Native nucleosomes intrinsically encode genome organization principles. #Nucleosomes #GenomeArchitecture #Nature
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Nucleosomes as blueprints of genome architecture - Nature Reviews Molecular Cell Biology
Nucleosomes — the basic unit of chromatin architecture — have intrinsic biophysical features of large-scale genome organization.
www.nature.com
June 7, 2025 at 4:31 PM
Native nucleosomes intrinsically encode genome organization principles. #Nucleosomes #GenomeArchitecture #Nature
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Igf2/H19 locus as instructive model to study how allele-specific #GenomeArchitecture facilitates enhancer-promoter interaction that dictate tissue-specific #GeneExpression in #SkeletalMuscle doi.org/10.1371/jour... @Marisa_S_B #TranslationalScience
Igf2 adult-specific skeletal muscle enhancer activity revealed in mice with intergenic CTCF boundary deletion
Author summary All mammals have a unique class of genes that are crucial for normal growth, known as “imprinted genes,” where only one gene copy inherited from a parent is active. Imprinted genes are ...
doi.org
September 2, 2025 at 6:22 PM
Igf2/H19 locus as instructive model to study how allele-specific #GenomeArchitecture facilitates enhancer-promoter interaction that dictate tissue-specific #GeneExpression in #SkeletalMuscle doi.org/10.1371/jour... @Marisa_S_B #TranslationalScience
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@akispapantonis.bsky.social presents "Senescent cells co-opt CTCF on nuclear speckles to sustain their splicing program" on May 8, 4PM UK, moderated by @stefanschoenfelder.bsky.social
#GenomeArchitecture #Senescence
@akispapantonis.bsky.social presents "Senescent cells co-opt CTCF on nuclear speckles to sustain their splicing program" on May 8, 4PM UK, moderated by @stefanschoenfelder.bsky.social
#GenomeArchitecture #Senescence
May 1, 2025 at 1:36 PM
📢 Register! us02web.zoom.us/webinar/regi...
@akispapantonis.bsky.social presents "Senescent cells co-opt CTCF on nuclear speckles to sustain their splicing program" on May 8, 4PM UK, moderated by @stefanschoenfelder.bsky.social
#GenomeArchitecture #Senescence
@akispapantonis.bsky.social presents "Senescent cells co-opt CTCF on nuclear speckles to sustain their splicing program" on May 8, 4PM UK, moderated by @stefanschoenfelder.bsky.social
#GenomeArchitecture #Senescence