#Thyroid disorders affect 200 million+ people worldwide – a heavy burden for patients, their families and health systems. Advancing research in this area is a public health priority.
Full findings of the #EndoCompass Research Roadmap ninth paper 👉 doi.org/10.1093/ejen...
Full findings of the #EndoCompass Research Roadmap ninth paper 👉 doi.org/10.1093/ejen...
November 11, 2025 at 1:07 PM
#Thyroid disorders affect 200 million+ people worldwide – a heavy burden for patients, their families and health systems. Advancing research in this area is a public health priority.
Full findings of the #EndoCompass Research Roadmap ninth paper 👉 doi.org/10.1093/ejen...
Full findings of the #EndoCompass Research Roadmap ninth paper 👉 doi.org/10.1093/ejen...
Did anyone in the fully hearing community hear the name of the tune Miriam O'Callaghan referred to right after 'Sí Mór & Sí Beog'?
...it was very pretty, but I'm willing to bet it was not, as the ridiculously teeny subtitles said: "Thyroid Music" 🙄
...it was very pretty, but I'm willing to bet it was not, as the ridiculously teeny subtitles said: "Thyroid Music" 🙄
November 11, 2025 at 12:12 PM
Did anyone in the fully hearing community hear the name of the tune Miriam O'Callaghan referred to right after 'Sí Mór & Sí Beog'?
...it was very pretty, but I'm willing to bet it was not, as the ridiculously teeny subtitles said: "Thyroid Music" 🙄
...it was very pretty, but I'm willing to bet it was not, as the ridiculously teeny subtitles said: "Thyroid Music" 🙄
Thyrafemme™ Official Site | Clean Vegan Thyroid Carey
Revive your feminine energy with Thyrafemme™. Clean, stimulant-free thyroid support with iodine, L-tyrosine, ashwagandha, and essential minerals.
tharafemme.com
Thyrafemme, Thyroid support, Hormone balance
Revive your feminine energy with Thyrafemme™. Clean, stimulant-free thyroid support with iodine, L-tyrosine, ashwagandha, and essential minerals.
tharafemme.com
Thyrafemme, Thyroid support, Hormone balance
Thyrafemme™ Official Site | Clean Vegan Thyroid Carey
Revive your feminine energy with Thyrafemme™. Clean, stimulant-free thyroid support with iodine, L-tyrosine, ashwagandha, and essential minerals.
tharafemme.com
November 11, 2025 at 11:43 AM
Thyrafemme™ Official Site | Clean Vegan Thyroid Carey
Revive your feminine energy with Thyrafemme™. Clean, stimulant-free thyroid support with iodine, L-tyrosine, ashwagandha, and essential minerals.
tharafemme.com
Thyrafemme, Thyroid support, Hormone balance
Revive your feminine energy with Thyrafemme™. Clean, stimulant-free thyroid support with iodine, L-tyrosine, ashwagandha, and essential minerals.
tharafemme.com
Thyrafemme, Thyroid support, Hormone balance
I'm still disappointed I wasn't allowed to take home my half a thyroid with attached tumour when it was removed a few years ago, wanted to keep it in a jar on the coffee table to deter guests!
November 11, 2025 at 10:50 AM
I'm still disappointed I wasn't allowed to take home my half a thyroid with attached tumour when it was removed a few years ago, wanted to keep it in a jar on the coffee table to deter guests!
"Sorry we dont actually do ultrasounds of the thyroid" like what??? Why do you even list it on your website then???
November 11, 2025 at 10:29 AM
"Sorry we dont actually do ultrasounds of the thyroid" like what??? Why do you even list it on your website then???
Morning Kaci 👋🏻 I hope things are better today. I have to take Joli to the vet for her thyroid blood test, she’s a real demon even with gabapentin! 🙀😹
November 11, 2025 at 10:06 AM
Morning Kaci 👋🏻 I hope things are better today. I have to take Joli to the vet for her thyroid blood test, she’s a real demon even with gabapentin! 🙀😹
Thyroid Hormone Receptor β1 and PGC1α Coordinately Regulate OPA1/MFN2‐Mediated Mitochondrial Fusion and UCP1‐Mediated Lipid Browning in ccRCC
Thyroid Hormone Receptor β1 and PGC1α Coordinately Regulate OPA1/MFN2‐Mediated Mitochondrial Fusion and UCP1‐Mediated Lipid Browning in ccRCC
Thyroid hormone receptor β1 (TRβ) downregulation correlates with poor prognosis in clear cell renal cell carcinoma (ccRCC). Restoration of TRβ and the peroxisome proliferator-activated receptor gamma coactivator 1-alpha suppresses tumor progression in ccRCC through Uncoupling protein 1 mediated tumor cell “slimming” and optic atrophy 1/mitofusin 2 dependent mitochondrial fusion.
Abstract
The abnormal accumulation of lipids is a hallmark of clear cell renal cell carcinoma (ccRCC). Both the thyroid hormone receptor β1 (TRβ) and peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC1α) are key regulators of mitochondrial function and lipid metabolism. However, their specific interaction and influence on ccRCC development and lipid accumulation remain poorly understood. This study identified genes jointly regulated by TRβ and PGC1α, which are implicated in lipid browning and mitochondrial fusion. Mechanistically, T3-activated TRβ interacts with PGC1α to transcriptionally upregulate PGC1α, UCP1, and mitochondrial fusion genes OPA1 and MFN2, thereby enhancing mitochondrial activity, promoting lipid utilization, and suppressing ccRCC progression. These results indicate that the mitochondrial and metabolic effects of TRβ in ccRCC are mediated through PGC1α expression and function. Activation of the TRβ/PGC1α through hormonal and pharmacological means may offer a promising therapeutic approach for ccRCC.
advanced.onlinelibrary.wiley.com
November 11, 2025 at 8:10 AM
Thyroid Hormone Receptor β1 and PGC1α Coordinately Regulate OPA1/MFN2‐Mediated Mitochondrial Fusion and UCP1‐Mediated Lipid Browning in ccRCC
Selenium helps protect the thyroid from oxidative stress and keeps hormone levels stable, promoting overall wellness. This simple daily habit offers an easy, natural way to boost thyroid function and long-term health.
November 11, 2025 at 6:40 AM
Selenium helps protect the thyroid from oxidative stress and keeps hormone levels stable, promoting overall wellness. This simple daily habit offers an easy, natural way to boost thyroid function and long-term health.
Brazil nuts are a powerful natural source of selenium, a vital mineral that plays a key role in maintaining a healthy thyroid. Studies show that eating just two Brazil nuts a day provides enough selenium to support hormone production, metabolism, and energy balance.
November 11, 2025 at 6:40 AM
Brazil nuts are a powerful natural source of selenium, a vital mineral that plays a key role in maintaining a healthy thyroid. Studies show that eating just two Brazil nuts a day provides enough selenium to support hormone production, metabolism, and energy balance.
is the thyroid the king of the glands
November 11, 2025 at 5:34 AM
is the thyroid the king of the glands
The normal range of TSH is 0.4-5.0. I am at .8 right now, but if it’s above 1.5 I do better with regulating my body temperature. I have thyroid nodules that stay stable, but I haven’t had a dose increase in years. I think he will increase it.
Then we can talk about my crappy bone density.
Then we can talk about my crappy bone density.
November 11, 2025 at 1:44 AM
The normal range of TSH is 0.4-5.0. I am at .8 right now, but if it’s above 1.5 I do better with regulating my body temperature. I have thyroid nodules that stay stable, but I haven’t had a dose increase in years. I think he will increase it.
Then we can talk about my crappy bone density.
Then we can talk about my crappy bone density.
my friend had her whole thyroid out (cancer, she’s fine now) and all she needs is synthroid!!!
November 11, 2025 at 1:37 AM
my friend had her whole thyroid out (cancer, she’s fine now) and all she needs is synthroid!!!
Interesting, I've long suspected thyroid issues for me but I never test out of range. I'm always at the low end of normal, yet I have all the symptoms of thyroid disregulation and literally everyone in my family has hypothyroidism and is on Synthroid
November 11, 2025 at 1:37 AM
Interesting, I've long suspected thyroid issues for me but I never test out of range. I'm always at the low end of normal, yet I have all the symptoms of thyroid disregulation and literally everyone in my family has hypothyroidism and is on Synthroid
Given my wife and my family histories, our kid is going to have the worse thyroid of all time lmao
November 11, 2025 at 1:34 AM
Given my wife and my family histories, our kid is going to have the worse thyroid of all time lmao
It really does. Tomorrow I see my endocrinologist and I’m going to ask for an increase in my thyroid meds, there is a sweet spot with those levels that lessens the attacks for me. I’m testing normal but the low end of normal right now.
November 11, 2025 at 1:33 AM
It really does. Tomorrow I see my endocrinologist and I’m going to ask for an increase in my thyroid meds, there is a sweet spot with those levels that lessens the attacks for me. I’m testing normal but the low end of normal right now.
Lenvatinib plus pembrolizumab for the Treatment of Patients With Non-BRAF mutated Anaplastic Thyroid Cancer: A single center, phase 2 clinical trial https://www.medrxiv.org/content/10.1101/2025.11.09.25339786v1
November 11, 2025 at 1:27 AM
Lenvatinib plus pembrolizumab for the Treatment of Patients With Non-BRAF mutated Anaplastic Thyroid Cancer: A single center, phase 2 clinical trial https://www.medrxiv.org/content/10.1101/2025.11.09.25339786v1
Are there people with treatment resistant thyroid disease? I’ve never heard of this
November 11, 2025 at 1:27 AM
Are there people with treatment resistant thyroid disease? I’ve never heard of this
watching shark tank and a woman claimed that western medicine couldn’t treat her thyroid disease. respectfully, lol
November 11, 2025 at 1:25 AM
watching shark tank and a woman claimed that western medicine couldn’t treat her thyroid disease. respectfully, lol
This story is both uniquely horrifying--this poor woman💔--and far too common.
Dr. Susan Baumgaertel at Seattle's Polyclinic Madison dismissed my thyroid cancer as menopause for 2+ yrs--she never even sent me to an endo--& it was Stage 3 when I ended up in the ER.
www.msn.com/en-ae/news/o...
Dr. Susan Baumgaertel at Seattle's Polyclinic Madison dismissed my thyroid cancer as menopause for 2+ yrs--she never even sent me to an endo--& it was Stage 3 when I ended up in the ER.
www.msn.com/en-ae/news/o...
MSN
www.msn.com
November 11, 2025 at 1:22 AM
This story is both uniquely horrifying--this poor woman💔--and far too common.
Dr. Susan Baumgaertel at Seattle's Polyclinic Madison dismissed my thyroid cancer as menopause for 2+ yrs--she never even sent me to an endo--& it was Stage 3 when I ended up in the ER.
www.msn.com/en-ae/news/o...
Dr. Susan Baumgaertel at Seattle's Polyclinic Madison dismissed my thyroid cancer as menopause for 2+ yrs--she never even sent me to an endo--& it was Stage 3 when I ended up in the ER.
www.msn.com/en-ae/news/o...
Until the ACA I was uninsurable due to pre-existing conditions.
Every time I changed jobs there was a 90 day period that my thyroid meds and MD visits weren't covered. I haven't had a thyroid since 1992.
The ACA changed all of that.
Every time I changed jobs there was a 90 day period that my thyroid meds and MD visits weren't covered. I haven't had a thyroid since 1992.
The ACA changed all of that.
November 11, 2025 at 1:15 AM
Until the ACA I was uninsurable due to pre-existing conditions.
Every time I changed jobs there was a 90 day period that my thyroid meds and MD visits weren't covered. I haven't had a thyroid since 1992.
The ACA changed all of that.
Every time I changed jobs there was a 90 day period that my thyroid meds and MD visits weren't covered. I haven't had a thyroid since 1992.
The ACA changed all of that.
If you work with #scRNAseq, #salivary, #thyroid or #mammary gland #organoids, or are interested in #irradiation and #Notch signaling, you might find this exciting! Our latest paper is now available in @embojournal.org! Check it out! Link below ✨
doi.org/10.1038/s443...
doi.org/10.1038/s443...
November 11, 2025 at 1:15 AM
If you work with #scRNAseq, #salivary, #thyroid or #mammary gland #organoids, or are interested in #irradiation and #Notch signaling, you might find this exciting! Our latest paper is now available in @embojournal.org! Check it out! Link below ✨
doi.org/10.1038/s443...
doi.org/10.1038/s443...
Iodine & Thyroid: The Vital Connection 🦋
The #Thyroid needs iodine to make #Hormones that regulate #Metabolism, Energy and #Mood.🚦
Low #Iodine leads to Fatigue, Weight Gain and Brain Fog 🥴
Are you getting enough for the whole body? 💖
myzenhaus.com/iodine-as-medicine
#WeightLoss #Supplements
The #Thyroid needs iodine to make #Hormones that regulate #Metabolism, Energy and #Mood.🚦
Low #Iodine leads to Fatigue, Weight Gain and Brain Fog 🥴
Are you getting enough for the whole body? 💖
myzenhaus.com/iodine-as-medicine
#WeightLoss #Supplements
November 11, 2025 at 12:45 AM
Iodine & Thyroid: The Vital Connection 🦋
The #Thyroid needs iodine to make #Hormones that regulate #Metabolism, Energy and #Mood.🚦
Low #Iodine leads to Fatigue, Weight Gain and Brain Fog 🥴
Are you getting enough for the whole body? 💖
myzenhaus.com/iodine-as-medicine
#WeightLoss #Supplements
The #Thyroid needs iodine to make #Hormones that regulate #Metabolism, Energy and #Mood.🚦
Low #Iodine leads to Fatigue, Weight Gain and Brain Fog 🥴
Are you getting enough for the whole body? 💖
myzenhaus.com/iodine-as-medicine
#WeightLoss #Supplements
Nasser is so sick from his thyroid condition that his skin has gone a very unhealthy waxy yellow pallor, and his eyes are pointing in different directions.
💔 Every hour feels like a battle for survival… Nasser’s medicine has completely run out, and his condition is worsening fast. We have no food and nothing left for our basic needs.
I urgently need $250 to get Nasser’s treatment and provide food for my children ❤️🩹
gofund.me/edd687b8
I urgently need $250 to get Nasser’s treatment and provide food for my children ❤️🩹
gofund.me/edd687b8
November 11, 2025 at 12:09 AM
Nasser is so sick from his thyroid condition that his skin has gone a very unhealthy waxy yellow pallor, and his eyes are pointing in different directions.
Bitch, my immune system decided to attack my pancreas, and my thyroid cells decided to mutate oncogenically, and there was nothing anyone could do about any of it "preventatively." We need real healthcare to address the real problems people like me have.
Rep. John McGuire: "We need to rethink healthcare in America. It needs to be a preventative healthcare system, not a reactive, put-a-bandaid-on system that we have...you cannot exercise your way out of bad nutrition. Eat right, exercise right, lead a healthy lifestyle, & maybe have early screenings"
November 10, 2025 at 11:57 PM
Bitch, my immune system decided to attack my pancreas, and my thyroid cells decided to mutate oncogenically, and there was nothing anyone could do about any of it "preventatively." We need real healthcare to address the real problems people like me have.
This is why I think the hypothesis that we're in a computer simulation is true, and its being run by a 15 year-old sadist with a thyroid condition.
November 10, 2025 at 11:36 PM
This is why I think the hypothesis that we're in a computer simulation is true, and its being run by a 15 year-old sadist with a thyroid condition.