Got my pneumococcal and second shingles vaccines today and I'm feeling a bit hit-by-truckish this evening. Worth it though. Eat shit, RFK
November 12, 2025 at 2:48 AM
Got my pneumococcal and second shingles vaccines today and I'm feeling a bit hit-by-truckish this evening. Worth it though. Eat shit, RFK
If one must spend their Friday evening creating pneumococcal vaccines slides, then one should also put on OG @toolmusic.bsky.social on their speakers and rock out.
November 8, 2025 at 12:36 AM
If one must spend their Friday evening creating pneumococcal vaccines slides, then one should also put on OG @toolmusic.bsky.social on their speakers and rock out.
I got the pneumococcal as well today and no side effects. The second shingles shot was bad last year but I was thrilled to get it (brand new study shows increased dementia risk after a second shingles infection!)
November 12, 2025 at 3:14 AM
I got the pneumococcal as well today and no side effects. The second shingles shot was bad last year but I was thrilled to get it (brand new study shows increased dementia risk after a second shingles infection!)
Yep and flu and shingles and pneumococcal. It’s across all adult vaccinations not just Covid specifically.
November 6, 2025 at 3:54 PM
Yep and flu and shingles and pneumococcal. It’s across all adult vaccinations not just Covid specifically.
If 1% of ED LPs end up being for Pneumo, and 1% of Pneumo in adults is R, you will do 10,000 vanco courses for every 1 patient with CTX-R pneumococcal meningitis. That will definitely cause a large amount of AKIs and VREs.
In LA, we recommend NOT adding vanco until LP CSF WBC/% PMN known.
In LA, we recommend NOT adding vanco until LP CSF WBC/% PMN known.
November 5, 2025 at 3:52 PM
If 1% of ED LPs end up being for Pneumo, and 1% of Pneumo in adults is R, you will do 10,000 vanco courses for every 1 patient with CTX-R pneumococcal meningitis. That will definitely cause a large amount of AKIs and VREs.
In LA, we recommend NOT adding vanco until LP CSF WBC/% PMN known.
In LA, we recommend NOT adding vanco until LP CSF WBC/% PMN known.
Pneumococcal vaccination under age 65 is based on risk factors. I personally have had it and haven't had pneumonia since, whereas previously I had pneumonia every year or two, and I have to say I'm a big fan, but it's up to you and your doctor.
October 30, 2025 at 10:01 PM
Pneumococcal vaccination under age 65 is based on risk factors. I personally have had it and haven't had pneumonia since, whereas previously I had pneumonia every year or two, and I have to say I'm a big fan, but it's up to you and your doctor.
"The pneumococcal vaccine protects against .... pneumococcus. Pneumococcus is a common cause of pneumonia (a lung infection), as well as other serious infections. The vaccine prepares your immune system to recognize and fight pneumococcal bacteria. .."
jamanetwork.com/journals/jam...
jamanetwork.com/journals/jam...
What Do I Need to Know About the Pneumococcal Pneumonia Vaccine?
This JAMA Internal Medicine Patient Page describes how the pneumococcal pneumonia vaccine works, who should get it, and its benefits and side effects.
jamanetwork.com
October 29, 2025 at 9:17 PM
"The pneumococcal vaccine protects against .... pneumococcus. Pneumococcus is a common cause of pneumonia (a lung infection), as well as other serious infections. The vaccine prepares your immune system to recognize and fight pneumococcal bacteria. .."
jamanetwork.com/journals/jam...
jamanetwork.com/journals/jam...
PP in the study is Pneumococcal Pneumonia
ACP is All Cause Pneumonia
The study was to see if an immune response resulted in actually immunity. The trad def of vaccine required it to produce immunity. The new (2020 definition) of vaccine requires only an immune response.
(Cont
ACP is All Cause Pneumonia
The study was to see if an immune response resulted in actually immunity. The trad def of vaccine required it to produce immunity. The new (2020 definition) of vaccine requires only an immune response.
(Cont
October 29, 2025 at 3:54 PM
PP in the study is Pneumococcal Pneumonia
ACP is All Cause Pneumonia
The study was to see if an immune response resulted in actually immunity. The trad def of vaccine required it to produce immunity. The new (2020 definition) of vaccine requires only an immune response.
(Cont
ACP is All Cause Pneumonia
The study was to see if an immune response resulted in actually immunity. The trad def of vaccine required it to produce immunity. The new (2020 definition) of vaccine requires only an immune response.
(Cont
Every year in Europe:
• Flu causes millions of infections & tens of thousands of deaths
• RSV leads to ~250 000 hospitalisations in children & 160 000 in older adults
• SARS-CoV-2 continues to circulate year-round
• Pneumococcal pneumonia remains a major cause of hospitalisation among older adults
• Flu causes millions of infections & tens of thousands of deaths
• RSV leads to ~250 000 hospitalisations in children & 160 000 in older adults
• SARS-CoV-2 continues to circulate year-round
• Pneumococcal pneumonia remains a major cause of hospitalisation among older adults
October 28, 2025 at 10:21 AM
Every year in Europe:
• Flu causes millions of infections & tens of thousands of deaths
• RSV leads to ~250 000 hospitalisations in children & 160 000 in older adults
• SARS-CoV-2 continues to circulate year-round
• Pneumococcal pneumonia remains a major cause of hospitalisation among older adults
• Flu causes millions of infections & tens of thousands of deaths
• RSV leads to ~250 000 hospitalisations in children & 160 000 in older adults
• SARS-CoV-2 continues to circulate year-round
• Pneumococcal pneumonia remains a major cause of hospitalisation among older adults
I had whopping cough when I was 7. No whop sound but correct diagnosis and such hard and heavy coughing I blew a hole in my left lung. That was followed the next year with emphysema.
Now there are vaccines for whopping cough and the pneumococcal vaccine, so no kid has to go through what I did.
Now there are vaccines for whopping cough and the pneumococcal vaccine, so no kid has to go through what I did.
October 27, 2025 at 2:59 PM
I had whopping cough when I was 7. No whop sound but correct diagnosis and such hard and heavy coughing I blew a hole in my left lung. That was followed the next year with emphysema.
Now there are vaccines for whopping cough and the pneumococcal vaccine, so no kid has to go through what I did.
Now there are vaccines for whopping cough and the pneumococcal vaccine, so no kid has to go through what I did.
Metastatic melanoma: Similar benefit was observed (HR 0.37; p = 0.0048) and longer progression-free survival.
No benefit was seen with influenza or pneumococcal vaccination, implying the effect is unique to the mRNA platform.
No benefit was seen with influenza or pneumococcal vaccination, implying the effect is unique to the mRNA platform.
October 25, 2025 at 1:42 PM
Metastatic melanoma: Similar benefit was observed (HR 0.37; p = 0.0048) and longer progression-free survival.
No benefit was seen with influenza or pneumococcal vaccination, implying the effect is unique to the mRNA platform.
No benefit was seen with influenza or pneumococcal vaccination, implying the effect is unique to the mRNA platform.
This is in line with a previouis study from this group. www.sciencedirect.co...
The cause of PP is not known and may not be any pneumococcal strain not included in the vaccines.
6/9
The cause of PP is not known and may not be any pneumococcal strain not included in the vaccines.
6/9
Evaluating clinical effectiveness and impact of anti-pneumococcal vaccination in adults after universal childhood PCV13 implementation in Catalonia, 2017–2018
At present, because of indirect effects derived from routine childhood immunisation, clinical benefits vaccinating adults with the 23-valent pneumococ…
www.sciencedirect.com
October 26, 2025 at 9:12 AM
This is in line with a previouis study from this group. www.sciencedirect.co...
The cause of PP is not known and may not be any pneumococcal strain not included in the vaccines.
6/9
The cause of PP is not known and may not be any pneumococcal strain not included in the vaccines.
6/9
In short, people who got an mRNA vaccine within 100 days of starting their immunotherapy lived for nearly twice as long in this cohort, and had nearly double the likelihood of living 3 years. This effect was restricted to mRNA COVID-19 vaccines. The effect of Pfizer vs. Moderna was similar.
October 25, 2025 at 5:53 PM
In short, people who got an mRNA vaccine within 100 days of starting their immunotherapy lived for nearly twice as long in this cohort, and had nearly double the likelihood of living 3 years. This effect was restricted to mRNA COVID-19 vaccines. The effect of Pfizer vs. Moderna was similar.
October 23, 2025 at 10:05 AM
Shingles vaccine associated with good things in older age, when compared to people who had pneumococcal vaccine (so not just about vaccine seeking behaviour).
I'll look forward to seeing the paper when it comes out.
I'll look forward to seeing the paper when it comes out.
October 21, 2025 at 11:39 PM
Shingles vaccine associated with good things in older age, when compared to people who had pneumococcal vaccine (so not just about vaccine seeking behaviour).
I'll look forward to seeing the paper when it comes out.
I'll look forward to seeing the paper when it comes out.
Relative to pneumococcal vaccination, shingles vaccination was tied to a lower risk of vascular dementia (50%), blood clots (27%), heart attack or stroke (25%), and death (21%). The study authors said that the findings suggest the shingles vaccine can prevent both infection and its complications.
October 21, 2025 at 2:36 AM
Relative to pneumococcal vaccination, shingles vaccination was tied to a lower risk of vascular dementia (50%), blood clots (27%), heart attack or stroke (25%), and death (21%). The study authors said that the findings suggest the shingles vaccine can prevent both infection and its complications.
Vaccines control entirely DIFFERENT diseases that sanitation does little for.
Person-to-person, direct contact, & respiratory diseases:
Measles
Mumps
Rubella
Whooping cough
Diphtheria
Influenza
COVID-19
Hepatitis B
HPV
RSV
Meningococcal disease
Varicella
Pneumococcal pneumonia
4/
Person-to-person, direct contact, & respiratory diseases:
Measles
Mumps
Rubella
Whooping cough
Diphtheria
Influenza
COVID-19
Hepatitis B
HPV
RSV
Meningococcal disease
Varicella
Pneumococcal pneumonia
4/
October 18, 2025 at 1:00 AM
Vaccines control entirely DIFFERENT diseases that sanitation does little for.
Person-to-person, direct contact, & respiratory diseases:
Measles
Mumps
Rubella
Whooping cough
Diphtheria
Influenza
COVID-19
Hepatitis B
HPV
RSV
Meningococcal disease
Varicella
Pneumococcal pneumonia
4/
Person-to-person, direct contact, & respiratory diseases:
Measles
Mumps
Rubella
Whooping cough
Diphtheria
Influenza
COVID-19
Hepatitis B
HPV
RSV
Meningococcal disease
Varicella
Pneumococcal pneumonia
4/
A 52-year-old man with a history of splenectomy and hypogammaglobulinemia after CAR T-cell therapy for lymphoma 3 years earlier was admitted with septic shock. Encapsulated diplococci were seen in 20% of neutrophils. Read the full case details: nej.md/4oap9GL
#MedSky #IDSky
#MedSky #IDSky
October 18, 2025 at 4:05 PM
A 52-year-old man with a history of splenectomy and hypogammaglobulinemia after CAR T-cell therapy for lymphoma 3 years earlier was admitted with septic shock. Encapsulated diplococci were seen in 20% of neutrophils. Read the full case details: nej.md/4oap9GL
#MedSky #IDSky
#MedSky #IDSky
Disease modulation by TIV vaccination during secondary pneumococcal infections in influenza-infected mice. https://www.biorxiv.org/content/10.1101/2025.10.16.682853v1
October 17, 2025 at 8:16 PM
Disease modulation by TIV vaccination during secondary pneumococcal infections in influenza-infected mice. https://www.biorxiv.org/content/10.1101/2025.10.16.682853v1
This news was very sad to hear.
Pneumonia from any cause is very serious in older individuals. This is why we recommend pneumococcal vaccines for everyone 60 and over and RSV, Flu and COVID vaccines to prevent viral causes of Pneumonia.
R.I.P #DianeKeaton
www.nbcnews.com/pop-culture/...
Pneumonia from any cause is very serious in older individuals. This is why we recommend pneumococcal vaccines for everyone 60 and over and RSV, Flu and COVID vaccines to prevent viral causes of Pneumonia.
R.I.P #DianeKeaton
www.nbcnews.com/pop-culture/...
Diane Keaton died of pneumonia, her family confirms, thanking fans for 'love and support'
"Any donations in her memory to a local food bank or an animal shelter would be a wonderful and much appreciated tribute to her," her family said.
www.nbcnews.com
October 16, 2025 at 5:19 PM
This news was very sad to hear.
Pneumonia from any cause is very serious in older individuals. This is why we recommend pneumococcal vaccines for everyone 60 and over and RSV, Flu and COVID vaccines to prevent viral causes of Pneumonia.
R.I.P #DianeKeaton
www.nbcnews.com/pop-culture/...
Pneumonia from any cause is very serious in older individuals. This is why we recommend pneumococcal vaccines for everyone 60 and over and RSV, Flu and COVID vaccines to prevent viral causes of Pneumonia.
R.I.P #DianeKeaton
www.nbcnews.com/pop-culture/...
@bradspellberg.bsky.social
Hi Brad, I’d like to hear your opinion on the optimal antibiotic approach for pneumococcal pneumonia with bacteremia — do you favor combination therapy (β-lactam plus macrolide) or β-lactam monotherapy in these cases?
Hi Brad, I’d like to hear your opinion on the optimal antibiotic approach for pneumococcal pneumonia with bacteremia — do you favor combination therapy (β-lactam plus macrolide) or β-lactam monotherapy in these cases?
October 16, 2025 at 8:51 PM
@bradspellberg.bsky.social
Hi Brad, I’d like to hear your opinion on the optimal antibiotic approach for pneumococcal pneumonia with bacteremia — do you favor combination therapy (β-lactam plus macrolide) or β-lactam monotherapy in these cases?
Hi Brad, I’d like to hear your opinion on the optimal antibiotic approach for pneumococcal pneumonia with bacteremia — do you favor combination therapy (β-lactam plus macrolide) or β-lactam monotherapy in these cases?
Yeah. I have auto immune disease (and get strong reactions to vaxes) and already have regular covid and flu vax and this year had whooping cough etc vax too. Next year baby grandson goes to childcare so I'll get RSV vax then pneumococcal vax then Shingles. Over time.
October 17, 2025 at 9:57 AM
Yeah. I have auto immune disease (and get strong reactions to vaxes) and already have regular covid and flu vax and this year had whooping cough etc vax too. Next year baby grandson goes to childcare so I'll get RSV vax then pneumococcal vax then Shingles. Over time.
Just got my 11th covid shot, my yearly flu shot, and my first Pneumococcal shot (I hit 65 this year). All free.
October 15, 2025 at 10:19 PM
Just got my 11th covid shot, my yearly flu shot, and my first Pneumococcal shot (I hit 65 this year). All free.
The Pneumococcal vaccine has also been linked to reduced dementia outcomes. It’s part of the schedule and almost lifelong
While many things can cause pneumonia, this one goes for the most likely suspects
info.health.nz/immunisation...
While many things can cause pneumonia, this one goes for the most likely suspects
info.health.nz/immunisation...
info.health.nz
October 13, 2025 at 8:18 PM
The Pneumococcal vaccine has also been linked to reduced dementia outcomes. It’s part of the schedule and almost lifelong
While many things can cause pneumonia, this one goes for the most likely suspects
info.health.nz/immunisation...
While many things can cause pneumonia, this one goes for the most likely suspects
info.health.nz/immunisation...
Weekend Briefing for October 11, 2025:
New Images in Clinical Medicine: Pneumococcal Sepsis in Asplenia and Hypogammaglobulinemia nej.md/4oap9GL
Three New Perspectives:
1️⃣ Digital Treatment to Reduce Global Tobacco Use nej.md/4nKq29e
#MedSky
New Images in Clinical Medicine: Pneumococcal Sepsis in Asplenia and Hypogammaglobulinemia nej.md/4oap9GL
Three New Perspectives:
1️⃣ Digital Treatment to Reduce Global Tobacco Use nej.md/4nKq29e
#MedSky
October 11, 2025 at 1:01 PM
Weekend Briefing for October 11, 2025:
New Images in Clinical Medicine: Pneumococcal Sepsis in Asplenia and Hypogammaglobulinemia nej.md/4oap9GL
Three New Perspectives:
1️⃣ Digital Treatment to Reduce Global Tobacco Use nej.md/4nKq29e
#MedSky
New Images in Clinical Medicine: Pneumococcal Sepsis in Asplenia and Hypogammaglobulinemia nej.md/4oap9GL
Three New Perspectives:
1️⃣ Digital Treatment to Reduce Global Tobacco Use nej.md/4nKq29e
#MedSky