#neutralization
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Potent neutralization of Marburg virus by a vaccine-elicited antibody

www.nature.com/articles/s41...
Potent neutralization of Marburg virus by a vaccine-elicited antibody - Nature
Nature - Potent neutralization of Marburg virus by a vaccine-elicited antibody
www.nature.com
November 12, 2025 at 6:26 PM
sailorrooscout.bsky.social
ONLY five to nine out of a panel of 337 strains were resistant to some extent at all, and the antibody possessed a nearly unprecedented breadth of neutralization. It also performed well against viruses ALREADY RESISTANT to other antibodies- neutralizing nearly 80% of viruses that evaded VRC01.
Fig. 1: Large-scale isolation of mAbs from HIV-1 elite neutralizers. Fig. 2: bnAbs coevolved with overlapping specificity for the CD4bs. Fig. 3: 04_A06 demonstrates marked neutralizing potency and breadth.
November 12, 2025 at 5:09 PM
insideukraine.bsky.social
🔵 🤯  Another neutralization of a Russian ambush drone

This time, the Ukrainian soldiers approached it from behind and cut the fiber-optic cable
November 10, 2025 at 12:02 PM
labwaggoner.bsky.social
Potent neutralization of Marburg virus by a vaccine-elicited antibody @nature.com @hhmi.org @veeslerlab.bsky.social @virbiotechnology.bsky.social
www.nature.com/articles/s41...
November 12, 2025 at 5:49 PM
cryoempapers.bsky.social
Potent neutralization of Marburg virus by a vaccine-elicited antibody pubmed.ncbi.nlm.nih.gov/41225006/ #cryoem
November 13, 2025 at 4:23 PM
macroliter.bsky.social
🧪 🦠 Prefusion structure, evasion and neutralization of HSV-1 glycoprotein B www.nature.com/articles/s41...
Prefusion structure, evasion and neutralization of HSV-1 glycoprotein B - Nature Microbiology
Cryo-EM structures of the stabilized prefusion conformation of the glycoprotein B ectodomain—the HSV-1 entry machine—identify a prefusion-specific neutralizing antibody and reveal how prefusion glycop...
www.nature.com
November 8, 2025 at 3:37 AM
wordsfromtaiwan.bsky.social
Social media functions as a "distorted mirror," explains @pumashen.bsky.social, e.g. 3% of accounts generate 33% of posts; 1% of online communities are responsible for 74% of conflict; 0.1% of users drive 80% of #disinformation.

The strategic response is to neutralize methods of mass amplification.
4. Conclusion and Recommendations The fundamental threat of autocratic information operations is rooted not in content veracity, but in the structural distortion created by asymmetric amplification. These campaigns, which often leverage state resources to deploy mechanisms like content farms and microtargeting, effectively mimic genuine domestic discourse, substituting authentic democratic voices with foreign influence. Social media functions as a "distorted mirror," where a minuscule fraction of actors (e.g., 3% of accounts generate 33% of posts; 1% of online communities are responsible for 74% of online conflict; 0.1% of users driving 80% of disinformation) generates an illusion of consensus or extreme polarization, thereby degrading the civic space and reducing moderate engagement. Therefore, the strategic response must pivot from content verification to the detection and neutralization of these methods of mass amplification. Policy must focus on dismantling the structural architecture of foreign interference and promoting media literacy that encourages citizens to benchmark online narratives against offline, real-world complexity and focus on primary and nuanced information. Sources: Claire E. Robertson, “Inside the funhouse mirror factory: How social media distorts perceptions of norms”, Current Opinion in Psychology (2024) Chris Bail, Breaking the Social Media Prism: How to Make Our Platforms Less Polarizing (Princeton: Princeton University Press, 2021)
November 13, 2025 at 9:58 AM
natmicrobiol.nature.com
#NewResearch

Prefusion structure, evasion and neutralization of HSV-1 glycoprotein B

#microsky

www.nature.com/articles/s41...
Prefusion structure, evasion and neutralization of HSV-1 glycoprotein B - Nature Microbiology
Cryo-EM structures of the stabilized prefusion conformation of the glycoprotein B ectodomain—the HSV-1 entry machine—identify a prefusion-specific neutralizing antibody and reveal how prefusion glycop...
www.nature.com
November 7, 2025 at 11:17 AM
dropsitenews.com
🇱🇧 U.S. Envoy Tom Barrack: “Lebanon Is a Failed State — the State Is Hezbollah”

At Bahrain’s Manama Dialogue, U.S. envoy Tom Barrack delivered an openly interventionist pitch urging Lebanon to abandon its resistance and normalize with Israel. “The Lebanese talk and talk — they charm you into...
and normalize with Israel. “The Lebanese talk and talk — they charm you into submission,” he said, before calling Lebanon “a failed state.” Barrack claimed the “French-mandated confessional system” had collapsed, that the country’s banks were looted and its institutions broken, and that “the state is Hezbollah.” He recited figures — “40 thousand soldiers making $2,200 a month, versus 60 thousand in the army making $275.” Hezbollah, he said, provides water, power, and education while the state offers nothing. He called disarming Hezbollah unrealistic — “you can’t tell Lebanon to forcibly disarm one of its political parties” — but pressed for its “neutralization” through integration and border deals with Israel. Washington’s line, he said, is that “Israel is ready to make border and boundary agreements with all its neighbors, and it owes America a favor.” He invoked Trump’s June 21 B-2 bomber deployment to support Israel as proof Israel will act in a way that’s supportive of American diplomacy in the region. Barrack mocked Lebanon’s ban on contact with Israel: “You can’t even say the word ‘Israel.’ They still call it ‘the south of the Litani.’ What era are we living in?” He urged Beirut to “go from Beirut to Tel Aviv, have that conversation on the Blue Line… in four months you could end all of this.” Turning to Lebanon’s leadership, he praised a few by name — President Aoun, Prime Minister Nouf, Speaker Berri — but dismissed them as “dinosaurs.” “They’re trying,” he said, “but you’ve got to go from the pay phone to Starlink — not pay phone to home phone, not to cell phone. Straight to Starlink.” He ended by warning that time is running out: “Israel every day is bombing the south because you still have thousands of rockets and missiles threatening it. After October 7, Israel has said it will defend its borders and enforce them in its own right. Put your weapons down, Hezbollah, and we will not have a problem.”
November 4, 2025 at 7:46 PM
oosenhormiyagi.bsky.social
At some point, the population will react. They will do what needs to be done. The neutralization of state agents. Starting with the leaders. 😠
November 1, 2025 at 11:09 AM
forbin17.bsky.social
Great neutralization
October 31, 2025 at 11:07 AM
isabelott.bsky.social
Jordi Casals’ infection - survivable only through emergency convalescent serum treatment from a recovered nurse (Lily Pinneo - her Lassa infection produced the “LP” strain), along with the fatal infection of his technician, Juan Roman, are better-known parts of this story, but still chilling (3/3)
I learned of this Monday, when Wil Downs assembled the staff for a meeting. He described Jordi Casals as suffering from a severe illness, characterized mainly by high fever of unknown origin, a low white cell count, pharyngitis and unusually severe muscle pains, affecting the leg muscles. Wil Downs, making the tentative diagnosis of Lassa fever, was in favor of giving immediately immune plasma from Lily Pinneo, known to contain protecting neutraling antibodies from the neutralization tests performed in the Vero cell cultures. But the physician in charge would not hear of this specifc treatment. He wanted to establish first a definitive diagnosis of Lassa fever by isolation of the Lassa virus from JC. That would take at least 96 hours. Wil Downs, in compliance, arranged for a messenger service of specimens from JC, Jimmy Washington, residing in NY & a long-time technician of JC, thereafter brought me blood specimens, throat washings as well as urine samples from the patient. This was carried out M-W, and in the meantime, JC was golng down-hill rapidly. On Wed, we had another staff meeting… We were unanimously in favor of therapy with immune plasma from Lily Pinneo. Jordi Casals was dying. Lily Pinneo, reconvalescing from Lassa fever at home, was summoned and reached New York within hours by plane. The very same evening, an infusion of immune plasma was initiated…& continued during the night. At the same time. I was monitoring the virema (virus in the blood) of JC by virus isolations in Vero cell cultures at the Yale Arbovirus Research Unit. The results were as follows: while the blood specimens, up to and including June 18, 1969, contained Lassa virus, the specimens as of 48 hours following therapy with immune plasma were free of Lassa virus. However, throat washings and urine samples remained Lassa virus-positive for many more weeks. While clinically JC was recovering, he continued to be contaglous. He was, however, released from the Hospital and was reconvalescing at home. By the middle of July 1969, all shedding of Lassa virus had ceased. All laboratory reports were signed out as negative by me. To our great joy and relief Jordi Casals had almost certainly been saved specifically by the timely administration of antibody derived from Lily Pinneo. Juan Roman, a young laboratory technician of Jordi Casals, was not as lucky. He acquired a Lassa virus laboratory infection verified by Lassa virus isolation in Vero cell cultures from autopsy material in a mysterious way and months later, when nobody was thinking of laboratory infections anymore. He developed a severe cold - just during the week of Thanksgiving - but unfortunately, insisted on carrying through plans to visit relatives in another state… He died there on the weekend following … Following this second laboratory infection, all experiments involving work with live Lassa virus were stopped at YARU, but continued in the high security facilities at the CDC, and at Porton Down, Wiltshire, England. …Lassa fever is described in the nineties as potentially dangerous Internationally, since it is present in small number of cases in West and Central Africa and could possibly be exported to Europe and North America. Highly fatal in epidemics. It is spread epidemiologically from a wild rodent reservoir of Lassa virus…Following recovery, there is natural immunity, probably lasting. At present, the only intervention available is rodent control, quarantine. disinfection of patient's excreta, and therapy with plasma and ribavirin. The political will for potential eradicability by the International Task Force for Disease Eradication is ascertained as "Low". Max Theller (1899-1972) warned me: "Sonja, watch out that the Lassa virus is not going to be stolen from you.” Incredible thought! He advised me to publish an "advance summary” in Nature Moreover, he said: Lassa virus made YARU" (Yale Arbovirus Research Unit), and he gave me the nickname: "The Late Bloomer."
November 2, 2025 at 6:22 PM
marcveld.bsky.social
Long-term neutralization capacity of vaccine and breakthrough infection induced SARS-CoV-2 specific antibodies against omicron subvariants BA.2, XBB.1.5, and JN.1

Boosters and infectons induce high level neutralising antibodies against subvariants

www.sciencedirect.co...
1/10
Long-term neutralization capacity of vaccine and breakthrough infection induced SARS-CoV-2 specific antibodies against omicron subvariants BA.2, XBB.1.5, and JN.1
The long-term effectiveness of COVID-19 vaccines remains a critical area of study, especially with the emergence of new SARS-CoV-2 subvariants. In thi…
www.sciencedirect.com
October 30, 2025 at 1:51 PM
utopia-defer.red
"they're incompetent, stupid, and massively unpopular"
The same day — August 3, 1922 — dealt a coup de grâce to municipal socialism in Milan. On the heels of a nationwide general strike in opposition to Fascist violence, squads of Blackshirts stormed and occupied Milan’s Palazzo Marino. On August 4, the prefect formally dismissed Mayor Filippetti and installed Count Ferdinando Lalli as prefectural commissioner. Milan’s Socialist administration was effectively dissolved. That evening, Fascist squads mounted their latest siege on the Milan offices of Socialist daily Avanti!, burning the building and smashing its presses. By nightfall, six were dead and dozens wounded. The neutralization of these Socialist municipalities was not incidental: it was integral to the momentum that propelled and consolidated the Fascist movement. By converting Socialist strongholds into administrative jurisdictions, the Italian state integrated Fascist demands to transform local governments from bases of working-class power into nodes of state control. Each success propelled further conquests, hardening Fascist cadres, normalizing street violence and commissariamento, and winning over hesitant elites. From the perspective of Fascism’s coalescence, the war on Socialist municipalities converted violent Fascist spectacle into bases of support. The bastions of municipal socialism built by the labor movement of the biennio rosso were toppled in two years’ time. To historians, those years are known as the biennio nero — the two black years that catapulted Benito Mussolini’s Fascists to power — soon inaugurating a twenty-year regime.
October 30, 2025 at 4:09 PM
handle.invalid
WordPress Contact Form CFDB7 (≤1.3.2) hit by CRITICAL pre-auth SQL injection & PHP object injection. Disable plugin or apply WAF rules until patched. High risk for web admins! https://radar.offseq.com/threat/cve-2025-4665-cwe-89-improper-neutralization-of-sp-5cca9eab #OffSeq #WordPress #VulnAlert
Security threat visualization
October 29, 2025 at 1:31 AM
tjeremy.com
Cash learned beachball neutralization techniques from Claudio

#AEWCollision 🤼‍♂️
October 26, 2025 at 1:38 AM
andrewchak.bsky.social
. @andriypzag.bsky.social convincingly argued that the New Theory of Victory Should be Strategic Neutralization:
build a resilient 🇺🇦 that withstands pressure militarily and economically until the #ruscist empire collapses under its own weight.
8/10 carnegieendowment.org/research/202...
October 24, 2025 at 8:43 AM
theotherspeakman.bsky.social
Supernatural Investigation & Neutralization Squad (SIN Squad) has one job: confront the spectres committing crimes post-mortem, and get them to stop by any means necessary.

The intangible cannot be imprisoned by any mortal means.
October 23, 2025 at 10:08 AM
taliajane.bsky.social
do not use “diversity of tactics” to defend co-option and self-neutralization. bsky.app/profile/tali...
taliajane.bsky.social talia jane ❤️‍🔥 @taliajane.bsky.social · Oct 14
it is no wonder that 50501, a movement of radlibs who are very upset but don’t want to get in trouble, would be boosting superficial activism.

superficial activism has its place, but if that place is front and center, it kills whatever movement it is skimming off the top of.
October 15, 2025 at 12:04 AM
morgenb.bsky.social
The 2008 video of Sen. Booker convincing a room of zionists that African American leaders and politicians can be swayed to the "Jewish cause" is indicative of how zionists rely on our voices and reactions in public. This is why the neutralization of social media has become priority.
October 15, 2025 at 5:23 PM
aneternalenigma.bsky.social
To address a very viral misinformation post going around the Dead Bird Site, there is no way the viewership neutralization cap is 2 streams. Twitch's own Stream Together product allows up to four streamers to stream together. It makes no sense Twitch would cannibalize everyone who watched all four.
October 13, 2025 at 11:58 PM
cyclesam.bsky.social
How can we not mention Magdeleine Vallières's victory at the World Championships #kigali2025 ? She took advantage of the neutralization of the favorites and managed to get to the front of the race 💥
#procycling
October 10, 2025 at 5:29 PM
angierasmussen.bsky.social
Since cross-reactive antibodies to N1 are so cross-reactive that they impact disease severity, they will show up as positive on even the functional assays that go beyond binding to look at virus neutralization—microneutralization & HAI. For H5N1 I think HAI is better.
October 9, 2025 at 11:38 AM
katherinestiles.org
▫️ #HIV ▫️ #MedSky ▫️
Antibody discovered that blocks almost all known HIV variants in neutralization assays
Antibody discovered that blocks almost all known HIV variants in neutralization assays
An international research team led by the University of Cologne has discovered an antibody that could advance the fight against HIV. The newly identified antibody 04_A06 proved to be particularly effe...
medicalxpress.com
October 7, 2025 at 9:41 AM
ferl67.bsky.social
Antibody discovered that blocks almost all known HIV variants in neutralization assays medicalxpress.com/news/2025-10... via @medical_xpress
Antibody discovered that blocks almost all known HIV variants in neutralization assays
An international research team led by the University of Cologne has discovered an antibody that could advance the fight against HIV. The newly identified antibody 04_A06 proved to be particularly effe...
medicalxpress.com
October 7, 2025 at 1:24 AM