#Crelox
/ rant on:
Abbreviating cis-regulatory elements as *CRE* is a terrible abbreviation in a field that uses *Cre* recombinase as major lineage trace tool. 🐭🐟🧬
/ rant off

#devbio #MakeMoreTransgenics #Crelox #enhancers
March 17, 2025 at 11:08 PM
#SOBP2025

E.g. chr15q11-13 CNV associated with angelman and prader-willi syndromes. Can model in mice with validity (equivalent region on chr7, can generate CNV using CreLox system) and measure mouse biological and behavioural phenotypes.
April 24, 2025 at 2:09 PM