Our Virtual Clinical Case Conference in the Immunocompromised Child series returns today at 1:00 p.m. ET. Contact us to register for 'Pulmonary NTM (Mycobacterium abcessus) in a Heart Transplant Recipient with Non-CF Bronchiectasis.'
November 11, 2025 at 3:44 PM
Our Virtual Clinical Case Conference in the Immunocompromised Child series returns today at 1:00 p.m. ET. Contact us to register for 'Pulmonary NTM (Mycobacterium abcessus) in a Heart Transplant Recipient with Non-CF Bronchiectasis.'
Blood-based immunological signatures for extrapulmonary tuberculosis decoded
Tuberculosis is one of the world's leading infectious diseases. Infection with the bacterium Mycobacterium tuberculosis primarily affects the lungs, but in up to 25 per...
weiterlesen
Tuberculosis is one of the world's leading infectious diseases. Infection with the bacterium Mycobacterium tuberculosis primarily affects the lungs, but in up to 25 per...
weiterlesen
November 11, 2025 at 12:02 PM
Blood-based immunological signatures for extrapulmonary tuberculosis decoded
Tuberculosis is one of the world's leading infectious diseases. Infection with the bacterium Mycobacterium tuberculosis primarily affects the lungs, but in up to 25 per...
weiterlesen
Tuberculosis is one of the world's leading infectious diseases. Infection with the bacterium Mycobacterium tuberculosis primarily affects the lungs, but in up to 25 per...
weiterlesen
Blut-basierte immunologische Signaturen für extrapulmonale Tuberkulose entschlüsselt
Tuberkulose ist eine der weltweit führenden Infektionskrankheiten. Die Infektion mit dem Bakterium Mycobacterium tuberculosis befällt in erster Linie die Lu...
weiterlesen
Tuberkulose ist eine der weltweit führenden Infektionskrankheiten. Die Infektion mit dem Bakterium Mycobacterium tuberculosis befällt in erster Linie die Lu...
weiterlesen
November 11, 2025 at 12:00 PM
Blut-basierte immunologische Signaturen für extrapulmonale Tuberkulose entschlüsselt
Tuberkulose ist eine der weltweit führenden Infektionskrankheiten. Die Infektion mit dem Bakterium Mycobacterium tuberculosis befällt in erster Linie die Lu...
weiterlesen
Tuberkulose ist eine der weltweit führenden Infektionskrankheiten. Die Infektion mit dem Bakterium Mycobacterium tuberculosis befällt in erster Linie die Lu...
weiterlesen
In this Resources & Methods paper, Victoria Ektnitphong, @michaelshiloh.bsky.social & co developed a humanized lung-on-a-chip model that revealed early immune responses to a non-tuberculous #mycobacterium relevant for drug discovery
journals.biologists.com/dmm/article/...
journals.biologists.com/dmm/article/...
November 11, 2025 at 11:30 AM
In this Resources & Methods paper, Victoria Ektnitphong, @michaelshiloh.bsky.social & co developed a humanized lung-on-a-chip model that revealed early immune responses to a non-tuberculous #mycobacterium relevant for drug discovery
journals.biologists.com/dmm/article/...
journals.biologists.com/dmm/article/...
The study presents an LSTM-based #deeplearning framework combining classification and generative modeling to identify peptides active against Mycobacterium tuberculosis.
November 11, 2025 at 10:01 AM
The study presents an LSTM-based #deeplearning framework combining classification and generative modeling to identify peptides active against Mycobacterium tuberculosis.
🧬 Now published in Bioinformatics Advances: “LSTM-based deep learning model for the discovery of antimicrobial peptides targeting Mycobacterium tuberculosis.”
Read the full paper here: https://doi.org/10.1093/bioadv/vbaf274
Authors include: @taanec.bsky.social
Read the full paper here: https://doi.org/10.1093/bioadv/vbaf274
Authors include: @taanec.bsky.social
November 11, 2025 at 10:01 AM
🧬 Now published in Bioinformatics Advances: “LSTM-based deep learning model for the discovery of antimicrobial peptides targeting Mycobacterium tuberculosis.”
Read the full paper here: https://doi.org/10.1093/bioadv/vbaf274
Authors include: @taanec.bsky.social
Read the full paper here: https://doi.org/10.1093/bioadv/vbaf274
Authors include: @taanec.bsky.social
New immune response patterns for #tuberculosis discovered ...
| #TB | #bacteria | #Mycobacterium | #ImmuneSystem | #Lungs | Via uni-bonn .de
| #TB | #bacteria | #Mycobacterium | #ImmuneSystem | #Lungs | Via uni-bonn .de
New Immune Response Patterns for Tuberculosis Discovered Outside the Lungs
Researchers from the LIMES Institute at the University of Bonn, the German Center for Infection Research (DZIF), the German Center for Neurodegenerative Diseases (DZNE) and the University Hospital…
www.uni-bonn.de
November 11, 2025 at 6:00 AM
New immune response patterns for #tuberculosis discovered ...
| #TB | #bacteria | #Mycobacterium | #ImmuneSystem | #Lungs | Via uni-bonn .de
| #TB | #bacteria | #Mycobacterium | #ImmuneSystem | #Lungs | Via uni-bonn .de
This study used immunoinformatics and reverse vaccinology to evaluate the potential of Mycobacterium tuberculosis proteins MPT83 and MPT51 for vaccine development.
November 11, 2025 at 3:27 AM
This study used immunoinformatics and reverse vaccinology to evaluate the potential of Mycobacterium tuberculosis proteins MPT83 and MPT51 for vaccine development.
Future Research Directions on Mycobacterium tuberculosis Proteins pubmed.ncbi.nlm.nih.gov/41207945/ #cryoem
November 10, 2025 at 7:41 PM
Future Research Directions on Mycobacterium tuberculosis Proteins pubmed.ncbi.nlm.nih.gov/41207945/ #cryoem
MmpL12 transports lipooligosaccharides and impacts virulence in Mycobacterium marinum. Published Open Access and fee-free in Microbiology using a Publish and Read agreement: doi.org/10.1099/mic.... #MicrobioJ #PublishAndRead
November 10, 2025 at 4:30 PM
MmpL12 transports lipooligosaccharides and impacts virulence in Mycobacterium marinum. Published Open Access and fee-free in Microbiology using a Publish and Read agreement: doi.org/10.1099/mic.... #MicrobioJ #PublishAndRead
Mycobacteria are difficult, slow organisms. They hide everywhere and don't grow easily in the lab.
They also mimic other diseases, so before you realise you're dealing with TB...
The video seems...simplistic.
(Fun fact: a mycobacterium is responsible for leprosy too)
2/2
They also mimic other diseases, so before you realise you're dealing with TB...
The video seems...simplistic.
(Fun fact: a mycobacterium is responsible for leprosy too)
2/2
November 10, 2025 at 4:14 PM
Mycobacteria are difficult, slow organisms. They hide everywhere and don't grow easily in the lab.
They also mimic other diseases, so before you realise you're dealing with TB...
The video seems...simplistic.
(Fun fact: a mycobacterium is responsible for leprosy too)
2/2
They also mimic other diseases, so before you realise you're dealing with TB...
The video seems...simplistic.
(Fun fact: a mycobacterium is responsible for leprosy too)
2/2
▶️ Tuberkulose (1882): Koch entdeckte den Tuberkelbazillus (Mycobacterium tuberculosis) – eine bahnbrechende Leistung, da Tuberkulose die damalige Volksseuche Nummer eins war. Für diese Leistung erhielt er 1905 den Nobelpreis für Medizin.
10/19
10/19
November 10, 2025 at 8:48 AM
▶️ Tuberkulose (1882): Koch entdeckte den Tuberkelbazillus (Mycobacterium tuberculosis) – eine bahnbrechende Leistung, da Tuberkulose die damalige Volksseuche Nummer eins war. Für diese Leistung erhielt er 1905 den Nobelpreis für Medizin.
10/19
10/19
This study explored repurposing FDA-approved drugs to combat Mycobacterium abscessus, a dangerous non-tuberculous mycobacterial pathogen.
November 10, 2025 at 12:19 AM
This study explored repurposing FDA-approved drugs to combat Mycobacterium abscessus, a dangerous non-tuberculous mycobacterial pathogen.
#USfoodrecalls #USfoodsafety
⚠️ Consumption of raw, unpasteurized milk + milk products, can expose you to:
*A(H5N1) Avian flu
*Campylobacter
*Cryptosporidium
*E. Coli
*Listeria
*Brucella (Brucellosis)
*Salmonella
*Mycobacterium bovis (Bovine Tuberculosis)
www.cdc.gov/food-safety/...
⚠️ Consumption of raw, unpasteurized milk + milk products, can expose you to:
*A(H5N1) Avian flu
*Campylobacter
*Cryptosporidium
*E. Coli
*Listeria
*Brucella (Brucellosis)
*Salmonella
*Mycobacterium bovis (Bovine Tuberculosis)
www.cdc.gov/food-safety/...
Raw Milk
Consuming raw milk and raw milk products can pose health risks.
www.cdc.gov
November 9, 2025 at 2:46 AM
#USfoodrecalls #USfoodsafety
⚠️ Consumption of raw, unpasteurized milk + milk products, can expose you to:
*A(H5N1) Avian flu
*Campylobacter
*Cryptosporidium
*E. Coli
*Listeria
*Brucella (Brucellosis)
*Salmonella
*Mycobacterium bovis (Bovine Tuberculosis)
www.cdc.gov/food-safety/...
⚠️ Consumption of raw, unpasteurized milk + milk products, can expose you to:
*A(H5N1) Avian flu
*Campylobacter
*Cryptosporidium
*E. Coli
*Listeria
*Brucella (Brucellosis)
*Salmonella
*Mycobacterium bovis (Bovine Tuberculosis)
www.cdc.gov/food-safety/...
Defining the Mycobacterium tuberculosis Pangenome and Suggestions for a New Composite Reference Sequence. #MycobacteriumTuberculosis #Pangenome #ReferenceSequence @biorxivpreprint.bsky.social 🧪
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
November 8, 2025 at 11:49 AM
Defining the Mycobacterium tuberculosis Pangenome and Suggestions for a New Composite Reference Sequence. #MycobacteriumTuberculosis #Pangenome #ReferenceSequence @biorxivpreprint.bsky.social 🧪
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
A functional amyloid matrix underpins the PDIM-architected corded superstructure of the Mycobacterium tuberculosis biofilm https://www.biorxiv.org/content/10.1101/2025.11.07.687260v1
November 8, 2025 at 4:19 AM
A functional amyloid matrix underpins the PDIM-architected corded superstructure of the Mycobacterium tuberculosis biofilm https://www.biorxiv.org/content/10.1101/2025.11.07.687260v1
A functional amyloid matrix underpins the PDIM-architected corded superstructure of the Mycobacterium tuberculosis biofilm https://www.biorxiv.org/content/10.1101/2025.11.07.687260v1
November 8, 2025 at 4:19 AM
A functional amyloid matrix underpins the PDIM-architected corded superstructure of the Mycobacterium tuberculosis biofilm https://www.biorxiv.org/content/10.1101/2025.11.07.687260v1
In today’s #GrandRounds, David B. Clifford, MD, shared his decades-long journey in infectious disease research and clinical care including solving the mystery of infectious myelitis caused by the rare Mycobacterium haemophilum in patients with a GATA2 gene mutation.
November 7, 2025 at 7:53 PM
In today’s #GrandRounds, David B. Clifford, MD, shared his decades-long journey in infectious disease research and clinical care including solving the mystery of infectious myelitis caused by the rare Mycobacterium haemophilum in patients with a GATA2 gene mutation.
#NewResearch
Prodrug florfenicol amine is activated by intrinsic resistance to target Mycobacterium abscessus
#microsky #IDsky
www.nature.com/articles/s41...
Prodrug florfenicol amine is activated by intrinsic resistance to target Mycobacterium abscessus
#microsky #IDsky
www.nature.com/articles/s41...
Prodrug florfenicol amine is activated by intrinsic resistance to target Mycobacterium abscessus - Nature Microbiology
Florfenicol amine hijacks intrinsic resistance in Mycobacterium abscessus, highlighting that antimicrobial resistance mechanisms can be harnessed for antibiotic activation.
www.nature.com
November 7, 2025 at 11:11 AM
#NewResearch
Prodrug florfenicol amine is activated by intrinsic resistance to target Mycobacterium abscessus
#microsky #IDsky
www.nature.com/articles/s41...
Prodrug florfenicol amine is activated by intrinsic resistance to target Mycobacterium abscessus
#microsky #IDsky
www.nature.com/articles/s41...
Groundbreaking system enables in-depth studies of how tuberculosis spreads through the air, revealing key insights about Mycobacterium tuberculosis' adaptations during transmission betwee...
🧵 Thread below
Full analysis: https://helixbrief.com/article/a4ff8da8-9c91-405c-a028-9af22614477b
🧵 Thread below
Full analysis: https://helixbrief.com/article/a4ff8da8-9c91-405c-a028-9af22614477b
November 6, 2025 at 10:15 PM
Groundbreaking system enables in-depth studies of how tuberculosis spreads through the air, revealing key insights about Mycobacterium tuberculosis' adaptations during transmission betwee...
🧵 Thread below
Full analysis: https://helixbrief.com/article/a4ff8da8-9c91-405c-a028-9af22614477b
🧵 Thread below
Full analysis: https://helixbrief.com/article/a4ff8da8-9c91-405c-a028-9af22614477b
Mycobacterium tuberculosis transmission in China during the COVID-19 pandemic period (2020-2021) compared with the pre-pandemic period (2017-2019)
->Nature | More from Lil Dr Glen EcoChat at BigEarthData.ai
->Nature | More from Lil Dr Glen EcoChat at BigEarthData.ai
Mycobacterium tuberculosis transmission in China during the COVID-19 pandemic period (2020-2021) compared with the pre-pandemic period (2017-2019)
Using data from over 1.9 million adolescents who underwent tuberculin skin tests from 2017 to 2021 in eastern China, this study provides strong empirical evidence that M. tuberculosis transmission may have declined after the start of the COVID-19 pandemic in...
www.nature.com
November 6, 2025 at 8:30 PM
Retraction: Mycobacterium indicus pranii (Mw) Re-Establishes Host Protective Immune Response in Leishmania donovani Infected Macrophages: Critical Role of IL-12 pubmed.ncbi.nlm.nih.gov/41191580/
November 6, 2025 at 6:53 PM
Retraction: Mycobacterium indicus pranii (Mw) Re-Establishes Host Protective Immune Response in Leishmania donovani Infected Macrophages: Critical Role of IL-12 pubmed.ncbi.nlm.nih.gov/41191580/
Population structure of Mycobacterium avium subsp. hominissuis provides new insights into genomic evolution https://pubmed.ncbi.nlm.nih.gov/41186983/
November 6, 2025 at 9:50 AM
Population structure of Mycobacterium avium subsp. hominissuis provides new insights into genomic evolution https://pubmed.ncbi.nlm.nih.gov/41186983/
Immunopeptidomics can inform the design of mRNA vaccines for the delivery of Mycobacterium tuberculosis MHC class II antigens https://pubmed.ncbi.nlm.nih.gov/41191777/
November 6, 2025 at 5:39 AM
Immunopeptidomics can inform the design of mRNA vaccines for the delivery of Mycobacterium tuberculosis MHC class II antigens https://pubmed.ncbi.nlm.nih.gov/41191777/
In vitro pharmacokinetics and pharmacodynamics of the diarylquinoline TBAJ-587 and its metabolites against Mycobacterium tuberculosis https://www.biorxiv.org/content/10.1101/2025.11.05.686716v1
November 6, 2025 at 4:02 AM
In vitro pharmacokinetics and pharmacodynamics of the diarylquinoline TBAJ-587 and its metabolites against Mycobacterium tuberculosis https://www.biorxiv.org/content/10.1101/2025.11.05.686716v1