#LatestPublication
Varsha from Dr. Raj Ladher’s lab finds that early inner ear fusion needs a hybrid EMT, where Grhl2/Sp8 remodel junctions to balance new contacts & tissue integrity.
This stunning image of an otocyst, taken by Varsha, featured on the cover!
bit.ly/4omQgOL
@earlab.bsky.social
Varsha from Dr. Raj Ladher’s lab finds that early inner ear fusion needs a hybrid EMT, where Grhl2/Sp8 remodel junctions to balance new contacts & tissue integrity.
This stunning image of an otocyst, taken by Varsha, featured on the cover!
bit.ly/4omQgOL
@earlab.bsky.social
October 16, 2025 at 11:56 AM
#LatestPublication
Varsha from Dr. Raj Ladher’s lab finds that early inner ear fusion needs a hybrid EMT, where Grhl2/Sp8 remodel junctions to balance new contacts & tissue integrity.
This stunning image of an otocyst, taken by Varsha, featured on the cover!
bit.ly/4omQgOL
@earlab.bsky.social
Varsha from Dr. Raj Ladher’s lab finds that early inner ear fusion needs a hybrid EMT, where Grhl2/Sp8 remodel junctions to balance new contacts & tissue integrity.
This stunning image of an otocyst, taken by Varsha, featured on the cover!
bit.ly/4omQgOL
@earlab.bsky.social
#LatestPublication
Dr @shaonchakrabarti.bsky.social & team combine single-cell & population level measurements to show that most of the information of cell fate is already pre-programmed in the cancer cells, well before the addition of the drug.
tinyurl.com/mrydz4rf
🎉Congratulations, team!
Dr @shaonchakrabarti.bsky.social & team combine single-cell & population level measurements to show that most of the information of cell fate is already pre-programmed in the cancer cells, well before the addition of the drug.
tinyurl.com/mrydz4rf
🎉Congratulations, team!
Inheritable cell-states shape drug-persister correlations and population dynamics in cancer cells
Author summary It is now well understood that evasion of drug effects on short time-scales by cancer cells (drug tolerant persisters or DTPs) originates from cell fate outcomes driven by non-genetic h...
tinyurl.com
October 14, 2025 at 12:05 PM
#LatestPublication
Dr @shaonchakrabarti.bsky.social & team combine single-cell & population level measurements to show that most of the information of cell fate is already pre-programmed in the cancer cells, well before the addition of the drug.
tinyurl.com/mrydz4rf
🎉Congratulations, team!
Dr @shaonchakrabarti.bsky.social & team combine single-cell & population level measurements to show that most of the information of cell fate is already pre-programmed in the cancer cells, well before the addition of the drug.
tinyurl.com/mrydz4rf
🎉Congratulations, team!
#LatestPublication
@harshithcy.bsky.social from @shivaprasadpv.bsky.social's lab identified the role of transcription factor OsWRKY53 that dictates wound responses in rice. It fine-tunes wound responses by turning on defence-related genes while turning down growth-related ones.
bit.ly/4ojkJgT
@harshithcy.bsky.social from @shivaprasadpv.bsky.social's lab identified the role of transcription factor OsWRKY53 that dictates wound responses in rice. It fine-tunes wound responses by turning on defence-related genes while turning down growth-related ones.
bit.ly/4ojkJgT
OsWRKY53 dictates wound responses in rice through fine‐tuning crosstalk between PEP and PSK‐mediated signalling
Wound response in plants is a dynamic event involving a significant transcriptional reprogramming. Monocots display distinct phenotypes upon wounding, and the molecular mechanism involved in early si...
bit.ly
October 14, 2025 at 12:41 PM
#LatestPublication
@harshithcy.bsky.social from @shivaprasadpv.bsky.social's lab identified the role of transcription factor OsWRKY53 that dictates wound responses in rice. It fine-tunes wound responses by turning on defence-related genes while turning down growth-related ones.
bit.ly/4ojkJgT
@harshithcy.bsky.social from @shivaprasadpv.bsky.social's lab identified the role of transcription factor OsWRKY53 that dictates wound responses in rice. It fine-tunes wound responses by turning on defence-related genes while turning down growth-related ones.
bit.ly/4ojkJgT
#LatestPublication
In a latest study published in PLOS Genetics, Ramankaushik and team from Dr Raj Ladher's lab describe a new role for protocadherin-15 in patterning the hair cell.
🎉Congratulations to the team!
journals.plos.org/plosgenetics...
In a latest study published in PLOS Genetics, Ramankaushik and team from Dr Raj Ladher's lab describe a new role for protocadherin-15 in patterning the hair cell.
🎉Congratulations to the team!
journals.plos.org/plosgenetics...
Role of Pcdh15 in the development of intrinsic polarity of inner ear hair cells
Author summary Hearing, like other sensory modalities, is essential for animals to perceive and interact with their environment. The cochlea, the auditory sensory organ, develops under tight genetic r...
journals.plos.org
August 19, 2025 at 11:07 AM
#LatestPublication
In a latest study published in PLOS Genetics, Ramankaushik and team from Dr Raj Ladher's lab describe a new role for protocadherin-15 in patterning the hair cell.
🎉Congratulations to the team!
journals.plos.org/plosgenetics...
In a latest study published in PLOS Genetics, Ramankaushik and team from Dr Raj Ladher's lab describe a new role for protocadherin-15 in patterning the hair cell.
🎉Congratulations to the team!
journals.plos.org/plosgenetics...
#LatestPublication
Akshaya Seshadri from Dr @anjbadri.bsky.social's lab uncovered a mechanism of mtDNA clearance following damage, driven by exonuclease activity of the mtDNA replicative polymerase Mip1.
Read here: bit.ly/42FTxRG
@emboreports.org
🎉Congratulations to the team!
Akshaya Seshadri from Dr @anjbadri.bsky.social's lab uncovered a mechanism of mtDNA clearance following damage, driven by exonuclease activity of the mtDNA replicative polymerase Mip1.
Read here: bit.ly/42FTxRG
@emboreports.org
🎉Congratulations to the team!
February 4, 2025 at 9:59 AM
#LatestPublication
Akshaya Seshadri from Dr @anjbadri.bsky.social's lab uncovered a mechanism of mtDNA clearance following damage, driven by exonuclease activity of the mtDNA replicative polymerase Mip1.
Read here: bit.ly/42FTxRG
@emboreports.org
🎉Congratulations to the team!
Akshaya Seshadri from Dr @anjbadri.bsky.social's lab uncovered a mechanism of mtDNA clearance following damage, driven by exonuclease activity of the mtDNA replicative polymerase Mip1.
Read here: bit.ly/42FTxRG
@emboreports.org
🎉Congratulations to the team!
#LatestPublication
Harini Krishnan & team from Profs @rpadinjat.bsky.social's & R. Sowdhamini's lab found that genes encoding PIP4K, a key enzyme that controls the levels of PIP3, are found exclusively in metazoans.
Read here: bit.ly/3UdSAL3
🎉Congratulations to the team!
@biologists.bsky.social
Harini Krishnan & team from Profs @rpadinjat.bsky.social's & R. Sowdhamini's lab found that genes encoding PIP4K, a key enzyme that controls the levels of PIP3, are found exclusively in metazoans.
Read here: bit.ly/3UdSAL3
🎉Congratulations to the team!
@biologists.bsky.social
Conserved biochemical activity and function of phosphatidylinositol 5-phosphate 4-kinase regulates growth and development
Summary: Lipid kinase from Porifera shows conserved biochemical activity and function with metazoans in the context of insulin receptor mediated growth and development.
bit.ly
July 16, 2025 at 5:51 AM
#LatestPublication
Harini Krishnan & team from Profs @rpadinjat.bsky.social's & R. Sowdhamini's lab found that genes encoding PIP4K, a key enzyme that controls the levels of PIP3, are found exclusively in metazoans.
Read here: bit.ly/3UdSAL3
🎉Congratulations to the team!
@biologists.bsky.social
Harini Krishnan & team from Profs @rpadinjat.bsky.social's & R. Sowdhamini's lab found that genes encoding PIP4K, a key enzyme that controls the levels of PIP3, are found exclusively in metazoans.
Read here: bit.ly/3UdSAL3
🎉Congratulations to the team!
@biologists.bsky.social
#LatestPublication in @natcomms.nature.com by
Dr Raj Ladher & team show that fine-tuned junctional mechanics are vital for aligning polarity in chicken cochlea.
🎉Congratulations to the team!
@prakash-patterns.bsky.social @earlab.bsky.social
Read here: www.nature.com/articles/s41...
Dr Raj Ladher & team show that fine-tuned junctional mechanics are vital for aligning polarity in chicken cochlea.
🎉Congratulations to the team!
@prakash-patterns.bsky.social @earlab.bsky.social
Read here: www.nature.com/articles/s41...
Junctional force patterning drives both positional order and planar polarity in the auditory epithelia - Nature Communications
Sound is sensed in the cochlea through a precisely organised epithelium. Prakash and colleagues show cellular organisation results from differences in junction contractility, finding mechanics is suff...
www.nature.com
April 30, 2025 at 6:22 AM
#LatestPublication in @natcomms.nature.com by
Dr Raj Ladher & team show that fine-tuned junctional mechanics are vital for aligning polarity in chicken cochlea.
🎉Congratulations to the team!
@prakash-patterns.bsky.social @earlab.bsky.social
Read here: www.nature.com/articles/s41...
Dr Raj Ladher & team show that fine-tuned junctional mechanics are vital for aligning polarity in chicken cochlea.
🎉Congratulations to the team!
@prakash-patterns.bsky.social @earlab.bsky.social
Read here: www.nature.com/articles/s41...
#LatestPublication
Sreepadmanabh & team from Dr @tapomoy89.bsky.social lab, in collab with Prof Ramray Bhat identify distinct chemical regulators of ovarian cancer spheroids.
🔗https://t.co/PTQPMkISNT
Congratulations to the team!🎉
Sreepadmanabh & team from Dr @tapomoy89.bsky.social lab, in collab with Prof Ramray Bhat identify distinct chemical regulators of ovarian cancer spheroids.
🔗https://t.co/PTQPMkISNT
Congratulations to the team!🎉
How do environmental cues reprogram cells and influence multicellular organization? Out today in Small, our collaboration with Prof. Ramray Bhat, led by Sreepadmanabh, identifies distinct chemical regulators of ovarian cancer spheroids.
Read: doi.org/10.1002/smll...
@ncbsbangalore.bsky.social
Read: doi.org/10.1002/smll...
@ncbsbangalore.bsky.social
September 17, 2025 at 6:42 AM
#LatestPublication
Sreepadmanabh & team from Dr @tapomoy89.bsky.social lab, in collab with Prof Ramray Bhat identify distinct chemical regulators of ovarian cancer spheroids.
🔗https://t.co/PTQPMkISNT
Congratulations to the team!🎉
Sreepadmanabh & team from Dr @tapomoy89.bsky.social lab, in collab with Prof Ramray Bhat identify distinct chemical regulators of ovarian cancer spheroids.
🔗https://t.co/PTQPMkISNT
Congratulations to the team!🎉
#LatestPublication
Vrinda & team from Dr Deepa Agashe's lab tracked beetle populations for 5+ years in harsh environments. Findings show how traits of founders influenced the long-term survival of their descendants.
🔗 bit.ly/42hsviC
@deepaagashe.bsky.social
🧵Check out the thread to know more!👇
Vrinda & team from Dr Deepa Agashe's lab tracked beetle populations for 5+ years in harsh environments. Findings show how traits of founders influenced the long-term survival of their descendants.
🔗 bit.ly/42hsviC
@deepaagashe.bsky.social
🧵Check out the thread to know more!👇
September 10, 2025 at 1:08 PM
#LatestPublication
Vrinda & team from Dr Deepa Agashe's lab tracked beetle populations for 5+ years in harsh environments. Findings show how traits of founders influenced the long-term survival of their descendants.
🔗 bit.ly/42hsviC
@deepaagashe.bsky.social
🧵Check out the thread to know more!👇
Vrinda & team from Dr Deepa Agashe's lab tracked beetle populations for 5+ years in harsh environments. Findings show how traits of founders influenced the long-term survival of their descendants.
🔗 bit.ly/42hsviC
@deepaagashe.bsky.social
🧵Check out the thread to know more!👇
#LatestPublication
Anubhav Prakash and team from Dr Raj Ladher's lab investigate the interactions that determine the shape and pattern of the mammalian cochlea.👂
Read here: journals.plos.org/plosbiology/...
🎉Congratulations to the team!
@earlab.bsky.social @plosbiology.org
Anubhav Prakash and team from Dr Raj Ladher's lab investigate the interactions that determine the shape and pattern of the mammalian cochlea.👂
Read here: journals.plos.org/plosbiology/...
🎉Congratulations to the team!
@earlab.bsky.social @plosbiology.org
Coupling between spatial compartments integrates morphogenetic patterning in the organ of Corti
The organ of Corti (OC) in the mammalian cochlea is formed by a sensory domain that, together with surrounding non-sensory domains, undergo cellular rearrangements to form a spiral shape. This study s...
journals.plos.org
September 10, 2025 at 11:10 AM
#LatestPublication
Anubhav Prakash and team from Dr Raj Ladher's lab investigate the interactions that determine the shape and pattern of the mammalian cochlea.👂
Read here: journals.plos.org/plosbiology/...
🎉Congratulations to the team!
@earlab.bsky.social @plosbiology.org
Anubhav Prakash and team from Dr Raj Ladher's lab investigate the interactions that determine the shape and pattern of the mammalian cochlea.👂
Read here: journals.plos.org/plosbiology/...
🎉Congratulations to the team!
@earlab.bsky.social @plosbiology.org