#helixer
Catching up with the Helixer Team @usadellab — over 1,000 plant genomes annotated and counting! 🌱📊
September 24, 2025 at 2:00 PM
Inspired by Helixer (by @AlisandraDenton ), we explore the potential of deep learning for genome annotation. We introduce Tiberius for highly accurate ab initio prediction of protein coding genes in mammals. Tiberius beats Augustus, BRAKER3, and Galba. doi.org/10.1101/2024...
Tiberius: End-to-End Deep Learning with an HMM for Gene Prediction
bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
doi.org
July 24, 2024 at 5:28 AM
Helixer and Tiberius have made it super easy for non-model species now. No RNA/protein sequence data required, you just feed a genome assembly to the program and it finds the genes
August 26, 2025 at 7:51 AM
Åh sånn har jeg åå lyst på! sånne helixer er så fint 😍
March 6, 2024 at 2:24 PM
..and finally Marie's new Helixer models for Solanales at #SOLRUB2025
September 23, 2025 at 9:04 AM
14/ And finally, a teaser: We're gearing up to release deep-learning-based Helixer annotations and NLR sequences for 230 superasterid genomes on @datadryad & @ZENODO_ORG! Stay tuned.
February 26, 2025 at 4:55 PM
really liked the lighting on this one :) artfight attack for Helixer
August 26, 2023 at 9:03 PM
Commission for helixer and kasierrelkin
Art by Me
#SpicyDS #Commission #Art #Furry #penis #frotting #condom #snugglies #bursting
August 24, 2025 at 7:30 PM
nice resource. You can check out helixer for setp 10 www.plabipd.de/helixer_main... so you don't need to train for plants for up to ca 1GB online above this useGalaxy or download it.
Helixer structural gene annotation
www.plabipd.de
August 22, 2025 at 8:09 AM
Has anyone ever had helixer find way too many genes in a genome? I'm working on some Solanum assemblies (all same species). For only one of them, helixer is finding ~20k genes too many. For the life of me, I can't figure out why.
September 24, 2025 at 12:20 PM
Happy to share that our Helixer deeplearning-based annotation of 230 superasterid genomes is now online on
@datadryad.bsky.social
💻🌱

doi.org/10.5061/drya...

Check out how we used 69 of them to study the molecular evolution of a plant immune receptor network here! 👇
May 9, 2025 at 11:19 AM
YCH for ~helixer
April 21, 2025 at 10:52 AM
4/ We reannotated 40 Solanales + 29 Asterales genomes with the AI tool Helixer (see post #14). These lineages diverged ~100 MYA! Unlike Solanales (~50% of all NLRs), the NRC network shows much less expansion in Asterales (~6%).
February 26, 2025 at 4:55 PM
Curious to see what happen if all genome were re-annotated by helixer only.
August 18, 2025 at 5:50 PM
Commission for helixer and kasierrelkin
Art by Me
#SpicyDS #Commission #Art #Furry #penis #frotting #condom #snugglies
August 23, 2025 at 7:30 PM
Marie explains how she selects data for her Helixer gene annotations using Mercator quality control and Pubplant for genome selection at #SOLRUB2025.
Read more about Pubplant:
www.frontiersin.org/journals/pla...
September 23, 2025 at 8:59 AM
Tiberius was inspired by Helixer. Helixer is a deep neural network that uses CNN & LSTM layers & an HMM to perform gene prediction. Great work by team of Alisandra Denton.
November 20, 2024 at 3:57 PM
Sketch for Helixer
February 4, 2025 at 12:47 AM
Marie Bolger closes the session at the #SOLRUB2025 with a presentation about the application of Helixer to the annotation of the #Solanaceae genomes.
September 23, 2025 at 8:51 AM
1. Zarizav
2. Törring (Helixer)
3. Bai (Laobai)
4. Gauss
June 15, 2025 at 5:10 AM
🚀 New Helixer tutorial for gene prediction! Predict genes in complex genomes like maize with 1 command—no repeatmasking, no extra data needed, all under 4 hrs! 🌽💻
Check it out: rcac-bioinformatics.readthedocs.io/en/latest/he...
#Bioinformatics #Genomics #RCAC
Gene prediction using Helixer — RCAC bioinformatics tutorials
rcac-bioinformatics.readthedocs.io
October 31, 2024 at 2:42 PM