#ImmuneMemory
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Get vaccinated!

"So 10 to 20 percent of people infected with #Measles have the #ImmuneMemory of other infections or vaccinations wiped out, Elledge says. That may leave them vulnerable to illnesses in the future even if they were previously infected or vaccinated against bacteria and viruses."
March 16, 2025 at 7:25 AM
icis-stephanie.bsky.social
Innate immune memory is wild 🧠
Alexander Lercher from Rockefeller dives into how cells remember past infections and prep for future ones. Type I interferon doing way more than just fighting viruses!
Full interview: buff.ly/5TKEJ9o
#CytokineSociety #ImmuneMemory #TypeIInterferon #CellsHaveMemoriesToo
Member Highlight: Alexander Lercher on Innate Immune Memory and Real-World Microbe Responses - Biweekly newsletter of the International Cytokine & Interferon Society
My name is Alexander Lercher, and I am currently a Postdoc in the lab of Charlie Rice at Rockefeller University in New York, and I am particularly excited about studying immune responses in the context...
signals.cytokinesociety.org
October 10, 2025 at 7:04 PM
4040rec.bsky.social
#drugdevelopment #Oncology #FosunPharma #TEV56278 #Teva #monotherapy #combinationtherapy #pembrolizumab #clinicaldatageneration #antiPD1IL2ATTENUKINEtherapy #antitumourTcellactivity #MerckandCo #MSD #enhancedTcellinfiltration #immunememory #preclinicalstudies
pharmatimes.com/news/teva-an...
Teva and Fosun Pharma partner on early-stage oncology drug - PharmaTimes
The candidate is being evaluated as both a monotherapy and in combination pembrolizumab
pharmatimes.com
June 26, 2025 at 9:58 AM
plosbiology.org
How do T stem cell-like memory (TSCM) cells act to maintain long-term #ImmuneMemory? This study reveals that human #TSCM cells comprise two distinct subpopulations with complementary roles; 1. Supporting clonal longevity. 2. Driving expansion & self-renewal @plosbiology.org 🧪 plos.io/4kQi0tL
Models capturing different kinetics and relationships between the cell populations of interest. Model A: Independent homogeneous model. Each population (TN, CD95int, CD95hi) is independent and homogeneous. Model B: Independent heterogeneous model. Each population (TN, CD95int, CD95hi) is independent and allowed (but not constrained) to be heterogeneous. Model C: Forked differentiation model. Upon meeting cognate antigen, TN cells undergo a clonal burst (of size 2k); a fraction (f) differentiate into the CD95int pool with the remainder differentiating into the CD95hi pool. Model D: Linear differentiation model (CD95int first). Upon meeting cognate antigen, TN cells undergo a clonal burst (of size 2k) and differentiate into the CD95int pool which subsequently differentiate into the CD95hi pool. Model E: Linear differentiation model (CD95hi first). Upon meeting cognate antigen, TN cells undergo a clonal burst (of size 2k) and differentiate into the CD95hi pool which subsequently differentiate into the CD95int pool. Note for compactness, in the cartoons, CD95int TSCM are designated Tint and CD95hi TSCM are designated Thi. In every model each population was assumed to be of constant size. The models were fitted to the data to identify which model was most consistent with the experimental observations and to quantify the population parameters.
June 23, 2025 at 4:40 PM
newsmedical.bsky.social
Long COVID patients maintain robust immune memory two years after infection 🔬💪🦠 www.news-medical.net/news/2024091... #LongCOVID #Immunology #SARSCoV2 #Tcells #Bcells #COVID19 #ImmuneMemory #Vaccination #Research #Health
Long COVID patients maintain robust immune memory two years after infection
Researchers discovered that SARS-CoV-2-specific T and B cells in long COVID patients are maintained for two years, similar to fully recovered individuals, offering insights into long-term immunity.
www.news-medical.net
September 18, 2024 at 3:55 AM
castltrastondrs.bsky.social
#Medsky🧪#IDsky #Immunosky #publichealth #Immunememory is essential for the effectiveness #Covid19vaccination

🔥 #COVID19 💉induces durable #Bcell responses in exposed & naive humans

🔥Spike+ #Bcells gradually expand toward the recognition of the RBD subdomain
April 1, 2025 at 1:16 PM
plosbiology.org
How do T stem cell-like memory (TSCM) cells act to maintain long-term #ImmuneMemory? This study reveals that human #TSCM cells comprise two distinct subpopulations with complementary roles; 1. Supporting clonal longevity. 2. Driving expansion & self-renewal @plosbiology.org 🧪 plos.io/4kQi0tL
Models capturing different kinetics and relationships between the cell populations of interest. Model A: Independent homogeneous model. Each population (TN, CD95int, CD95hi) is independent and homogeneous. Model B: Independent heterogeneous model. Each population (TN, CD95int, CD95hi) is independent and allowed (but not constrained) to be heterogeneous. Model C: Forked differentiation model. Upon meeting cognate antigen, TN cells undergo a clonal burst (of size 2k); a fraction (f) differentiate into the CD95int pool with the remainder differentiating into the CD95hi pool. Model D: Linear differentiation model (CD95int first). Upon meeting cognate antigen, TN cells undergo a clonal burst (of size 2k) and differentiate into the CD95int pool which subsequently differentiate into the CD95hi pool. Model E: Linear differentiation model (CD95hi first). Upon meeting cognate antigen, TN cells undergo a clonal burst (of size 2k) and differentiate into the CD95hi pool which subsequently differentiate into the CD95int pool. Note for compactness, in the cartoons, CD95int TSCM are designated Tint and CD95hi TSCM are designated Thi. In every model each population was assumed to be of constant size. The models were fitted to the data to identify which model was most consistent with the experimental observations and to quantify the population parameters.
June 23, 2025 at 1:56 PM
orna.bsky.social
#Measles infection *can* kill, but it also does this insidious thing where it makes your immune system forget how to fight other infections — for as long as three years. That’s always a bad thing, but worse in our #pandemic times.

#ImmuneMemory

news.harvard.edu/gazette/stor...
Study suggests how measles depletes body’s immune memory — Harvard Gazette
A new Harvard study shows measles wipes out 11 percent to 73 percent of antibodies against an array of viruses and bacteria, depleting a child’s previous immunity, which underscores the importance of ...
news.harvard.edu
March 8, 2025 at 3:07 PM
drhowardsmith.bsky.social
Same Arm Boosts CoVid Vax Responses: CoVid vaccinations in the same arm boosts your initial protective antibody responses 4.5 fold. #vaccinate #samearm #immunememory #CoVid #shingles #pneumonia
www.instagram.com/drhowardsmit...
Howard G. Smith MD, AM on Instagram: "Same Arm Boosts CoVid Vax Responses Receiving sequential CoVid vaccinations in the same arm boosts your initial protective antibody responses 4.5 fold. Research ...
0 likes, 0 comments - drhowardsmithreports on March 18, 2025: "Same Arm Boosts CoVid Vax Responses Receiving sequential CoVid vaccinations in the same arm boosts your initial protective antibody resp...
www.instagram.com
March 18, 2025 at 8:24 PM
immuknowledgy.bsky.social
NK cells share a universal signature of memory with B and T cells. Come to my presentation at AAI to find out more.

Sunday April 4th 9:30am Room 316C
#AAI2025 #NKcells #ImmuneMemory
April 30, 2025 at 12:23 AM
geekoo.news
Discover how mRNA vaccines do more than fight COVID-19—they reprogram your immune system for lasting defense. #mRNAVaccine #ImmuneMemory #HealthInnovation
mRNA Vaccines Enhance Immune Memory Beyond Expectations
Emerging research reveals that mRNA COVID-19 vaccines induce lasting epigenetic changes in the innate immune system, enhancing the body's preparedness against future infections and showcasing broader immunological benefits than previously recognized.
geekoo.news
March 28, 2025 at 8:02 PM
plosbiology.org
How do T stem cell-like memory (TSCM) cells act to maintain long-term #ImmuneMemory? This study reveals that human #TSCM cells comprise two distinct subpopulations with complementary roles; 1. Supporting clonal longevity. 2. Driving expansion & self-renewal @plosbiology.org 🧪 plos.io/4kQi0tL
Models capturing different kinetics and relationships between the cell populations of interest. Model A: Independent homogeneous model. Each population (TN, CD95int, CD95hi) is independent and homogeneous. Model B: Independent heterogeneous model. Each population (TN, CD95int, CD95hi) is independent and allowed (but not constrained) to be heterogeneous. Model C: Forked differentiation model. Upon meeting cognate antigen, TN cells undergo a clonal burst (of size 2k); a fraction (f) differentiate into the CD95int pool with the remainder differentiating into the CD95hi pool. Model D: Linear differentiation model (CD95int first). Upon meeting cognate antigen, TN cells undergo a clonal burst (of size 2k) and differentiate into the CD95int pool which subsequently differentiate into the CD95hi pool. Model E: Linear differentiation model (CD95hi first). Upon meeting cognate antigen, TN cells undergo a clonal burst (of size 2k) and differentiate into the CD95hi pool which subsequently differentiate into the CD95int pool. Note for compactness, in the cartoons, CD95int TSCM are designated Tint and CD95hi TSCM are designated Thi. In every model each population was assumed to be of constant size. The models were fitted to the data to identify which model was most consistent with the experimental observations and to quantify the population parameters.
June 23, 2025 at 9:33 AM
newsmedical.bsky.social
Upper airway swabs reveal rich, stable immune memory crucial for respiratory defense 🔬🧬🦠 www.news-medical.net/news/2024080... #Immunology #UpperAirway #COVID19 #ImmuneMemory #MucosalImmunity #Research #Virology #InfectionDefense #BCells #TCells @natureportfolio.bsky.social
Upper airway swabs reveal rich, stable immune memory crucial for respiratory defense
Researchers discovered diverse and stable immune cell populations in the upper respiratory tract, highlighting the critical role of mucosal immunity in COVID-19 and other respiratory diseases.
www.news-medical.net
August 2, 2024 at 2:47 AM
loristarfire.bsky.social
#Measles infection *can* kill, but it also does this insidious thing where it makes your immune system forget how to fight other infections — for as long as three years. That’s always a bad thing, but worse in our #pandemic times.

#ImmuneMemory

news.harvard.edu/gazette/stor...
Study suggests how measles depletes body’s immune memory — Harvard Gazette
A new Harvard study shows measles wipes out 11 percent to 73 percent of antibodies against an array of viruses and bacteria, depleting a child’s previous immunity, which underscores the importance of ...
news.harvard.edu
March 8, 2025 at 5:28 PM
benjamingetenet.fr
Study of 2022 compares immune responses across four #COVID-19 #vaccines (Moderna, Pfizer, Janssen, Novavax). mRNA vaccines show stronger antibody levels and cellular immunity, while all promote memory B cells. Highlights mRNA's edge for durability amid evolving variants. #ImmuneMemory
Humoral and cellular immune memory to four COVID-19 vaccines - PubMed
Multiple COVID-19 vaccines, representing diverse vaccine platforms, successfully protect against symptomatic COVID-19 cases and deaths. Head-to-head comparisons of T cell, B cell, and antibody respons...
pubmed.ncbi.nlm.nih.gov
November 23, 2024 at 9:25 AM