Alessandro Donada
@alessandrodonada.bsky.social
"Definitely still a young hematology researcher (don’t ask how young) @Institut Curie | Big on participative research & quant bio 🧪 | Wannabe Intern at the Ministry of Silly Walks
Reposted by Alessandro Donada
The #ISEH2025 🏯 program is here and features world-renowned scientists showcasing the latest in experimental hematology. Don't miss these sessions, including the ISEH/JSH symposium on stress hematopoiesis with Drs. Toshio Suda and Hitoshi Takizawa ➡️ www.iseh.org/2025Scientif...
July 30, 2025 at 5:30 PM
The #ISEH2025 🏯 program is here and features world-renowned scientists showcasing the latest in experimental hematology. Don't miss these sessions, including the ISEH/JSH symposium on stress hematopoiesis with Drs. Toshio Suda and Hitoshi Takizawa ➡️ www.iseh.org/2025Scientif...
So interesting!
LS, an emergent form of acute leukemia relapse after antigen-targeted therapy, primarily in B-ALL, has dismal outcomes. buff.ly/59xI6qv #hemesky
July 31, 2025 at 6:31 AM
So interesting!
A gentleman and a scholar indeed! What a pleasant chat with @abattacks.bsky.social, make sure to check out our interview! Also, a submitted post from @lvchosen1.bsky.social and at least 25 preprints to review! #hemesky
The July #PreprintWatch features 25 fresh preprints that span hematopoietic development, leukemogenesis, and the latest in tech development. Plus, a video chat with @abattacks.bsky.social - one of our featured community submitters! Explore on www.simplyblood.org
July 25, 2025 at 6:22 AM
A gentleman and a scholar indeed! What a pleasant chat with @abattacks.bsky.social, make sure to check out our interview! Also, a submitted post from @lvchosen1.bsky.social and at least 25 preprints to review! #hemesky
Let's do this!
Happy to have received a POC ERC to scale up the microscopy of motile cells, like our favorite hematopoietic cells, using microchip and AI based image analysis! project with the very best: @alessandrodonada.bsky.social, Morgane Burg, Hervé Isambert and Tizziana Tocci. Thank you ERC!
Over €20 million to turn frontier science into practical solutions
The European Research Council (ERC) has today announced the first group of researchers to be awarded ERC Proof of Concept Grants in 2025. In this initial round of the 2025 competition, 150 projects wi...
erc.europa.eu
July 21, 2025 at 9:14 AM
Let's do this!
Best way to keep up with the newest research! #HemeSky
The #PreprintWatch is here! Read the highlights of the latest and most interesting preprints on our blog www.simplyblood.org and submit your own to be featured.
simply blood
Deconstructing blood cell research, building the hematology community
www.simplyblood.org
July 2, 2025 at 6:41 AM
Best way to keep up with the newest research! #HemeSky
🧬 What if your blood cells remembered how their ancestors divided?
Our new preprint (www.biorxiv.org/content/10.1...) explores clonal memory in human blood stem cells — and how it breaks down in leukaemia.
📄 "Clonal memory of cell division..."
Our new preprint (www.biorxiv.org/content/10.1...) explores clonal memory in human blood stem cells — and how it breaks down in leukaemia.
📄 "Clonal memory of cell division..."
a man with a beard is wearing a hat and a striped shirt and saying `` do you remember '' .
ALT: a man with a beard is wearing a hat and a striped shirt and saying `` do you remember '' .
media.tenor.com
June 25, 2025 at 9:22 AM
🧬 What if your blood cells remembered how their ancestors divided?
Our new preprint (www.biorxiv.org/content/10.1...) explores clonal memory in human blood stem cells — and how it breaks down in leukaemia.
📄 "Clonal memory of cell division..."
Our new preprint (www.biorxiv.org/content/10.1...) explores clonal memory in human blood stem cells — and how it breaks down in leukaemia.
📄 "Clonal memory of cell division..."
Reposted by Alessandro Donada
This Article analyzes human hematopoiesis in humanized bone marrow in immune-deficient mice, showing dynamic structures supporting human hematopoietic development. Findings emphasize significance of the models for investigating human hematopoietic development & leukemogenesis👉https://bit.ly/42Czbaw
June 24, 2025 at 8:01 AM
This Article analyzes human hematopoiesis in humanized bone marrow in immune-deficient mice, showing dynamic structures supporting human hematopoietic development. Findings emphasize significance of the models for investigating human hematopoietic development & leukemogenesis👉https://bit.ly/42Czbaw
Reposted by Alessandro Donada
🚨🚨 We're hiring! 🚨🚨
The Single-cell Analytics Innovation Lab (SAIL) at @mskcancercenter.bsky.social is looking for a Junior Technician to join our wet lab team!
You'll work with spatial genomics and single-cell technologies, helping us push the boundaries of cutting-edge analysis in cancer research.
The Single-cell Analytics Innovation Lab (SAIL) at @mskcancercenter.bsky.social is looking for a Junior Technician to join our wet lab team!
You'll work with spatial genomics and single-cell technologies, helping us push the boundaries of cutting-edge analysis in cancer research.
June 23, 2025 at 8:27 PM
🚨🚨 We're hiring! 🚨🚨
The Single-cell Analytics Innovation Lab (SAIL) at @mskcancercenter.bsky.social is looking for a Junior Technician to join our wet lab team!
You'll work with spatial genomics and single-cell technologies, helping us push the boundaries of cutting-edge analysis in cancer research.
The Single-cell Analytics Innovation Lab (SAIL) at @mskcancercenter.bsky.social is looking for a Junior Technician to join our wet lab team!
You'll work with spatial genomics and single-cell technologies, helping us push the boundaries of cutting-edge analysis in cancer research.
What are you waiting for? Best society you can be involved in!
The ISEH Call for Volunteers closes this Wednesday. Express your interest in one of ISEH's many committees by completing our volunteer interest form. 👉 www.iseh.org/ISEHCommittees
June 10, 2025 at 8:42 PM
What are you waiting for? Best society you can be involved in!
Make him pay ladies. And a lot of respect for a postdoc taking this type of stance, we can only hope to be like that.
“I want any privilege I have at this point, which I’ve worked really hard to get, to use my name because I feel like it’s my duty to stand up for science," says Nicole Maphis, first in her family to go to university.
My latest @nature.com story.
www.nature.com/articles/d41...
My latest @nature.com story.
www.nature.com/articles/d41...
‘We were ready for this’: meet the scientists suing the Trump administration to reinstate terminated grants
Judge sets court date to hear the US government detail how termination directives were made.
www.nature.com
June 6, 2025 at 11:32 AM
Make him pay ladies. And a lot of respect for a postdoc taking this type of stance, we can only hope to be like that.
Reposted by Alessandro Donada
Invited speaker @trowbridgelab.bsky.social will share her work this September at #ISEH2025 🏯 Learn more about the incredible science to expect this year and register today! youtu.be/RnyyurVaZrc
June 3, 2025 at 2:31 PM
Invited speaker @trowbridgelab.bsky.social will share her work this September at #ISEH2025 🏯 Learn more about the incredible science to expect this year and register today! youtu.be/RnyyurVaZrc
Reposted by Alessandro Donada
Calls for volunteers to serve on a variety of committees for the @isehsociety.bsky.social are open now! Check out these opportunities if you're interested in developing leadership skills and your professional network. It takes a village! www.iseh.org/page/ISEHCom...
ISEH Committees - International Society for Experimental Hematology
www.iseh.org
June 4, 2025 at 3:26 PM
Calls for volunteers to serve on a variety of committees for the @isehsociety.bsky.social are open now! Check out these opportunities if you're interested in developing leadership skills and your professional network. It takes a village! www.iseh.org/page/ISEHCom...
Find 20 minutes of your time and listen to this interview, plenty of valuable insights!
Honestly, am so honoured that the next generation of researchers selected me to speak. This was fun to record!
We're kicking off our Interview Spotlight Series with the 2025 New Investigator Invited Speaker @shalinhnaik.bsky.social Prof. Naik dives into his current work, career inspirations and life outside of the lab. Watch the interview on www.simplyblood.org
June 2, 2025 at 4:26 PM
Find 20 minutes of your time and listen to this interview, plenty of valuable insights!
Reposted by Alessandro Donada
Excited to see the first commentary in Experimental Hematology (@isehsociety.bsky.social)! Kudos to Aishwarya, Linde @lindemileslab.bsky.social, and Grant @challenlab.bsky.social for highlighting recent papers in Exp Hem on cell-extrinsic factors in Tet2-mutant clonal hematopoiesis!! bit.ly/4k3pEAI
Cell-extrinsic factors contribute toward myeloid-biased expansion in Tet2-mutant clonal hematopoiesis
Hematopoietic stem cells (HSCs) acquire somatic mutations throughout life, with the
frequency of mutational incidence increasing with age [1]. Occasionally, certain mutations
confer a fitness advantag...
bit.ly
May 23, 2025 at 3:04 PM
Excited to see the first commentary in Experimental Hematology (@isehsociety.bsky.social)! Kudos to Aishwarya, Linde @lindemileslab.bsky.social, and Grant @challenlab.bsky.social for highlighting recent papers in Exp Hem on cell-extrinsic factors in Tet2-mutant clonal hematopoiesis!! bit.ly/4k3pEAI
Reposted by Alessandro Donada
🔬 Passionate about experimental hematology?
Apply now for the final @carrerasleaders.bsky.social Call and join our team to work at the intersection of epigenetics, chromatin biology, and blood cancer.
#Hematology #Epigenetics #postdoc
Learn more (shorturl.at/5x5sw) & Apply 👇
Apply now for the final @carrerasleaders.bsky.social Call and join our team to work at the intersection of epigenetics, chromatin biology, and blood cancer.
#Hematology #Epigenetics #postdoc
Learn more (shorturl.at/5x5sw) & Apply 👇
May 22, 2025 at 7:02 AM
🔬 Passionate about experimental hematology?
Apply now for the final @carrerasleaders.bsky.social Call and join our team to work at the intersection of epigenetics, chromatin biology, and blood cancer.
#Hematology #Epigenetics #postdoc
Learn more (shorturl.at/5x5sw) & Apply 👇
Apply now for the final @carrerasleaders.bsky.social Call and join our team to work at the intersection of epigenetics, chromatin biology, and blood cancer.
#Hematology #Epigenetics #postdoc
Learn more (shorturl.at/5x5sw) & Apply 👇
That was a great chat, Christiana really nailed it! Have a look, her work is an absolute must, and a really original approach to long-standing questions on HSCs division
In this month's #PreprintWatch we’re diving into studies using less explored animal models and exciting technologies pushing the boundaries of advanced cell culture. And don't miss the video chat with Christiana Georgiou from the Lo Celso Lab www.simplyblood.org
May 22, 2025 at 6:57 AM
That was a great chat, Christiana really nailed it! Have a look, her work is an absolute must, and a really original approach to long-standing questions on HSCs division
Reposted by Alessandro Donada
Normal human HSCs do not require FLT3 to engraft and sustain hematopoiesis. buff.ly/cfOqhWD #hemesky #myeloidneoplasia
May 20, 2025 at 3:05 PM
Normal human HSCs do not require FLT3 to engraft and sustain hematopoiesis. buff.ly/cfOqhWD #hemesky #myeloidneoplasia
Reposted by Alessandro Donada
New paper from our lab! In this study, we show that AML cells critically depend on LDHA to maintain their NAD+/NADH balance. Congrats to first author Ayşegül Erdem and all co-authors! cancerandmetabolism.biomedcentral.com/articles/10....
Lactate dehydrogenase A-coupled NAD+ regeneration is critical for acute myeloid leukemia cell survival - Cancer & Metabolism
Background Enhanced glycolysis plays a pivotal role in fueling the aberrant proliferation, survival and therapy resistance of acute myeloid leukemia (AML) cells. Here, we aimed to elucidate the extent...
cancerandmetabolism.biomedcentral.com
May 19, 2025 at 9:27 PM
New paper from our lab! In this study, we show that AML cells critically depend on LDHA to maintain their NAD+/NADH balance. Congrats to first author Ayşegül Erdem and all co-authors! cancerandmetabolism.biomedcentral.com/articles/10....
Reposted by Alessandro Donada
Tomorrow - Register for the NIC Gene Therapy webinar with Dr. Mitchell Weiss and Prof. Luigi Naldini. Join live to hear about gene therapy for hemoglobinopathies and emerging gene editing technologies ➡️ www.iseh.org/ISEHWebinars
May 19, 2025 at 6:29 PM
Tomorrow - Register for the NIC Gene Therapy webinar with Dr. Mitchell Weiss and Prof. Luigi Naldini. Join live to hear about gene therapy for hemoglobinopathies and emerging gene editing technologies ➡️ www.iseh.org/ISEHWebinars
Reposted by Alessandro Donada
This month’s #ParisPostdocsSeminar features @laurasalavessa.bsky.social from @inem-necker.bsky.social, presenting her latest results on the transfer and uptake of melanin in keratinocytes for skin homeostasis!
📅 Tuesday, 27 May 2025
🕚 11:00–12:00 CET
📍 Amphitheatre Agnès Ullmann, @pasteur.fr
📅 Tuesday, 27 May 2025
🕚 11:00–12:00 CET
📍 Amphitheatre Agnès Ullmann, @pasteur.fr
May 19, 2025 at 12:01 PM
This month’s #ParisPostdocsSeminar features @laurasalavessa.bsky.social from @inem-necker.bsky.social, presenting her latest results on the transfer and uptake of melanin in keratinocytes for skin homeostasis!
📅 Tuesday, 27 May 2025
🕚 11:00–12:00 CET
📍 Amphitheatre Agnès Ullmann, @pasteur.fr
📅 Tuesday, 27 May 2025
🕚 11:00–12:00 CET
📍 Amphitheatre Agnès Ullmann, @pasteur.fr
"Peer review can be thought of as a zero sum game:[...] I submit harsh reviews because those are what I get on my own papers."
Brilliant reading from @biologists.bsky.social's Journal of Cell Science
journals.biologists.com/jcs/article/...
Brilliant reading from @biologists.bsky.social's Journal of Cell Science
journals.biologists.com/jcs/article/...
Let's review I
Good morning, bonjour, buongiorno, guten morgen, dzien dobry, maj po! (Sorry if I left out your language, but I did get you if you are Klingon. In any case, hi there!). It is a bea-u-ti-ful spring day...
journals.biologists.com
May 19, 2025 at 6:39 AM
"Peer review can be thought of as a zero sum game:[...] I submit harsh reviews because those are what I get on my own papers."
Brilliant reading from @biologists.bsky.social's Journal of Cell Science
journals.biologists.com/jcs/article/...
Brilliant reading from @biologists.bsky.social's Journal of Cell Science
journals.biologists.com/jcs/article/...