The Analytical Scientist
banner
analyticalsci.bsky.social
The Analytical Scientist
@analyticalsci.bsky.social
Reporting on the people, technology and innovations shaping #AnalyticalScience #MassSpec 🔬

https://theanalyticalscientist.com/
We’re at SLAS 2026! 🔬

Excited to connect with the life sciences community and explore the latest innovations in lab automation, screening, and drug discovery.

See you there!
#SLAS2026 #LifeSciences #DrugDiscovery #LabAutomation
February 10, 2026 at 1:01 PM
Cells that glow when proteins change 🔬✨

Rice University researchers have created a living sensor that tracks post-translational modifications in real time - even inside tumors.

We spoke with Prof. Han Xiao about what this means for drug discovery and cancer research 👉 https://ow.ly/B0mH50XWASM
Living Sensor Illuminates Epigenetic Changes Inside Cells
A genetically encoded sensor platform allows researchers to watch PTM dynamics inside cells and tumors – opening new paths in drug discovery
ow.ly
February 5, 2026 at 11:40 AM
Attending conferences this year?

Explore a curated list of analytical science conferences to stay connected with the latest research, technologies, and industry leaders.

👉 Browse the conference calendar:
https://ow.ly/rs5k50Y4amq

#AnalyticalChemistry #ConferenceLife #ResearchCommunity
February 4, 2026 at 11:05 AM
What does success look like in the age of AI?

In Part Two of Tomorrow’s Science Leaders, Power List honorees discuss redefining impact, leadership beyond metrics, and why trust, listening, and individuality matter more than ever.

🔗 Read more: https://ow.ly/JHYg50XSZEs
#WomenInScience
February 2, 2026 at 2:50 PM
A new method unites proteomics and genomics in one experiment.

Román González Prieto explains how PLAMseq enables antibody-free, systematic study of chromatin-associated proteins.

👉 Read more: https://ow.ly/OiI550Y07W9
#Epigenetics #Genomics
January 30, 2026 at 3:30 PM
"Riva isn’t optional.”

Chiara Cordero explains why the return of the ISCC and GC×GC Symposia matters so deeply to separation science, and how Riva continues to shape careers, ideas, and innovation.

👉 Read more: https://ow.ly/6yHQ50Y08lf
#Chromatography #SeparationScience
January 29, 2026 at 2:25 PM
GLP-1 success is fueling peptide innovation - and raising the bar for analytics.

New molecules. New delivery strategies. New analytical challenges.

👉 Read more: https://ow.ly/UGk650Y4a0h

#GLP1 #Peptides #PharmaTech
January 27, 2026 at 1:45 PM
Is sample preparation still an art, or is it finally becoming a science? 🔬

Marcela Segundo, Marcello Locatelli & Stig Pedersen-Bjergaard discuss automation, sustainability, and the future of sample prep.

Read more 👉
https://ow.ly/8Flf50XWAuz
#SamplePreparation
January 23, 2026 at 11:10 AM
Can handheld spectroscopy reveal disease resistance in forests?

Researchers used portable NIR + chemometrics to identify chemical signatures of resistance in loblolly pine, with NIR outperforming FT-IR in predictive models.

Precision forestry in action 🌲👇
🔗 https://ow.ly/wQGe50XSYMG
#Spectroscopy
January 20, 2026 at 1:35 PM
2,000+ viscosity measurements in 25 minutes - from a single drop of blood.

Researchers are using vibrating microlaser droplets to enable high-throughput lipid assessment and real-time microscale rheology.

🔗 Read more: https://ow.ly/jznn50XTqEI
#BloodAnalysis #LabInnovation
January 19, 2026 at 1:30 PM
hat does leadership really mean in analytical science?

Three Power List 2025 honorees discuss culture, mentorship, soft skills, and why redefining leadership is essential for the future of analytical chemistry.

Part One of the roundtable 👇
🔗 https://ow.ly/XFhw50XSXxy
#AnalyticalScience
January 14, 2026 at 2:01 PM
🤖🧬 Data is no longer the bottleneck in biology. Meaning is.

In this interview, Sapient founder Mo Jain explains how AI-enhanced multi-omics and mass spectrometry are helping close the gap between molecular measurement and clinical insight.
https://ow.ly/z8yu50XItFV
#MultiOmics #MassSpec
January 13, 2026 at 1:15 PM
Can smarter tools end the “dark metabolome” debate?

Makarov, Amer, Bird & Tautenhahn on software + adaptive instruments to manage in-source fragmentation without losing discovery.

👉 https://ow.ly/wJWn50XKYAC

#Metabolomics #MassSpec #LCMS
January 7, 2026 at 2:30 PM
Starting 2026 with one of our biggest reads of 2025: 🧪 The Dark Metabolome: No Mere Figment?

Artifact or vast unknown chemistry? Pieter Dorrestein + Yasin El Abiead explain what’s at stake for interpreting untargeted LC-MS/MS (and why it matters).

Read: https://ow.ly/8TJg50XKWCW
#Metabolomics
January 5, 2026 at 1:00 PM
Ending the year with separation science 🧪

Fabrice Gritti reviews Bo Zhang’s precision-made LC microspheres and why independent control of particle size, PSD, morphology, mesopores, and chemistry could enable the experiments needed for real HPLC/UHPLC breakthroughs.
https://ow.ly/88N050XN3kg
December 31, 2025 at 11:00 AM
PFAS research on drinking water has surged over the last 20 years. 💧🧪

In this video, we share a bibliometric snapshot (2003–2023) tracking 1,281 studies and what they reveal about PFAS presence, detection, and removal.

Watch here: https://ow.ly/QtlI50XCLsT

#PFAS #DrinkingWater#EnvironmentalHealth
December 30, 2025 at 3:15 PM
Standardizing veterinary drug screening in food is tough.

This AOAC-Official LC-MS/MS method package supports ~150 compounds and includes dedicated streams for challenging classes (beta-lactams, aminoglycosides, tetracyclines).

Download the technical note: https://ow.ly/8BZm50XCLKa
#Sponsored
December 19, 2025 at 3:15 PM
🌊 LIBS under pressure (literally): how do you run laser spectroscopy at 4,000 m depth?

Rieck explains how his group has overcome the physical challenges of underwater plasma formation & how LIBS could become a cornerstone of future ocean intelligence systems.
https://ow.ly/s05s50XGnec
#Spectroscopy
December 15, 2025 at 1:55 PM
Can mass spec help CAR T break through solid tumors? 🔬

Joey Sheff explains how proteomics supports target discovery, epitope mapping, CAR characterization, and cell-state readouts linked to efficacy/exhaustion, plus why AI/ML + in-process analytics are next. https://ow.ly/FUCg50XBiiB

#MassSpec
December 12, 2025 at 3:00 PM
ipidomics is surging, but clinical adoption still hinges on one thing: robust quantitation. 🔬

Michal Holčapek explains why LC+HRMS synergy matters, how inter-lab harmonization/ring trials can fix variability, and where lipid biomarkers are headed.
🔗 https://ow.ly/4Yxy50XBnyC
#Lipidomics #MassSpec
December 10, 2025 at 1:00 PM
🧫🔬 A new AFM platform from ORNL maps biofilms across millimeter-scale surfaces while keeping nanoscale detail. Automation + machine learning = insights you’d never see with standard AFM.

We spoke with Liam Collins about the tech and what’s next.

Full story:
https://ow.ly/jorV50XtnQr
#Microscopy
December 5, 2025 at 2:50 PM
🧬⚗️ What happens when you revive a forgotten #chromatography technique?

Fabrice Gritti shares how deep dives into DNA physics helped bring slalom chromatography back to life, and why it could change how we separate large DNA and RNA in cell and gene therapy workflows.

🔗 https://ow.ly/4aEW50XvG5r
December 2, 2025 at 11:55 AM
2026 marks 60 years of Field Flow Fractionation — a technique that bridges biology, medicine, and materials science.

Alina Astefanei explores how FFF is revealing the hidden complexity of modern samples.
🔗 https://ow.ly/gCM350Xj6Ts

#FFF #AF4 #Science #Research
November 28, 2025 at 3:20 PM
🪐 New research suggests some organics in Enceladus’s plumes may form through Saturn’s radiation, not the subsurface ocean.

We spoke with Grace Richards to find out about what this means for finding biosignatures.

Full story:
https://ow.ly/Ikff50XtniQ
#Enceladus #Astrobiology #SpaceScience
November 26, 2025 at 11:40 AM
Honoring Prof. James D. Winefordner — a foundational figure in spectrochemistry, a mentor to many, and a pillar of our scientific community.

Gary Hieftje reflects on his extraordinary legacy.

🔗 https://ow.ly/RvkW50XxuhB

#AnalyticalScience #Spectrochemistry #InMemoriam #ScientificLegacy
November 25, 2025 at 3:15 PM