That quote always struck me as weird.
Sea urchin lives aren't very eventful so I could see gastrulation being the most important part, but those of us chordates have at least neurulation competing with it, seems weird to knock that just because urchins.
Sea urchin lives aren't very eventful so I could see gastrulation being the most important part, but those of us chordates have at least neurulation competing with it, seems weird to knock that just because urchins.
November 14, 2025 at 11:55 PM
That quote always struck me as weird.
Sea urchin lives aren't very eventful so I could see gastrulation being the most important part, but those of us chordates have at least neurulation competing with it, seems weird to knock that just because urchins.
Sea urchin lives aren't very eventful so I could see gastrulation being the most important part, but those of us chordates have at least neurulation competing with it, seems weird to knock that just because urchins.
Our PhD student Šárka is now giving a chalk-talk presentation on her Prickle and neurulation work in front of her fellow students — and she is doing great! Go, Šárka! 🐸💪
#MUNI #PhDretreat #Xenopus #frogpower
#MUNI #PhDretreat #Xenopus #frogpower
November 13, 2025 at 5:32 PM
Our PhD student Šárka is now giving a chalk-talk presentation on her Prickle and neurulation work in front of her fellow students — and she is doing great! Go, Šárka! 🐸💪
#MUNI #PhDretreat #Xenopus #frogpower
#MUNI #PhDretreat #Xenopus #frogpower
Satheeja Santhi Velayudhan & co describe dynamic tension-dependent localisation of Diversin, a protein that regulates planar cell polarity signalling & apical constriction during Xenopus neurulation. 🐸
doi.org/10.1242/bio....
doi.org/10.1242/bio....
October 20, 2025 at 11:06 AM
Satheeja Santhi Velayudhan & co describe dynamic tension-dependent localisation of Diversin, a protein that regulates planar cell polarity signalling & apical constriction during Xenopus neurulation. 🐸
doi.org/10.1242/bio....
doi.org/10.1242/bio....
While I'm not at the NHM, I have read Scott Gilbert's book on embryology, and I'd guess it's a side effect of neurulation (the formation of the neural tube that defines chordates), and the associated migration of neural crest cells.
September 5, 2025 at 6:17 PM
While I'm not at the NHM, I have read Scott Gilbert's book on embryology, and I'd guess it's a side effect of neurulation (the formation of the neural tube that defines chordates), and the associated migration of neural crest cells.
Preprint alert! Just from the oven, the adventures of a young theoretical biophysicist (Santi Bosch) in a usually strictly wet lab (BCDN): how is it that extreme forces in amniotes primary neurulation do not break the highly dynamic neuroepithelium apart?
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Mechanical conditions preventing live cell extrusion during primary neurulation in amniotes
During primary neurulation in amniote embryos, the neural plate gives rise to the neural tube in a process requiring the coordination of forces at different scales throughout a geometrically complex t...
www.biorxiv.org
August 12, 2025 at 9:44 PM
Preprint alert! Just from the oven, the adventures of a young theoretical biophysicist (Santi Bosch) in a usually strictly wet lab (BCDN): how is it that extreme forces in amniotes primary neurulation do not break the highly dynamic neuroepithelium apart?
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Mechanical conditions preventing live cell extrusion during primary neurulation in amniotes https://www.biorxiv.org/content/10.1101/2025.08.08.668972v1
August 12, 2025 at 6:30 PM
Mechanical conditions preventing live cell extrusion during primary neurulation in amniotes https://www.biorxiv.org/content/10.1101/2025.08.08.668972v1
Mechanical conditions preventing live cell extrusion during primary neurulation in amniotes https://www.biorxiv.org/content/10.1101/2025.08.08.668972v1
August 12, 2025 at 6:30 PM
Mechanical conditions preventing live cell extrusion during primary neurulation in amniotes https://www.biorxiv.org/content/10.1101/2025.08.08.668972v1
29. The vert brain&spinal cord begin as an indentation in the top layer (ectoderm) of the embryo. It sinks in&folds on itself ~like pita bread folding to form a tube (process=neurulation). This tube will puff out in pairs of bulbs (vesicles). Each of these will eventually become yr brain bits
July 26, 2025 at 1:54 AM
29. The vert brain&spinal cord begin as an indentation in the top layer (ectoderm) of the embryo. It sinks in&folds on itself ~like pita bread folding to form a tube (process=neurulation). This tube will puff out in pairs of bulbs (vesicles). Each of these will eventually become yr brain bits
July 16, 2025 at 6:51 PM
Als Neurulation bezeichnet man die Bildung eines Neuralrohrs bei Chordatieren und damit auch beim Menschen. Das Neuralrohr ist die embryonale Anlage des späteren Zentralnervensystems ...
de.m.wikipedia.org/wiki/Neurula...
de.m.wikipedia.org/wiki/Neurula...
Neurulation – Wikipedia
de.m.wikipedia.org
July 16, 2025 at 6:48 PM
Als Neurulation bezeichnet man die Bildung eines Neuralrohrs bei Chordatieren und damit auch beim Menschen. Das Neuralrohr ist die embryonale Anlage des späteren Zentralnervensystems ...
de.m.wikipedia.org/wiki/Neurula...
de.m.wikipedia.org/wiki/Neurula...
Von der befruchteten Eizelle (Zygote) kommt es über Furchung, Blastulation, Gastrulation und Neurulation zur Bildung der Organanlagen (der Organogenese) führt.
de.m.wikipedia.org/wiki/Embryog...
de.m.wikipedia.org/wiki/Embryog...
Embryogenese (Mensch) – Wikipedia
de.m.wikipedia.org
July 16, 2025 at 6:47 PM
Von der befruchteten Eizelle (Zygote) kommt es über Furchung, Blastulation, Gastrulation und Neurulation zur Bildung der Organanlagen (der Organogenese) führt.
de.m.wikipedia.org/wiki/Embryog...
de.m.wikipedia.org/wiki/Embryog...
Hm, if I were going to attempt this I'd try placing an isolated neuron against the ventral surface of an early bean stage embryo and see if it will a) adhere and b) get internalized during neurulation / hypodermal enclosure
June 27, 2025 at 8:58 PM
Hm, if I were going to attempt this I'd try placing an isolated neuron against the ventral surface of an early bean stage embryo and see if it will a) adhere and b) get internalized during neurulation / hypodermal enclosure
Excited to share I’m starting my group in Dublin this September, supported by a Research Ireland Pathway award. We will work on neurulation mechanics using chicken embryos and human iPSCs. Looking forward to this new adventure! #newPI #womeninSTEM
Minister for Further and Higher Education, Research, Innovation and Science, James Lawless, has today announced €23 million in funding to support early-career researchers through the Research Ireland Pathway Programme. Read more: www.researchireland.ie/news/pathways/ #ResearchIreland
June 26, 2025 at 7:56 AM
Excited to share I’m starting my group in Dublin this September, supported by a Research Ireland Pathway award. We will work on neurulation mechanics using chicken embryos and human iPSCs. Looking forward to this new adventure! #newPI #womeninSTEM
Theoretical work in cell/molecular neuro!
Theoretical work in prenatal neurodevelopment (cell fatemapping, neurulation, mechanical morphogenesis, axon pathfinding, development of basal ganglia, hippocampus, cerebellum, thalamus, order of development, protomap theory, more)
And theories for glia!
Theoretical work in prenatal neurodevelopment (cell fatemapping, neurulation, mechanical morphogenesis, axon pathfinding, development of basal ganglia, hippocampus, cerebellum, thalamus, order of development, protomap theory, more)
And theories for glia!
We want to hear from you! We’re conducting a survey on the state of neuroscience. This week’s question is: What should neuroscience prioritize in the next 10 years?
#neuroskyence
thetransmitter.typeform.com/priorities?u...
#neuroskyence
thetransmitter.typeform.com/priorities?u...
What should neuroscience prioritize in the next 10 years?
We want to hear from you.
thetransmitter.typeform.com
May 16, 2025 at 1:07 PM
Theoretical work in cell/molecular neuro!
Theoretical work in prenatal neurodevelopment (cell fatemapping, neurulation, mechanical morphogenesis, axon pathfinding, development of basal ganglia, hippocampus, cerebellum, thalamus, order of development, protomap theory, more)
And theories for glia!
Theoretical work in prenatal neurodevelopment (cell fatemapping, neurulation, mechanical morphogenesis, axon pathfinding, development of basal ganglia, hippocampus, cerebellum, thalamus, order of development, protomap theory, more)
And theories for glia!
An alpine newt's journey starts with a single cell and progresses through complex stages of development. This National Geographic video captures cleavage, gastrulation, and neurulation in sharp detail. 🧬🌱
👉 Learn more: thekidshouldseethis.com/post...
#Biology
👉 Learn more: thekidshouldseethis.com/post...
#Biology
From zygote to hatched larva, a cell division time lapse
Cell division of an alpine newt. "In the film, we can observe a universal process which normally is invisible: the very beginning of an animal’s life."
thekidshouldseethis.com
April 14, 2025 at 3:01 PM
An alpine newt's journey starts with a single cell and progresses through complex stages of development. This National Geographic video captures cleavage, gastrulation, and neurulation in sharp detail. 🧬🌱
👉 Learn more: thekidshouldseethis.com/post...
#Biology
👉 Learn more: thekidshouldseethis.com/post...
#Biology
Embryonic development
Week 1. Implantation
Week 3. Gastrulation (3 layers: ectoderm, mesoderm, endoderm)
Week 4. Neurulation
Week 5. Neural crest cells migrate to distant sites
Week 1. Implantation
Week 3. Gastrulation (3 layers: ectoderm, mesoderm, endoderm)
Week 4. Neurulation
Week 5. Neural crest cells migrate to distant sites
March 30, 2025 at 8:37 PM
Embryonic development
Week 1. Implantation
Week 3. Gastrulation (3 layers: ectoderm, mesoderm, endoderm)
Week 4. Neurulation
Week 5. Neural crest cells migrate to distant sites
Week 1. Implantation
Week 3. Gastrulation (3 layers: ectoderm, mesoderm, endoderm)
Week 4. Neurulation
Week 5. Neural crest cells migrate to distant sites
The importance of forces was already known by mid 1800s (Entwicklungsmechanik–Roux), and by mid 1900s, magnetic dumb-bells placed on axolotl neural folds measured the force of neurulation = 0.1 µN.
Such setups elucidated the force-morphogenesis link
Such setups elucidated the force-morphogenesis link
March 23, 2025 at 2:14 AM
The importance of forces was already known by mid 1800s (Entwicklungsmechanik–Roux), and by mid 1900s, magnetic dumb-bells placed on axolotl neural folds measured the force of neurulation = 0.1 µN.
Such setups elucidated the force-morphogenesis link
Such setups elucidated the force-morphogenesis link
Defects in PRIMARY NEURULATION result in open neural tube defects, such as:
-Myelomeningocele (spinal cord & meninges protrude through vertebral arch defect).
ONTDs include:
↑maternal 𝛂-fetoprotein
-Myelomeningocele (spinal cord & meninges protrude through vertebral arch defect).
ONTDs include:
↑maternal 𝛂-fetoprotein
March 20, 2025 at 9:37 PM
Defects in PRIMARY NEURULATION result in open neural tube defects, such as:
-Myelomeningocele (spinal cord & meninges protrude through vertebral arch defect).
ONTDs include:
↑maternal 𝛂-fetoprotein
-Myelomeningocele (spinal cord & meninges protrude through vertebral arch defect).
ONTDs include:
↑maternal 𝛂-fetoprotein
Congratulations to Alastair Matheson-Grant who submitted his MSc in Genetics entitled “The genetic basis of secondary neurulation in Xenopus” yesterday!
March 18, 2025 at 12:13 AM
Congratulations to Alastair Matheson-Grant who submitted his MSc in Genetics entitled “The genetic basis of secondary neurulation in Xenopus” yesterday!
ORGANOGESIS occurs 3-8 weeks after fertilization, susceptible to teratogens.
NEURULATION (neural tube formation) occurs during weeks 3 & 4, during this process result in neural tube defects.
NEURULATION (neural tube formation) occurs during weeks 3 & 4, during this process result in neural tube defects.
February 25, 2025 at 11:05 PM
ORGANOGESIS occurs 3-8 weeks after fertilization, susceptible to teratogens.
NEURULATION (neural tube formation) occurs during weeks 3 & 4, during this process result in neural tube defects.
NEURULATION (neural tube formation) occurs during weeks 3 & 4, during this process result in neural tube defects.
Prickle2 regulates apical junction remodeling and tissue fluidity during vertebrate neurulation, say Miho Matsuda and Sergei Sokol: https://buff.ly/4hX8aVo
#Polarity #Development #CellSignaling
#Polarity #Development #CellSignaling
February 21, 2025 at 3:45 PM
Prickle2 regulates apical junction remodeling and tissue fluidity during vertebrate neurulation, say Miho Matsuda and Sergei Sokol: https://buff.ly/4hX8aVo
#Polarity #Development #CellSignaling
#Polarity #Development #CellSignaling
Meaning of #anencefalea anencefalea = anencefaliaLa anencephaly is a defect in the fusion of several sites of closure of the neural tube ( 2 for the merocraneo and the 2 and 4 for the 41 holocraneo; in the process of neurulation during embryogenesis. It occurs wh.. anencefalea
January 28, 2025 at 11:57 AM
Meaning of #anencefalea anencefalea = anencefaliaLa anencephaly is a defect in the fusion of several sites of closure of the neural tube ( 2 for the merocraneo and the 2 and 4 for the 41 holocraneo; in the process of neurulation during embryogenesis. It occurs wh.. anencefalea
Our work shows the conservation of an anterior co-expression module across deuterostomes. With the evolution of dorsal neurulation in the chordate ancestor, the anterior neural plate came under the influence of this gene module, leading to the development of the sensory-neurosecretory forebrain.
January 27, 2025 at 5:22 PM
Our work shows the conservation of an anterior co-expression module across deuterostomes. With the evolution of dorsal neurulation in the chordate ancestor, the anterior neural plate came under the influence of this gene module, leading to the development of the sensory-neurosecretory forebrain.
Investigation of aGRN genes in amphioxus revealed that early phase genes are co-expressed on the animal side and restrict anteriorly, while late phase genes appear in the anterior brain during neurulation, with a similar dynamic to apical organ development in echinoderms.
January 27, 2025 at 5:22 PM
Investigation of aGRN genes in amphioxus revealed that early phase genes are co-expressed on the animal side and restrict anteriorly, while late phase genes appear in the anterior brain during neurulation, with a similar dynamic to apical organ development in echinoderms.
