Andy Purkiss
@andypurk.bsky.social
X-ray crystallographer and structural biologist at the Francis Crick Institute. Cats not dogs. Also interested in railways, Sci-Fi and Star Trek (amongst other things). Type 1 Diabetic
therapist: pick your battles
me: okay helm’s deep
me: okay helm’s deep
November 23, 2025 at 2:27 AM
Reposted by Andy Purkiss
A tiny bit of shameless self-promotion because the gifting season is creeping up on us. If you’re after something delicious, handcrafted, and ethical, my chocolate boxes, bars, and treats make really lovely gifts. Treat yourself, treat someone else, or both, I won’t judge! Reshares appreciated! 🍫✨
November 22, 2025 at 6:51 PM
A tiny bit of shameless self-promotion because the gifting season is creeping up on us. If you’re after something delicious, handcrafted, and ethical, my chocolate boxes, bars, and treats make really lovely gifts. Treat yourself, treat someone else, or both, I won’t judge! Reshares appreciated! 🍫✨
Reposted by Andy Purkiss
During this cloudflare outage, let me supply you with this wisdom of the ages: “single point of failure” can be sung to the tune of “all the single ladies”
November 18, 2025 at 1:43 PM
During this cloudflare outage, let me supply you with this wisdom of the ages: “single point of failure” can be sung to the tune of “all the single ladies”
The annual check that it is cheaper to spend an extra night in Nottingham than travel on the morning for #CCP4SW in January shows that it is still the case. The 11:00 start means expensive travel on the day and a Super Off-Peak return is cheaper than using peak time Advance tickets! #EMR
November 17, 2025 at 3:30 PM
Post your favourite Star Trek character. Wrong answers only.
November 15, 2025 at 2:07 PM
Post your favourite Star Trek character. Wrong answers only.
Amongst many others: Aladdin
November 15, 2025 at 4:09 AM
Amongst many others: Aladdin
Reposted by Andy Purkiss
Excited to share our discovery of the RAD51 filament cap, built by a newly identified RAD51 paralog complex 🔬🧬
‼️ Excited to share our new paper out now in @science.org ‼️
We describe a new tetrameric RAD51 paralog complex – XRCC3-RAD51C-RAD51D-XRCC2 – which caps the end of RAD51 filaments.
Link: www.science.org/doi/epdf/10....
Thread ⬇️ (1/8)
We describe a new tetrameric RAD51 paralog complex – XRCC3-RAD51C-RAD51D-XRCC2 – which caps the end of RAD51 filaments.
Link: www.science.org/doi/epdf/10....
Thread ⬇️ (1/8)
November 7, 2025 at 10:22 AM
Excited to share our discovery of the RAD51 filament cap, built by a newly identified RAD51 paralog complex 🔬🧬
A spontaneous laugh out loud at Phil Ellis' "it's the other end" response when talking about a pig's corkscrew penis in tonight's #Taskmaster
October 30, 2025 at 9:45 PM
A spontaneous laugh out loud at Phil Ellis' "it's the other end" response when talking about a pig's corkscrew penis in tonight's #Taskmaster
Reposted by Andy Purkiss
Heyyyyy MEMBRANE protein people! We are running our (fairly rare) membrane screen in November, so get your reservations in! 🦠
Get a crystal this November with our high-throughput crystallization screening service!
This month, we are running both SOLUBLE and MEMBRANE crystallization screens. 🔮
Details ⬇️⬇️⬇️
This month, we are running both SOLUBLE and MEMBRANE crystallization screens. 🔮
Details ⬇️⬇️⬇️
October 29, 2025 at 8:21 PM
Heyyyyy MEMBRANE protein people! We are running our (fairly rare) membrane screen in November, so get your reservations in! 🦠
Ponyo.
With an honourable mention for Star Trek The Motion Picture!
With an honourable mention for Star Trek The Motion Picture!
October 23, 2025 at 8:34 PM
Ponyo.
With an honourable mention for Star Trek The Motion Picture!
With an honourable mention for Star Trek The Motion Picture!
Permission to Land by The Darkness (amongst many others)
Name you fav Debut Album.
October 23, 2025 at 1:16 AM
Permission to Land by The Darkness (amongst many others)
Share someone who looks stylish in a hat.
October 18, 2025 at 9:01 PM
Share someone who looks stylish in a hat.
Reply with an image you can hear 💚
October 15, 2025 at 9:12 PM
Reply with an image you can hear 💚
October 13, 2025 at 7:38 PM
The Ladykillers (the 1955 version).
Honourable mentions for Hot Fuzz (2007) and Murder on the Orient Express (1974) especially for the train departure sequence.
Honourable mentions for Hot Fuzz (2007) and Murder on the Orient Express (1974) especially for the train departure sequence.
Name your Fav Non-American Film.
October 9, 2025 at 6:37 PM
The Ladykillers (the 1955 version).
Honourable mentions for Hot Fuzz (2007) and Murder on the Orient Express (1974) especially for the train departure sequence.
Honourable mentions for Hot Fuzz (2007) and Murder on the Orient Express (1974) especially for the train departure sequence.
October 6, 2025 at 7:41 PM
"And I have nothing to declare except Rebo's genius either! Ha ha ha! Zooty zoot zoot zoot."
Name a Quote from a TV Show.
October 1, 2025 at 8:59 PM
"And I have nothing to declare except Rebo's genius either! Ha ha ha! Zooty zoot zoot zoot."
New network cable installed, speed jumped from the old cat 5 cable max of 1 Gbps to 2.2 Gbps which is close to the max which the PC's interface (2.5 Gbps) and new #CommunityFibre connection can do.
Now need to find a good route for it from the router to the desk but plenty of slack to play with.
Now need to find a good route for it from the router to the desk but plenty of slack to play with.
October 1, 2025 at 8:14 PM
New network cable installed, speed jumped from the old cat 5 cable max of 1 Gbps to 2.2 Gbps which is close to the max which the PC's interface (2.5 Gbps) and new #CommunityFibre connection can do.
Now need to find a good route for it from the router to the desk but plenty of slack to play with.
Now need to find a good route for it from the router to the desk but plenty of slack to play with.