#RNATherapeutics
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invernatx.com
Exciting news from Inverna ! 🎉

www.linkedin.com/posts/invern...
#RNATherapeutics #Pseudoexon #ASO #Innovation
Inverna Therapeutics announces the formation of its Scientific Advisory Board consisting of world-renowned leaders in RNA therapeutics and neurodegenerative research | Inverna Therapeutics
Inverna Therapeutics is delighted to announce the formation of our new Scientific Advisory Board (SAB)🚀 We welcome world-renowned leaders in RNA therapeutics and neurodegenerative research to advance...
www.linkedin.com
October 29, 2025 at 8:45 AM
rti-umasschan.bsky.social
Make an impact: UMassChan & the RTI are seeking junior scientists for our Maraganore Early Independence Fellows Program (go.umassmed.edu/RTI-Maragano...)

Priority Deadline: December 1, 2024

Please share with your networks!
#AcademicChatter #AcademicJobs #FacultyJobs #RNATherapeutics
RTI Maraganore Early Independence Fellows banner. Academic appt: Asst Prof (NTT); Annual support of $440k; career development through iCAP; childcare supplement of $10k. Eligibility, must be >24months post-completion of terminal degree (PhD or MD/PhD)
November 12, 2024 at 3:19 PM
feichtenschlager.bsky.social
Excited to share our latest research on targeting NRAS-mutant melanoma. We used antisense oligonucleotides (ASOs) to directly suppress NRAS-mRNA
Grateful to my amazing co-authors and collaborators who made this possible!
www.nature.com/articles/s43...
#Melanoma #NRAS #ASO #RNAtherapeutics #OrtizLab
LinkedIn
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lnkd.in
June 5, 2025 at 5:36 PM
ncard-research.bsky.social
🧬 NCARD researchers are driving personalised mRNA cancer vaccine development at the Australian Centre for RNA Therapeutics.

Years of tumour research now powers cutting-edge RNA therapies! 🎯
ncard.org.au/creating-sup...
#CancerResearch #RNATherapeutics #NCARDresearch
Creating super cell power – NCARD
ncard.org.au
July 11, 2025 at 2:23 AM
rti-umasschan.bsky.social
Hot off the press from the RTI: Translon: a single term for translated regions
pubmed.ncbi.nlm.nih.gov/40890551/?ut... #RNA #RNATherapeutics
Translon: a single term for translated regions - PubMed
Translon: a single term for translated regions
pubmed.ncbi.nlm.nih.gov
September 2, 2025 at 5:02 PM
darleneryan.bsky.social
#nobelprize2023 winner, Drew Weissman, talks about the endless potential of #RNAtherapeutics in the development of #vaccines & in the treatment of many #diseases! The future is bright in #scienceresearch & #healthcare!!

#mrnavaccines #scienceandtechnology

www.linkedin.com/posts/nobelp...
The Nobel Prize on LinkedIn: “RNA therapeutics has enormous potential for vaccines, for genetic…
“RNA therapeutics has enormous potential for vaccines, for genetic diseases, for therapeutic protein delivery, for the treatment of a variety of diseases. I…
www.linkedin.com
January 13, 2024 at 3:45 PM
rti-umasschan.bsky.social
Hot off the press from the RTI: TDP-43-dependent mis-splicing of KCNQ2 triggers intrinsic neuronal hyperexcitability in ALS/FTD
buff.ly/X23QYQI #RNA #RNATherapeutics
TDP-43-dependent mis-splicing of KCNQ2 triggers intrinsic neuronal hyperexcitability in ALS/FTD - PubMed
Motor neuron hyperexcitability is a broadly observed yet poorly understood feature of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Nuclear depletion and cytoplasmic aggregation...
buff.ly
November 2, 2025 at 6:02 PM
rti-umasschan.bsky.social
Hot off the press from the RTI: Blocking somatic repeat expansion and lowering huntingtin via RNA interference synergize to prevent Huntington's disease pathogenesis in mice
pubmed.ncbi.nlm.nih.gov/40667291/?ut... #RNA #RNATherapeutics
Blocking somatic repeat expansion and lowering huntingtin via RNA interference synergize to prevent Huntington's disease pathogenesis in mice - PubMed
Huntington's disease (HD) is a progressive neurodegenerative disorder with no approved therapies. Two major molecular drivers-somatic expansion of inherited CAG repeats and toxic mutant HTT (mHTT) variants-lead...
pubmed.ncbi.nlm.nih.gov
July 30, 2025 at 5:02 PM
rti-umasschan.bsky.social
Hot off the press from the RTI: The N=1 Collaborative: advancing customized nucleic acid therapies through collaboration and data sharing
pubmed.ncbi.nlm.nih.gov/40277082/?ut... #RNA #RNATherapeutics
The N=1 Collaborative: advancing customized nucleic acid therapies through collaboration and data sharing - PubMed
Developing customized gene-targeting therapies for the millions of individuals affected by ultra-rare diseases globally requires breaking new ground in therapeutic and regulatory innovation. To address...
pubmed.ncbi.nlm.nih.gov
April 26, 2025 at 5:01 PM
martinsauvageau.bsky.social
We are looking for a talented Research Assistant to work in the #RNATherapeutics Core Facility at the @ircm.bsky.social in beautiful Montreal.

More details on the position and on how to apply here:
www.ircm.qc.ca/en/position-...
Research Assistant - RNA Therapeutics Core Facility
www.ircm.qc.ca
May 20, 2025 at 9:01 PM
rti-umasschan.bsky.social
So exciting to see Victor Ambros @vambros.bsky.social & Gary Ruvkun named two of TIME's most influential health leaders! time.com/collections/... #RNA #RNATherapeutics
TIME100 Health: Victor Ambros and Gary Ruvkun
Find out why they're on the TIME100 Health list.
time.com
May 13, 2025 at 2:19 PM
rti-umasschan.bsky.social
Hot off the press from the RTI: Albumin-binding dendritic siRNA improves delivery and efficacy to solid tumors in a melanoma model
pubmed.ncbi.nlm.nih.gov/40606645/?ut... #RNA #RNATherapeutics
Albumin-binding dendritic siRNA improves delivery and efficacy to solid tumors in a melanoma model - PubMed
Small interfering RNA (siRNA) therapeutics are a new class of drugs that is rapidly expanding to tackle various diseases. Extrahepatic delivery of siRNAs, especially to the parenchyma of solid tumors,...
pubmed.ncbi.nlm.nih.gov
July 4, 2025 at 5:03 PM
echelonbio.bsky.social
🔬 LNP Webinar Wed, Aug 13th!
"Using single cell RNA sequencing to identify novel LNP candidates"

Explore a powerful approach to overcoming key challenges in lipid nanoparticle delivery.

Save your spot 👉 events.teams.microsoft.com/event/2fa8a4...

#LipidNanoparticles #RNAtherapeutics #DrugDelivery
July 22, 2025 at 4:26 PM
rti-umasschan.bsky.social
Hot off the press from the RTI: Optimized Chemical Structure Extends Silencing Duration of Therapeutic siRNAs in Dividing Cancer and Immune Cells
pubmed.ncbi.nlm.nih.gov/40808258/?ut... #RNA #RNATherapeutics
Optimized Chemical Structure Extends Silencing Duration of Therapeutic siRNAs in Dividing Cancer and Immune Cells - PubMed
RNA interference (RNAi)-based medicines offer precise targeting of virtually any transcript, making them an appealing new drug class for immune-oncology. While RNAi therapies are highly effective in non-dividing...
pubmed.ncbi.nlm.nih.gov
August 15, 2025 at 5:06 PM
catug.bio
Congratulations to the authors Kelsey L. Swingle, Alex G. Hamilton, Drew Weissman & Michael J. Mitchell. Link to article here: www.nature.com/articles/s41...

#CATUG #Catpure #Nanomedicine #mRNA #PreEclampsia #Pharma #Biotech #LNP #RNAtherapeutics #MaternalHealth #Innovation
April 14, 2025 at 2:00 PM
miguelmontez.bsky.social
What a fabulous work! A polyA "tailored" mechanism to enhance #mRNA vaccine efficiency via cytoplasmic re-adenylation. Huge impact on #RNAtherapeutics.
A demonstration of the scientific excellence of Polish research institutions.
iimcb.bsky.social iimcb.bsky.social @iimcb.bsky.social · Apr 16
🌐Our @nature.com paper is out! Researchers from IIMCB and other Polish institutions show how TENT5A boosts mRNA vaccine efficacy by stabilizing therapeutic mRNAs and enhancing antigen production. A step toward better therapies for cancer and beyond! 🧬

👉Read the story: bit.ly/3XYvQkI

#Nature #mRNA
IIMCB
bit.ly
April 17, 2025 at 7:06 PM
rti-umasschan.bsky.social
Hot off the press from the RTI: Absolute Quantification of Mammalian MicroRNAs for Therapeutic RNA Cleavage and Detargeting
pubmed.ncbi.nlm.nih.gov/40436630/?ut... #RNA #RNATherapeutics
Absolute Quantification of Mammalian MicroRNAs for Therapeutic RNA Cleavage and Detargeting - PubMed
MicroRNAs (miRNAs) are small regulatory RNAs that destabilize partially complementary transcripts and cleave perfectly paired targets. miRNAs are often expressed in a specific tissue, allowing miRNA-directed...
pubmed.ncbi.nlm.nih.gov
May 29, 2025 at 5:03 PM
d2rmcgill.bsky.social
🌍👩‍🔬 Celebrating International Day of Women and Girls in Science!

At D2R, we champion the incredible contributions of women in #RNAtherapeutics.

Hear from researchers Lucienne Tritten & Sabina Beilstein on the importance of gender diversity in science: mcgill.ca/dna-to-rna/a...
February 11, 2025 at 1:40 PM
catug.bio
We are excited about the opportunities ahead and look forward to advancing hashtag#RNAtherapeutics through meaningful global partnerships.

Thank you Mohamed ElSayed, Ph.D. Sissi (Xi) Lin and Tommy D. for the visit, were very happy to have you.

Lin Jin, Mengfei Sun, 冯璐雯, Weicheng (Michael) Zhang
May 29, 2025 at 7:42 AM
rti-umasschan.bsky.social
🚨 New assay alert 🚨 from the Korostelev lab: Assay for ribosome stimulation of angiogenin nuclease #RNA" class="hover:underline text-blue-600 dark:text-sky-400 no-card-link" target="_blank" rel="noopener" data-link="bsky">activity
buff.ly/4ifZcCx #RNA <a href="/hashtag/RNATherapeutics" class="hover:underline text-blue-600 dark:text-sky-400 no-card-link">#RNATherapeutics #RiSANA
February 28, 2025 at 3:32 PM
cp-trendsbiochem.bsky.social
Now online - the Opinion "Small RNA and Toll-like receptor interactions: origins and disease mechanisms" from
@qichen-lab.bsky.social and co.

#sncRNA #TLR #aptamers #RNAtherapeutics #autoimmunediseases

Read it here 👉 authors.elsevier.com/a/1kcgr3S6Gf...
February 17, 2025 at 9:49 PM
rti-umasschan.bsky.social
Hot off the press from the RTI: Virion-associated influenza hemagglutinin clusters upon sialic acid binding visualized by cryoelectron tomography
pubmed.ncbi.nlm.nih.gov/40244672/?ut... #RNA #RNATherapeutics
Virion-associated influenza hemagglutinin clusters upon sialic acid binding visualized by cryoelectron tomography - PubMed
Influenza viruses are enveloped, negative-sense single-stranded RNA viruses covered in a dense layer of glycoproteins. Hemagglutinin (HA) accounts for 80 to 90% of influenza glycoprotein and plays a role...
pubmed.ncbi.nlm.nih.gov
April 18, 2025 at 5:02 PM
rti-umasschan.bsky.social
Hot off the press from the RTI: Amortized template matching of molecular conformations from cryoelectron microscopy images using simulation-based inference
pubmed.ncbi.nlm.nih.gov/40465628/?ut... #RNA #RNATherapeutics
Amortized template matching of molecular conformations from cryoelectron microscopy images using simulation-based inference - PubMed
Characterizing the conformational ensemble of biomolecular systems is key to understand their functions. Cryoelectron microscopy (cryo-EM) captures two-dimensional snapshots of biomolecular ensembles,...
pubmed.ncbi.nlm.nih.gov
June 5, 2025 at 5:02 PM
genewiz.bsky.social
Get the playbook every #RNA developer needs. Learn how to tackle key challenges in RNA design, safety and delivery with streamlined workflow and high-quality data solutions. This guide is built for scientists pushing the boundaries of #RNATherapeutics.

Grab your copy: hubs.ly/Q03z-kR60
August 21, 2025 at 7:18 PM
rti-umasschan.bsky.social
Hot off the press from the RTI: Phage SSB detection by retron Eco8 msDNA unleashes nuclease-mediated immunity
buff.ly/HXnSgjd #RNA #RNATherapeutics
Phage SSB detection by retron Eco8 msDNA unleashes nuclease-mediated immunity - PubMed
Retrons are antiphage defense systems that synthesize multicopy single-stranded DNA (msDNA) and are being adapted for genome engineering. The Escherichia coli retron Eco8 system comprises a reverse transcriptase...
buff.ly
November 2, 2025 at 6:00 PM