Excited to share our newest manuscript on antigen discovery and vaccine design for tuberculosis lead by Owen Leddy (everyone hiring new faculty in a few years, remember this name!)
www.science.org/doi/10.1126/... #TBsky
www.science.org/doi/10.1126/... #TBsky
Immunopeptidomics can inform the design of mRNA vaccines for the delivery of Mycobacterium tuberculosis MHC class II antigens
MHC class II immunopeptidomics in human phagocytes infected with Mycobacterium tuberculosis enables vaccine immunogen design and optimization.
www.science.org
November 5, 2025 at 9:57 PM
Excited to share our newest manuscript on antigen discovery and vaccine design for tuberculosis lead by Owen Leddy (everyone hiring new faculty in a few years, remember this name!)
www.science.org/doi/10.1126/... #TBsky
www.science.org/doi/10.1126/... #TBsky
Not infectious ≠ not affected! Check out our latest TB Ed Talk with Dr. Carole Mitnick, where she shares the importance of patient centered care that continues post-TB. Plus a CTA that's right up our alley (spoiler: it involves memes)
www.youtube.com/watc...
#TBSky #MedSky #IDSky #PublicHealth
www.youtube.com/watc...
#TBSky #MedSky #IDSky #PublicHealth
TB Ed Talk: LIBRE-Post TB: A Pilot Intervention for Post-TB Lung Disease from Dr. Carole Mitnick
Dr. Carole Mitnick will introduce the phenomenon of post-TB lung disease (PTLD), which may affect up to 60% of people who are cured of TB. She will also discuss a pilot intervention for PTLD developed by Socios En Salud (PIH in Peru) to help people with respiratory symptoms after TB. And she will re
www.youtube.com
October 29, 2025 at 10:10 PM
Not infectious ≠ not affected! Check out our latest TB Ed Talk with Dr. Carole Mitnick, where she shares the importance of patient centered care that continues post-TB. Plus a CTA that's right up our alley (spoiler: it involves memes)
www.youtube.com/watc...
#TBSky #MedSky #IDSky #PublicHealth
www.youtube.com/watc...
#TBSky #MedSky #IDSky #PublicHealth
Ok, I've learned something new - acid fast stains bind nucleic acids and not mycolic acid on mycobacterial cell wall. The lipid-rich cell wall simply prevents acid-alcohol decolourisation, hence acid -fast.
#TBSky #IDSky @lancetmicrobe.bsky.social
www.thelancet.com/journals/lan...
#TBSky #IDSky @lancetmicrobe.bsky.social
www.thelancet.com/journals/lan...
Fluorescent acid-fast stains for diagnosing mycobacteria and beyond: back to the future?
Acid-fast stains (AFS) remain indispensable in modern diagnostic microbiology; they
are used for detecting mycobacteria (including Mycobacterium tuberculosis and Mycobacterium
leprae), acid-fast paras...
www.thelancet.com
October 25, 2025 at 6:40 PM
Ok, I've learned something new - acid fast stains bind nucleic acids and not mycolic acid on mycobacterial cell wall. The lipid-rich cell wall simply prevents acid-alcohol decolourisation, hence acid -fast.
#TBSky #IDSky @lancetmicrobe.bsky.social
www.thelancet.com/journals/lan...
#TBSky #IDSky @lancetmicrobe.bsky.social
www.thelancet.com/journals/lan...
Radiographic Manifestations of Tuberculosis: A Primer for Clinicians, Second Edition
Order a printed book (free, within the United States) or download the PDF: www.currytbcenter.ucsf.edu/products/vie...
#Tuberculosis #TBSky #Radiology
Order a printed book (free, within the United States) or download the PDF: www.currytbcenter.ucsf.edu/products/vie...
#Tuberculosis #TBSky #Radiology
October 21, 2025 at 9:36 PM
Radiographic Manifestations of Tuberculosis: A Primer for Clinicians, Second Edition
Order a printed book (free, within the United States) or download the PDF: www.currytbcenter.ucsf.edu/products/vie...
#Tuberculosis #TBSky #Radiology
Order a printed book (free, within the United States) or download the PDF: www.currytbcenter.ucsf.edu/products/vie...
#Tuberculosis #TBSky #Radiology
Interesting different levels of virulence comparing organisms across a broad range of the Mycobacterium tuberculosis complex (MTBC).
@pnas.org @mbehr-mcgill.bsky.social #TBSky
www.pnas.org/doi/10.1073/...
@pnas.org @mbehr-mcgill.bsky.social #TBSky
www.pnas.org/doi/10.1073/...
Virulence hierarchies within the Mycobacterium tuberculosis complex | PNAS
The Mycobacterium tuberculosis complex (MTBC) includes M. tuberculosis (M. tb), the
primary cause of human tuberculosis, M. bovis, the classical zo...
www.pnas.org
October 19, 2025 at 10:47 AM
Interesting different levels of virulence comparing organisms across a broad range of the Mycobacterium tuberculosis complex (MTBC).
@pnas.org @mbehr-mcgill.bsky.social #TBSky
www.pnas.org/doi/10.1073/...
@pnas.org @mbehr-mcgill.bsky.social #TBSky
www.pnas.org/doi/10.1073/...
Our live Q&A with Aiyana Masla is almost here! Join us Tuesday at 4 pm ET/1 pm PT to get YOUR questions about The Underdream answered by the poet herself! Don't forget to vote for your favorite questions in the #TBReaders discord!
Learn more here: tbfighters.org/book-...
#TBSky #Poetry
Learn more here: tbfighters.org/book-...
#TBSky #Poetry
October 19, 2025 at 9:09 PM
Our live Q&A with Aiyana Masla is almost here! Join us Tuesday at 4 pm ET/1 pm PT to get YOUR questions about The Underdream answered by the poet herself! Don't forget to vote for your favorite questions in the #TBReaders discord!
Learn more here: tbfighters.org/book-...
#TBSky #Poetry
Learn more here: tbfighters.org/book-...
#TBSky #Poetry
Interesting idea / biology potentially but this feels unlikely to be highly discriminatory and thus converted to a useful diagnostic!
#IDSky #TBSky #MedSky
#IDSky #TBSky #MedSky
Distinguishing tuberculosis from non-tuberculous mycobacteria and other respiratory conditions by microbiome patterns - Scientific Reports
Scientific Reports - Distinguishing tuberculosis from non-tuberculous mycobacteria and other respiratory conditions by microbiome patterns
www.nature.com
October 19, 2025 at 10:20 AM
October 9, 2025 at 11:34 AM
In two weeks, #TBReaders will host a live Q&A with author, artist, and TB survivor Aiyana Masla about The Underdream. Her poetry collection expertly paints the despair of chronic illness with a tiny thread of joy woven through.
Learn more here: tbfighters.org/book-...
#TBSky #Poetry
Learn more here: tbfighters.org/book-...
#TBSky #Poetry
October 10, 2025 at 12:07 AM
In two weeks, #TBReaders will host a live Q&A with author, artist, and TB survivor Aiyana Masla about The Underdream. Her poetry collection expertly paints the despair of chronic illness with a tiny thread of joy woven through.
Learn more here: tbfighters.org/book-...
#TBSky #Poetry
Learn more here: tbfighters.org/book-...
#TBSky #Poetry
Great job @sarasuliman.bsky.social on discussing the evolution of Mycobacterium tuberculosis in human populations over time
#TBSky #IDSky #MedSky 🧪 #genetics
www.nature.com/articles/s41...
#TBSky #IDSky #MedSky 🧪 #genetics
www.nature.com/articles/s41...
The evolution of Mycobacterium tuberculosis as humans migrated out of Africa - Nature Reviews Genetics
Sara Suliman describes a seminal 2013 publication by Comas et al. that investigated the origins of the tuberculosis-causing bacteria and its coevolution with diverse human populations.
www.nature.com
October 2, 2025 at 8:12 PM
Great job @sarasuliman.bsky.social on discussing the evolution of Mycobacterium tuberculosis in human populations over time
#TBSky #IDSky #MedSky 🧪 #genetics
www.nature.com/articles/s41...
#TBSky #IDSky #MedSky 🧪 #genetics
www.nature.com/articles/s41...
Host-directed therapies for infectious disease are here & coming!
Simple equation proposed to consider best interventions:
⭐ Microorganism + immune response = clinical presentation/status ⭐
Will require futuristic-sounding real-time diagnostics = exciting!
#IDSky #MedSky #ImmunoSky #TBSky
Simple equation proposed to consider best interventions:
⭐ Microorganism + immune response = clinical presentation/status ⭐
Will require futuristic-sounding real-time diagnostics = exciting!
#IDSky #MedSky #ImmunoSky #TBSky
The Changing Paradigm in Infectious Diseases - Host-Directed Medicine: Implications for the Next Generation of ID Physicians
academic.oup.com
October 1, 2025 at 8:43 AM
Host-directed therapies for infectious disease are here & coming!
Simple equation proposed to consider best interventions:
⭐ Microorganism + immune response = clinical presentation/status ⭐
Will require futuristic-sounding real-time diagnostics = exciting!
#IDSky #MedSky #ImmunoSky #TBSky
Simple equation proposed to consider best interventions:
⭐ Microorganism + immune response = clinical presentation/status ⭐
Will require futuristic-sounding real-time diagnostics = exciting!
#IDSky #MedSky #ImmunoSky #TBSky
Good title this:
"Tuberculosis and the perils of historical amnesia"
Good reminder about "...the enduring role of poverty, overcrowding, and substandard housing in sustaining tuberculosis in the present era.."
#TBSky #IDSky @lancetmicrobe.bsky.social
"Tuberculosis and the perils of historical amnesia"
Good reminder about "...the enduring role of poverty, overcrowding, and substandard housing in sustaining tuberculosis in the present era.."
#TBSky #IDSky @lancetmicrobe.bsky.social
Tuberculosis and the perils of historical amnesia
In a recent Comment published in The Lancet, Hans Henri P Kluge emphasised the urgency of addressing drug-resistant tuberculosis in the WHO European region.1 Although the health security framing…
www.thelancet.com
September 30, 2025 at 8:49 AM
Good title this:
"Tuberculosis and the perils of historical amnesia"
Good reminder about "...the enduring role of poverty, overcrowding, and substandard housing in sustaining tuberculosis in the present era.."
#TBSky #IDSky @lancetmicrobe.bsky.social
"Tuberculosis and the perils of historical amnesia"
Good reminder about "...the enduring role of poverty, overcrowding, and substandard housing in sustaining tuberculosis in the present era.."
#TBSky #IDSky @lancetmicrobe.bsky.social
Congrats to the Carpenter Lab on this exciting study!
I might now sound like a broken record, but check the abstract!!!
Let’s go type 7 secretion system substrates! #tuberculosis #tbsky
I might now sound like a broken record, but check the abstract!!!
Let’s go type 7 secretion system substrates! #tuberculosis #tbsky
September 25, 2025 at 11:50 AM
Congrats to the Carpenter Lab on this exciting study!
I might now sound like a broken record, but check the abstract!!!
Let’s go type 7 secretion system substrates! #tuberculosis #tbsky
I might now sound like a broken record, but check the abstract!!!
Let’s go type 7 secretion system substrates! #tuberculosis #tbsky
🌏As part of the KNCV ACTS Project, our colleague and Tech. Director, Agnes Gebhard recently visited #Indonesia during the NTP review and engaged with local teams to support country-led #TB response initiatives.
Learn more here: www.linkedin.com/feed/update/...
#TBSky
Learn more here: www.linkedin.com/feed/update/...
#TBSky
September 18, 2025 at 10:35 AM
🌏As part of the KNCV ACTS Project, our colleague and Tech. Director, Agnes Gebhard recently visited #Indonesia during the NTP review and engaged with local teams to support country-led #TB response initiatives.
Learn more here: www.linkedin.com/feed/update/...
#TBSky
Learn more here: www.linkedin.com/feed/update/...
#TBSky
OMG OMG OMG it's here
Please join us starting at 11am EDT/8 am PDT
@pidsociety.bsky.social @idsainfo.bsky.social @apha.org @hivma.bsky.social @pih.org @amfarofficial.bsky.social and over 30 other endorsing organizations
#HIV #research #NIH #IDSky #TBSky #PedsID
Please join us starting at 11am EDT/8 am PDT
@pidsociety.bsky.social @idsainfo.bsky.social @apha.org @hivma.bsky.social @pih.org @amfarofficial.bsky.social and over 30 other endorsing organizations
#HIV #research #NIH #IDSky #TBSky #PedsID
September 16, 2025 at 12:57 PM
OMG OMG OMG it's here
Please join us starting at 11am EDT/8 am PDT
@pidsociety.bsky.social @idsainfo.bsky.social @apha.org @hivma.bsky.social @pih.org @amfarofficial.bsky.social and over 30 other endorsing organizations
#HIV #research #NIH #IDSky #TBSky #PedsID
Please join us starting at 11am EDT/8 am PDT
@pidsociety.bsky.social @idsainfo.bsky.social @apha.org @hivma.bsky.social @pih.org @amfarofficial.bsky.social and over 30 other endorsing organizations
#HIV #research #NIH #IDSky #TBSky #PedsID
Interesting - small study but oral rinse looks more sensitive that facemasks to detect M tuberculosis in cases of symptomatic pulmonary TB
#TBSky #IDSky
www.atsjournals.org/doi/10.1164/...
#TBSky #IDSky
www.atsjournals.org/doi/10.1164/...
Oral Rinse versus Facemask Capture for Non-Sputum Diagnosis of Pulmonary Tuberculosis | American Journal of Respiratory and Critical Care Medicine | Articles in Press
Click to see any corrections or updates and to confirm this is the authentic version of record
www.atsjournals.org
September 14, 2025 at 2:18 PM
Interesting - small study but oral rinse looks more sensitive that facemasks to detect M tuberculosis in cases of symptomatic pulmonary TB
#TBSky #IDSky
www.atsjournals.org/doi/10.1164/...
#TBSky #IDSky
www.atsjournals.org/doi/10.1164/...
MTBC members M tuberculosis (the OG) and M bovis
#IDsky #ClinMicro #TBsky
www.etsy.com/shop/Microbe...
#IDsky #ClinMicro #TBsky
www.etsy.com/shop/Microbe...
September 13, 2025 at 4:20 PM
MTBC members M tuberculosis (the OG) and M bovis
#IDsky #ClinMicro #TBsky
www.etsy.com/shop/Microbe...
#IDsky #ClinMicro #TBsky
www.etsy.com/shop/Microbe...
This is quite cool!
"the AveloMask Kit, a user-friendly, non-invasive face mask that captures exhaled aerosols and transfers them into a buffer tube for molecular detection of respiratory tract infections"
#IDSky #ClinMicro #TBSky
journals.asm.org/doi/10.1128/...
"the AveloMask Kit, a user-friendly, non-invasive face mask that captures exhaled aerosols and transfers them into a buffer tube for molecular detection of respiratory tract infections"
#IDSky #ClinMicro #TBSky
journals.asm.org/doi/10.1128/...
AveloMask, a novel breath aerosol collection kit for airborne Mycobacterium tuberculosis: a proof-of-principle assessment | Journal of Clinical Microbiology
Tuberculosis (TB) remains the world’s deadliest infectious disease, yet diagnosis still relies heavily on sputum, which many patients struggle to produce. This study introduces the AveloMask Kit, a…
journals.asm.org
September 13, 2025 at 3:10 PM
This is quite cool!
"the AveloMask Kit, a user-friendly, non-invasive face mask that captures exhaled aerosols and transfers them into a buffer tube for molecular detection of respiratory tract infections"
#IDSky #ClinMicro #TBSky
journals.asm.org/doi/10.1128/...
"the AveloMask Kit, a user-friendly, non-invasive face mask that captures exhaled aerosols and transfers them into a buffer tube for molecular detection of respiratory tract infections"
#IDSky #ClinMicro #TBSky
journals.asm.org/doi/10.1128/...
We look forward to seeing many of you in-person or online on Monday for World TB Day!
www.currytbcenter.ucsf.edu/trainings/20...
#EndTB #WorldTBDay #UCSFWorldTBDay #WorldTBDay2025 #TBSky
www.currytbcenter.ucsf.edu/trainings/20...
#EndTB #WorldTBDay #UCSFWorldTBDay #WorldTBDay2025 #TBSky
2025 UCSF World TB Day Symposium | Curry International Tuberculosis Center
www.currytbcenter.ucsf.edu
March 21, 2025 at 10:25 PM
We look forward to seeing many of you in-person or online on Monday for World TB Day!
www.currytbcenter.ucsf.edu/trainings/20...
#EndTB #WorldTBDay #UCSFWorldTBDay #WorldTBDay2025 #TBSky
www.currytbcenter.ucsf.edu/trainings/20...
#EndTB #WorldTBDay #UCSFWorldTBDay #WorldTBDay2025 #TBSky
www.nature.com/articles/d41...
#IDSky #TBSky #HIV #malaria #Infections #PedIDSky #USAID #NIH #Health #Medicine
#IDSky #TBSky #HIV #malaria #Infections #PedIDSky #USAID #NIH #Health #Medicine
How the NIH dominates the world’s health research — in charts
Abrupt cuts by the Trump administration to the US National Institutes of Health threaten progress in medical research globally.
www.nature.com
March 12, 2025 at 8:48 AM
Hi @esmyco.bsky.social!!
Many of us are here. There is a nice starter pack by @oneyrolles.bsky.social to follow. And a #tuberculosis feed you can use by tagging that or #TBsky.
Many of us are here. There is a nice starter pack by @oneyrolles.bsky.social to follow. And a #tuberculosis feed you can use by tagging that or #TBsky.
feed.you
January 30, 2025 at 12:33 AM
Hi @esmyco.bsky.social!!
Many of us are here. There is a nice starter pack by @oneyrolles.bsky.social to follow. And a #tuberculosis feed you can use by tagging that or #TBsky.
Many of us are here. There is a nice starter pack by @oneyrolles.bsky.social to follow. And a #tuberculosis feed you can use by tagging that or #TBsky.
Optimising the use of currently available treatments through treatment stratification could reduce treatment duration by 2-months for the majority. TB treatment stratification strategies should be prospectively trialled in a phase III RCT.
#TBSky
#TBSky
June 13, 2025 at 8:25 AM
Optimising the use of currently available treatments through treatment stratification could reduce treatment duration by 2-months for the majority. TB treatment stratification strategies should be prospectively trialled in a phase III RCT.
#TBSky
#TBSky
#TBSky #IDSky
why is cavitary pulmonary TB dz thought to have a higher risk of transmission than noncavitary dz?
- tendency toward ↑ bacillary (bacterial) load in cavity
- tendency toward sputum smear positivity
- higher risk of relapse & treatment failure
www.sciencedirect.com/science/arti...
why is cavitary pulmonary TB dz thought to have a higher risk of transmission than noncavitary dz?
- tendency toward ↑ bacillary (bacterial) load in cavity
- tendency toward sputum smear positivity
- higher risk of relapse & treatment failure
www.sciencedirect.com/science/arti...
December 7, 2024 at 4:31 PM
#TBSky #IDSky
why is cavitary pulmonary TB dz thought to have a higher risk of transmission than noncavitary dz?
- tendency toward ↑ bacillary (bacterial) load in cavity
- tendency toward sputum smear positivity
- higher risk of relapse & treatment failure
www.sciencedirect.com/science/arti...
why is cavitary pulmonary TB dz thought to have a higher risk of transmission than noncavitary dz?
- tendency toward ↑ bacillary (bacterial) load in cavity
- tendency toward sputum smear positivity
- higher risk of relapse & treatment failure
www.sciencedirect.com/science/arti...
The #Stool4TB Consortium has completed their cohort recruitment!
The final numbers for their paediatric and adult cohorts stand at 1290 and 677 participants respectively. We are energized by the community's willingness to join us on our journey to #EndTB #Tuberculosis!
Read more: stool4tb.org
The final numbers for their paediatric and adult cohorts stand at 1290 and 677 participants respectively. We are energized by the community's willingness to join us on our journey to #EndTB #Tuberculosis!
Read more: stool4tb.org
January 17, 2025 at 7:59 PM