LOF Slc35a2 in oligodendrocytes results in severe hypomyelination, a reduction of oligodendrocytes, and reactive gliosis.
doi.org/10.1111/epi....

#epilepsy #ILAE #epilepsia #hypomyelination #malformations #corticaldevelopment #MOGHE #Slc35a2

🧠 Scientific seminar @ Cajal Institute with
Dr. Teresa Guillamón (Cajal Institute/CNC): “Spontaneous activity shapes sensory circuits in the developing cortex.”
🗓 Fri, Oct 24 – 12:30 PM
Join us!
#Neuroscience #CorticalDevelopment #CNC #InstitutoCajal

Abnormal HCN4 channel expression is observed at both P21 and P28 in RhebS16H neurons.
doi.org/10.1111/epi....

#epilepsy #epilepsia #ILAE #corticaldevelopment #focalcorticaldysplasia #HCNchannels #mTOR #tuberoussclerosiscomplex

Just got back from the @corticodevelopment.bsky.social conference in Giardini Naxos — such an inspiring and insightful experience. Grateful for the people, the ideas, and (of course) the Sicilian food! 🇮🇹🧠✨ #CorticalDevelopment #Sicily

New paper led by Dr. Yu Gao, a scientist in my lab, on single cell #patch-seq and #multiomics of #primate #corticaldevelopment and assessment of #autism gene #CHD8. authors.elsevier.com/c/1l7dg3BtfH...

Thanks to @itsmeawais.bsky.social and Lucia Gomez who carried out this work, and @silvianeuro.bsky.social and @mveronicapravata.bsky.social for the organoid assays.
Hope you enjoy the read and let us know what you think!
#Neuroscience #CorticalDevelopment #Evolution #EvoDevo