#CellGenomics
Sensitive dissection of a genomic regulatory landscape using bulk and targeted single-cell activation. #GenomicRegulation #Genomics #SingleCell #RNAseq #CellGenomics 🧪🧬 🖥️
www.cell.com/cell-genomic...
October 24, 2025 at 11:15 AM
Galaxy single-cell & spatial omics community update: Navigating new frontiers in 2025. #SingelCellOmics #SpatialOmics #Genomics #Bioinformatics #Training #Galaxy #CellGenomics 🧪🧬 🖥️
www.cell.com/cell-genomic...
October 24, 2025 at 10:30 AM
The Galaxy single-cell and spatial omics community (SPOC) is thrilled to share the latest updates on tools, datasets, and collaborative initiatives driving open and reproducible single-cell and spatial omics research in 2025.
https://galaxyproject.org/news/2025-10-14-spoc-cellgenomics/ (1/2)
October 17, 2025 at 7:17 AM
Dusa’s study is on the cover of this month’s #CellGenomics! Check it out if you haven’t had the chance yet!

www.cell.com/issue/S2666-...
October 10, 2025 at 9:32 AM
#ResultatScientifique 🔎| Le complexe CST protège l’ADN en réparant les cassures même après dégradation partielle, limitant ainsi les mutations dangereuses 🧬
✍️ @zhouxu.bsky.social
📕 @CellGenomics | buff.ly/84geAXj
Le complexe CST, un acteur inattendu de la réparation de l’ADN
Réparer l’ADN endommagé est un processus essentiel à l’intégrité du génome, qui peut être dérégulé dans les cancers.
www.insb.cnrs.fr
October 7, 2025 at 2:36 PM
#CellTypeAnnotation

SIMS
Scalable, Interpretable Machine learning for Single cell
github.com/braingeneers...

TabNet attention-based
Temperature scaling of trained network
Automated gene intersection

vs Seurat scANVI scVI Scnym Scibet SingleR scBERT

#CellGenomics 2025
www.cell.com/cell-genomic...
September 24, 2025 at 7:25 PM
Researchers at BC Cancer, Vancouver Prostate Centre, and UBC have identified a key regulator of epigenetic and transcriptional reprogramming in neuroendocrine prostate cancer (#NEPC) transdifferentiation.

🖇️ Abstract in CellGenomics: bit.ly/3TJx3K1
July 22, 2025 at 3:44 PM
@agacita.bsky.social & I preview: "Parental autoimmunity genetics & offspring T1D risk" www.cell.com/cell-genomic... for new #CellGenomics study: "Effects of parental autoimmune diseases on T1D in offspring can be partially explained by HLA & non-HLA polymorphisms" www.cell.com/cell-genomic...
Effects of parental autoimmune diseases on type 1 diabetes in offspring can be partially explained by HLA and non-HLA polymorphisms
Leveraging Finnish nationwide multi-generational registers and the biobanks of FinnGen, Wang, Liu, et al. investigated the effect of parental autoimmune diseases on offspring T1D. Their creative and r...
www.cell.com
June 11, 2025 at 3:14 PM
New #CellGenomics paper: Extensive differential gene expression and regulation by sex in human skeletal muscle. #Myoblue tinyurl.com/43yrj6kp
Extensive differential gene expression and regulation by sex in human skeletal muscle
Hanks et al. leveraged bulk and single-nucleus RNA-seq and single-nucleus ATAC-seq data from 281 skeletal muscle biopsies to identify widespread sex differences in gene expression and regulation at th...
tinyurl.com
June 5, 2025 at 9:07 PM
🧬 New tool to generate aneuploidies and analyse their impact on development.

The tool created by @milanlab.bsky.social helps better understand this phenomenon, which is the main cause of spontaneous miscarriage.

📰 Published in #CellGenomics by #IRBBarcelona

Read the news ➡️ shorturl.at/Ektif

👇
June 3, 2025 at 3:23 PM
📄The journal #CellGenomics publishes a study with the participation of groups Corominas and Serras @geneticsub.bsky.social on "Sequential activation of transcription factors promotes liver regeneration through specific and developmental enhancers" #PapersBiologiaUB

🔗 www.cell.com/cell-genomic...
May 28, 2025 at 10:17 AM
Want to dive deeper? Our open-source, Dockerized implementation ensures an easy setup. If you’re tackling massive single-cell data and want a robust, interpretable way to find real biological signal, CSI-GEP is for you. Find the full paper at @CellGenomics #SingleCell 6/6
January 10, 2025 at 7:47 PM
Unsatisfied with UMAPs and ‘language models’ for single-cell RNA-seq? Looking for a better way to model your data? Check out CSI-GEP—our new approach just published in @CellGenomics 1/6:
www.cell.com/cell-genomic...
CSI-GEP: A GPU-based unsupervised machine learning approach for recovering gene expression programs in atlas-scale single-cell RNA-seq data
Liu et al. develop CSI-GEP, an algorithm for recovering gene expression programs (GEPs) from single-cell RNA-seq data. GEPs can correspond to cell types or the activity of biological processes. CSI-GEP provides a better model for single-cell RNA-seq data compared to hard clustering. It outperforms existing methods in simulated and real data.
www.cell.com
January 10, 2025 at 7:45 PM
#RaynaudsSyndrome GWAS
GTEx-eQTL scRNAseq ISH->
ADRA2A/α2 Adrenergic receptors->
Expressed in distal coronary/skin arteriolar #SmoothMuscleCell

⏫SMC contractility under cold stress (28°C)
SNP CRISPR to modulate transcript level

#CellGenomics 2024
www.sciencedirect.com/science/arti...
September 1, 2024 at 11:05 PM
A new episode in our series on the evolution of mushrooms & #JGI #1KFG project has been released today in
@CellGenomics
... Unearthing bonnet mushroom evolution.
A huge collaboration worldwide
June 27, 2024 at 4:14 PM
Our paper just out in @CellGenomics addresses the obesity FAIM2 locus, which we show confers a stronger effect in children than in adults. Sheridan Littleton reports its functional characterization in the challenging hypothalamic context www.cell.com/cell-genomic...
Variant-to-function analysis of the childhood obesity chr12q13 locus implicates rs7132908 as a causal variant within the 3′ UTR of FAIM2
A locus on chr12q13 is strongly associated with childhood obesity by genome-wide associate studies. Littleton et al. identified a causal variant at this locus, which regulates gene expression in neura...
www.cell.com
May 1, 2024 at 3:35 PM
I'm so excited to announce that our story on LINE-1 DNA methylation has been published in @CellGenomics 🥳🥳

With @retrogenomics.bsky.social @aurelien-doucet.bsky.social and all other authors.

Enjoy the reading!

www.cell.com/cell-genomic...

See original thread below.
February 5, 2024 at 10:03 AM
Disease-specific selective vulnerability and neuroimmune pathways in dementia revealed by single cellgenomics https://www.biorxiv.org/content/10.1101/2023.09.29.560245v1
Disease-specific selective vulnerability and neuroimmune pathways in dementia revealed by single cellgenomics https://www.biorxiv.org/content/10.1101/2023.09.29.560245v1
The development of successful therapeutics for dementias requires an understanding of their shared a
www.biorxiv.org
September 30, 2023 at 10:15 AM
Disease-specific selective vulnerability and neuroimmune pathways in dementia revealed by single cellgenomics https://www.biorxiv.org/content/10.1101/2023.09.29.560245v1
Disease-specific selective vulnerability and neuroimmune pathways in dementia revealed by single cellgenomics https://www.biorxiv.org/content/10.1101/2023.09.29.560245v1
The development of successful therapeutics for dementias requires an understanding of their shared a
www.biorxiv.org
September 30, 2023 at 10:15 AM
🤗 Check out the new ⁦@CellGenomics⁩ ⁦@GA4GH⁩ special issue: making responsible #data sharing 🌏 to advance #genomics a reality!

Very proud of the contribution ⁦@AusGenomics⁩ makes internationally as ⁦@GA4GH⁩ driver project 🇦🇺...
December 20, 2024 at 3:26 PM
Excited to share final form of our work in @CellGenomics on the regulation of the proteome in genetically diverse mice!

Regulation of protein abundance in genetically diverse mouse populationsPlease see prior thread:

x.com/grkeele/status… cell.com/cell-genomics/…
Regulation of protein abundance in genetically diverse mouse populations
Keele et al. report quantitative profiling of protein abundance in liver tissue from genetically diverse mouse populations, powerful resources for characterizing protein regulation. They map QTLs for individual proteins and complexes and find conservation of local genetic effects and sex differences for individual proteins across inbred and outbred mice.
www.cell.com
March 8, 2025 at 1:57 AM