📅 Feb 2-5: Human Digital Twin - Cardiopulmonary Physiome Workshop Deep dive into multiscale modeling of cardiopulmonary systems and clinical translation of digital twins. Details: www.cardiacphysiome....
#DigitalTwins🧪
3/6

⁉️ Why this matters at all?

A rigorous, multiscale, uncertainty-aware framework to:

🧬 understand disease mechanisms
🧪 discover biomarkers
💊 identify targets & repurpose drugs
🧠 interpret single-cell & spatial omics
🏥 design predictive, preventive & personalized medicine (e.g., #DigitalTwins)

7/

🧪I didn’t get to post about this earlier, but I recently had the honor of giving the opening keynote at IWOMP 2025. I had a great time talking with the MPI and OpenMP community about opportunities to bring HPC advances to health and scale vascular digital twins. #HPC #OpenMP #MPI #DigitalTwins

In this review, Gangwal & Lavecchia examine how AI-powered #OrganChips & #DigitalTwins can overcome the limitations of animal experiments in #DrugDiscovery, highlight real-world applications, limitations, & strategies to make #AI innovations more reliable & scalable. 🧪
doi.org/10.1016/j.dr...

🧪We working to improve cardiovascular care with the Longitudinal Hemodynamic Mapping Framework—combining wearables + #HPC to simulate millions of heartbeats in real time. Watch the video or read the blog to see how digital twins are reshaping heart health.

🔗 duke.is/lhmfblog

#DigitalTwins #CDHI

🧪 ⚛️ New work led by former Randles Lab postdoc Arash Ghorbannia: ML models predict iFR/FFR in coronary bifurcations using only pre-op anatomy. No wires needed—just anatomy to insight.

📄 duke.is/mlbifurcatio...
#DigitalTwins #ML4Health #Cardiology #RandlesLab

🧪Wires in arteries? Not always necessary.

We validated HARVEY—a simulation that estimates FFR from angiography data.

✅ AUC 0.91
✅ 90.2% PPV
✅ 95.4% specificity

Noninvasive. Accurate. From routine images.

🔗 duke.is/jaha24

#DigitalTwins #Cardiology

Excited to share that two papers from our group were accepted to #ICCS2025! 🧪

Congrats to Aristotle Martin and Samreen Mahmud on leading work in adaptive physics for cancer transport and digital twins for single-cell analysis. More soon! 🎉

#DigitalTwins #CCDHI #CompHealth @dukeubme.bsky.social

🧪 At Duke, researchers are using digital twins—virtual replicas of human organs and systems—to study disease, simulate treatments, and push the boundaries of biomedical discovery.

🔗 duke.is/twins

#DigitalTwins #Research #ComputationalHealth @dukeengineering.bsky.social

Excited to share our latest work on how arterial waveform shape impacts blood flow simulations. 🩸

We pinpoint which parts of the waveform most influence hemodynamics—across coronary, carotid & pulmonary arteries.

🔗 duke.is/wavelet
#DigitalTwins #CFD #HPC #CompHealth @dukeubme.bsky.social 🧪

🧪 🚨 New paper alert! 🚨
Our latest work on HarVI—the newest tool in our digital twin ecosystem with HARVEY + HarVis—is now out!

🔗 duke.is/jcsharvi

#DigitalTwins #ComputationalHealth @dukeubme.bsky.social #AIinMedicine

🧪 Nvidia and Mayo Clinic join forces to revolutionize pathology with AI, creating #DigitalTwins for clinical trials, training, and surgery planning. Powered by DGX B200 and MONAI, they aim to enhance diagnostics and care. 🩺💻

🚨 In the AI era, we think that precision medicine must balance data-driven insights with model-informed strategies.

#ComplexSystems science bridges this gap, offering explainable, dynamic models for personalized care. #PrecisionMedicine #DigitalTwins 🧪 #MedSky #NetSky

👉 rdcu.be/d6CJJ

🧵 1/

CropCraft: Inverse Procedural Modeling for 3D Reconstruction of #Crop Plants

by Albert J. Zhai, Xinlei Wang, Kaiyuan Li, Zhao Jiang, Junxiong Zhou, Sheng Wang, Zhenong Jin, Kaiyu Guan, Shenlong Wang

https://buff.ly/414pDGa via @arxiv-cs-cv.bsky.social #PlantScience 🧪 #DigitalTwins

I got to chat with Dean Jerry Lynch about the transformative potential of #DigitalTwins, our new Center for Computational and Digital Health Innovation, and, of course, some @dukembb.bsky.social. 🎥 Watch our conversation here: www.youtube.com/watch?v=JTGe...

#HealthInnovation #DukeEngineering🧪

🧪 Jeff Elton, CEO of ConcertAI, foresees AI and digital twins revolutionizing health care.

#DigitalTwins could simulate trials, cutting costs and boosting success, while AI powers precision medicine and smarter decisions.🩺💻 #MLSky

🧪 #DigitalTwins are reshaping health care innovation, aiding drug development and tackling data disparities for underserved patients.

Despite challenges like regulation and data quality, experts see immense promise in this technology.🩺🖥️