#PIWI
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biologyopen.bsky.social
@sciencealyssa.bsky.social, @kourtidislab.bsky.social & co investigate the PIWI-piRNA pathway in #coloncancer using a nuanced bioinformatic and cell-based approach, linking the downregulation of PIWIL2 to disease progression, transposable element activation and DNA damage. doi.org/10.1242/bio....
Representative images of Caco2+LZRS, PIWIL2 KO+LZRS and PIWIL2 KO+PIWIL2-FLAG cells grown in anchorage independent conditions after 7 days.
November 11, 2025 at 9:00 AM
cp-molcell.bsky.social
The Piwi-piRNA complex initiates transposon silencing via transcription termination factors PNUTS and Senataxin
The Piwi-piRNA complex initiates transposon silencing via transcription termination factors PNUTS and Senataxin
Wu et al. reveal that the SFiNX complex triggers transposon silencing through the association of Sov with two transcription termination factors, PNUTS and Senataxin, leading to RNA Pol II stalling. These findings suggest that piRNAs function as transcription termination signals, initiating piRNA-guided repression prior to transposon heterochromatinization.
dlvr.it
November 10, 2025 at 8:14 PM
emeraldtrinity.bsky.social
Page from Piwi, a spinoff of Helck
November 6, 2025 at 4:54 PM
krisnogud.bsky.social
Moinschön PiWi 🤗
November 6, 2025 at 6:32 AM
biorxiv-devbio.bsky.social
Spatiotemporal control of PIWI compartmentalization by mitochondrial scaffolds defines pachytene piRNA pathway organization https://www.biorxiv.org/content/10.1101/2025.11.02.684826v1
November 4, 2025 at 1:30 PM
biorxivpreprint.bsky.social
Spatiotemporal control of PIWI compartmentalization by mitochondrial scaffolds defines pachytene piRNA pathway organization https://www.biorxiv.org/content/10.1101/2025.11.02.684826v1
November 4, 2025 at 1:30 PM
fly-broadcast.bsky.social
Tethered Function Assay for Analyzing PIWI-piRNA-Mediated Co-transcriptional Silencing
#Drosophila
Tethered Function Assay for Analyzing PIWI-piRNA-Mediated Co-transcriptional Silencing #Drosophila
PubMed link
pubmed.ncbi.nlm.nih.gov
November 1, 2025 at 10:23 AM
iduncs.bsky.social
One of the few live versions of a song that I really like. Brings me sugar.

music.youtube.com/watch?v=PiWI...
Sugar (Live)
YouTube video by Tori Amos - Topic
music.youtube.com
October 31, 2025 at 6:03 PM
cp-molcell.bsky.social
Online Now: The Piwi-piRNA complex initiates transposon silencing via transcription termination factors PNUTS and Senataxin Online now:
The Piwi-piRNA complex initiates transposon silencing via transcription termination factors PNUTS and Senataxin
Wu et al. reveal that the SFiNX complex triggers transposon silencing through the association of Sov with two transcription termination factors, PNUTS and Senataxin, leading to RNA Pol II stalling. These findings suggest that piRNAs function as transcription termination signals, initiating piRNA-guided repression prior to transposon heterochromatinization.
dlvr.it
October 29, 2025 at 7:14 PM
bokuvienna.bsky.social
🌾 Planet Shapers Folge 9: Im Feldlabor - von Wetter, Wein und Wattstunden. Wie reagieren Landwirtschaft und Weinbau auf den Klimawandel? Es geht um Prognosen, PIWI-Weine und Agri-Photovoltaik. Der Podcast der BOKU University. Jetzt überall, wo es Podcasts gibt: boku.ac.at/planetshapers
October 23, 2025 at 8:39 AM
donalde.bsky.social
That was pretty much exactly my thoughts on the matter, it is a PIWI so has strong mildew resistance which is a benefit in the UK....
October 21, 2025 at 9:02 AM
pftnhr.xyz
Hochliteratur in den letzten Stunden vor der Heimfahrt. (Informationen zum Erwerb gibt’s auf piwimonium.de (http://www.piwimonium.de/#/crowdfunding/))
Das Buch »MOTÖR Eder und sein TRUEmuckl« von Christopher Tauber aka. Piwi.
October 17, 2025 at 12:51 PM
lesurath.bsky.social
Happy Birthday!
And if you ever come across this PIWI (= gung-ho-resistant vine), I highly recommend w:
October 16, 2025 at 4:03 PM
www.wein-und-markt.de
Zukunftssorten-Hotspot Berlin

https://www.wein-und-markt.de/zukunftssorten-hotspot-berlin

Mithilfe von Fachvorträgen, Masterclasses und der anschließenden Messe Piwi-Wein-Salon ist Berlin laut Organisator Piwi International der „Hotpsot für die Weine der Zukunft.“
Zukunftssorten-Hotspot Berlin
Am 8. und 9. November 2025 findet in Berlin der Piwi World Summit statt. Mithilfe von Fachvorträgen, Masterclasses und der anschließenden Messe Piwi-Wein-Salo
www.wein-und-markt.de
October 16, 2025 at 3:30 PM
86dominik.bsky.social
Ready to explore? The assembly is live on UCSC Genome Browser with our functional datasets integrated: ChIP-seq, RNA-seq, PRO-seq, and small RNA-seq. Fully annotated and ready for you to go bird watching. (4/12)
genome-euro.ucsc.edu/s/Brennecke%...
Genome browser view of the Myc-RA locus including data-tracks. The gene structure (top, blue) includes the 3' UTR end determined by direct RNA sequencing (red arrowhead). Tracks show regulatory activity (STARR-seq), chromatin accessibility (DHSseq), nascent transcription (PRO-seq), gene expression (RNA-seq), small RNA production (sRNA-seq), and chromatin marks (Pol II and H3K9me3 ChIP-seq) under control (siLuc) and Piwi knockdown (siPiwi) conditions.
October 14, 2025 at 8:34 PM
genesndiseases.bsky.social
This review explores the roles of #PIWI and #piRNAs in #disease development, highlighting their potential as therapeutic targets. #Therapeutics #medsky

#OpenAccess: www.sciencedirect.com/science/arti...
October 11, 2025 at 12:47 AM
crenquis.mstdn.io.ap.brid.gy
We've been babysitting an aunt's dog, Piwi, for a week now; he's ~22.
Carried him out back to do his morning constitutional. Poor boy walks like he just downed a bottle of whiskey.
The look is like "Dude! Put the camera away - I need to poop."

#dog #dogstodon #losangeles #olddog #chihuahua
Photo of an old chihuahua standing in profile facing the right of the frame. The dog is mostly black with tan legs and muzzle; there is a lot of grey hair mixed in on his head and muzzle. His ears are erect and he is looking sideways at the camera. The background is a messy yard with a lot of leaves, dirt, and other detritus - there are some green papaya leaves at the top of the frame.
October 8, 2025 at 5:48 PM
europesays.bsky.social
PIWI Wein

https://www.europesays.com/2475104/

Ich habe mir im Frühling diesen Wein online bestellt. Angeblich pilzresistent. Ist das die normale Verfärbung in Herbst…
PIWI Wein - EUROPE SAYS
by thoddi77
www.europesays.com
October 8, 2025 at 4:30 AM
europesays.bsky.social
PIWI Wein

https://www.europesays.com/2475104/

Ich habe mir im Frühling diesen Wein online bestellt. Angeblich pilzresistent. Ist das die normale Verfärbung in Herbst…
PIWI Wein - EUROPE SAYS
by thoddi77
www.europesays.com
October 8, 2025 at 4:30 AM
philipcball.bsky.social
And this is of course what genomes are. We do know eg that some of the transposons have to be kept in order via Piwi proteins, but the fact is that our genome as a whole does its job, and even some bits that came from viruses have a role to play in that.
October 3, 2025 at 5:36 PM
blue-fixer.bsky.social
www.youtube.com/watch?v=pIwI...

HERO ~ ! ! I'll never forget you!
Natsukashikutte Hero〜I'll Never Forget You!〜 (subtitulado al español)
YouTube video by Anime y Tokusatsu En Español
www.youtube.com
October 1, 2025 at 2:16 PM
embojournal.org
#PIWI proteins orchestrate assembly and disassembly of the piRNA biogenesis machinery, by promoting formation of electron-dense intermitochondrial cement (IMC) in murine spermatocytes
Deqiang Ding and coworkers
www.embopress.org/doi/full/10....
September 30, 2025 at 8:18 AM
cezannesales.bsky.social
Mitten im südfranzösischen Hinterland zeigt das Château Duvivier, wie moderner, nachhaltiger Weinbau aussehen kann. #Biowein #ChâteauDuvivierr #Delinat #NachhaltigerWeinbau #Piwi
www.tuttiisensi.de/?p=31260
September 18, 2025 at 12:45 PM
cezannesales.bsky.social
Mitten im südfranzösischen Hinterland zeigt das Château Duvivier, wie moderner, nachhaltiger Weinbau aussehen kann. #Biowein #ChâteauDuvivierr #Delinat #NachhaltigerWeinbau #Piwi
www.tuttiisensi.de/?p=31260
September 18, 2025 at 12:44 PM
alainkohlvirology.bsky.social
Really depends what you want to to do! Engineering viruses or just use viruses to infect mosquito cells. There’s some papers that show bunyavirus canonical piRNAs and role of piwi proteins.
September 18, 2025 at 6:43 AM