#genetic_algorithm
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In this work, we used a genetic algorithm to design PMB2-like macrocycles with similar antimicrobial activity and lower toxicity, offering a general strategy to explore macrocyclic natural products.
#genetic_algorithm #antimicrobial
Antimicrobial Peptide‐Peptoid Macrocycles from the Polymyxin B2 Chemical Space
We optimized mixed peptide-peptoid sequences for molecular similarity to the macrocyclic lipopeptide antibiotic polymyxin B2 (PMB2) using a genetic algorithm. Synthesis and testing of top-scoring com...
onlinelibrary.wiley.com
April 4, 2025 at 9:11 AM
Vertical and horizontal lines only. 1000 overlapping lines made with genetic algorithm Is painting recognizable?

#genuary #genuary1 #genclub #genart #genetic_algorithm
January 2, 2025 at 10:16 AM
Genetic algorithm - Wikipedia
en.m.wikipedia.org
November 3, 2024 at 7:41 PM