Singapore! #ICLR2025 @recursionpharma.bsky.social @valenceai.bsky.social
April 25, 2025 at 1:55 PM
Heading to 🇸🇬 for #ICLR2025! Amazing work from our NVIDIA digital biology teams the whole week, plus a great opportunity to visit our local colleagues. Come say hi!
April 20, 2025 at 4:02 PM
One of my favorite flight experiences descending into Newark right now. Smooth as silk air, snow up at 1K ft flying by the window lit up by our approach lights.
April 12, 2025 at 3:23 AM
Walking around Rockland today.
March 28, 2025 at 1:29 AM
Reposted by Anthony Costa
“It tackles the big next step after AlphaFold 3,” Luca Naef, VantAI’s CTO, told me.

I talked with CEO Zach Carpenter, @lucanaef.bsky.social Luca, and @mmbronstein.bsky.social on VantAI's most substantive update since its 2019 start.

My exclusive for @endpts.com: endpts.com/exclusive-va...
Exclusive: Roivant-backed VantAI debuts AI model Neo-1, taking ‘the big next step’ after AlphaFold 3
VantAI unveils Neo-1, an AI model that simultaneously predicts biomolecule structures and generates new molecular glues, claiming advancement beyond AlphaFold 3's capabilities.
endpts.com
March 21, 2025 at 12:12 PM
I finally did it, a picture with the great @mmbronstein.bsky.social!! Enjoying the talk so far at #GTC2025, “Advancing Molecular Design with Deep Learning”.
March 19, 2025 at 5:15 PM
Reposted by Anthony Costa
New paper (and #ICLR2025 Oral :)):
ProtComposer: Compositional Protein Structure Generation with 3D Ellipsoids arxiv.org/abs/2503.05025

Condition on your 3D layout (of ellipsoids) to generate proteins like this or to get better designability/diversity/novelty tradeoffs.
1/6
March 10, 2025 at 7:51 PM
Reposted by Anthony Costa
The Evo 2 authors join us tomorrow in the reading group to discuss their paper: "Genome modeling and design across all domains of life with Evo 2" www.biorxiv.org/content/10.1...

Join on zoom (Monday) at 9am PT / 12pm ET / 6pm CET: www.biorxiv.org/content/10.1...
March 9, 2025 at 5:14 PM
I prefer more light later in the day and would therefore like to see DST become permanent. But mostly I just want to stop the changes.
March 9, 2025 at 11:40 AM
By my count, I have four different Nature accounts, and there is absolutely no way to link them all up.
February 19, 2025 at 3:25 PM
@lilasciences.bsky.social 3rd follow! I’ll take it.
December 5, 2024 at 2:32 AM
Reposted by Anthony Costa
We at LilaSciences are excited to come out of stealth!

Join us at #NeurIPS2024 for a happy hour co-hosted with Nvidia, featuring a discussion on AI in science with Max Welling and Chris Bishop.

If you’ll be at NeurIPS this year, we’d love to see you!

RSVP here: lu.ma/nt1c4vf4
Toward Scientific Superintelligence with Lila Sciences and NVIDIA · Luma
Join Lila Sciences at NeurIPS at an exclusive event cohosted with NVIDIA to explore the transformative potential of AI in scientific discovery. Featuring a…
lu.ma
December 4, 2024 at 3:32 PM
@geraldundone.bsky.social happy you’re here!
December 3, 2024 at 12:09 PM
Reposted by Anthony Costa
Three BioML starter packs now!

Pack 1: go.bsky.app/2VWBcCd
Pack 2: go.bsky.app/Bw84Hmc
Pack 3: go.bsky.app/NAKYUok

DM if you want to be included (or nominate people who should be!)
December 3, 2024 at 3:27 AM
If @nathanbenaich.bsky.social really digs in here I might really be able to make a majority platform switch. No pressure.
December 2, 2024 at 5:14 AM
So many great collaborators, friends, colleagues, and #techbio leaders will be here. Unfortunately I’m going to miss the conference this year, but come find all my awesome colleagues!
December 2, 2024 at 4:46 AM
I feel like I’ve put together a pretty informative network of folks in AI/ML for chem, bio, genomics, materials, physics, and science generally, at least on par with what I had on Twitter. Thanks to all of you for doing the hard work up front. Don’t understand the vibe yet, but it feels exciting!
December 2, 2024 at 4:21 AM