It's always a pleasure to spend the day out with the lab. Today was all about sharing our research and hearing about the other work going on in the department.
I was able to share and get valuable feedback on our latest insights on NINJ1 in #celldeath and #inflammation.
I was able to share and get valuable feedback on our latest insights on NINJ1 in #celldeath and #inflammation.
It’s DIB day! The annual conference for our department @dib-unil.bsky.social. Lovely day (and view!) at the Lausanne Olympic museum exchanging with our colleagues. Plus a stellar presentation on NINJ1 by our own @elliottbernard.bsky.social 🔬!
November 11, 2025 at 9:46 PM
It's always a pleasure to spend the day out with the lab. Today was all about sharing our research and hearing about the other work going on in the department.
I was able to share and get valuable feedback on our latest insights on NINJ1 in #celldeath and #inflammation.
I was able to share and get valuable feedback on our latest insights on NINJ1 in #celldeath and #inflammation.
This week´s issue of Biomednews on everything related to #CellDeath: biomed.news/bims-cediti/...
Highlight of this week: Structural insights into the atypical filament assembly of pyrin domain-containing IFI16, and its difference from inflammasome-forming PYDs:
Highlight of this week: Structural insights into the atypical filament assembly of pyrin domain-containing IFI16, and its difference from inflammasome-forming PYDs:
Structural insights into the atypical filament assembly of pyrin domain-containing IFI16 | The EMBO Journal
imageimageThe pyrin domain (PYD)-containing interferon-inducible protein 16 (IFI16) has various
inflammasome-independent functions, while it has also been suggested as a DNA sensor
for inflammasome fo...
www.embopress.org
November 9, 2025 at 9:40 AM
This week´s issue of Biomednews on everything related to #CellDeath: biomed.news/bims-cediti/...
Highlight of this week: Structural insights into the atypical filament assembly of pyrin domain-containing IFI16, and its difference from inflammasome-forming PYDs:
Highlight of this week: Structural insights into the atypical filament assembly of pyrin domain-containing IFI16, and its difference from inflammasome-forming PYDs:
🧬 Just published in Advanced Science: New work from @linkermannlab.bsky.social showing that secondary necrosis can occur without Gasdermin E. A clear step forward in decoding regulated necrosis. #CellDeath #SecondaryNecrosis #GSDME #CaspaseInhibition #AdvancedScience #EditorPick shorturl.at/ITJe6
Secondary Necrosis Following Caspase‐Activation can Occur Independently of Gasdermin E
Secondary necrosis follows apoptosis, but its mechanism is unclear. This study shows that although gasdermin E is cleaved during this process, it is not required for membrane rupture. Across multiple...
advanced.onlinelibrary.wiley.com
November 4, 2025 at 3:02 PM
🧬 Just published in Advanced Science: New work from @linkermannlab.bsky.social showing that secondary necrosis can occur without Gasdermin E. A clear step forward in decoding regulated necrosis. #CellDeath #SecondaryNecrosis #GSDME #CaspaseInhibition #AdvancedScience #EditorPick shorturl.at/ITJe6
🔗To the original publication: t1p.de/jqhuo
#CellDeath #CancerResearch #Alzheimer #Parkinson #Neurodegeneration #PrecisionMedicine #HeartDisease #BNMRZ
#CellDeath #CancerResearch #Alzheimer #Parkinson #Neurodegeneration #PrecisionMedicine #HeartDisease #BNMRZ
November 4, 2025 at 10:12 AM
🔗To the original publication: t1p.de/jqhuo
#CellDeath #CancerResearch #Alzheimer #Parkinson #Neurodegeneration #PrecisionMedicine #HeartDisease #BNMRZ
#CellDeath #CancerResearch #Alzheimer #Parkinson #Neurodegeneration #PrecisionMedicine #HeartDisease #BNMRZ
New Switch for Natural Cell Death🧬
Programmed cell death (#apoptosis) protects us, but cancer cells can evade it. Researchers at #HelmholtzMunich & TUM discovered a new molecular switch controlling this process.
👉 t1p.de/3fxvc
@tum.de @natureportfolio.nature.com
#CellDeath #BNMRZ
Programmed cell death (#apoptosis) protects us, but cancer cells can evade it. Researchers at #HelmholtzMunich & TUM discovered a new molecular switch controlling this process.
👉 t1p.de/3fxvc
@tum.de @natureportfolio.nature.com
#CellDeath #BNMRZ
November 4, 2025 at 10:12 AM
New Switch for Natural Cell Death🧬
Programmed cell death (#apoptosis) protects us, but cancer cells can evade it. Researchers at #HelmholtzMunich & TUM discovered a new molecular switch controlling this process.
👉 t1p.de/3fxvc
@tum.de @natureportfolio.nature.com
#CellDeath #BNMRZ
Programmed cell death (#apoptosis) protects us, but cancer cells can evade it. Researchers at #HelmholtzMunich & TUM discovered a new molecular switch controlling this process.
👉 t1p.de/3fxvc
@tum.de @natureportfolio.nature.com
#CellDeath #BNMRZ
Over the past few months, I started to curate a weekly issue of the weekly issue of the BioMed News @biomednews.bsky.social on #CellDeath.
Highlight of this week: further mechanistic clarification of how viral infections can drive endogenous Z-NA production: www.nature.com/articles/s41...
Highlight of this week: further mechanistic clarification of how viral infections can drive endogenous Z-NA production: www.nature.com/articles/s41...
bims-cediti 2025-10-19 papers
biomed.news
October 26, 2025 at 1:11 PM
Over the past few months, I started to curate a weekly issue of the weekly issue of the BioMed News @biomednews.bsky.social on #CellDeath.
Highlight of this week: further mechanistic clarification of how viral infections can drive endogenous Z-NA production: www.nature.com/articles/s41...
Highlight of this week: further mechanistic clarification of how viral infections can drive endogenous Z-NA production: www.nature.com/articles/s41...
REVIEW🚨
The authors discuss the regulation and interplay of the metabolic #CellDeath pathways #ferroptosis, #disulfidptosis and #cuproptosis and explore how these mechanisms can be harnessed for cancer therapies.
@mdanderson.bsky.social
📖 ⬇️
https://bit.ly/3L3vN...
The authors discuss the regulation and interplay of the metabolic #CellDeath pathways #ferroptosis, #disulfidptosis and #cuproptosis and explore how these mechanisms can be harnessed for cancer therapies.
@mdanderson.bsky.social
📖 ⬇️
https://bit.ly/3L3vN...
October 22, 2025 at 2:46 PM
REVIEW🚨
The authors discuss the regulation and interplay of the metabolic #CellDeath pathways #ferroptosis, #disulfidptosis and #cuproptosis and explore how these mechanisms can be harnessed for cancer therapies.
@mdanderson.bsky.social
📖 ⬇️
https://bit.ly/3L3vN...
The authors discuss the regulation and interplay of the metabolic #CellDeath pathways #ferroptosis, #disulfidptosis and #cuproptosis and explore how these mechanisms can be harnessed for cancer therapies.
@mdanderson.bsky.social
📖 ⬇️
https://bit.ly/3L3vN...
6/9 But this trigger has a dark side.
Randal #Halfmann, who oversaw the work, observed that these #proteins don't always wait for a virus.
Given enough time—over a lifespan—they will spontaneously crystallize on their own. This misfire leads to #CellDeath and #inflammation.
#Science
Randal #Halfmann, who oversaw the work, observed that these #proteins don't always wait for a virus.
Given enough time—over a lifespan—they will spontaneously crystallize on their own. This misfire leads to #CellDeath and #inflammation.
#Science
October 22, 2025 at 4:52 AM
6/9 But this trigger has a dark side.
Randal #Halfmann, who oversaw the work, observed that these #proteins don't always wait for a virus.
Given enough time—over a lifespan—they will spontaneously crystallize on their own. This misfire leads to #CellDeath and #inflammation.
#Science
Randal #Halfmann, who oversaw the work, observed that these #proteins don't always wait for a virus.
Given enough time—over a lifespan—they will spontaneously crystallize on their own. This misfire leads to #CellDeath and #inflammation.
#Science
what do u know about #celldeath or #cancer
upcoming episode in the future
Was such a nice mix day with PhDs in different domains Marya Savyuk and Deba_ 💫🙌🏻
upcoming episode in the future
Was such a nice mix day with PhDs in different domains Marya Savyuk and Deba_ 💫🙌🏻
October 16, 2025 at 11:16 PM
what do u know about #celldeath or #cancer
upcoming episode in the future
Was such a nice mix day with PhDs in different domains Marya Savyuk and Deba_ 💫🙌🏻
upcoming episode in the future
Was such a nice mix day with PhDs in different domains Marya Savyuk and Deba_ 💫🙌🏻
'Death fold' proteins can make cells self-destruct. Scientists want to control them #Science #Biology #CellBiology #CellDeath #ProteinEngineering #Biotechnology
'Death fold' proteins can make cells self-destruct. Scientists want to control them
Scientists are hoping to treat diseases including cancer and Alzheimer's by influencing how cells make life-or-death decisions. (Image credit: faithiecannoise/iStockphoto)
purescience.news
October 16, 2025 at 5:45 PM
'Death fold' proteins can make cells self-destruct. Scientists want to control them #Science #Biology #CellBiology #CellDeath #ProteinEngineering #Biotechnology
Lioba Koerner, Xiaoming Li, Eveline Silnov, Lucie Laurien, and Manolis Pasparakis @unicologne.bsky.social reveal that a functional interplay of S161 and S166 phosphorylation events regulates RIPK1-dependent #CellDeath and #inflammation. rupress.org/jem/article/...
October 9, 2025 at 4:51 PM
Lioba Koerner, Xiaoming Li, Eveline Silnov, Lucie Laurien, and Manolis Pasparakis @unicologne.bsky.social reveal that a functional interplay of S161 and S166 phosphorylation events regulates RIPK1-dependent #CellDeath and #inflammation. rupress.org/jem/article/...
An overview of the evolution of #NuclearMedicine, FDA-approved & clinically investigated radionuclides, highlighting #radiopharmaceutical-induced #CellDeath mechanisms, their clinical applications, and future prospects. #PrecisionMedicine #medsky
#STTT #OpenAccess: doi.org/10.1038/s413...
#STTT #OpenAccess: doi.org/10.1038/s413...
October 6, 2025 at 5:19 AM
An overview of the evolution of #NuclearMedicine, FDA-approved & clinically investigated radionuclides, highlighting #radiopharmaceutical-induced #CellDeath mechanisms, their clinical applications, and future prospects. #PrecisionMedicine #medsky
#STTT #OpenAccess: doi.org/10.1038/s413...
#STTT #OpenAccess: doi.org/10.1038/s413...
The STING of death continues!
Thanks to @natrevrheum.nature.com (doi.org/10.1038/s415... & rdcu.be/eJjhl ) for highlighting our recent @nature.com paper (doi.org/10.1038/s415...) cell death inhibition as a therapy for autoinflammatory diseases (SAVI)
#immunity #celldeath #rheumatology #vasculitis
Thanks to @natrevrheum.nature.com (doi.org/10.1038/s415... & rdcu.be/eJjhl ) for highlighting our recent @nature.com paper (doi.org/10.1038/s415...) cell death inhibition as a therapy for autoinflammatory diseases (SAVI)
#immunity #celldeath #rheumatology #vasculitis
October 3, 2025 at 1:01 PM
The STING of death continues!
Thanks to @natrevrheum.nature.com (doi.org/10.1038/s415... & rdcu.be/eJjhl ) for highlighting our recent @nature.com paper (doi.org/10.1038/s415...) cell death inhibition as a therapy for autoinflammatory diseases (SAVI)
#immunity #celldeath #rheumatology #vasculitis
Thanks to @natrevrheum.nature.com (doi.org/10.1038/s415... & rdcu.be/eJjhl ) for highlighting our recent @nature.com paper (doi.org/10.1038/s415...) cell death inhibition as a therapy for autoinflammatory diseases (SAVI)
#immunity #celldeath #rheumatology #vasculitis
issues, since he's still immortal. his body doesn't naturally degrade, so the biggest issue is fuel.
soap has to feed regularly to prevent organ failure and celldeath, even moreso when siring a fledgling, as a lot of resources go into making venom and milk
on the topic of body waste though, —
soap has to feed regularly to prevent organ failure and celldeath, even moreso when siring a fledgling, as a lot of resources go into making venom and milk
on the topic of body waste though, —
October 3, 2025 at 8:13 AM
issues, since he's still immortal. his body doesn't naturally degrade, so the biggest issue is fuel.
soap has to feed regularly to prevent organ failure and celldeath, even moreso when siring a fledgling, as a lot of resources go into making venom and milk
on the topic of body waste though, —
soap has to feed regularly to prevent organ failure and celldeath, even moreso when siring a fledgling, as a lot of resources go into making venom and milk
on the topic of body waste though, —
September 25, 2025 at 9:26 AM
New publication from Santosh Chauhan Lab at Centre for Cellular and Molecular Biology with important contributions from Ramesh Yelagandula lab at CDFD. The study challenges the belief of irreversible cell death.
@embojournal.org
www.embopress.org/.../10.1038/...
#celldeath #cellrevival#regeneration
@embojournal.org
www.embopress.org/.../10.1038/...
#celldeath #cellrevival#regeneration
September 15, 2025 at 11:40 AM
New publication from Santosh Chauhan Lab at Centre for Cellular and Molecular Biology with important contributions from Ramesh Yelagandula lab at CDFD. The study challenges the belief of irreversible cell death.
@embojournal.org
www.embopress.org/.../10.1038/...
#celldeath #cellrevival#regeneration
@embojournal.org
www.embopress.org/.../10.1038/...
#celldeath #cellrevival#regeneration
The Human Apaf-1 Apoptosome Complex:
Seven DARK proteins assemble into a striking molecular wheel.
With cytochrome c and cofactors
.
A molecular fidget spinner 🌀
PDB ID: 3JBT
Rendered with @UCSFChimeraX
.
#sciart #proteinvisualization #molecularart #apoptosis #cellbiology #celldeath
Seven DARK proteins assemble into a striking molecular wheel.
With cytochrome c and cofactors
.
A molecular fidget spinner 🌀
PDB ID: 3JBT
Rendered with @UCSFChimeraX
.
#sciart #proteinvisualization #molecularart #apoptosis #cellbiology #celldeath
September 14, 2025 at 7:28 PM
The Human Apaf-1 Apoptosome Complex:
Seven DARK proteins assemble into a striking molecular wheel.
With cytochrome c and cofactors
.
A molecular fidget spinner 🌀
PDB ID: 3JBT
Rendered with @UCSFChimeraX
.
#sciart #proteinvisualization #molecularart #apoptosis #cellbiology #celldeath
Seven DARK proteins assemble into a striking molecular wheel.
With cytochrome c and cofactors
.
A molecular fidget spinner 🌀
PDB ID: 3JBT
Rendered with @UCSFChimeraX
.
#sciart #proteinvisualization #molecularart #apoptosis #cellbiology #celldeath
Researchers at ONJCRI, the University of Washington and @wehi-research.bsky.social have created novel "designer proteins" that can both activate and block cell death as required under different conditions.
➡️ Read the Science Advances paper: ow.ly/5glk50WSRnT
#CellDeath #Apoptosis #ONJCRI
➡️ Read the Science Advances paper: ow.ly/5glk50WSRnT
#CellDeath #Apoptosis #ONJCRI
September 8, 2025 at 6:00 AM
Researchers at ONJCRI, the University of Washington and @wehi-research.bsky.social have created novel "designer proteins" that can both activate and block cell death as required under different conditions.
➡️ Read the Science Advances paper: ow.ly/5glk50WSRnT
#CellDeath #Apoptosis #ONJCRI
➡️ Read the Science Advances paper: ow.ly/5glk50WSRnT
#CellDeath #Apoptosis #ONJCRI
Join us on Monday for @UAM_IBMiB
seminar of Takeshi Matsui from the Tokyo University of Technology to learn about keratinocyte-specific cell-death in formation of epidermal barrier! PhD students/postdocs are welcome for the cereer advice meeting! #cellDeath #corneoptosis #ID_UB
seminar of Takeshi Matsui from the Tokyo University of Technology to learn about keratinocyte-specific cell-death in formation of epidermal barrier! PhD students/postdocs are welcome for the cereer advice meeting! #cellDeath #corneoptosis #ID_UB
September 4, 2025 at 10:33 AM
Join us on Monday for @UAM_IBMiB
seminar of Takeshi Matsui from the Tokyo University of Technology to learn about keratinocyte-specific cell-death in formation of epidermal barrier! PhD students/postdocs are welcome for the cereer advice meeting! #cellDeath #corneoptosis #ID_UB
seminar of Takeshi Matsui from the Tokyo University of Technology to learn about keratinocyte-specific cell-death in formation of epidermal barrier! PhD students/postdocs are welcome for the cereer advice meeting! #cellDeath #corneoptosis #ID_UB
⏳ Just 3 days left! Don’t miss the chance to present your science at #ECDO2025 in Berlin.
Submit your abstract today 👉 www.ecdo.eu/ecdo2025/con...
#CellDeath #Berlin2025
Submit your abstract today 👉 www.ecdo.eu/ecdo2025/con...
#CellDeath #Berlin2025
August 29, 2025 at 11:55 AM
⏳ Just 3 days left! Don’t miss the chance to present your science at #ECDO2025 in Berlin.
Submit your abstract today 👉 www.ecdo.eu/ecdo2025/con...
#CellDeath #Berlin2025
Submit your abstract today 👉 www.ecdo.eu/ecdo2025/con...
#CellDeath #Berlin2025
Most autophagic cell death studies lack evidence of causality
➡️ buff.ly/hkLPhcj
#Autophagy #CellDeath #CellBiology
➡️ buff.ly/hkLPhcj
#Autophagy #CellDeath #CellBiology
August 28, 2025 at 9:58 AM
Most autophagic cell death studies lack evidence of causality
➡️ buff.ly/hkLPhcj
#Autophagy #CellDeath #CellBiology
➡️ buff.ly/hkLPhcj
#Autophagy #CellDeath #CellBiology
(3/3) This is an incredible opportunity to hear fresh insights from leaders in cell death research and connect with colleagues worldwide 🌍. We hope to see you there!
#ACDS #ECDO #CDDpress #Celldeath
#ACDS #ECDO #CDDpress #Celldeath
August 18, 2025 at 3:54 AM
(3/3) This is an incredible opportunity to hear fresh insights from leaders in cell death research and connect with colleagues worldwide 🌍. We hope to see you there!
#ACDS #ECDO #CDDpress #Celldeath
#ACDS #ECDO #CDDpress #Celldeath
(1/3) 🚨 We’re back with Edition #2 of our 2025 International Cell Death Seminar Series! 🚨
📅 Wednesday 3 Sept | 🦘 4:30pm AEST / 🌍 8:30am CEST
In collaboration with @ecdoorg.bsky.social + @CDDpress.
Flyer below ⬇️
#ACDS #CellDeath
📅 Wednesday 3 Sept | 🦘 4:30pm AEST / 🌍 8:30am CEST
In collaboration with @ecdoorg.bsky.social + @CDDpress.
Flyer below ⬇️
#ACDS #CellDeath
August 18, 2025 at 3:54 AM
(1/3) 🚨 We’re back with Edition #2 of our 2025 International Cell Death Seminar Series! 🚨
📅 Wednesday 3 Sept | 🦘 4:30pm AEST / 🌍 8:30am CEST
In collaboration with @ecdoorg.bsky.social + @CDDpress.
Flyer below ⬇️
#ACDS #CellDeath
📅 Wednesday 3 Sept | 🦘 4:30pm AEST / 🌍 8:30am CEST
In collaboration with @ecdoorg.bsky.social + @CDDpress.
Flyer below ⬇️
#ACDS #CellDeath
An overview of the evolution of #NuclearMedicine, FDA-approved & clinically investigated radionuclides, as well as #radiopharmaceuticals -induced #CellDeath mechanisms, their clinical applications, and future prospects. #PrecisionMedicine #medsky
#STTT #OpenAccess: www.nature.com/articles/s41...
#STTT #OpenAccess: www.nature.com/articles/s41...
August 9, 2025 at 10:00 PM
An overview of the evolution of #NuclearMedicine, FDA-approved & clinically investigated radionuclides, as well as #radiopharmaceuticals -induced #CellDeath mechanisms, their clinical applications, and future prospects. #PrecisionMedicine #medsky
#STTT #OpenAccess: www.nature.com/articles/s41...
#STTT #OpenAccess: www.nature.com/articles/s41...
Big congrats to Vinnie Graziano @vinnieviruses.bsky.social who led the project and huge thanks to our great collaborators: Jennifer Porat, Thomas Carell, Franck Barrat, Beiyan Zhou, Sivapriya Kailasan Vanaja, Michael Wilson, and Penghua Wang!! #innate_immunity #interferon #celldeath
August 6, 2025 at 3:39 PM
Big congrats to Vinnie Graziano @vinnieviruses.bsky.social who led the project and huge thanks to our great collaborators: Jennifer Porat, Thomas Carell, Franck Barrat, Beiyan Zhou, Sivapriya Kailasan Vanaja, Michael Wilson, and Penghua Wang!! #innate_immunity #interferon #celldeath