Come and visit my poster at HSN (Poster B12; Fri Nov 14, 12:45–2:30)!
Neuropixels in human hippocampus (anesthesia). Neurons show strong tracking of the auditory envelope of sound cues. No evidence for sound-evoked spatial reactivation. Come and have a look! Poster attached.
#HSN25
Neuropixels in human hippocampus (anesthesia). Neurons show strong tracking of the auditory envelope of sound cues. No evidence for sound-evoked spatial reactivation. Come and have a look! Poster attached.
#HSN25
November 12, 2025 at 12:57 AM
Come and visit my poster at HSN (Poster B12; Fri Nov 14, 12:45–2:30)!
Neuropixels in human hippocampus (anesthesia). Neurons show strong tracking of the auditory envelope of sound cues. No evidence for sound-evoked spatial reactivation. Come and have a look! Poster attached.
#HSN25
Neuropixels in human hippocampus (anesthesia). Neurons show strong tracking of the auditory envelope of sound cues. No evidence for sound-evoked spatial reactivation. Come and have a look! Poster attached.
#HSN25
Our weekly meeting for the OpenScope Predictive Processing community project is cancelled for tomorrow. We are currently collectling datasets both on the Neuropixels and SLAP2 platform. At our next meeting, we aim to introduce those datasets to allow analysis by the community.
November 11, 2025 at 12:49 AM
Our weekly meeting for the OpenScope Predictive Processing community project is cancelled for tomorrow. We are currently collectling datasets both on the Neuropixels and SLAP2 platform. At our next meeting, we aim to introduce those datasets to allow analysis by the community.
All talks of the 2025 UCL #Neuropixels course are now available: www.youtube.com/playlist?lis...
For more information on the course see the website: www.ucl.ac.uk/neuropixels/...
And for those at #SfN, come say hi at the #Neuropixels booth (Number 3731) or at my Poster 👋.
Happy Neuropixeling!
For more information on the course see the website: www.ucl.ac.uk/neuropixels/...
And for those at #SfN, come say hi at the #Neuropixels booth (Number 3731) or at my Poster 👋.
Happy Neuropixeling!
2025 UCL Neuropixels Course - YouTube
Lectures at the 2025 UCL Neuropixels course (https://www.ucl.ac.uk/neuropixels/training/2025-neuropixels-course)
www.youtube.com
November 10, 2025 at 1:48 PM
All talks of the 2025 UCL #Neuropixels course are now available: www.youtube.com/playlist?lis...
For more information on the course see the website: www.ucl.ac.uk/neuropixels/...
And for those at #SfN, come say hi at the #Neuropixels booth (Number 3731) or at my Poster 👋.
Happy Neuropixeling!
For more information on the course see the website: www.ucl.ac.uk/neuropixels/...
And for those at #SfN, come say hi at the #Neuropixels booth (Number 3731) or at my Poster 👋.
Happy Neuropixeling!
New preprint:
Neural manifolds that orchestrate walking and stopping
Here we develop a new theory for neural generation of walking and how it can stop- Next we test the theory using Neuropixels probes in the lumber spinal cord of freely moving rats. See more:
www.biorxiv.org/content/10.1...
Neural manifolds that orchestrate walking and stopping
Here we develop a new theory for neural generation of walking and how it can stop- Next we test the theory using Neuropixels probes in the lumber spinal cord of freely moving rats. See more:
www.biorxiv.org/content/10.1...
November 9, 2025 at 9:33 PM
New preprint:
Neural manifolds that orchestrate walking and stopping
Here we develop a new theory for neural generation of walking and how it can stop- Next we test the theory using Neuropixels probes in the lumber spinal cord of freely moving rats. See more:
www.biorxiv.org/content/10.1...
Neural manifolds that orchestrate walking and stopping
Here we develop a new theory for neural generation of walking and how it can stop- Next we test the theory using Neuropixels probes in the lumber spinal cord of freely moving rats. See more:
www.biorxiv.org/content/10.1...
I’m well aware of single-neuron recordings in human patients; but to date, they’ve been very restricted in terms of where you can record and under what conditions (and data quality, although Neuropixels and other electrodes could indeed change that dramatically)...
November 3, 2025 at 11:44 AM
I’m well aware of single-neuron recordings in human patients; but to date, they’ve been very restricted in terms of where you can record and under what conditions (and data quality, although Neuropixels and other electrodes could indeed change that dramatically)...
You can record single units, including using neuropixels, from patients. And you can collect causal evidence using electric stimulation, pharmacology or non invasive stimulation such as TUS. I love monkey data, but the human toolkit is much wider than "simply fmri"
November 3, 2025 at 11:15 AM
You can record single units, including using neuropixels, from patients. And you can collect causal evidence using electric stimulation, pharmacology or non invasive stimulation such as TUS. I love monkey data, but the human toolkit is much wider than "simply fmri"
✨ Planned features include:
- A user-friendly Python interface to automate processing of Bonsai outputs for seamless integration with analysis tools (e.g. movement, pose-tracking, etc.)
- Alignment tools for synchronising pose-tracking, Bonsai, and Neuropixels data using common xarray structures
- A user-friendly Python interface to automate processing of Bonsai outputs for seamless integration with analysis tools (e.g. movement, pose-tracking, etc.)
- Alignment tools for synchronising pose-tracking, Bonsai, and Neuropixels data using common xarray structures
October 29, 2025 at 5:06 PM
✨ Planned features include:
- A user-friendly Python interface to automate processing of Bonsai outputs for seamless integration with analysis tools (e.g. movement, pose-tracking, etc.)
- Alignment tools for synchronising pose-tracking, Bonsai, and Neuropixels data using common xarray structures
- A user-friendly Python interface to automate processing of Bonsai outputs for seamless integration with analysis tools (e.g. movement, pose-tracking, etc.)
- Alignment tools for synchronising pose-tracking, Bonsai, and Neuropixels data using common xarray structures
Release her! Don't be an ananasshole!🍍
October 27, 2025 at 8:00 PM
Release her! Don't be an ananasshole!🍍
With 2 weeks to go until our #webinar looking at co-produced methods for monitoring of sleep, we wanted to introduce our two speakers. Read their bios in the graphics below👇 Book our webinar now: zoom.us/webinar/regi...
October 22, 2025 at 10:41 AM
With 2 weeks to go until our #webinar looking at co-produced methods for monitoring of sleep, we wanted to introduce our two speakers. Read their bios in the graphics below👇 Book our webinar now: zoom.us/webinar/regi...
MC looks like a jumble @ neuron levels but seems coordinated when looking @ populations. But population studies mostly lump neurons all together w/out looking for spatial structure. Ryan used Neuropixels to widely sample neural populations across frontal motor cortices to quantify spatial structure.
October 20, 2025 at 6:54 PM
MC looks like a jumble @ neuron levels but seems coordinated when looking @ populations. But population studies mostly lump neurons all together w/out looking for spatial structure. Ryan used Neuropixels to widely sample neural populations across frontal motor cortices to quantify spatial structure.
CU Anschutz is the first site with FDA authorization to use Neuropixels technology during brain surgery to study executive function and unlock insights into Parkinson’s disease. Read more about the study: https://bit.ly/4o4iX2R
CU Anschutz Announces Study Using Groundbreaking Neuropixels Technology to Unlock New Insights Into Parkinson’s Disease
CU Anschutz doctors employed the first FDA-approved use of Neuropixels technology to study the impact of Parkinson's disease on patient executive function.
news.cuanschutz.edu
October 17, 2025 at 7:15 PM
CU Anschutz is the first site with FDA authorization to use Neuropixels technology during brain surgery to study executive function and unlock insights into Parkinson’s disease. Read more about the study: https://bit.ly/4o4iX2R
A brain-wide map of neural activity recorded in the context of decision making. Revealed by 621,733 neurons recorded with 699 Neuropixels probes across 139 mice in 12 laboratories. 🤯
www.nature.com/articles/s41...
www.nature.com/articles/s41...
A brain-wide map of neural activity during complex behaviour - Nature
The International Brain Laboratory presents a brain-wide electrophysiological map obtained from pooling data from 12 laboratories that performed the same standardized perceptual decision-making task i...
www.nature.com
October 15, 2025 at 7:34 PM
A brain-wide map of neural activity recorded in the context of decision making. Revealed by 621,733 neurons recorded with 699 Neuropixels probes across 139 mice in 12 laboratories. 🤯
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Had a great visit to the center for Mind, Brain, Computation and Technology @ Stanford yesterday! I was excited to talk about brewing ideas in the lab on neural representations at neuron & population scales. Plus new data mapping motor cortex w/ neuropixels - preprint dropping soon, stay tuned! 🍿
October 14, 2025 at 3:29 PM
Had a great visit to the center for Mind, Brain, Computation and Technology @ Stanford yesterday! I was excited to talk about brewing ideas in the lab on neural representations at neuron & population scales. Plus new data mapping motor cortex w/ neuropixels - preprint dropping soon, stay tuned! 🍿
Neuropixels can bend, right?
In honour of spooky month, share a 4 word horror story that only someone in your profession would understand.
rm -rf ~/
rm -rf ~/
"The chancellor approved it"
October 12, 2025 at 5:12 PM
Neuropixels can bend, right?
Calcium imaging / Patch Clamp / Neuropixels
Associate Professor / Full Professor / Assistant Professor
October 8, 2025 at 11:03 AM
Calcium imaging / Patch Clamp / Neuropixels
Ultra-high-density Neuropixels probes improve detection and identification in neuronal recordings: www.cell.com/neuron/fullt...
6 μm site-to-site spacing.
Cortical cell types could be discriminated from one another with ∼80% accuracy and from other neurons with ∼85% accuracy.
6 μm site-to-site spacing.
Cortical cell types could be discriminated from one another with ∼80% accuracy and from other neurons with ∼85% accuracy.
October 5, 2025 at 8:15 PM
Ultra-high-density Neuropixels probes improve detection and identification in neuronal recordings: www.cell.com/neuron/fullt...
6 μm site-to-site spacing.
Cortical cell types could be discriminated from one another with ∼80% accuracy and from other neurons with ∼85% accuracy.
6 μm site-to-site spacing.
Cortical cell types could be discriminated from one another with ∼80% accuracy and from other neurons with ∼85% accuracy.
Neuropixels Ultra, an ultra-high density brain probe, enables detailed recording and classification of individual brain cell types and their electrical patterns across multiple species during behavior. doi.org/g95rwr
High-density brain probe reveals distinctive electrical patterns of cell types during behavior
Trying to document how single brain cells participate in networks that govern behavior is a daunting task. Brain probes called Neuropixels, which feature high-density silicon arrays, have enabled scientists to collect electrophysiological data of this nature from a variety of animals.
medicalxpress.com
October 3, 2025 at 3:27 PM
Neuropixels Ultra, an ultra-high density brain probe, enables detailed recording and classification of individual brain cell types and their electrical patterns across multiple species during behavior. doi.org/g95rwr
Brain probe Neuropixels Ultra powerfully records neural circuits during behavior. International collaboration to design and test probe coordinated by Nick Steinmetz lab @uwmedicine.bsky.social. Also @alleninstitute.org and others.
Probe powerfully records neural circuits during behavior - UW Medicine | Newsroom
newsroom.uw.edu
October 2, 2025 at 11:53 PM
Brain probe Neuropixels Ultra powerfully records neural circuits during behavior. International collaboration to design and test probe coordinated by Nick Steinmetz lab @uwmedicine.bsky.social. Also @alleninstitute.org and others.
Lots of exciting clinical PhD projects at Crick - including the opportunity for neurosurgeons to work with us and record electrical activity in patients with neuropixels probes. Please share widely!
We're looking for clinicians who are passionate about research to join our 3-year fully funded clinical PhD programme. 🔬🩺
Apply by 14 November 2025. 👇
www.crick.ac.uk/careers-stud...
Apply by 14 November 2025. 👇
www.crick.ac.uk/careers-stud...
Doctoral clinical fellows
The Crick's clinical PhD programme.
www.crick.ac.uk
October 1, 2025 at 10:08 AM
Lots of exciting clinical PhD projects at Crick - including the opportunity for neurosurgeons to work with us and record electrical activity in patients with neuropixels probes. Please share widely!
Neuropixels Ultra!
By @steinmetzneuro.bsky.social, who led a big collaboration
www.sciencedirect.com/science/arti...
By @steinmetzneuro.bsky.social, who led a big collaboration
www.sciencedirect.com/science/arti...
Ultra-high-density Neuropixels probes improve detection and identification in neuronal recordings
To understand the neural basis of behavior, it is essential to sensitively and accurately measure neural activity at single-neuron and single-spike re…
www.sciencedirect.com
September 30, 2025 at 3:11 PM
Neuropixels Ultra!
By @steinmetzneuro.bsky.social, who led a big collaboration
www.sciencedirect.com/science/arti...
By @steinmetzneuro.bsky.social, who led a big collaboration
www.sciencedirect.com/science/arti...
CU Anschutz Uses Neuropixels Technology to Explore Parkinson's Disease Insights#USA#Denver#Parkinson's_Disease#CU_Anschutz#Neuropixels
CU Anschutz Uses Neuropixels Technology to Explore Parkinson's Disease Insights
The University of Colorado Anschutz employs the innovative Neuropixels technology to advance understanding of Parkinson's disease, focusing on executive function disruption.
third-news.com
September 30, 2025 at 10:35 AM
CU Anschutz Uses Neuropixels Technology to Explore Parkinson's Disease Insights#USA#Denver#Parkinson's_Disease#CU_Anschutz#Neuropixels
Les chercheurs ont utilisé 699 sondes Neuropixels capables d'enregistrer des milliers de neurones simultanément. Toutes les données sont ouvertes pour que d'autres scientifiques puissent les analyser.
www.internationalbra...
8/10
www.internationalbra...
8/10
The Brain-Wide Map — International Brain Laboratory
Explore the IBL Brain‑Wide Map: recordings from 621,733 neurons across 279
brain areas. Interactive dataset, download access & code for neural
activity research.
www.internationalbrainlab.com
September 30, 2025 at 10:21 AM
Les chercheurs ont utilisé 699 sondes Neuropixels capables d'enregistrer des milliers de neurones simultanément. Toutes les données sont ouvertes pour que d'autres scientifiques puissent les analyser.
www.internationalbra...
8/10
www.internationalbra...
8/10
Next week, we will host 2 meetings as part of the OpenScope predictive processing community project.
On Tuesday 09/30, 9AM PST, we will finalize our Neuropixels pilot design and provide updates on the review journal submission.
allenneuraldynamics.github.io/openscope-co...
On Tuesday 09/30, 9AM PST, we will finalize our Neuropixels pilot design and provide updates on the review journal submission.
allenneuraldynamics.github.io/openscope-co...
2025-09-30 - OpenScope Community Predictive Processing
allenneuraldynamics.github.io
September 26, 2025 at 6:30 PM
Next week, we will host 2 meetings as part of the OpenScope predictive processing community project.
On Tuesday 09/30, 9AM PST, we will finalize our Neuropixels pilot design and provide updates on the review journal submission.
allenneuraldynamics.github.io/openscope-co...
On Tuesday 09/30, 9AM PST, we will finalize our Neuropixels pilot design and provide updates on the review journal submission.
allenneuraldynamics.github.io/openscope-co...
(6/7) 🧪 In real electrophysiology data (Neuropixels in mice), MR-LFADS predicts brain-wide effects of circuit perturbations (ALM photoinhibition) that it had never seen during training!
September 25, 2025 at 10:26 PM
(6/7) 🧪 In real electrophysiology data (Neuropixels in mice), MR-LFADS predicts brain-wide effects of circuit perturbations (ALM photoinhibition) that it had never seen during training!
So happy to release this to the world!! A big one that's been cooking for years.
If you like #Memory #GridCells #PlaceCells #Theory #Attractors #Neuropixels or just anything exciting in #Neuroscience, this is a must read 👇
If you like #Memory #GridCells #PlaceCells #Theory #Attractors #Neuropixels or just anything exciting in #Neuroscience, this is a must read 👇
1/5 How does the brain turn the low-dimensional, universal grid cell metric into the rich, diverse codes needed for memory in hippocampal place cells? 🧵
Preprint link 👇
www.biorxiv.org/content/10.1...
Preprint link 👇
www.biorxiv.org/content/10.1...
Functional independence of entorhinal grid cell modules enables remapping in hippocampal place cells
A systems-level understanding of cortical computation requires insight into how neural codes are transformed across distinct brain circuits. In the mammalian cortex, one of the few systems where such ...
www.biorxiv.org
September 25, 2025 at 4:26 AM
So happy to release this to the world!! A big one that's been cooking for years.
If you like #Memory #GridCells #PlaceCells #Theory #Attractors #Neuropixels or just anything exciting in #Neuroscience, this is a must read 👇
If you like #Memory #GridCells #PlaceCells #Theory #Attractors #Neuropixels or just anything exciting in #Neuroscience, this is a must read 👇