Andrea Morandi
@andreamorandi.bsky.social
Associate Professor of Biochemistry and PI of the Tumour Biochemistry Lab @UNIFI | Head of the Breast Unit Translational Lab @AOUC
https://www.sbsc.unifi.it/vp-326-gruppo-morandi.html
https://www.ncbi.nlm.nih.gov/myncbi/1JM7xFr2A8y56/bibliography/public
https://www.sbsc.unifi.it/vp-326-gruppo-morandi.html
https://www.ncbi.nlm.nih.gov/myncbi/1JM7xFr2A8y56/bibliography/public
📣 It’s been a productive few days for our group!
💡Our new paper in 𝘊𝘦𝘭𝘭 𝘋𝘦𝘢𝘵𝘩 & 𝘋𝘪𝘴𝘦𝘢𝘴𝘦 shows that lead nitrate drives NRF2-dependent metabolic reprogramming and proliferation in hepatocytes.
With Università di Cagliari & Università di Torino, funded by MUR#PRIN2022.
🔗 www.nature.com/articles/s41...
💡Our new paper in 𝘊𝘦𝘭𝘭 𝘋𝘦𝘢𝘵𝘩 & 𝘋𝘪𝘴𝘦𝘢𝘴𝘦 shows that lead nitrate drives NRF2-dependent metabolic reprogramming and proliferation in hepatocytes.
With Università di Cagliari & Università di Torino, funded by MUR#PRIN2022.
🔗 www.nature.com/articles/s41...
Lead induces cell-autonomous proliferation and metabolic reprogramming of hepatocytes - Cell Death & Disease
Cell Death & Disease - Lead induces cell-autonomous proliferation and metabolic reprogramming of hepatocytes
www.nature.com
November 11, 2025 at 10:48 AM
📣 It’s been a productive few days for our group!
💡Our new paper in 𝘊𝘦𝘭𝘭 𝘋𝘦𝘢𝘵𝘩 & 𝘋𝘪𝘴𝘦𝘢𝘴𝘦 shows that lead nitrate drives NRF2-dependent metabolic reprogramming and proliferation in hepatocytes.
With Università di Cagliari & Università di Torino, funded by MUR#PRIN2022.
🔗 www.nature.com/articles/s41...
💡Our new paper in 𝘊𝘦𝘭𝘭 𝘋𝘦𝘢𝘵𝘩 & 𝘋𝘪𝘴𝘦𝘢𝘴𝘦 shows that lead nitrate drives NRF2-dependent metabolic reprogramming and proliferation in hepatocytes.
With Università di Cagliari & Università di Torino, funded by MUR#PRIN2022.
🔗 www.nature.com/articles/s41...
Here is my weekly selection of #anticancer #therapy and #metabolic #reprogramming! Super interesting papers this issue (including our last study😂🤩😛) Enjoy! 🙏 @biomednews.bsky.social biomed.news/bims-meract/...
a man says i need you to pick one
ALT: a man says i need you to pick one
media.tenor.com
November 9, 2025 at 8:23 AM
Here is my weekly selection of #anticancer #therapy and #metabolic #reprogramming! Super interesting papers this issue (including our last study😂🤩😛) Enjoy! 🙏 @biomednews.bsky.social biomed.news/bims-meract/...
🚨 Our new paper is now out in 𝘊𝘢𝘯𝘤𝘦𝘳 𝘙𝘦𝘴𝘦𝘢𝘳𝘤𝘩!
ESR1 mutations in ER⁺ breast cancer rewire lipid metabolism, creating a ferroptosis vulnerability 🔬
ACSL4 is a key biomarker & combo with SERDs offers a new strategy.
👏 Congrats to the whole #TBTlab & collaborators!
aacrjournals.org/cancerres/ar...
ESR1 mutations in ER⁺ breast cancer rewire lipid metabolism, creating a ferroptosis vulnerability 🔬
ACSL4 is a key biomarker & combo with SERDs offers a new strategy.
👏 Congrats to the whole #TBTlab & collaborators!
aacrjournals.org/cancerres/ar...
ESR1 Activating Mutations Confer Metabolic Vulnerabilities in ER+ Breast Cancer
Abstract. Endocrine therapy (ET) is the standard of care for estrogen receptor-positive (ER+) breast cancer. Point mutations in the ligand-binding domain of the gene encoding the estrogen receptor (ES...
aacrjournals.org
November 7, 2025 at 8:20 PM
🚨 Our new paper is now out in 𝘊𝘢𝘯𝘤𝘦𝘳 𝘙𝘦𝘴𝘦𝘢𝘳𝘤𝘩!
ESR1 mutations in ER⁺ breast cancer rewire lipid metabolism, creating a ferroptosis vulnerability 🔬
ACSL4 is a key biomarker & combo with SERDs offers a new strategy.
👏 Congrats to the whole #TBTlab & collaborators!
aacrjournals.org/cancerres/ar...
ESR1 mutations in ER⁺ breast cancer rewire lipid metabolism, creating a ferroptosis vulnerability 🔬
ACSL4 is a key biomarker & combo with SERDs offers a new strategy.
👏 Congrats to the whole #TBTlab & collaborators!
aacrjournals.org/cancerres/ar...
Here is my weekly selection of #anticancer #therapy and #metabolic #reprogramming! Many interesting paper today 🤩 Enjoy and feedback! 🙏 @biomednews.bsky.social biomed.news/bims-meract/...
a man is reading a book in front of a pumpkin and candle
ALT: a man is reading a book in front of a pumpkin and candle
media.tenor.com
November 2, 2025 at 4:24 PM
Here is my weekly selection of #anticancer #therapy and #metabolic #reprogramming! Many interesting paper today 🤩 Enjoy and feedback! 🙏 @biomednews.bsky.social biomed.news/bims-meract/...
Thanks Federica and congratulations once again! 🥳
Back from the 37th AICC International Meeting in Florence 🇮🇹! Honored to present my work and receive the Best Oral Presentation Award 🏆 Huge thanks to the organizers, especially @andreamorandi.bsky.social and his team, for their support and for such an inspiring event! 🤩
October 30, 2025 at 8:03 PM
Thanks Federica and congratulations once again! 🥳
Here a selection of last week studies on #anticancer #therapy and #metabolic #reprogramming. Big thanks @biomednews.bsky.social for presorting them.
V good studies in this issue, have a look
biomed.news/bims-meract/...
V good studies in this issue, have a look
biomed.news/bims-meract/...
a man with glasses and a beard is making a perfect choice face
ALT: a man with glasses and a beard is making a perfect choice face
media.tenor.com
October 26, 2025 at 10:27 PM
Here a selection of last week studies on #anticancer #therapy and #metabolic #reprogramming. Big thanks @biomednews.bsky.social for presorting them.
V good studies in this issue, have a look
biomed.news/bims-meract/...
V good studies in this issue, have a look
biomed.news/bims-meract/...
Busy weekdays and busy weekends. A bit late but please find two selection lists of #anticancer #therapy and #metanolism. Hope you find some useful studies. Thanks @biomednews.bsky.social
(1) biomed.news/bims-meract/...
(2) biomed.news/bims-meract/...
(1) biomed.news/bims-meract/...
(2) biomed.news/bims-meract/...
the white rabbit from alice in wonderland is running with a pocket watch in his mouth .
ALT: the white rabbit from alice in wonderland is running with a pocket watch in his mouth .
media.tenor.com
October 12, 2025 at 9:12 PM
Busy weekdays and busy weekends. A bit late but please find two selection lists of #anticancer #therapy and #metanolism. Hope you find some useful studies. Thanks @biomednews.bsky.social
(1) biomed.news/bims-meract/...
(2) biomed.news/bims-meract/...
(1) biomed.news/bims-meract/...
(2) biomed.news/bims-meract/...
Here’s my weekly selection of #anticancer #therapy and #metabolic #reprogramming. From now on, I’ll focus on papers in journals with solid peer-review — a personal choice and point of view. 🙏 @biomednews.bsky.social
biomed.news/bims-meract/...
biomed.news/bims-meract/...
a black and white photo of a person reading a book called aventura
ALT: a black and white photo of a person reading a book called aventura
media.tenor.com
September 28, 2025 at 9:00 AM
Here’s my weekly selection of #anticancer #therapy and #metabolic #reprogramming. From now on, I’ll focus on papers in journals with solid peer-review — a personal choice and point of view. 🙏 @biomednews.bsky.social
biomed.news/bims-meract/...
biomed.news/bims-meract/...
Here is my weekly selection on #anticancer #therapy and #metabolic #reprogramming. Hope you enjoy! biomed.news/2025-09-14 🙏 @biomednews.bsky.social
a cartoon of snoopy reading a book while woodstock looks on
ALT: a cartoon of snoopy reading a book while woodstock looks on
media.tenor.com
September 14, 2025 at 1:43 PM
Here is my weekly selection on #anticancer #therapy and #metabolic #reprogramming. Hope you enjoy! biomed.news/2025-09-14 🙏 @biomednews.bsky.social
Here is my weekly selection of #anticancer #therapy and #metabolism #reprogramming. Enjoy! biomed.news/bims-meract/...
a woman is sitting on a couch reading a book titled pieces of our soul
ALT: a woman is sitting on a couch reading a book titled pieces of our soul
media.tenor.com
September 9, 2025 at 7:27 AM
Here is my weekly selection of #anticancer #therapy and #metabolism #reprogramming. Enjoy! biomed.news/bims-meract/...
Another week has gone 😨! Here is my weekly selection for #anticancer #metabolic #reprogramming! Enjoy
a man in a suit and tie is asking if he read it
ALT: a man in a suit and tie is asking if he read it
media.tenor.com
August 3, 2025 at 7:22 PM
Another week has gone 😨! Here is my weekly selection for #anticancer #metabolic #reprogramming! Enjoy
Reposted by Andrea Morandi
Good Sunday all. A beautiful selection of papers in #cancermetabolism and #mitochondrialbiology is ready for you here: biomed.news/bims-camemi/... @biomednews.bsky.social #keepreading
"If your eyes are blinded with your worries, you cannot see the beauty of the sunset." - Jiddu Krishnamurti
"If your eyes are blinded with your worries, you cannot see the beauty of the sunset." - Jiddu Krishnamurti
an illustration of a bird holding a stack of books with reading time written above it
ALT: an illustration of a bird holding a stack of books with reading time written above it
media.tenor.com
July 27, 2025 at 4:34 AM
Good Sunday all. A beautiful selection of papers in #cancermetabolism and #mitochondrialbiology is ready for you here: biomed.news/bims-camemi/... @biomednews.bsky.social #keepreading
"If your eyes are blinded with your worries, you cannot see the beauty of the sunset." - Jiddu Krishnamurti
"If your eyes are blinded with your worries, you cannot see the beauty of the sunset." - Jiddu Krishnamurti
Here is my weekly selection of #anticancer #therapy and #metabolic #reprogramming. 🙏 @biomednews.bsky.social Enjoy and share 😊 biomed.news/bims-meract/...
a penguin is floating in the water with the words summer fun
ALT: a penguin is floating in the water with the words summer fun
media.tenor.com
July 27, 2025 at 11:45 AM
Here is my weekly selection of #anticancer #therapy and #metabolic #reprogramming. 🙏 @biomednews.bsky.social Enjoy and share 😊 biomed.news/bims-meract/...
Here is my weekly selection on #cancer #metabolism and #therapy #response and #resistance, enjoy! biomed.news/bims-meract/...
jerry from tom and jerry is reading a book while laying on a lounge chair
ALT: jerry from tom and jerry is reading a book while laying on a lounge chair
media.tenor.com
July 15, 2025 at 5:09 PM
Here is my weekly selection on #cancer #metabolism and #therapy #response and #resistance, enjoy! biomed.news/bims-meract/...
New weekly selection out! #anticancer #therapy #resistance #metabolism
Enjoy! @biomednews.bsky.social
biomed.news/bims-meract/...
Enjoy! @biomednews.bsky.social
biomed.news/bims-meract/...
a group of young men are sitting together and one of them is wearing a panda movie shirt
ALT: a group of young men are sitting together and one of them is wearing a panda movie shirt
media.tenor.com
July 8, 2025 at 8:59 AM
New weekly selection out! #anticancer #therapy #resistance #metabolism
Enjoy! @biomednews.bsky.social
biomed.news/bims-meract/...
Enjoy! @biomednews.bsky.social
biomed.news/bims-meract/...
Reposted by Andrea Morandi
You might be interested to know about an upcoming EACR-sponsored meeting organised by the Italian Cancer Society, an affiliated National Society of the EACR.
65th Annual Meeting of the Italian Cancer Society
📅 03-05 Dec 2025
🌍 Turin, Italy
sic2025.cancerologia.it
65th Annual Meeting of the Italian Cancer Society
📅 03-05 Dec 2025
🌍 Turin, Italy
sic2025.cancerologia.it
June 30, 2025 at 9:21 AM
You might be interested to know about an upcoming EACR-sponsored meeting organised by the Italian Cancer Society, an affiliated National Society of the EACR.
65th Annual Meeting of the Italian Cancer Society
📅 03-05 Dec 2025
🌍 Turin, Italy
sic2025.cancerologia.it
65th Annual Meeting of the Italian Cancer Society
📅 03-05 Dec 2025
🌍 Turin, Italy
sic2025.cancerologia.it
Here is my weekly selection for #anticancer #tgerapy and #metabolic #reprograming. Enjoy!
biomed.news/bims-meract/...
🙏 @biomednews.bsky.social
biomed.news/bims-meract/...
🙏 @biomednews.bsky.social
a man is sitting at a desk reading a book .
ALT: a man is sitting at a desk reading a book .
media.tenor.com
June 30, 2025 at 10:42 AM
Here is my weekly selection for #anticancer #tgerapy and #metabolic #reprograming. Enjoy!
biomed.news/bims-meract/...
🙏 @biomednews.bsky.social
biomed.news/bims-meract/...
🙏 @biomednews.bsky.social
📣New study w/ Dr. Longo’s team @UNITO shows MRI-CEST tumor pH imaging can differentiate metastatic from non-metastatic breast tumors via acidosis + spatial heterogeneity 🧪 A big step toward metabolic markers of malignancy!
breast-cancer-research.biomedcentral.com/articles/10....
breast-cancer-research.biomedcentral.com/articles/10....
In vivo imaging of the spatial heterogeneity of intratumoral acidosis (pH) as a marker of the metastatic phenotype in breast cancer - Breast Cancer Research
Background Metabolic alterations, including acidosis in the tumor microenvironment, have been extensively linked to more aggressive phenotypes and increased therapy resistance. However, current imagin...
breast-cancer-research.biomedcentral.com
June 27, 2025 at 11:35 AM
📣New study w/ Dr. Longo’s team @UNITO shows MRI-CEST tumor pH imaging can differentiate metastatic from non-metastatic breast tumors via acidosis + spatial heterogeneity 🧪 A big step toward metabolic markers of malignancy!
breast-cancer-research.biomedcentral.com/articles/10....
breast-cancer-research.biomedcentral.com/articles/10....
Good morning and good weekend everyone! Here’s my weekly selection of #anticancer #therapy and #metabolic #reprogramming, enjoy!
biomed.news/bims-meract/...
biomed.news/bims-meract/...
a record player sits on a beach next to a purse
ALT: a record player sits on a beach next to a purse
media.tenor.com
June 22, 2025 at 5:23 AM
Good morning and good weekend everyone! Here’s my weekly selection of #anticancer #therapy and #metabolic #reprogramming, enjoy!
biomed.news/bims-meract/...
biomed.news/bims-meract/...
Great to take part in the Early Career Researcher Speed Networking! Enjoyed sharing my experience as junior PI and future research plans and the hurdles ahead. #ECR #ResearchLife #EACR2025
Our early career and student participants are speed networking this afternoon! Fantastic to see all the new connections being made at #EACR2025
June 18, 2025 at 4:34 PM
Great to take part in the Early Career Researcher Speed Networking! Enjoyed sharing my experience as junior PI and future research plans and the hurdles ahead. #ECR #ResearchLife #EACR2025
Great atmosphere at the symposium: interactive, engaging, and a fantastic space for young researchers to join the discussion. Truly a pleasure to be part of it. Hope to see this session back in future editions! @helloeacr.bsky.social #EACR2025
Today’s Early Career Symposium started with the excellent presentations of:
Andrea Morandi
Rita Acúrcio
Silvia Brugiapaglia
Arianna Baggiolini
Stay tuned 🤩
#EACR2025
@helloeacr.bsky.social
Andrea Morandi
Rita Acúrcio
Silvia Brugiapaglia
Arianna Baggiolini
Stay tuned 🤩
#EACR2025
@helloeacr.bsky.social
June 16, 2025 at 10:39 AM
Great atmosphere at the symposium: interactive, engaging, and a fantastic space for young researchers to join the discussion. Truly a pleasure to be part of it. Hope to see this session back in future editions! @helloeacr.bsky.social #EACR2025
Weekly selection of #anticancer #therapy and #metabolic #reprogramming. Enjoy.
biomed.news/bims-meract/... bims-meract 2025-06-15 papers
🙏 @biomednews.bsky.social
biomed.news/bims-meract/... bims-meract 2025-06-15 papers
🙏 @biomednews.bsky.social
a man with glasses and a xl shirt says a very good pick
ALT: a man with glasses and a xl shirt says a very good pick
media.tenor.com
June 16, 2025 at 5:31 AM
Weekly selection of #anticancer #therapy and #metabolic #reprogramming. Enjoy.
biomed.news/bims-meract/... bims-meract 2025-06-15 papers
🙏 @biomednews.bsky.social
biomed.news/bims-meract/... bims-meract 2025-06-15 papers
🙏 @biomednews.bsky.social
Reposted by Andrea Morandi
We're excited to introduce you to our Congress Correspondents who will be sharing real-time highlights from #EACR2025
Follow them ahead of the Congress starting on 16 June:
👉 @peioazcoaga.bsky.social
👉 @simofu.bsky.social
👉 @vrscience.bsky.social
👉 @luisa86ferreira.bsky.social
👉 @isaqg.bsky.social
Follow them ahead of the Congress starting on 16 June:
👉 @peioazcoaga.bsky.social
👉 @simofu.bsky.social
👉 @vrscience.bsky.social
👉 @luisa86ferreira.bsky.social
👉 @isaqg.bsky.social
June 13, 2025 at 7:01 AM
We're excited to introduce you to our Congress Correspondents who will be sharing real-time highlights from #EACR2025
Follow them ahead of the Congress starting on 16 June:
👉 @peioazcoaga.bsky.social
👉 @simofu.bsky.social
👉 @vrscience.bsky.social
👉 @luisa86ferreira.bsky.social
👉 @isaqg.bsky.social
Follow them ahead of the Congress starting on 16 June:
👉 @peioazcoaga.bsky.social
👉 @simofu.bsky.social
👉 @vrscience.bsky.social
👉 @luisa86ferreira.bsky.social
👉 @isaqg.bsky.social
Here is my weekly selection of #anticancer #therapy and #metabolic #reprogramming!
Enjoy!
biomed.news/bims-meract/...
Enjoy!
biomed.news/bims-meract/...
a cartoon of jerry reading a book while laying on a beach chair
ALT: a cartoon of jerry reading a book while laying on a beach chair
media.tenor.com
June 8, 2025 at 2:23 PM
Here is my weekly selection of #anticancer #therapy and #metabolic #reprogramming!
Enjoy!
biomed.news/bims-meract/...
Enjoy!
biomed.news/bims-meract/...
Good Sunday everybody! Here is my weekly selection of #anticancer #therapy and #metabolism. Enjoy! biomed.news/bims-meract/...
a cartoon character is sitting in a red chair reading a book .
ALT: a cartoon character is sitting in a red chair reading a book .
media.tenor.com
May 25, 2025 at 5:54 AM
Good Sunday everybody! Here is my weekly selection of #anticancer #therapy and #metabolism. Enjoy! biomed.news/bims-meract/...