They infect mammals worldwide—but, so far, not humans. 🧬
Join Dr. Adam Bailey on Nov. 18 at 10 a.m. ET for a free webinar on new insights into arterivirus receptor usage and host interactions. asm.social/2Fj
#Virology #ViralEvolution #Research #JVI #Arterivirus
Join Dr. Adam Bailey on Nov. 18 at 10 a.m. ET for a free webinar on new insights into arterivirus receptor usage and host interactions. asm.social/2Fj
#Virology #ViralEvolution #Research #JVI #Arterivirus
October 29, 2025 at 4:27 PM
They infect mammals worldwide—but, so far, not humans. 🧬
Join Dr. Adam Bailey on Nov. 18 at 10 a.m. ET for a free webinar on new insights into arterivirus receptor usage and host interactions. asm.social/2Fj
#Virology #ViralEvolution #Research #JVI #Arterivirus
Join Dr. Adam Bailey on Nov. 18 at 10 a.m. ET for a free webinar on new insights into arterivirus receptor usage and host interactions. asm.social/2Fj
#Virology #ViralEvolution #Research #JVI #Arterivirus
A Man Had COVID For 750 Days Straight and His Body Became an Incubator For Virus Evolution #Science #HealthandMedicine #InfectiousDiseases #COVID19 #ViralEvolution
A Man Had COVID For 750 Days Straight and His Body Became an Incubator For Virus Evolution
Learn more about the longest documented case of COVID-19 found in an American man living with HIV.
purescience.news
September 18, 2025 at 7:00 AM
A Man Had COVID For 750 Days Straight and His Body Became an Incubator For Virus Evolution #Science #HealthandMedicine #InfectiousDiseases #COVID19 #ViralEvolution
#Virology #ViralEvolution
September 5, 2025 at 8:52 PM
#Virology #ViralEvolution
8/14 Evolution continues: As H5N1 spreads among cows, cats, and other animals, virus mutation risk increases.
"The probability of mutation or reassortment events that could support human-to-human transmission" grows with each infection, experts warn.
#ViralEvolution
"The probability of mutation or reassortment events that could support human-to-human transmission" grows with each infection, experts warn.
#ViralEvolution
August 28, 2025 at 4:12 PM
8/14 Evolution continues: As H5N1 spreads among cows, cats, and other animals, virus mutation risk increases.
"The probability of mutation or reassortment events that could support human-to-human transmission" grows with each infection, experts warn.
#ViralEvolution
"The probability of mutation or reassortment events that could support human-to-human transmission" grows with each infection, experts warn.
#ViralEvolution
🦠 New research reveals that 8% of the human genome is composed of ancient viral fragments, highlighting the deep evolutionary connection between humans and viruses. Link: https://tinyurl.com/23mgvqqb #Genomics #ViralEvolution #HumanBiology
August 27, 2025 at 9:00 PM
🦠 New research reveals that 8% of the human genome is composed of ancient viral fragments, highlighting the deep evolutionary connection between humans and viruses. Link: https://tinyurl.com/23mgvqqb #Genomics #ViralEvolution #HumanBiology
Viral adaptation is a major theme: a universal antiviral could rapidly drive viruses to evolve resistance, mirroring the challenge of antibiotic resistance in bacteria. Viruses are incredibly resilient. #ViralEvolution 4/6
August 27, 2025 at 7:00 PM
Viral adaptation is a major theme: a universal antiviral could rapidly drive viruses to evolve resistance, mirroring the challenge of antibiotic resistance in bacteria. Viruses are incredibly resilient. #ViralEvolution 4/6
8/12 The research reveals viral evolution trade-offs:
Rigid protein conformations = higher infectivity but allow immunity to work faster
Flexible conformations = immune escape but potentially lower binding efficiency
#ViralEvolution
Rigid protein conformations = higher infectivity but allow immunity to work faster
Flexible conformations = immune escape but potentially lower binding efficiency
#ViralEvolution
August 26, 2025 at 2:56 PM
8/12 The research reveals viral evolution trade-offs:
Rigid protein conformations = higher infectivity but allow immunity to work faster
Flexible conformations = immune escape but potentially lower binding efficiency
#ViralEvolution
Rigid protein conformations = higher infectivity but allow immunity to work faster
Flexible conformations = immune escape but potentially lower binding efficiency
#ViralEvolution
8/11 Scientists found one intriguing detail: H5N1's neuraminidase protein shares 89.6% amino acid identity with seasonal H1N1, suggesting possible partial protection through conserved epitopes.
But antibody tests detected none.
#ViralEvolution
But antibody tests detected none.
#ViralEvolution
August 22, 2025 at 9:42 PM
8/11 Scientists found one intriguing detail: H5N1's neuraminidase protein shares 89.6% amino acid identity with seasonal H1N1, suggesting possible partial protection through conserved epitopes.
But antibody tests detected none.
#ViralEvolution
But antibody tests detected none.
#ViralEvolution
Comparative benchmarking of viral phylogeography methods reveals how different models reconstruct spatial spread under varied outbreak scenarios
#Phylogeography #ViralEvolution #BioinformaticsMethods
👤EVBC: Simon Dellicour, Philippe Lemey, Sebastian Lequime
🔗
#Phylogeography #ViralEvolution #BioinformaticsMethods
👤EVBC: Simon Dellicour, Philippe Lemey, Sebastian Lequime
🔗
Comparative performance of viral landscape phylogeography approaches | PNAS
The rapid evolution of RNA viruses implies that their evolutionary and ecological processes occur on the same time scale. Genome sequences of these...
doi.org
August 22, 2025 at 5:44 AM
Comparative benchmarking of viral phylogeography methods reveals how different models reconstruct spatial spread under varied outbreak scenarios
#Phylogeography #ViralEvolution #BioinformaticsMethods
👤EVBC: Simon Dellicour, Philippe Lemey, Sebastian Lequime
🔗
#Phylogeography #ViralEvolution #BioinformaticsMethods
👤EVBC: Simon Dellicour, Philippe Lemey, Sebastian Lequime
🔗
#H5N1 #H5Nx #AvianInfluenza #Reassortment #ViralEvolution #OneHealth #Panzootic
📚 References:
🔹 Baxter et al., 2025. doi.org/10.1101/2025...
🔹 Gong et al., 2025. doi.org/10.1371/jour...
12/12
📚 References:
🔹 Baxter et al., 2025. doi.org/10.1101/2025...
🔹 Gong et al., 2025. doi.org/10.1371/jour...
12/12
The Winners Take It All? Evolutionary Success of H5Nx Reassortants in the 2020–2024 Panzootic
Avian influenza viruses undergo frequent genetic reassortment, which can coincide with phenotypic changes in transmission, pathogenicity, and host species niche. Since 2020, clade 2.3.4.4b H5 high pat...
doi.org
August 4, 2025 at 2:31 PM
#H5N1 #H5Nx #AvianInfluenza #Reassortment #ViralEvolution #OneHealth #Panzootic
📚 References:
🔹 Baxter et al., 2025. doi.org/10.1101/2025...
🔹 Gong et al., 2025. doi.org/10.1371/jour...
12/12
📚 References:
🔹 Baxter et al., 2025. doi.org/10.1101/2025...
🔹 Gong et al., 2025. doi.org/10.1371/jour...
12/12
Wu Lab at Rowan University unveils a better method for studying adaptation: the c/µ test. It works on UTRs, accounts for synonymous mutations, and avoids false positives. Implications for viral evolution studies. go.njmicrobe.org/Up7l2R #Genomics #ViralEvolution #MolecularBiology
Unlocking Deeper Insights into Viral Evolution: Why the New c/µ Test Matters
For decades, evolutionary biologists have used the Ka/Ks ratio test to explore how genes adapt and change over time. This traditional test compares the rate of nonsynonymous (amino acid-changing) subs...
go.njmicrobe.org
July 25, 2025 at 2:44 PM
Wu Lab at Rowan University unveils a better method for studying adaptation: the c/µ test. It works on UTRs, accounts for synonymous mutations, and avoids false positives. Implications for viral evolution studies. go.njmicrobe.org/Up7l2R #Genomics #ViralEvolution #MolecularBiology
Super-pangenome analysis of 3562 human and animal papillomavirus isolates illuminates their genome and pathogenicity evolution
Chen, C., Chen, J. et al.
Paper
Details
#ViralEvolution #PapillomavirusResearch #SuperPangenomeStudy
Chen, C., Chen, J. et al.
Paper
Details
#ViralEvolution #PapillomavirusResearch #SuperPangenomeStudy
July 22, 2025 at 4:02 PM
Super-pangenome analysis of 3562 human and animal papillomavirus isolates illuminates their genome and pathogenicity evolution
Chen, C., Chen, J. et al.
Paper
Details
#ViralEvolution #PapillomavirusResearch #SuperPangenomeStudy
Chen, C., Chen, J. et al.
Paper
Details
#ViralEvolution #PapillomavirusResearch #SuperPangenomeStudy
#H5N1 #InfluenzaA #GenomicSurveillance #ViralEvolution #OneHealth #BirdMigration #Spillover #ScienceAdvances
📚 Signore et al., 2025
Science Advances, 11(28): eadu4909
🔗 doi.org/10.1126/scia...
(12/12)
📚 Signore et al., 2025
Science Advances, 11(28): eadu4909
🔗 doi.org/10.1126/scia...
(12/12)
Spatiotemporal reconstruction of the North American A(H5N1) outbreak reveals successive lineage replacements by descendant reassortants
Phylodynamics show the reassortant progeny of Eurasian H5 clade 2.3.4.4b and American LPAI viruses outcompeted their ancestors.
doi.org
July 14, 2025 at 4:24 PM
#H5N1 #InfluenzaA #GenomicSurveillance #ViralEvolution #OneHealth #BirdMigration #Spillover #ScienceAdvances
📚 Signore et al., 2025
Science Advances, 11(28): eadu4909
🔗 doi.org/10.1126/scia...
(12/12)
📚 Signore et al., 2025
Science Advances, 11(28): eadu4909
🔗 doi.org/10.1126/scia...
(12/12)
3/12 Researchers identified 62 unique H5N1 genotypes in Canada alone.
The virus extensively reassorted with local low-pathogenic influenza viruses, creating novel combinations that challenge traditional understanding of viral evolution.
#ViralEvolution #Reassortment
The virus extensively reassorted with local low-pathogenic influenza viruses, creating novel combinations that challenge traditional understanding of viral evolution.
#ViralEvolution #Reassortment
July 10, 2025 at 7:10 PM
3/12 Researchers identified 62 unique H5N1 genotypes in Canada alone.
The virus extensively reassorted with local low-pathogenic influenza viruses, creating novel combinations that challenge traditional understanding of viral evolution.
#ViralEvolution #Reassortment
The virus extensively reassorted with local low-pathogenic influenza viruses, creating novel combinations that challenge traditional understanding of viral evolution.
#ViralEvolution #Reassortment
9/10 Even with optimal preparation, experts expect surprises."
This H5 virus has taught us that these viruses are always one step ahead of us," warns researcher Sorrell.
The evolution continues, whether we're ready or not.
#ViralEvolution
This H5 virus has taught us that these viruses are always one step ahead of us," warns researcher Sorrell.
The evolution continues, whether we're ready or not.
#ViralEvolution
July 10, 2025 at 6:29 PM
9/10 Even with optimal preparation, experts expect surprises."
This H5 virus has taught us that these viruses are always one step ahead of us," warns researcher Sorrell.
The evolution continues, whether we're ready or not.
#ViralEvolution
This H5 virus has taught us that these viruses are always one step ahead of us," warns researcher Sorrell.
The evolution continues, whether we're ready or not.
#ViralEvolution
2/10 Virologist Anice Lowen from Emory University raises alarming concerns about vaccines that limit disease but don't prevent infection.
Such approaches could allow H5N1 to continue replicating and evolving while appearing controlled.
#Vaccines #ViralEvolution
Such approaches could allow H5N1 to continue replicating and evolving while appearing controlled.
#Vaccines #ViralEvolution
July 10, 2025 at 6:23 PM
2/10 Virologist Anice Lowen from Emory University raises alarming concerns about vaccines that limit disease but don't prevent infection.
Such approaches could allow H5N1 to continue replicating and evolving while appearing controlled.
#Vaccines #ViralEvolution
Such approaches could allow H5N1 to continue replicating and evolving while appearing controlled.
#Vaccines #ViralEvolution
2/12 Two new H5N1 genotypes emerged in the US:
• B3.13 (March 2024) - cattle-adapted strain
• D1.1 (January 2025) - more severe human illness
These "reassortant" viruses combine deadly bird flu genes with local influenza, creating unprecedented pandemic threats.
#ViralEvolution #Genotypes
• B3.13 (March 2024) - cattle-adapted strain
• D1.1 (January 2025) - more severe human illness
These "reassortant" viruses combine deadly bird flu genes with local influenza, creating unprecedented pandemic threats.
#ViralEvolution #Genotypes
July 6, 2025 at 3:44 PM
2/12 Two new H5N1 genotypes emerged in the US:
• B3.13 (March 2024) - cattle-adapted strain
• D1.1 (January 2025) - more severe human illness
These "reassortant" viruses combine deadly bird flu genes with local influenza, creating unprecedented pandemic threats.
#ViralEvolution #Genotypes
• B3.13 (March 2024) - cattle-adapted strain
• D1.1 (January 2025) - more severe human illness
These "reassortant" viruses combine deadly bird flu genes with local influenza, creating unprecedented pandemic threats.
#ViralEvolution #Genotypes
🦠 SARS-CoV-2's sneaky evolution decoded! Viral variants outsmart immune defenses through strategic gene shifts. 🧬 Genomic detective work reveals how COVID adapts & survives. 🔬 #ViralEvolution #Genomics #ScienceBreakthrough https://emmecola.github.io/genomics-daily
July 5, 2025 at 6:32 AM
🦠 SARS-CoV-2's sneaky evolution decoded! Viral variants outsmart immune defenses through strategic gene shifts. 🧬 Genomic detective work reveals how COVID adapts & survives. 🔬 #ViralEvolution #Genomics #ScienceBreakthrough https://emmecola.github.io/genomics-daily
The impact of clade B lineage 5 MERS coronaviruses spike mutations from 2015 to 2023 on virus entry and replication competence
Lau, K. K., Peiris, M. et al.
Paper
Details
#MERSvirus #SpikeMutations #ViralEvolution
Lau, K. K., Peiris, M. et al.
Paper
Details
#MERSvirus #SpikeMutations #ViralEvolution
July 2, 2025 at 9:01 AM
The impact of clade B lineage 5 MERS coronaviruses spike mutations from 2015 to 2023 on virus entry and replication competence
Lau, K. K., Peiris, M. et al.
Paper
Details
#MERSvirus #SpikeMutations #ViralEvolution
Lau, K. K., Peiris, M. et al.
Paper
Details
#MERSvirus #SpikeMutations #ViralEvolution
📣@inrae-france.bsky.social publie son rapport d'activité 2024. #agriculture #biodiversité #oneHealth #ClimateChange
🔗https://www.inrae.fr/actualites/rapport-dactivite-inrae-2024
👍Retrouvez les faits marquants de nos recherches en pages 31 et 40 de ce rapport : #ViralEvolution #DiseaseControl 👍
🔗https://www.inrae.fr/actualites/rapport-dactivite-inrae-2024
👍Retrouvez les faits marquants de nos recherches en pages 31 et 40 de ce rapport : #ViralEvolution #DiseaseControl 👍
June 30, 2025 at 8:09 AM
📣@inrae-france.bsky.social publie son rapport d'activité 2024. #agriculture #biodiversité #oneHealth #ClimateChange
🔗https://www.inrae.fr/actualites/rapport-dactivite-inrae-2024
👍Retrouvez les faits marquants de nos recherches en pages 31 et 40 de ce rapport : #ViralEvolution #DiseaseControl 👍
🔗https://www.inrae.fr/actualites/rapport-dactivite-inrae-2024
👍Retrouvez les faits marquants de nos recherches en pages 31 et 40 de ce rapport : #ViralEvolution #DiseaseControl 👍
2/5
Why care about BA.3.2?
Most variants differ from their ancestors by just a few spike mutations. BA.3.2, however, shows extensive spike divergence - likely from long-term infection of an immunocompromised patient.
#ViralEvolution
Why care about BA.3.2?
Most variants differ from their ancestors by just a few spike mutations. BA.3.2, however, shows extensive spike divergence - likely from long-term infection of an immunocompromised patient.
#ViralEvolution
June 30, 2025 at 8:00 AM
2/5
Why care about BA.3.2?
Most variants differ from their ancestors by just a few spike mutations. BA.3.2, however, shows extensive spike divergence - likely from long-term infection of an immunocompromised patient.
#ViralEvolution
Why care about BA.3.2?
Most variants differ from their ancestors by just a few spike mutations. BA.3.2, however, shows extensive spike divergence - likely from long-term infection of an immunocompromised patient.
#ViralEvolution
2/9 The 2023 grey seal H5N1 strain killed ferrets within 3 days.
In stark contrast, the older 2005 Indonesian strain allowed all test animals to survive until at least day 4.
This accelerated mortality represents a concerning evolution in viral pathogenicity.
#ViralEvolution
In stark contrast, the older 2005 Indonesian strain allowed all test animals to survive until at least day 4.
This accelerated mortality represents a concerning evolution in viral pathogenicity.
#ViralEvolution
June 29, 2025 at 6:05 PM
2/9 The 2023 grey seal H5N1 strain killed ferrets within 3 days.
In stark contrast, the older 2005 Indonesian strain allowed all test animals to survive until at least day 4.
This accelerated mortality represents a concerning evolution in viral pathogenicity.
#ViralEvolution
In stark contrast, the older 2005 Indonesian strain allowed all test animals to survive until at least day 4.
This accelerated mortality represents a concerning evolution in viral pathogenicity.
#ViralEvolution
8/9 THE MUTATION CONCERN:
As a researcher noted: "We'll never catch up with Mother Nature. We're never gonna catch up with the virus and how it mutates."
Goal is detecting mutations that make virus "more mammalian adaptable" before it's too late.
#MutationRace #ViralEvolution #MammalianAdaptation
As a researcher noted: "We'll never catch up with Mother Nature. We're never gonna catch up with the virus and how it mutates."
Goal is detecting mutations that make virus "more mammalian adaptable" before it's too late.
#MutationRace #ViralEvolution #MammalianAdaptation
June 23, 2025 at 10:44 PM
8/9 THE MUTATION CONCERN:
As a researcher noted: "We'll never catch up with Mother Nature. We're never gonna catch up with the virus and how it mutates."
Goal is detecting mutations that make virus "more mammalian adaptable" before it's too late.
#MutationRace #ViralEvolution #MammalianAdaptation
As a researcher noted: "We'll never catch up with Mother Nature. We're never gonna catch up with the virus and how it mutates."
Goal is detecting mutations that make virus "more mammalian adaptable" before it's too late.
#MutationRace #ViralEvolution #MammalianAdaptation
3/12 THE 1997 BREAKTHROUGH: Everything changed when a 3-year-old boy in Hong Kong died from H5N1.
"We didn't expect to see high-path avian influenza viruses infecting humans. We just didn't expect that."
Scientists thought bird and human flu were separate
#HongKong1997 #H5N1History #ViralEvolution
"We didn't expect to see high-path avian influenza viruses infecting humans. We just didn't expect that."
Scientists thought bird and human flu were separate
#HongKong1997 #H5N1History #ViralEvolution
June 23, 2025 at 10:20 PM
3/12 THE 1997 BREAKTHROUGH: Everything changed when a 3-year-old boy in Hong Kong died from H5N1.
"We didn't expect to see high-path avian influenza viruses infecting humans. We just didn't expect that."
Scientists thought bird and human flu were separate
#HongKong1997 #H5N1History #ViralEvolution
"We didn't expect to see high-path avian influenza viruses infecting humans. We just didn't expect that."
Scientists thought bird and human flu were separate
#HongKong1997 #H5N1History #ViralEvolution