#NatureCancer
Excited to share our latest work in @NatureCancer to get a better understanding why relapsed T-ALL is so deadly and potential target strategies, led by Jason Xu and @changya1 with members of David Teachey, @junjyang, @CMullighan and many great colleagues.

twtr.to/foS9o
March 18, 2025 at 1:08 AM
Crowdsourcing a crisis response for COVID-19 in oncology [Apr 21, 2020] @ADesaiMD @hemoncwarner @NicoleKuderer @mtmdphd @corrie_painter @gary_lyman @GlopesMd @NatureCancer ow.ly/wuyD30qzDyS #CCC19 #COVID19nCANCER @COVID19nCCC
Crowdsourcing a crisis response for COVID-19 in oncology - Nature Cancer
Crowdsourcing efforts are currently underway to collect and analyze data from patients with cancer who are affected by the COVID-19 pandemic. These community-led initiatives will fill key knowledge ga...
ow.ly
February 14, 2025 at 1:32 PM
⭐️New Article ONLINE at NatureCancer !

Concurrent inhibition of tumor growth and metastasis by a lipidated nanophotosensitizer tracing and disabling tumor extracellular vesicles

✏️By Xiaorui Wang and colleagues

🔗 www.nature.com/articles/s43...
Concurrent inhibition of tumor growth and metastasis by a lipidated nanophotosensitizer tracing and disabling tumor extracellular vesicles - Nature Cancer
Wang and colleagues describe the design and characterization of lipidated nanophotosensitizers, promoting photodynamic suppression of primary tumor growth and inhibition of metastasis by disabling tum...
www.nature.com
June 30, 2025 at 9:36 AM
Transmissible cancer in marine mussels. On depth study this week on the cover of @NatureCancer
Nature Cancer - Transmissible marine cancer evolution
Transmissible leukemia-like cancer in the marine species Cerastoderma edule and Mya arenaria is characterized by long-term tolerance as well as genomic...
www.nature.com
November 28, 2023 at 8:26 AM
How explainable, multimodal #AI of real world cancer patient data has the potential to increase accuracy of prognosis and optimize treatment
www.nature.com/articles/s43...
@NatureCancer open-access
Decoding pan-cancer treatment outcomes using multimodal real-world data and explainable artificial intelligence - Nature Cancer
Keyl et al. present an explainable artificial intelligence model-based real-world data analysis from over 15,000 patients across 38 cancer types, identified key prognostic marker interactions, and con...
www.nature.com
January 30, 2025 at 4:39 PM
The therapy led to the death of tumor cells at the treated sites and simultaneously activated the adaptive immune system to fight even distant metastases. The results published in the top journal #NatureCancer could improve the treatment of superficial tumors such as melanoma and breast cancer.
January 23, 2025 at 12:43 PM
I am delighted to share our new study uncovering the role of innate immunity in regulating cell plasticity and reprograming of prostate tumor initiating cells published in
@NatureCancer
. Congrats
@ChenJiang919
and
@yura__song
, the first authors,
www.nature.com/articles/s43...
Innate immunity and the NF-κB pathway control prostate stem cell plasticity, reprogramming and tumor initiation - Nature Cancer
Blanpain and colleagues delineate lineage reprogramming following PTEN deletion in different prostate cancer-originating cells, demonstrating that in basal cells the NF-κB pathway and innate immunity ...
www.nature.com
June 23, 2025 at 1:23 PM
Resource article now online @NatureCancer
'An organoid library unveils subtype-specific IGF-1 dependency via a YAP–AP1 axis in human small cell lung cancer'

✏️By Toshiro Sato & colleagues
📎https://www.nature.com/articles/s43018-025-00945-y?utm_source=bluesky&utm_medium=social&utm_campaign=natcancer
May 6, 2025 at 12:20 PM
Resource article published now @NatureCancer

'Spatiotemporal analyses of the pan-cancer single-cell landscape reveal widespread profibrotic ecotypes associated with tumor immunity'

✒️By Qiu Wu, Chenfei Wang and colleagues

🔗 www.nature.com/articles/s43...
Spatiotemporal analyses of the pan-cancer single-cell landscape reveal widespread profibrotic ecotypes associated with tumor immunity - Nature Cancer
Han et al. present TabulaTIME, a multicancer scRNA-seq resource, and report enrichment of extracellular matrix-related CTHRC1+ cancer-associated fibroblasts in proximity to SLPI+ macrophages, creating...
www.nature.com
August 29, 2025 at 9:11 AM
Crowdsourcing a crisis response for COVID-19 in oncology [Apr 21, 2020] @ADesaiMD @hemoncwarner @NicoleKuderer @mtmdphd @corrie_painter @gary_lyman @GlopesMd @NatureCancer ow.ly/wuyD30qzDyS #CCC19 #COVID19nCANCER @COVID19nCCC
Crowdsourcing a crisis response for COVID-19 in oncology - Nature Cancer
Crowdsourcing efforts are currently underway to collect and analyze data from patients with cancer who are affected by the COVID-19 pandemic. These community-led initiatives will fill key knowledge ga...
ow.ly
November 19, 2024 at 1:10 PM
Multiple #myeloma, a form of bone marrow cancer, can progress very aggressively. #mdcBerlin researchers now show for the first time at the #proteogenomic level how previously incurable forms can be recognized early and thus treated. 👇 #NatureCancer #ChariteBerlin #BIH
Multiple myeloma: Early detection of aggressive tumors
Berlin researchers and their partners describe how aggressive variants of multiple myeloma can be detected early. Their comprehensive study in “Nature Cancer” shows how changes in genetic material aff...
www.mdc-berlin.de
June 28, 2024 at 12:31 PM
New #NatureCancer paper: Skeletal muscle endothelial dysfunction through the activin A–PGC1α axis drives progression of cancer cachexia. #Myoblue tinyurl.com/yhjx4sjt
Skeletal muscle endothelial dysfunction through the activin A–PGC1α axis drives progression of cancer cachexia - Nature Cancer
Using multiple in vivo mouse models, Rehman and colleagues report that tumor-induced impairments in the muscle vasculature mediated by circulating activin A contribute to cachexia development during c...
tinyurl.com
May 26, 2025 at 4:46 PM
🎂Our 5-YEAR ANNIVERSARY Issue is now ONLINE!
@NatureCancer

Find it here:
www.nature.com/natcancer/vo...

Features:
⭐️Reviews and opinion pieces
⭐️Research articles
on key developments in #cancerresearch and #oncology
January 30, 2025 at 4:31 PM
Metastatic patterns stratify patients with pancreatic cancer ⁦‪@NatureCancer‬⁩

www.nature.com/articles/s43...
Metastatic patterns stratify patients with pancreatic cancer - Nature Cancer
Patients with lung-metastatic pancreatic ductal adenocarcinoma survive longer than those with liver metastases. A study now leverages real-world data to identify distinct molecular and immune profiles...
www.nature.com
February 9, 2025 at 3:27 PM
🚨Today, in #NatureCancer, we show that #CAR-T cells and #CAR-NK cells contain the seeds of their own self-destruction. Disruption of a FAS-L/FAS enhances CAR potency against liquid and solid cancers. rdcu.be/exjEy. @mskcancercenter.bsky.social @parkerici.bsky.social
CAR-engineered lymphocyte persistence is governed by a FAS ligand–FAS autoregulatory circuit
Nature Cancer - Klebanoff and colleagues report that survival and persistence of CAR-T and CAR-NK cells are regulated by a FAS ligand–FAS autoregulatory circuit, showing that disabling FAS...
rdcu.be
July 23, 2025 at 8:39 PM
Great collab at Hagey Lab between @delittoD and Dr. Michael Longaker www.nature.com/articles/s43...

@StanfordPlastic @StanfordGenSurg @LongakerLab @NatureCancer
Cancer-derived mitochondria fuel fibroblasts to become pro-tumorigenic - Nature Cancer
Cancer-associated fibroblasts represent a functionally diverse and heterogeneous entity within the solid tumor microenvironment. Mitochondrial transfer from cancer cells to fibroblasts is now shown…
www.nature.com
August 30, 2025 at 2:22 AM
Cutting-edge study from @timwartewig et al. published in @NatureCancer, delves into histone modifications and epigenetic regulation of PD-1 in mice using LC-MS/MS, ChIP-seq, and CRISPR-Cas9, offering insights for immunology & #cancer #research. For more; bit.ly/IO-Wartewig-...
#proteomics #massspec
November 27, 2023 at 5:10 AM
Ongoing replication stress tolerance and clonal T cell responses distinguish liver and lung recurrence and outcomes in pancreatic cancer ⁦‪@NatureCancer‬⁩

www.nature.com/articles/s43...
Ongoing replication stress tolerance and clonal T cell responses distinguish liver and lung recurrence and outcomes in pancreatic cancer - Nature Cancer
Sears and colleagues found that ongoing replication stress pathways and T cell clonal responses differentiate liver and lung recurrence and are associated with different clinical outcomes in the conte...
www.nature.com
March 2, 2025 at 12:43 PM
Crowdsourcing a crisis response for COVID-19 in oncology [Apr 21, 2020] @ADesaiMD @hemoncwarner @NicoleKuderer @mtmdphd @corrie_painter @gary_lyman @GlopesMd @NatureCancer ow.ly/wuyD30qzDyS #CCC19 #COVID19nCANCER @COVID19nCCC
March 10, 2025 at 5:47 PM
I know I should not be affected by this, but a review just got published citing close to *200* papers on applications of organoids for cancer biology and precision medicine in @NatureCancer and our work was ignored entirely.
So I will be in the corner screaming.
November 27, 2024 at 4:07 AM
Impressive study from the lab of Thomas R. Cox on the development & deployment of a novel anti-fibrotic in pancreatic cancer has just been published (OpenAccess) in @NatureCancer | → nature.com/articles/s4301… ← | @TCox_Lab @GarvanInstitute #extracellularmatrix #ECM #cancer
September 26, 2023 at 7:28 AM
Translation strikes again! A beautiful and important work in @NatureCancer on unveiling a new functional link between the translation factor eIF5B and cancer immune evasion! Congrats to @shruthy_suresh and @ODonnellLab_K!

nature.com/articles/s4301…
eIF5B drives integrated stress response-dependent translation of PD-L1 in lung cancer
Nature Cancer - O’Donnell and colleagues report that activation of the integrated stress response in non-small cell lung cancer cells by impairing heme production leads to enhanced PD-L1...
www.nature.com
March 24, 2025 at 12:53 AM
An antibody–toxin conjugate targeting the ‘don’t eat me’ signal CD47 linked to the bacterial toxin listeriolysin O for cancer immunotherapy. #NatureCancer

www.nature.com/articles/s43...
An antibody–toxin conjugate targeting CD47 linked to the bacterial toxin listeriolysin O for cancer immunotherapy - Nature Cancer
Schrank et al. report the design and characterization of an antibody–toxin conjugate targeting CD47, promoting anti-tumor immunity in preclinical cancer models.
www.nature.com
February 28, 2025 at 12:15 AM