The lack of appropriate antimicrobials to tackle multidrug-resistant Gram-negative bacteria poses an escalating threat to modern medicine. Addressing this urgent issue, we have recently developed synt...

Confidence that fluids have completely exchanged in flow cells is crucial for data interpretation and reproducibility. Using a neutron reflectometry liquid flow cell as an example, this article presents a method for harnessing buoyancy effects to fill flow cells that minimizes required sample volume and ensures complete fluid exchange.