- Stool homogenates from neonates exposed to #SARSCoV2 elicited inflammatory cytokines such as IL-6 & interferon-gamma
- Similar associations between viral infections & NEC have been documented for #rotavirus, #cytomegalovirus, #norovirus & #astrovirus,
- Similar associations between viral infections & NEC have been documented for #rotavirus, #cytomegalovirus, #norovirus & #astrovirus,
December 16, 2025 at 9:10 PM
- Stool homogenates from neonates exposed to #SARSCoV2 elicited inflammatory cytokines such as IL-6 & interferon-gamma
- Similar associations between viral infections & NEC have been documented for #rotavirus, #cytomegalovirus, #norovirus & #astrovirus,
- Similar associations between viral infections & NEC have been documented for #rotavirus, #cytomegalovirus, #norovirus & #astrovirus,
-Vaccination alone in individuals not previously exposed to #SARSCoV2 generally induces minimal mucosal sIgA, while those with prior infection show more effective SIgA induction after
link.springer.com/article/10.1...
link.springer.com/article/10.1...
link.springer.com/article/10.1...
link.springer.com/article/10.1...
SIgA in various pulmonary diseases - European Journal of Medical Research
Secretory immunoglobulin A (SIgA) is one of the most abundant immunoglobulin subtypes among mucosa, which plays an indispensable role in the first-line protection against invading pathogens and antige...
link.springer.com
December 2, 2025 at 8:18 AM
-Vaccination alone in individuals not previously exposed to #SARSCoV2 generally induces minimal mucosal sIgA, while those with prior infection show more effective SIgA induction after
link.springer.com/article/10.1...
link.springer.com/article/10.1...
link.springer.com/article/10.1...
link.springer.com/article/10.1...
Thanks for giving us the breakdown. It's a surprising...and fascinating string of events. Any idea if the mRNA vaccine...along with presenting Spike protein via synthesis... also stimulates the same cascade of events enhancing T cell activity when exposed to SarsCov2?
October 26, 2025 at 2:29 AM
Thanks for giving us the breakdown. It's a surprising...and fascinating string of events. Any idea if the mRNA vaccine...along with presenting Spike protein via synthesis... also stimulates the same cascade of events enhancing T cell activity when exposed to SarsCov2?
In new review @jhumimmunity.org, Andreakos et al. report the progress of the COVID Human Genetic Effort since its launch 5 years ago, with the aim to understand clinical variability, from resistance to severe outcomes, among individuals exposed to #SARSCoV2. rupress.org/jhi/article/...
October 24, 2025 at 5:45 PM
In new review @jhumimmunity.org, Andreakos et al. report the progress of the COVID Human Genetic Effort since its launch 5 years ago, with the aim to understand clinical variability, from resistance to severe outcomes, among individuals exposed to #SARSCoV2. rupress.org/jhi/article/...
Their goal was to explain the clinical variability among #SARSCoV2-exposed individuals by searching for monogenic inborn errors of immunity and their phenocopies. The #COVID Human Genetic Effort deciphered & defined the pathogenesis of critical #COVID , MIS-C in ~ 15% & 2% of cases, respectively.
October 24, 2025 at 5:13 PM
Their goal was to explain the clinical variability among #SARSCoV2-exposed individuals by searching for monogenic inborn errors of immunity and their phenocopies. The #COVID Human Genetic Effort deciphered & defined the pathogenesis of critical #COVID , MIS-C in ~ 15% & 2% of cases, respectively.
#Medsky🧪 #IDSky #immunosky #publichealth
@casanovalab.bsky.social @petterbrodin.bsky.social et al
A global effort to define the human genetics of protective immunity to #SARSCoV2 infection & the clinical variability among #COVID- exposed individuals.
@casanovalab.bsky.social @petterbrodin.bsky.social et al
A global effort to define the human genetics of protective immunity to #SARSCoV2 infection & the clinical variability among #COVID- exposed individuals.
In this review, Andreakos et al. report the progress of the COVID Human Genetic Effort since its launch 5 years ago, with the aim to understand clinical variability, from resistance to severe outcomes, among individuals exposed to #SARSCoV2. rupress.org/jhi/article/...
#InbornErrorsOfImmunity
#InbornErrorsOfImmunity
October 24, 2025 at 5:00 PM
#Medsky🧪 #IDSky #immunosky #publichealth
@casanovalab.bsky.social @petterbrodin.bsky.social et al
A global effort to define the human genetics of protective immunity to #SARSCoV2 infection & the clinical variability among #COVID- exposed individuals.
@casanovalab.bsky.social @petterbrodin.bsky.social et al
A global effort to define the human genetics of protective immunity to #SARSCoV2 infection & the clinical variability among #COVID- exposed individuals.
In this review, Andreakos et al. report the progress of the COVID Human Genetic Effort since its launch 5 years ago, with the aim to understand clinical variability, from resistance to severe outcomes, among individuals exposed to #SARSCoV2. rupress.org/jhi/article/...
#InbornErrorsOfImmunity
#InbornErrorsOfImmunity
October 24, 2025 at 4:32 PM
In this review, Andreakos et al. report the progress of the COVID Human Genetic Effort since its launch 5 years ago, with the aim to understand clinical variability, from resistance to severe outcomes, among individuals exposed to #SARSCoV2. rupress.org/jhi/article/...
#InbornErrorsOfImmunity
#InbornErrorsOfImmunity
I know of a mother who under the social pressures and from what I understood pressure from her husband dropped all precautions. Her child was exposed to sarscov2 and was admitted to hospital with severe seizures after infection. She knows of longcovid.
But all caution went.
Heartbreaking.
But all caution went.
Heartbreaking.
August 8, 2025 at 10:27 AM
I know of a mother who under the social pressures and from what I understood pressure from her husband dropped all precautions. Her child was exposed to sarscov2 and was admitted to hospital with severe seizures after infection. She knows of longcovid.
But all caution went.
Heartbreaking.
But all caution went.
Heartbreaking.
And after schoolteachers and healthcare workers, the part of the population most exposed to sarscov2 is children.
What will be the result of a life with 2 or more sarscov2 infections annually in to their lifetimes.
Nothing good.
What will be the result of a life with 2 or more sarscov2 infections annually in to their lifetimes.
Nothing good.
August 8, 2025 at 5:06 AM
And after schoolteachers and healthcare workers, the part of the population most exposed to sarscov2 is children.
What will be the result of a life with 2 or more sarscov2 infections annually in to their lifetimes.
Nothing good.
What will be the result of a life with 2 or more sarscov2 infections annually in to their lifetimes.
Nothing good.
#Medsky🧪#IDsky #virosky #immunosky #publichealth #SARSCoV2 infection can lead to persistent pulmonary sequelae ( #Longcovid ), particularly among workers exposed to occupational stressors like high altitude.
Post-COVID Spirometric Abnormalities in Workers with Intermittent High-Altitude Exposure: A Cross-Sectional Study in Peru https://www.medrxiv.org/content/10.1101/2025.08.01.25332622v1
August 3, 2025 at 5:40 PM
#Medsky🧪#IDsky #virosky #immunosky #publichealth #SARSCoV2 infection can lead to persistent pulmonary sequelae ( #Longcovid ), particularly among workers exposed to occupational stressors like high altitude.
Vaccination against #SARSCoV2 should be prioritized in
subjects with a high BMI, especially in highly exposed workers, such as health workers. @mdpiopenaccess.bsky.social
www.mdpi.com/2076-393X/13...
PDF
mdpi-res.com/d_attachment...
subjects with a high BMI, especially in highly exposed workers, such as health workers. @mdpiopenaccess.bsky.social
www.mdpi.com/2076-393X/13...
mdpi-res.com/d_attachment...
June 20, 2025 at 9:41 AM
Vaccination against #SARSCoV2 should be prioritized in
subjects with a high BMI, especially in highly exposed workers, such as health workers. @mdpiopenaccess.bsky.social
www.mdpi.com/2076-393X/13...
PDF
mdpi-res.com/d_attachment...
subjects with a high BMI, especially in highly exposed workers, such as health workers. @mdpiopenaccess.bsky.social
www.mdpi.com/2076-393X/13...
mdpi-res.com/d_attachment...
1000s May Have Been Exposed To A Contagious Virus At 2 Major Airports!
www.youtube.com/watch?v=GHHh...
#COVID19 #SARSCoV2 #Pandemic #CovidIsNotOver #CovidIsAirborne #H5N1 #Measles #WhoopingCough #RSV #Norovirus #Tuberculosis #Polio #Mpox #MaskUp #N95 #KeepMasksInHealthcare
www.youtube.com/watch?v=GHHh...
#COVID19 #SARSCoV2 #Pandemic #CovidIsNotOver #CovidIsAirborne #H5N1 #Measles #WhoopingCough #RSV #Norovirus #Tuberculosis #Polio #Mpox #MaskUp #N95 #KeepMasksInHealthcare
1000s May Have Been Exposed To A Contagious Virus At 2 Major Airports!
YouTube video by Data Report
www.youtube.com
June 17, 2025 at 12:16 AM
1000s May Have Been Exposed To A Contagious Virus At 2 Major Airports!
www.youtube.com/watch?v=GHHh...
#COVID19 #SARSCoV2 #Pandemic #CovidIsNotOver #CovidIsAirborne #H5N1 #Measles #WhoopingCough #RSV #Norovirus #Tuberculosis #Polio #Mpox #MaskUp #N95 #KeepMasksInHealthcare
www.youtube.com/watch?v=GHHh...
#COVID19 #SARSCoV2 #Pandemic #CovidIsNotOver #CovidIsAirborne #H5N1 #Measles #WhoopingCough #RSV #Norovirus #Tuberculosis #Polio #Mpox #MaskUp #N95 #KeepMasksInHealthcare
#Medsky🧪 #IDsky #immunosky #publichealth 2 doses of AZD1222 or BNT162b2 significantly increased existing NAbTs against #SARSCoV2 in a highly exposed population & healthy adults following 2 yrs of community exposure to #COVID generates durable & broad neutralising antibodies against future variants.
May 29, 2025 at 3:10 PM
#Medsky🧪 #IDsky #immunosky #publichealth 2 doses of AZD1222 or BNT162b2 significantly increased existing NAbTs against #SARSCoV2 in a highly exposed population & healthy adults following 2 yrs of community exposure to #COVID generates durable & broad neutralising antibodies against future variants.
How people and/or farmed animals were exposed to an insectivorous bat coronavirus is the central question and it's not being asked.
www.sciencedirect.com/science/arti...
#OriginofCovid #SARSCoV2 #Coronavirus #China
www.sciencedirect.com/science/arti...
#OriginofCovid #SARSCoV2 #Coronavirus #China
The recency and geographical origins of the bat viruses ancestral to SARS-CoV and SARS-CoV-2
The emergence of SARS-CoV in 2002 and SARS-CoV-2 in 2019 led to increased sampling of sarbecoviruses circulating in horseshoe bats. Employing phylogen…
www.sciencedirect.com
May 12, 2025 at 12:43 PM
How people and/or farmed animals were exposed to an insectivorous bat coronavirus is the central question and it's not being asked.
www.sciencedirect.com/science/arti...
#OriginofCovid #SARSCoV2 #Coronavirus #China
www.sciencedirect.com/science/arti...
#OriginofCovid #SARSCoV2 #Coronavirus #China
Chilblains were reported in #SARSCoV2–exposed individuals without PCR- or serologically defined #COVID19. Saidoune, Gilliet , @ahmad-yatim.bsky.social et al. show that excessive TLR7 responses to SARS-CoV-2 by pDCs are linked to I-IFN–driven chilblain development. rupress.org/jem/article/...
April 14, 2025 at 4:21 PM
Chilblains were reported in #SARSCoV2–exposed individuals without PCR- or serologically defined #COVID19. Saidoune, Gilliet , @ahmad-yatim.bsky.social et al. show that excessive TLR7 responses to SARS-CoV-2 by pDCs are linked to I-IFN–driven chilblain development. rupress.org/jem/article/...
A pill to prevent #Covid is showing promise in Japan. The drug is made by pharmaceutical giant Shionogi. Researchers say the drug—ensitrelvir—blocked #SARSCoV2 among people exposed to it. Ensitrelvir is approved in Japan at a lower dose, which helps reduce hospitalizations time.com/7267886/pill...
A Pill to Prevent COVID-19 Shows Promise
Results from a late-stage study on the new drug ensitrelvir are encouraging.
time.com
March 18, 2025 at 4:21 PM
A pill to prevent #Covid is showing promise in Japan. The drug is made by pharmaceutical giant Shionogi. Researchers say the drug—ensitrelvir—blocked #SARSCoV2 among people exposed to it. Ensitrelvir is approved in Japan at a lower dose, which helps reduce hospitalizations time.com/7267886/pill...
Were raccoon dogs or some other animal at the Wuhan market the spark that set off a worldwide conflagration? It first has to be asked is how were any of the livestock exposed to a coronavirus laden bat from the south of China? Raccoon dogs were likely raised near Wuhan. #SARSCoV2 #OriginOfCoViD
March 15, 2025 at 2:50 PM
Were raccoon dogs or some other animal at the Wuhan market the spark that set off a worldwide conflagration? It first has to be asked is how were any of the livestock exposed to a coronavirus laden bat from the south of China? Raccoon dogs were likely raised near Wuhan. #SARSCoV2 #OriginOfCoViD
Thanks to Ed for this detailed breakdown. Among other things, this illustrates the problem of differentiating any post-vaccine syndrome from an exacerbation of #PASC when almost everyone has been exposed to #SARSCoV2 itself
deplatformdisease.substack.com/p/that-post-...
deplatformdisease.substack.com/p/that-post-...
That "post-vaccine syndrome" preprint everyone is talking about
There are major issues with the conclusions being drawn from it.
deplatformdisease.substack.com
February 25, 2025 at 10:21 AM
Thanks to Ed for this detailed breakdown. Among other things, this illustrates the problem of differentiating any post-vaccine syndrome from an exacerbation of #PASC when almost everyone has been exposed to #SARSCoV2 itself
deplatformdisease.substack.com/p/that-post-...
deplatformdisease.substack.com/p/that-post-...
He was exposed to SARSCOV2
I didn't see masks around him
#Himmelfahrt ...
Now they say: he is old, that's normal to have these complex stuff. 😜
I didn't see masks around him
#Himmelfahrt ...
Now they say: he is old, that's normal to have these complex stuff. 😜
Pope Francis will remain in a Rome hospital after being admitted late last week following a series of tests that indicated a “complex clinical picture,” the Vatican said on Monday, raising new concerns about the 88-year-old's health.
Pope Francis Will Remain in Hospital for ‘Complex’ Clinical Issue
Pope Francis was admitted on Friday with a respiratory infection. The announcement on Monday did not provide further detail, but raised fresh concerns about the pontiff’s health.
nyti.ms
February 17, 2025 at 3:36 PM
He was exposed to SARSCOV2
I didn't see masks around him
#Himmelfahrt ...
Now they say: he is old, that's normal to have these complex stuff. 😜
I didn't see masks around him
#Himmelfahrt ...
Now they say: he is old, that's normal to have these complex stuff. 😜
Wonder how many SARSCOV2 infections he exposed himself to
February 17, 2025 at 8:48 AM
Wonder how many SARSCOV2 infections he exposed himself to
and it is reasonable to assume that almost the entire world population has been exposed to viral antigen . in this study that #SARSCoV2 evolution is driven by infection hx & the ability of elicited humoral immunity to cross-neutralize emerging variants
www.nature.com/articles/s41...
www.nature.com/articles/s41...
SARS-CoV-2 evolution on a dynamic immune landscape - Nature
A modelling approach predicts SARS-CoV-2 variant dynamics on the basis of immunity and cross-neutralization, which was shaped by a region’s SARS-CoV-2 infection history.
www.nature.com
January 29, 2025 at 9:01 PM
and it is reasonable to assume that almost the entire world population has been exposed to viral antigen . in this study that #SARSCoV2 evolution is driven by infection hx & the ability of elicited humoral immunity to cross-neutralize emerging variants
www.nature.com/articles/s41...
www.nature.com/articles/s41...
it's not twitter it's simply denial- 😳
most parents can not imagine covid sequelae in 15 years for their children which are exposed multiple times to SarsCov2-
😪 self soothing talks h/t @njbbari3.bsky.social
Neil Stone, Michael Mina, Jeremy Kamil and many more got babies the last years ...
👀
most parents can not imagine covid sequelae in 15 years for their children which are exposed multiple times to SarsCov2-
😪 self soothing talks h/t @njbbari3.bsky.social
Neil Stone, Michael Mina, Jeremy Kamil and many more got babies the last years ...
👀
One reason Twitter is so shit, @kentparkskeet.bsky.social
January 8, 2025 at 12:12 PM
it's not twitter it's simply denial- 😳
most parents can not imagine covid sequelae in 15 years for their children which are exposed multiple times to SarsCov2-
😪 self soothing talks h/t @njbbari3.bsky.social
Neil Stone, Michael Mina, Jeremy Kamil and many more got babies the last years ...
👀
most parents can not imagine covid sequelae in 15 years for their children which are exposed multiple times to SarsCov2-
😪 self soothing talks h/t @njbbari3.bsky.social
Neil Stone, Michael Mina, Jeremy Kamil and many more got babies the last years ...
👀
We should be very concerned about a virus that can change the structure of the brain. Especially in children whose brains are developing and growing, we do not know the long term ramifications of allowing children to be exposed to SARSCoV2 repeatedly but the research is concerning.
December 30, 2024 at 11:51 PM
We should be very concerned about a virus that can change the structure of the brain. Especially in children whose brains are developing and growing, we do not know the long term ramifications of allowing children to be exposed to SARSCoV2 repeatedly but the research is concerning.
“ #COVID exposed how dependent our Economy was on the International Supply Chain.
I’ve invested in American Manufacturing.
American Farmers are just as dependent on Chip Manufacturing as Corporations.
We need a strong Middle Class with Good Paying Jobs.”
President Joe Biden
CSPAN
#SARSCoV2
I’ve invested in American Manufacturing.
American Farmers are just as dependent on Chip Manufacturing as Corporations.
We need a strong Middle Class with Good Paying Jobs.”
President Joe Biden
CSPAN
#SARSCoV2
December 10, 2024 at 6:52 PM
#MedSky🧪#IDSky Obesity and age are transmission risk factors for #SARSCoV2 infection among exposed individuals
academic.oup.com/pnasnexus/ar...
academic.oup.com/pnasnexus/ar...
Obesity and age are transmission risk factors for SARS-CoV-2 infection among exposed individuals
Abstract. The coronavirus disease (COVID-19) pandemic has occurred in Massachusetts in multiple waves led by a series of emerging variants. While the evide
academic.oup.com
August 27, 2024 at 11:18 PM
#MedSky🧪#IDSky Obesity and age are transmission risk factors for #SARSCoV2 infection among exposed individuals
academic.oup.com/pnasnexus/ar...
academic.oup.com/pnasnexus/ar...