Amber Barton
@amberbarton.bsky.social
Bringing together 'omics 🧬 epidemiology 🌎 and immunology 💉 to dig into enteric infections and neglected tropical diseases. SEED Fellow @sangerinstitute.bsky.social
Reposted by Amber Barton
By sequencing the bacteria responsible for yaws, a debilitating childhood disease, experts have uncovered new insights into how these bacteria re-emerge and evade treatment 🧬
Find out how these can be used to help inform public health interventions ⤵️
www.sanger.ac.uk/news_item/ge...
Find out how these can be used to help inform public health interventions ⤵️
www.sanger.ac.uk/news_item/ge...
Genomics uncovers new ways to target chronic childhood disease
By sequencing the bacteria that cause the neglected disease yaws, researchers have found that while mass treatment can be successful, it can cause resistant strains to develop. They suggest that publi...
www.sanger.ac.uk
January 7, 2026 at 1:05 PM
By sequencing the bacteria responsible for yaws, a debilitating childhood disease, experts have uncovered new insights into how these bacteria re-emerge and evade treatment 🧬
Find out how these can be used to help inform public health interventions ⤵️
www.sanger.ac.uk/news_item/ge...
Find out how these can be used to help inform public health interventions ⤵️
www.sanger.ac.uk/news_item/ge...
Really pleased to see our work on yaws, and how mass drug administration shapes Treponema genomes, published in @lancetmicrobe.bsky.social!
sanger.ac.uk/news_item/genomics-uncovers-new-ways-to-target-chronic-childhood-disease/
www.thelancet.com/journals/lan...
sanger.ac.uk/news_item/genomics-uncovers-new-ways-to-target-chronic-childhood-disease/
www.thelancet.com/journals/lan...
Genomics uncovers new ways to target chronic childhood disease
By sequencing the bacteria that cause the neglected disease yaws, researchers have found that while mass treatment can be successful, it can cause resistant strains to develop. They suggest that publi...
www.sanger.ac.uk
January 7, 2026 at 6:38 PM
Really pleased to see our work on yaws, and how mass drug administration shapes Treponema genomes, published in @lancetmicrobe.bsky.social!
sanger.ac.uk/news_item/genomics-uncovers-new-ways-to-target-chronic-childhood-disease/
www.thelancet.com/journals/lan...
sanger.ac.uk/news_item/genomics-uncovers-new-ways-to-target-chronic-childhood-disease/
www.thelancet.com/journals/lan...
Reposted by Amber Barton
Out @lancetmicrobe.bsky.social & led @amberbarton.bsky.social We used WGS to look at Treponema population dynamics during community MDA for yaws tinyurl.com/bd6zu6xm
Intriguingly found sublineage associated w longer ulcer duration & lower antibody titres. Whether occurs in syphilis needs exploring
Intriguingly found sublineage associated w longer ulcer duration & lower antibody titres. Whether occurs in syphilis needs exploring
January 7, 2026 at 8:49 AM
Out @lancetmicrobe.bsky.social & led @amberbarton.bsky.social We used WGS to look at Treponema population dynamics during community MDA for yaws tinyurl.com/bd6zu6xm
Intriguingly found sublineage associated w longer ulcer duration & lower antibody titres. Whether occurs in syphilis needs exploring
Intriguingly found sublineage associated w longer ulcer duration & lower antibody titres. Whether occurs in syphilis needs exploring
Delighted to share our preprint on the evolution of pandemic cholera at its global source in the ganges basin!
doi.org/10.1101/2025.02.03.25321585
doi.org/10.1101/2025.02.03.25321585
Evolution of Pandemic Cholera at its Global Source
The seventh pandemic of cholera, caused by the 7th Pandemic El Tor Lineage (7PET) Vibrio cholerae, was previously shown to have emanated in three global waves from the Bay of Bengal, bordering Banglad...
www.medrxiv.org
February 5, 2025 at 12:59 PM
Delighted to share our preprint on the evolution of pandemic cholera at its global source in the ganges basin!
doi.org/10.1101/2025.02.03.25321585
doi.org/10.1101/2025.02.03.25321585
Had a wonderful time at 17th Asian Conference on Diarrhoeal Disease and Nutrition in Nepal- fantastic to meet up with infection researchers from all over the world, share results, chair a session for the first time and explore Kathmandu!
December 13, 2024 at 2:34 PM
Had a wonderful time at 17th Asian Conference on Diarrhoeal Disease and Nutrition in Nepal- fantastic to meet up with infection researchers from all over the world, share results, chair a session for the first time and explore Kathmandu!
Reposted by Amber Barton
Pleased to share this preprint on Yaws transmission dynamics following mass azithromycin administration, led by Amber Barton www.medrxiv.org/content/10.1...
Following MDA campaign, we sequenced >half of infections, showing recrudescence driven by existing lineages & persistence linked to key SNPs.
Following MDA campaign, we sequenced >half of infections, showing recrudescence driven by existing lineages & persistence linked to key SNPs.
The Effect of Repeated Mass Drug Administration on the Transmission of Yaws: A Genomic Epidemiology Study
Background: Yaws, a neglected tropical disease caused by Treponema pallidum subspecies pertenue, has evaded eradication, in part due to a high proportion of asymptomatic cases. A cluster-randomised tr...
www.medrxiv.org
October 29, 2024 at 10:03 AM
Pleased to share this preprint on Yaws transmission dynamics following mass azithromycin administration, led by Amber Barton www.medrxiv.org/content/10.1...
Following MDA campaign, we sequenced >half of infections, showing recrudescence driven by existing lineages & persistence linked to key SNPs.
Following MDA campaign, we sequenced >half of infections, showing recrudescence driven by existing lineages & persistence linked to key SNPs.