#randomizedTrial
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epilepsia-open.bsky.social
Key point: A low dose of antiseizure medications may be started in adults with a new diagnosis of focal epilepsy of unknown etiology and low seizure frequency.
doi.org/10.1002/epi4...

#epilepsy #ILAE #efficacy #focalepilepsy #lowdose #monotherapy #newlydiagnosedepilepsy #randomizedtrial
March 4, 2025 at 3:36 PM
guyattgh.bsky.social
Anyone interested in determining the effect of a drug in a single patient by conducting a #RandomizedTrial in a that patient – an N of 1 trial – will find this step-by-step guide enormously useful.

www.cmaj.ca/content/139/...
A clinician's guide for conducting randomized trials in individual patients
In determining optimal treatment for a patient conventional trials of therapy are susceptible to bias. Large-scale randomized trials can provide only a partial guide and have not been or cannot be car...
www.cmaj.ca
November 6, 2025 at 11:57 AM
guyattgh.bsky.social
The ground-breaking #NEJM #randomizedTrial suggests that every #surgery patient at substantial #bleeding risk should receive #tranexamicAcid: 24% #RelativeRisk reduction in serious bleeding.

www.nejm.org/doi/full/10....
Tranexamic Acid in Patients Undergoing Noncardiac Surgery | NEJM
Perioperative bleeding is common in patients undergoing noncardiac surgery. Tranexamic acid is an antifibrinolytic drug that may safely decrease such bleeding. We conducted a trial involving patien...
www.nejm.org
October 28, 2025 at 5:19 AM
amm-journal.org
Randomized, waitlist-controlled trial of #Cordycepssinensis mycelium culture extract (#Cs4) for #longCOVID patients in Hong Kong.

Read More: amm-journal.org/index.php/20...

#randomizedtrial #modifiedCOVID19 #YorkshireRehabilitationScale #C19YRSm @scienceopen.bsky.social
Randomized, waitlist-controlled trial of Cordyceps sinensis mycelium culture extract (Cs4) for long COVID patients in Hong Kong
Cordyceps sinensis mycelium culture extract (Cs4) were assessed for alleviating long COVID symptoms. In this randomized trial 110 participants were assigned to receive Cs4 (55 participants) or were wa...
amm-journal.org
March 10, 2025 at 11:48 AM