7/10
Finally, we used chimeric gastruloids derived from a mix of wild-type (WT) and MSGN1 KO cells. This revealed that MSGN1 KO cells can form spinal cord in the presence of WT cells.
This indicates an underlying inter-tissue communication program driven by MSGN1.
Finally, we used chimeric gastruloids derived from a mix of wild-type (WT) and MSGN1 KO cells. This revealed that MSGN1 KO cells can form spinal cord in the presence of WT cells.
This indicates an underlying inter-tissue communication program driven by MSGN1.
March 18, 2025 at 9:38 AM
7/10
Finally, we used chimeric gastruloids derived from a mix of wild-type (WT) and MSGN1 KO cells. This revealed that MSGN1 KO cells can form spinal cord in the presence of WT cells.
This indicates an underlying inter-tissue communication program driven by MSGN1.
Finally, we used chimeric gastruloids derived from a mix of wild-type (WT) and MSGN1 KO cells. This revealed that MSGN1 KO cells can form spinal cord in the presence of WT cells.
This indicates an underlying inter-tissue communication program driven by MSGN1.
6/10
Surprisingly, MSGN1 KO not only impaired mesoderm development, as anticipated, but also negatively affected spinal cord development. This reveals an inter-tissue role of MSGN1 that was previously unknown.
Surprisingly, MSGN1 KO not only impaired mesoderm development, as anticipated, but also negatively affected spinal cord development. This reveals an inter-tissue role of MSGN1 that was previously unknown.
March 18, 2025 at 9:36 AM
6/10
Surprisingly, MSGN1 KO not only impaired mesoderm development, as anticipated, but also negatively affected spinal cord development. This reveals an inter-tissue role of MSGN1 that was previously unknown.
Surprisingly, MSGN1 KO not only impaired mesoderm development, as anticipated, but also negatively affected spinal cord development. This reveals an inter-tissue role of MSGN1 that was previously unknown.
5/10
We were particularly struck by MSGN1 and CDX2 as potential drivers of the early decision from neuromesodermal progenitors (NMPs) to mesoderm and spinal cord, respectively.
We were particularly struck by MSGN1 and CDX2 as potential drivers of the early decision from neuromesodermal progenitors (NMPs) to mesoderm and spinal cord, respectively.
March 18, 2025 at 9:34 AM
5/10
We were particularly struck by MSGN1 and CDX2 as potential drivers of the early decision from neuromesodermal progenitors (NMPs) to mesoderm and spinal cord, respectively.
We were particularly struck by MSGN1 and CDX2 as potential drivers of the early decision from neuromesodermal progenitors (NMPs) to mesoderm and spinal cord, respectively.
December 28, 2024 at 10:47 PM
Happy #fluorescencefriday!
Oh gosh I'm tired (description on the ALT)
Oh gosh I'm tired (description on the ALT)
December 13, 2024 at 4:26 PM
Happy #fluorescencefriday!
Oh gosh I'm tired (description on the ALT)
Oh gosh I'm tired (description on the ALT)
November 23, 2024 at 4:27 AM