Sensitive dissection of a genomic regulatory landscape using bulk and targeted single-cell activation. #GenomicRegulation #Genomics #SingleCell #RNAseq #CellGenomics 🧪🧬 🖥️
www.cell.com/cell-genomic...
www.cell.com/cell-genomic...
October 24, 2025 at 11:15 AM
Sensitive dissection of a genomic regulatory landscape using bulk and targeted single-cell activation. #GenomicRegulation #Genomics #SingleCell #RNAseq #CellGenomics 🧪🧬 🖥️
www.cell.com/cell-genomic...
www.cell.com/cell-genomic...
Galaxy single-cell & spatial omics community update: Navigating new frontiers in 2025. #SingelCellOmics #SpatialOmics #Genomics #Bioinformatics #Training #Galaxy #CellGenomics 🧪🧬 🖥️
www.cell.com/cell-genomic...
www.cell.com/cell-genomic...
October 24, 2025 at 10:30 AM
Galaxy single-cell & spatial omics community update: Navigating new frontiers in 2025. #SingelCellOmics #SpatialOmics #Genomics #Bioinformatics #Training #Galaxy #CellGenomics 🧪🧬 🖥️
www.cell.com/cell-genomic...
www.cell.com/cell-genomic...
The Galaxy single-cell and spatial omics community (SPOC) is thrilled to share the latest updates on tools, datasets, and collaborative initiatives driving open and reproducible single-cell and spatial omics research in 2025.
https://galaxyproject.org/news/2025-10-14-spoc-cellgenomics/ (1/2)
https://galaxyproject.org/news/2025-10-14-spoc-cellgenomics/ (1/2)
October 17, 2025 at 7:17 AM
The Galaxy single-cell and spatial omics community (SPOC) is thrilled to share the latest updates on tools, datasets, and collaborative initiatives driving open and reproducible single-cell and spatial omics research in 2025.
https://galaxyproject.org/news/2025-10-14-spoc-cellgenomics/ (1/2)
https://galaxyproject.org/news/2025-10-14-spoc-cellgenomics/ (1/2)
Dusa’s study is on the cover of this month’s #CellGenomics! Check it out if you haven’t had the chance yet!
www.cell.com/issue/S2666-...
www.cell.com/issue/S2666-...
October 10, 2025 at 9:32 AM
Dusa’s study is on the cover of this month’s #CellGenomics! Check it out if you haven’t had the chance yet!
www.cell.com/issue/S2666-...
www.cell.com/issue/S2666-...
#ResultatScientifique 🔎| Le complexe CST protège l’ADN en réparant les cassures même après dégradation partielle, limitant ainsi les mutations dangereuses 🧬
✍️ @zhouxu.bsky.social
📕 @CellGenomics | buff.ly/84geAXj
✍️ @zhouxu.bsky.social
📕 @CellGenomics | buff.ly/84geAXj
Le complexe CST, un acteur inattendu de la réparation de l’ADN
Réparer l’ADN endommagé est un processus essentiel à l’intégrité du génome, qui peut être dérégulé dans les cancers.
www.insb.cnrs.fr
October 7, 2025 at 2:36 PM
#ResultatScientifique 🔎| Le complexe CST protège l’ADN en réparant les cassures même après dégradation partielle, limitant ainsi les mutations dangereuses 🧬
✍️ @zhouxu.bsky.social
📕 @CellGenomics | buff.ly/84geAXj
✍️ @zhouxu.bsky.social
📕 @CellGenomics | buff.ly/84geAXj
#CellTypeAnnotation
SIMS
Scalable, Interpretable Machine learning for Single cell
github.com/braingeneers...
TabNet attention-based
Temperature scaling of trained network
Automated gene intersection
vs Seurat scANVI scVI Scnym Scibet SingleR scBERT
#CellGenomics 2025
www.cell.com/cell-genomic...
SIMS
Scalable, Interpretable Machine learning for Single cell
github.com/braingeneers...
TabNet attention-based
Temperature scaling of trained network
Automated gene intersection
vs Seurat scANVI scVI Scnym Scibet SingleR scBERT
#CellGenomics 2025
www.cell.com/cell-genomic...
September 24, 2025 at 7:25 PM
#CellTypeAnnotation
SIMS
Scalable, Interpretable Machine learning for Single cell
github.com/braingeneers...
TabNet attention-based
Temperature scaling of trained network
Automated gene intersection
vs Seurat scANVI scVI Scnym Scibet SingleR scBERT
#CellGenomics 2025
www.cell.com/cell-genomic...
SIMS
Scalable, Interpretable Machine learning for Single cell
github.com/braingeneers...
TabNet attention-based
Temperature scaling of trained network
Automated gene intersection
vs Seurat scANVI scVI Scnym Scibet SingleR scBERT
#CellGenomics 2025
www.cell.com/cell-genomic...
P. Sumazin, H-S Chiu, S. Somvanshi et al discovered an unexpected way long noncoding #RNA regulates #geneExpression. #cancer #BigHorn @bcmhouston.bsky.social #TexasChildrens #CellGenomics @rnasociety.bsky.social phys.org/news/2025-08...
Long non-coding RNAs reveal an unexpected way to regulate gene expression
Long non-coding RNAs (lncRNA) are a type of RNA molecule that do not carry instructions to make proteins. Instead, they influence how other genes are expressed. There are tens of thousands of lncRNAs ...
phys.org
August 6, 2025 at 9:17 PM
P. Sumazin, H-S Chiu, S. Somvanshi et al discovered an unexpected way long noncoding #RNA regulates #geneExpression. #cancer #BigHorn @bcmhouston.bsky.social #TexasChildrens #CellGenomics @rnasociety.bsky.social phys.org/news/2025-08...
P. Sumazin, H-S Chiu, S. Somvanshi et al discovered an unexpected way long noncoding #RNA regulates #geneExpression #cancer #BigHorn @bcmhouston.bsky.social #TexasChildrensHospital #CellGenomics blogs.bcm.edu/2025/08/05/f...
Long non-coding RNAs reveal an unexpected way to regulate gene expression
The findings revealed that lncRNAs seem to regulate gene expression in a coordinated manner that had not been seen before.
blogs.bcm.edu
August 5, 2025 at 5:13 PM
P. Sumazin, H-S Chiu, S. Somvanshi et al discovered an unexpected way long noncoding #RNA regulates #geneExpression #cancer #BigHorn @bcmhouston.bsky.social #TexasChildrensHospital #CellGenomics blogs.bcm.edu/2025/08/05/f...
Researchers at BC Cancer, Vancouver Prostate Centre, and UBC have identified a key regulator of epigenetic and transcriptional reprogramming in neuroendocrine prostate cancer (#NEPC) transdifferentiation.
🖇️ Abstract in CellGenomics: bit.ly/3TJx3K1
🖇️ Abstract in CellGenomics: bit.ly/3TJx3K1
July 22, 2025 at 3:44 PM
Researchers at BC Cancer, Vancouver Prostate Centre, and UBC have identified a key regulator of epigenetic and transcriptional reprogramming in neuroendocrine prostate cancer (#NEPC) transdifferentiation.
🖇️ Abstract in CellGenomics: bit.ly/3TJx3K1
🖇️ Abstract in CellGenomics: bit.ly/3TJx3K1
@agacita.bsky.social & I preview: "Parental autoimmunity genetics & offspring T1D risk" www.cell.com/cell-genomic... for new #CellGenomics study: "Effects of parental autoimmune diseases on T1D in offspring can be partially explained by HLA & non-HLA polymorphisms" www.cell.com/cell-genomic...
Effects of parental autoimmune diseases on type 1 diabetes in offspring can be partially explained by HLA and non-HLA polymorphisms
Leveraging Finnish nationwide multi-generational registers and the biobanks of FinnGen,
Wang, Liu, et al. investigated the effect of parental autoimmune diseases on offspring
T1D. Their creative and r...
www.cell.com
June 11, 2025 at 3:14 PM
@agacita.bsky.social & I preview: "Parental autoimmunity genetics & offspring T1D risk" www.cell.com/cell-genomic... for new #CellGenomics study: "Effects of parental autoimmune diseases on T1D in offspring can be partially explained by HLA & non-HLA polymorphisms" www.cell.com/cell-genomic...
New #CellGenomics paper: Extensive differential gene expression and regulation by sex in human skeletal muscle. #Myoblue tinyurl.com/43yrj6kp
Extensive differential gene expression and regulation by sex in human skeletal muscle
Hanks et al. leveraged bulk and single-nucleus RNA-seq and single-nucleus ATAC-seq
data from 281 skeletal muscle biopsies to identify widespread sex differences in gene
expression and regulation at th...
tinyurl.com
June 5, 2025 at 9:07 PM
New #CellGenomics paper: Extensive differential gene expression and regulation by sex in human skeletal muscle. #Myoblue tinyurl.com/43yrj6kp
🧬 New tool to generate aneuploidies and analyse their impact on development.
The tool created by @milanlab.bsky.social helps better understand this phenomenon, which is the main cause of spontaneous miscarriage.
📰 Published in #CellGenomics by #IRBBarcelona
Read the news ➡️ shorturl.at/Ektif
👇
The tool created by @milanlab.bsky.social helps better understand this phenomenon, which is the main cause of spontaneous miscarriage.
📰 Published in #CellGenomics by #IRBBarcelona
Read the news ➡️ shorturl.at/Ektif
👇
June 3, 2025 at 3:23 PM
🧬 New tool to generate aneuploidies and analyse their impact on development.
The tool created by @milanlab.bsky.social helps better understand this phenomenon, which is the main cause of spontaneous miscarriage.
📰 Published in #CellGenomics by #IRBBarcelona
Read the news ➡️ shorturl.at/Ektif
👇
The tool created by @milanlab.bsky.social helps better understand this phenomenon, which is the main cause of spontaneous miscarriage.
📰 Published in #CellGenomics by #IRBBarcelona
Read the news ➡️ shorturl.at/Ektif
👇
📄The journal #CellGenomics publishes a study with the participation of groups Corominas and Serras @geneticsub.bsky.social on "Sequential activation of transcription factors promotes liver regeneration through specific and developmental enhancers" #PapersBiologiaUB
🔗 www.cell.com/cell-genomic...
🔗 www.cell.com/cell-genomic...
May 28, 2025 at 10:17 AM
📄The journal #CellGenomics publishes a study with the participation of groups Corominas and Serras @geneticsub.bsky.social on "Sequential activation of transcription factors promotes liver regeneration through specific and developmental enhancers" #PapersBiologiaUB
🔗 www.cell.com/cell-genomic...
🔗 www.cell.com/cell-genomic...
Want to dive deeper? Our open-source, Dockerized implementation ensures an easy setup. If you’re tackling massive single-cell data and want a robust, interpretable way to find real biological signal, CSI-GEP is for you. Find the full paper at @CellGenomics #SingleCell 6/6
January 10, 2025 at 7:47 PM
Want to dive deeper? Our open-source, Dockerized implementation ensures an easy setup. If you’re tackling massive single-cell data and want a robust, interpretable way to find real biological signal, CSI-GEP is for you. Find the full paper at @CellGenomics #SingleCell 6/6
Unsatisfied with UMAPs and ‘language models’ for single-cell RNA-seq? Looking for a better way to model your data? Check out CSI-GEP—our new approach just published in @CellGenomics 1/6:
www.cell.com/cell-genomic...
www.cell.com/cell-genomic...
CSI-GEP: A GPU-based unsupervised machine learning approach for recovering gene expression programs in atlas-scale single-cell RNA-seq data
Liu et al. develop CSI-GEP, an algorithm for recovering gene expression programs (GEPs) from single-cell RNA-seq data. GEPs can correspond to cell types or the activity of biological processes. CSI-GEP provides a better model for single-cell RNA-seq data compared to hard clustering. It outperforms existing methods in simulated and real data.
www.cell.com
January 10, 2025 at 7:45 PM
Unsatisfied with UMAPs and ‘language models’ for single-cell RNA-seq? Looking for a better way to model your data? Check out CSI-GEP—our new approach just published in @CellGenomics 1/6:
www.cell.com/cell-genomic...
www.cell.com/cell-genomic...
Leveraging genomes to support conservation and bioeconomy policies in a megadiverse country. #Genomics #BiodiversityConservation #GenomicsBrazilianBiodiversity #CellGenomics 🧬
www.cell.com/cell-genomic...
www.cell.com/cell-genomic...
Leveraging genomes to support conservation and bioeconomy policies in a megadiverse country
Vilaça et al. described a unique private-public initiative, the Genomics of the Brazilian
Biodiversity (GBB) consortium. They outline the goals and challenges faced so far
and discuss the gaps concern...
www.cell.com
November 16, 2024 at 5:35 PM
Leveraging genomes to support conservation and bioeconomy policies in a megadiverse country. #Genomics #BiodiversityConservation #GenomicsBrazilianBiodiversity #CellGenomics 🧬
www.cell.com/cell-genomic...
www.cell.com/cell-genomic...
#RaynaudsSyndrome GWAS
GTEx-eQTL scRNAseq ISH->
ADRA2A/α2 Adrenergic receptors->
Expressed in distal coronary/skin arteriolar #SmoothMuscleCell
⏫SMC contractility under cold stress (28°C)
SNP CRISPR to modulate transcript level
#CellGenomics 2024
www.sciencedirect.com/science/arti...
GTEx-eQTL scRNAseq ISH->
ADRA2A/α2 Adrenergic receptors->
Expressed in distal coronary/skin arteriolar #SmoothMuscleCell
⏫SMC contractility under cold stress (28°C)
SNP CRISPR to modulate transcript level
#CellGenomics 2024
www.sciencedirect.com/science/arti...
September 1, 2024 at 11:05 PM
#RaynaudsSyndrome GWAS
GTEx-eQTL scRNAseq ISH->
ADRA2A/α2 Adrenergic receptors->
Expressed in distal coronary/skin arteriolar #SmoothMuscleCell
⏫SMC contractility under cold stress (28°C)
SNP CRISPR to modulate transcript level
#CellGenomics 2024
www.sciencedirect.com/science/arti...
GTEx-eQTL scRNAseq ISH->
ADRA2A/α2 Adrenergic receptors->
Expressed in distal coronary/skin arteriolar #SmoothMuscleCell
⏫SMC contractility under cold stress (28°C)
SNP CRISPR to modulate transcript level
#CellGenomics 2024
www.sciencedirect.com/science/arti...
Our paper just out in @CellGenomics addresses the obesity FAIM2 locus, which we show confers a stronger effect in children than in adults. Sheridan Littleton reports its functional characterization in the challenging hypothalamic context www.cell.com/cell-genomic...
Variant-to-function analysis of the childhood obesity chr12q13 locus implicates rs7132908 as a causal variant within the 3′ UTR of FAIM2
A locus on chr12q13 is strongly associated with childhood obesity by genome-wide associate
studies. Littleton et al. identified a causal variant at this locus, which regulates
gene expression in neura...
www.cell.com
May 1, 2024 at 3:35 PM
Our paper just out in @CellGenomics addresses the obesity FAIM2 locus, which we show confers a stronger effect in children than in adults. Sheridan Littleton reports its functional characterization in the challenging hypothalamic context www.cell.com/cell-genomic...
I'm so excited to announce that our story on LINE-1 DNA methylation has been published in @CellGenomics 🥳🥳
With @retrogenomics.bsky.social @aurelien-doucet.bsky.social and all other authors.
Enjoy the reading!
www.cell.com/cell-genomic...
See original thread below.
With @retrogenomics.bsky.social @aurelien-doucet.bsky.social and all other authors.
Enjoy the reading!
www.cell.com/cell-genomic...
See original thread below.
February 5, 2024 at 10:03 AM
I'm so excited to announce that our story on LINE-1 DNA methylation has been published in @CellGenomics 🥳🥳
With @retrogenomics.bsky.social @aurelien-doucet.bsky.social and all other authors.
Enjoy the reading!
www.cell.com/cell-genomic...
See original thread below.
With @retrogenomics.bsky.social @aurelien-doucet.bsky.social and all other authors.
Enjoy the reading!
www.cell.com/cell-genomic...
See original thread below.
Disease-specific selective vulnerability and neuroimmune pathways in dementia revealed by single cellgenomics https://www.biorxiv.org/content/10.1101/2023.09.29.560245v1
Disease-specific selective vulnerability and neuroimmune pathways in dementia revealed by single cellgenomics https://www.biorxiv.org/content/10.1101/2023.09.29.560245v1
The development of successful therapeutics for dementias requires an understanding of their shared a
www.biorxiv.org
September 30, 2023 at 10:15 AM
Disease-specific selective vulnerability and neuroimmune pathways in dementia revealed by single cellgenomics https://www.biorxiv.org/content/10.1101/2023.09.29.560245v1
Disease-specific selective vulnerability and neuroimmune pathways in dementia revealed by single cellgenomics https://www.biorxiv.org/content/10.1101/2023.09.29.560245v1
Disease-specific selective vulnerability and neuroimmune pathways in dementia revealed by single cellgenomics https://www.biorxiv.org/content/10.1101/2023.09.29.560245v1
The development of successful therapeutics for dementias requires an understanding of their shared a
www.biorxiv.org
September 30, 2023 at 10:15 AM
Disease-specific selective vulnerability and neuroimmune pathways in dementia revealed by single cellgenomics https://www.biorxiv.org/content/10.1101/2023.09.29.560245v1
Excited to share final form of our work in @CellGenomics on the regulation of the proteome in genetically diverse mice!
Regulation of protein abundance in genetically diverse mouse populationsPlease see prior thread:
x.com/grkeele/status… cell.com/cell-genomics/…
Regulation of protein abundance in genetically diverse mouse populationsPlease see prior thread:
x.com/grkeele/status… cell.com/cell-genomics/…
Regulation of protein abundance in genetically diverse mouse populations
Keele et al. report quantitative profiling of protein abundance in liver tissue from genetically diverse mouse populations, powerful resources for characterizing protein regulation. They map QTLs for individual proteins and complexes and find conservation of local genetic effects and sex differences for individual proteins across inbred and outbred mice.
www.cell.com
March 8, 2025 at 1:57 AM
Excited to share final form of our work in @CellGenomics on the regulation of the proteome in genetically diverse mice!
Regulation of protein abundance in genetically diverse mouse populationsPlease see prior thread:
x.com/grkeele/status… cell.com/cell-genomics/…
Regulation of protein abundance in genetically diverse mouse populationsPlease see prior thread:
x.com/grkeele/status… cell.com/cell-genomics/…