Katherine Aird
@airdlab.bsky.social
My lab studies the interplay between cancer metabolism and cell cycle dysregulation. Professor at The Wistar Institute
airdlab.com
airdlab.com
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Katherine Aird
@airdlab.bsky.social
· Aug 14
The chemotherapy-induced senescence-associated secretome promotes cell detachment and metastatic dissemination through metabolic reprogramming
Cellular senescence, characterized by a stable cell cycle arrest, is a well-documented consequence of several widely used chemotherapeutics that has context-dependent roles in cancer. Although senesce...
www.biorxiv.org
The summer has been busy! Along with the move and a PhD defense, we have updated two preprints:
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Katherine Aird
Excited to share the Ovarian Cancer Research Syndicate line-up of speakers for the fall. Please share. We have amazing trainees presenting and the latest from leaders in the field.
@powelldrescher.bsky.social @srocf.bsky.social @pennmedcso.bsky.social @penncancer.bsky.social
@powelldrescher.bsky.social @srocf.bsky.social @pennmedcso.bsky.social @penncancer.bsky.social
September 22, 2025 at 10:23 PM
Excited to share the Ovarian Cancer Research Syndicate line-up of speakers for the fall. Please share. We have amazing trainees presenting and the latest from leaders in the field.
@powelldrescher.bsky.social @srocf.bsky.social @pennmedcso.bsky.social @penncancer.bsky.social
@powelldrescher.bsky.social @srocf.bsky.social @pennmedcso.bsky.social @penncancer.bsky.social
My lab at The Wistar Institute is recruiting on multiple levels!
We are looking for a research technician and/or senior lab manager to help support all lab projects. Cell culture, molecular biology, and animal handling expertise and 3+ years of experience needed. Apply here: lnkd.in/ecvdTwkf
We are looking for a research technician and/or senior lab manager to help support all lab projects. Cell culture, molecular biology, and animal handling expertise and 3+ years of experience needed. Apply here: lnkd.in/ecvdTwkf
Job Details | Dayforce Jobs
Find your next adventure
lnkd.in
September 18, 2025 at 3:45 PM
My lab at The Wistar Institute is recruiting on multiple levels!
We are looking for a research technician and/or senior lab manager to help support all lab projects. Cell culture, molecular biology, and animal handling expertise and 3+ years of experience needed. Apply here: lnkd.in/ecvdTwkf
We are looking for a research technician and/or senior lab manager to help support all lab projects. Cell culture, molecular biology, and animal handling expertise and 3+ years of experience needed. Apply here: lnkd.in/ecvdTwkf
Big day for multiple lab members who celebrated a promotion! Congrats to Apoorva Uboveja for promotion to Staff Scientist and Aidan Cole for starting as a postdoc! I am now a full professor too 🤓 Want to learn more about our science or join the lab? Visit Airdlab.com
Aird Lab
Airdlab.com
September 3, 2025 at 10:00 AM
Big day for multiple lab members who celebrated a promotion! Congrats to Apoorva Uboveja for promotion to Staff Scientist and Aidan Cole for starting as a postdoc! I am now a full professor too 🤓 Want to learn more about our science or join the lab? Visit Airdlab.com
The summer has been busy! Along with the move and a PhD defense, we have updated two preprints:
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
The chemotherapy-induced senescence-associated secretome promotes cell detachment and metastatic dissemination through metabolic reprogramming
Cellular senescence, characterized by a stable cell cycle arrest, is a well-documented consequence of several widely used chemotherapeutics that has context-dependent roles in cancer. Although senesce...
www.biorxiv.org
August 14, 2025 at 12:03 PM
The summer has been busy! Along with the move and a PhD defense, we have updated two preprints:
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
I could not be more excited to finally announce that my lab will be moving to The Wistar Institute in Philadelphia in early September! While this is somewhat of a homecoming for me, it is a new adventure for the 6 lab members moving with me! More details to come about new roles and opportunities!
Job Details | Dayforce Jobs
Find your next adventure
jobs.dayforcehcm.com
July 22, 2025 at 6:17 PM
I could not be more excited to finally announce that my lab will be moving to The Wistar Institute in Philadelphia in early September! While this is somewhat of a homecoming for me, it is a new adventure for the 6 lab members moving with me! More details to come about new roles and opportunities!
Our preprint by @raquelbuj.bsky.social was highlighted! What a cool idea to give early career scientists the opportunity to practice peer review skills! See the updated preprint: www.biorxiv.org/content/10.1....
April 23, 2025 at 10:22 PM
Our preprint by @raquelbuj.bsky.social was highlighted! What a cool idea to give early career scientists the opportunity to practice peer review skills! See the updated preprint: www.biorxiv.org/content/10.1....
Anyone else having trouble contacting Fetterman? I’ve tried both his DC and Pittsburgh office numbers, and it keeps disconnecting
March 14, 2025 at 1:22 PM
Anyone else having trouble contacting Fetterman? I’ve tried both his DC and Pittsburgh office numbers, and it keeps disconnecting
Reposted by Katherine Aird
Bluetorial: The rationale for the “NIH” indirect cost “plan” is based on misunderstood (unintentional or intentional) accounting and math
The value of real government transparency
The value of real government transparency
a cartoon of homer simpson holding a card
ALT: a cartoon of homer simpson holding a card
media.tenor.com
February 13, 2025 at 3:48 AM
Bluetorial: The rationale for the “NIH” indirect cost “plan” is based on misunderstood (unintentional or intentional) accounting and math
The value of real government transparency
The value of real government transparency
If you are worried about the constitutional crisis, NIH/NSF funding, diversity issues, or anything else: CONTACT YOUR REPRESENTATIVES.
For those in PA:
Dave McCormick: 202 224 6324 (www.mccormick.senate.gov/share-your-o...)
John Fetterman: 202 224 4254 (www.fetterman.senate.gov/contact/)
For those in PA:
Dave McCormick: 202 224 6324 (www.mccormick.senate.gov/share-your-o...)
John Fetterman: 202 224 4254 (www.fetterman.senate.gov/contact/)
Contact - Summer Lee
summerlee.house.gov
February 12, 2025 at 1:52 PM
If you are worried about the constitutional crisis, NIH/NSF funding, diversity issues, or anything else: CONTACT YOUR REPRESENTATIVES.
For those in PA:
Dave McCormick: 202 224 6324 (www.mccormick.senate.gov/share-your-o...)
John Fetterman: 202 224 4254 (www.fetterman.senate.gov/contact/)
For those in PA:
Dave McCormick: 202 224 6324 (www.mccormick.senate.gov/share-your-o...)
John Fetterman: 202 224 4254 (www.fetterman.senate.gov/contact/)
Reposted by Katherine Aird
BREAKING: Federal judge in Boston broadens block on Trump's NIH grant 15% overhead limit (indirect cost rates) to all recipients nationwide. Doc: www.documentcloud.org/documents/25...
#TROpalooza ain't done
#TROpalooza ain't done
AAMCOrd021025
www.documentcloud.org
February 11, 2025 at 5:22 AM
BREAKING: Federal judge in Boston broadens block on Trump's NIH grant 15% overhead limit (indirect cost rates) to all recipients nationwide. Doc: www.documentcloud.org/documents/25...
#TROpalooza ain't done
#TROpalooza ain't done
Reposted by Katherine Aird
Reposted by Katherine Aird
not paying indirect costs for research is like only paying the players in the Super Bowl.
can't have a Super Bowl without coaches, referees, security, janitors, announcers, stadium staff, and a stadium - and you can't have research without supporting people and facilities
can't have a Super Bowl without coaches, referees, security, janitors, announcers, stadium staff, and a stadium - and you can't have research without supporting people and facilities
February 9, 2025 at 11:00 PM
not paying indirect costs for research is like only paying the players in the Super Bowl.
can't have a Super Bowl without coaches, referees, security, janitors, announcers, stadium staff, and a stadium - and you can't have research without supporting people and facilities
can't have a Super Bowl without coaches, referees, security, janitors, announcers, stadium staff, and a stadium - and you can't have research without supporting people and facilities
Cutting NIH funds hurts all Americans.
Why? Three main reasons:
#1: These funds support a huge industry in all states. For every $1 of NIH funding generated, there is a short-term return of ~$2.46 in economic activity. $4B in cuts will take away $10B from the economy.
Why? Three main reasons:
#1: These funds support a huge industry in all states. For every $1 of NIH funding generated, there is a short-term return of ~$2.46 in economic activity. $4B in cuts will take away $10B from the economy.
February 9, 2025 at 4:27 PM
Cutting NIH funds hurts all Americans.
Why? Three main reasons:
#1: These funds support a huge industry in all states. For every $1 of NIH funding generated, there is a short-term return of ~$2.46 in economic activity. $4B in cuts will take away $10B from the economy.
Why? Three main reasons:
#1: These funds support a huge industry in all states. For every $1 of NIH funding generated, there is a short-term return of ~$2.46 in economic activity. $4B in cuts will take away $10B from the economy.
So proud of Richard Fang, a senior undergrad in the lab, highlighted in this nice write-up. He is about to graduate and move on to bigger and better things as an MD/PhD student, and we will miss him! www.pitt.edu/pittwire/fea...
This Pitt senior and cancer researcher is one to keep watching
Here’s what’s next for Richard Su Fang, a Goldwater scholar who has already received interview invitations from 17 MD/PhD programs.
www.pitt.edu
December 13, 2024 at 5:36 PM
So proud of Richard Fang, a senior undergrad in the lab, highlighted in this nice write-up. He is about to graduate and move on to bigger and better things as an MD/PhD student, and we will miss him! www.pitt.edu/pittwire/fea...
Reposted by Katherine Aird
Good Sunday. This weekly summary of papers in #cancermetabolism and #mitochondrialbiology is full of exciting discoveries. Check it here: biomed.news/bims-camemi/... @biomednews.bsky.social
"The greatest obstacle to living is expectancy, which hangs upon tomorrow and loses today."-Seneca
"The greatest obstacle to living is expectancy, which hangs upon tomorrow and loses today."-Seneca
a poster that says " never stop reading " next to a magazine
ALT: a poster that says " never stop reading " next to a magazine
media.tenor.com
December 8, 2024 at 6:34 AM
Good Sunday. This weekly summary of papers in #cancermetabolism and #mitochondrialbiology is full of exciting discoveries. Check it here: biomed.news/bims-camemi/... @biomednews.bsky.social
"The greatest obstacle to living is expectancy, which hangs upon tomorrow and loses today."-Seneca
"The greatest obstacle to living is expectancy, which hangs upon tomorrow and loses today."-Seneca
Reposted by Katherine Aird
This project started with a talented grad student noticing that low levels of sGC correspond to the ability of CSPC cells to evade androgen deprivation-induced senescence. Six years (2 in peer review) and one pandemic later, voila…
aacrjournals.org/cancerres/ar...
aacrjournals.org/cancerres/ar...
Stimulating Soluble Guanylyl Cyclase with the Clinical Agonist Riociguat Restrains the Development and Progression of Castration-Resistant Prostate Cancer
Abstract. Castration-resistant prostate cancer (CRPC) is incurable and fatal, making prostate cancer the second-leading cancer-related cause of death for American men. CRPC results from therapeutic re...
aacrjournals.org
December 3, 2024 at 11:55 PM
This project started with a talented grad student noticing that low levels of sGC correspond to the ability of CSPC cells to evade androgen deprivation-induced senescence. Six years (2 in peer review) and one pandemic later, voila…
aacrjournals.org/cancerres/ar...
aacrjournals.org/cancerres/ar...
Reposted by Katherine Aird
December 4, 2024 at 4:47 AM
Reposted by Katherine Aird
As the community grows fast, here is an updated Metabolism Starter Pack 2 with loads of exciting scientists
go.bsky.app/CH1MctZ
go.bsky.app/CH1MctZ
December 4, 2024 at 5:43 AM
As the community grows fast, here is an updated Metabolism Starter Pack 2 with loads of exciting scientists
go.bsky.app/CH1MctZ
go.bsky.app/CH1MctZ
Want a cliffsnote version of amazing cancer discoveries from 2024? Check out the Dec issue of Cancer Discovery. It was hard to pick just 1 paper to highlight!
What were the most inspiring 2024 discoveries in cancer?
Cancer Discovery asked me, Katherine Aird, Aadel Chaudhuri, Jennifer Guerriero, Shiri Gur-Cohen, Benjamin Izar, Brittany Jenkins, Delphine Merino, Alejo Rodriguez-Fraticelli & Shensi Shen, & here's what we said
aacrjournals.org/cancerdiscov...
Cancer Discovery asked me, Katherine Aird, Aadel Chaudhuri, Jennifer Guerriero, Shiri Gur-Cohen, Benjamin Izar, Brittany Jenkins, Delphine Merino, Alejo Rodriguez-Fraticelli & Shensi Shen, & here's what we said
aacrjournals.org/cancerdiscov...
December 4, 2024 at 11:22 AM
Want a cliffsnote version of amazing cancer discoveries from 2024? Check out the Dec issue of Cancer Discovery. It was hard to pick just 1 paper to highlight!
Reposted by Katherine Aird
Hi #TeamMassSpec! #FeMS+ has joined BlueSky! Please share and get the word out so we can build up a base here.
November 30, 2024 at 2:00 PM
Hi #TeamMassSpec! #FeMS+ has joined BlueSky! Please share and get the word out so we can build up a base here.
Do you want to read about what it’s like to be a mid- or senior career female scientist? Read this. The sexism and misogyny absolutely gets worse the higher you go.
Reading the paper in Cell about how to close the scissor plots in gender representation at senior academic positions, I feel just a touch of pessimism. Having reached a level of seniority (middle management) I didn’t think I ever would, I read these great ideas wanting more, much more /1.
Closing the scissor-shaped curve: Strategies to promote gender equality in academia
Gender inequality in STEM fields remains pervasive and undermines the ability for
talented individuals to excel. Despite advances, women still encounter obstacles in
pursuing academic careers and reac...
www.cell.com
December 1, 2024 at 1:49 PM
Do you want to read about what it’s like to be a mid- or senior career female scientist? Read this. The sexism and misogyny absolutely gets worse the higher you go.
Reposted by Katherine Aird
Goood Sunday, all! A very exciting curated issue of papers in #cancermetabolism and #mitochondrialbiology is waiting for you here: biomed.news/bims-camemi/... @biomednews.bsky.social #readingtime
"Most human beings have an almost infinite capacity for taking things for granted."-Aldous Huxley
"Most human beings have an almost infinite capacity for taking things for granted."-Aldous Huxley
a drawing of a man with glasses and gloves with the words science mode written above him
ALT: a drawing of a man with glasses and gloves with the words science mode written above him
media.tenor.com
December 1, 2024 at 5:51 AM
Goood Sunday, all! A very exciting curated issue of papers in #cancermetabolism and #mitochondrialbiology is waiting for you here: biomed.news/bims-camemi/... @biomednews.bsky.social #readingtime
"Most human beings have an almost infinite capacity for taking things for granted."-Aldous Huxley
"Most human beings have an almost infinite capacity for taking things for granted."-Aldous Huxley
Reposted by Katherine Aird
Dietary Restriction Enhances CD8⁺ T Cell Ketolysis to Limit Exhaustion and Boost Anti-Tumor Immunity 🧪
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Dietary Restriction Enhances CD8⁺ T Cell Ketolysis to Limit Exhaustion and Boost Anti-Tumor Immunity
Reducing calorie intake without malnutrition limits tumor progression but the underlying mechanisms are poorly understood. Here we show that dietary restriction (DR) suppresses tumor growth by enhanci...
www.biorxiv.org
December 1, 2024 at 6:42 AM
Dietary Restriction Enhances CD8⁺ T Cell Ketolysis to Limit Exhaustion and Boost Anti-Tumor Immunity 🧪
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
It’s my lab’s 8th birthday today. I am overwhelmed with gratitude to be able to do this job, mentor my trainees (currently killing it 🤩), and interact with the smartest colleagues and collaborators one could ask for. Mid-career hasn’t been easy, and I’m thankful to still be making cool discoveries.
November 28, 2024 at 1:19 PM
It’s my lab’s 8th birthday today. I am overwhelmed with gratitude to be able to do this job, mentor my trainees (currently killing it 🤩), and interact with the smartest colleagues and collaborators one could ask for. Mid-career hasn’t been easy, and I’m thankful to still be making cool discoveries.
Reposted by Katherine Aird
Good morning all! Another week of fantastic papers in #cancermetabolism and #mitochondrialbiology has just passed. Don't miss these papers, find them here: biomed.news/bims-camemi/... @biomednews.bsky.social
"Calm down. Both your sins and your good deeds will be lost in oblivion." -Czesław Miłosz
"Calm down. Both your sins and your good deeds will be lost in oblivion." -Czesław Miłosz
a cartoon of a robot reading a newspaper with the words morning news below him
ALT: a cartoon of a robot reading a newspaper with the words morning news below him
media.tenor.com
November 24, 2024 at 6:32 AM
Good morning all! Another week of fantastic papers in #cancermetabolism and #mitochondrialbiology has just passed. Don't miss these papers, find them here: biomed.news/bims-camemi/... @biomednews.bsky.social
"Calm down. Both your sins and your good deeds will be lost in oblivion." -Czesław Miłosz
"Calm down. Both your sins and your good deeds will be lost in oblivion." -Czesław Miłosz