Promising results in patients with active #brainmetastases of various #tumour types. ☑️
A study led by #MedUniVienna shows that patritumab deruxtecan is effective in patients with #lungcancer & #breastcancer.
Details! ⬇️
📰 @thelancetoncol.bsky.social
A study led by #MedUniVienna shows that patritumab deruxtecan is effective in patients with #lungcancer & #breastcancer.
Details! ⬇️
📰 @thelancetoncol.bsky.social
New therapy for active brain metastases successfully tested
Read up on the study!
www.meduniwien.ac.at
October 28, 2025 at 3:19 PM
Promising results in patients with active #brainmetastases of various #tumour types. ☑️
A study led by #MedUniVienna shows that patritumab deruxtecan is effective in patients with #lungcancer & #breastcancer.
Details! ⬇️
📰 @thelancetoncol.bsky.social
A study led by #MedUniVienna shows that patritumab deruxtecan is effective in patients with #lungcancer & #breastcancer.
Details! ⬇️
📰 @thelancetoncol.bsky.social
🧠 New research reveals why #Immunotherapy often fails in symptomatic #BrainMetastases: some astrocytes block T-cell activity. By combining treatments, this local immunosuppression is no longer observed. A promising step towards personalized treatment! bit.ly/3IvfqLw
August 25, 2025 at 8:01 AM
🧠 New research reveals why #Immunotherapy often fails in symptomatic #BrainMetastases: some astrocytes block T-cell activity. By combining treatments, this local immunosuppression is no longer observed. A promising step towards personalized treatment! bit.ly/3IvfqLw
💡Explore the latest breakthroughs in #CNS #radiationoncology as presented at #ESTRO25 — from simulation-free planning and LET-guided dose sculpting to #adaptiveRT and next-gen imaging biomarkers.
👉 bit.ly/450oWxZLink
#CNSOncology #Radonc #NeuroOncology #BrainMetastases
👉 bit.ly/450oWxZLink
#CNSOncology #Radonc #NeuroOncology #BrainMetastases
July 21, 2025 at 7:51 AM
💡Explore the latest breakthroughs in #CNS #radiationoncology as presented at #ESTRO25 — from simulation-free planning and LET-guided dose sculpting to #adaptiveRT and next-gen imaging biomarkers.
👉 bit.ly/450oWxZLink
#CNSOncology #Radonc #NeuroOncology #BrainMetastases
👉 bit.ly/450oWxZLink
#CNSOncology #Radonc #NeuroOncology #BrainMetastases
Featured today by @MSKLibrary: Multi-institutional atlas of brain metastases informs spatial modeling for precision imaging and personalized therapy dx.doi.org/10.1038/s414...
#MultiInstitutionalResearch #BrainMetastases #PrecisionImaging #PersonalizedTherapy #NeuroOncology #CancerResearch
#MultiInstitutionalResearch #BrainMetastases #PrecisionImaging #PersonalizedTherapy #NeuroOncology #CancerResearch
June 6, 2025 at 4:40 PM
Featured today by @MSKLibrary: Multi-institutional atlas of brain metastases informs spatial modeling for precision imaging and personalized therapy dx.doi.org/10.1038/s414...
#MultiInstitutionalResearch #BrainMetastases #PrecisionImaging #PersonalizedTherapy #NeuroOncology #CancerResearch
#MultiInstitutionalResearch #BrainMetastases #PrecisionImaging #PersonalizedTherapy #NeuroOncology #CancerResearch
Recently published in npj Precision Oncology: Breast cancer brain metastases genomic profiling identifies alterations targetable by immune-checkpoint and PARP inhibitors. 👉 pubmed.ncbi.nlm.nih.gov/39706915/ (Open access) #EANOessentials #NeuroOncology #BrainMetastases #BreastCancer #btsm
Breast cancer brain metastases genomic profiling identifies alterations targetable by immune-checkpoint and PARP inhibitors - PubMed
Understanding the genomic landscape of breast cancer brain metastases (BCBMs) is key to developing targeted treatments. In this study, targetable genomic profiling was performed on 822 BCBMs, 11,988 l...
pubmed.ncbi.nlm.nih.gov
January 16, 2025 at 7:29 PM
Recently published in npj Precision Oncology: Breast cancer brain metastases genomic profiling identifies alterations targetable by immune-checkpoint and PARP inhibitors. 👉 pubmed.ncbi.nlm.nih.gov/39706915/ (Open access) #EANOessentials #NeuroOncology #BrainMetastases #BreastCancer #btsm
Just released: Joint EANM/EANO/RANO/SNMMI practice guideline/procedure standard for PET imaging of brain metastases: version 1.0 👉 link.springer.com/article/10.1... #EANOessentials #NeuroOncology #BrainMetastases #PET #btsm
January 8, 2025 at 11:59 AM
Just released: Joint EANM/EANO/RANO/SNMMI practice guideline/procedure standard for PET imaging of brain metastases: version 1.0 👉 link.springer.com/article/10.1... #EANOessentials #NeuroOncology #BrainMetastases #PET #btsm
#Sotorasib Is Not Effective in a #KRAS-Mutated Patient With #BrainMetastases From #LungAdenocarcinoma due to Multiple Gene Co-Mutations
onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com
May 19, 2025 at 3:00 AM
#Sotorasib Is Not Effective in a #KRAS-Mutated Patient With #BrainMetastases From #LungAdenocarcinoma due to Multiple Gene Co-Mutations
onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com/doi/10.1002/...
Very happy and honored to present our work on #brainmetastases networks at #SNO2024 plenary session this afternoon.
@winklerlab.bsky.social
@neuroonc.bsky.social
#cancerneuroscience
@winklerlab.bsky.social
@neuroonc.bsky.social
#cancerneuroscience
November 23, 2024 at 7:06 PM
Very happy and honored to present our work on #brainmetastases networks at #SNO2024 plenary session this afternoon.
@winklerlab.bsky.social
@neuroonc.bsky.social
#cancerneuroscience
@winklerlab.bsky.social
@neuroonc.bsky.social
#cancerneuroscience
A recent publication in Journal of Clinical Oncology covers stereotactic radiosurgery in small cell lung cancer patients with 1–10 brain metastases, from a multi-institutional phase II prospective trial.
🔗 ascopubs.org/doi/10.1200/...
#NeuroOncology #Glioma #BrainMetastases #EANOessentials #medsky
🔗 ascopubs.org/doi/10.1200/...
#NeuroOncology #Glioma #BrainMetastases #EANOessentials #medsky
Stereotactic Radiosurgery in Patients With Small Cell Lung Cancer and 1-10 Brain Metastases: A Multi-Institutional, Phase II, Prospective Clinical Trial
PURPOSEStereotactic radiation (SRS/SRT) as opposed to whole-brain radiation (WBRT) represents
the standard of care for patients with a limited number of brain metastases given
the relatively favorable...
ascopubs.org
July 21, 2025 at 11:10 AM
A recent publication in Journal of Clinical Oncology covers stereotactic radiosurgery in small cell lung cancer patients with 1–10 brain metastases, from a multi-institutional phase II prospective trial.
🔗 ascopubs.org/doi/10.1200/...
#NeuroOncology #Glioma #BrainMetastases #EANOessentials #medsky
🔗 ascopubs.org/doi/10.1200/...
#NeuroOncology #Glioma #BrainMetastases #EANOessentials #medsky
🎥 New on #OncologyBytes (IUCS 2024)
A rare prostate cancer case: Brain mets despite undetectable PSA.
Dr. Luciano Stumbo breaks it down — and why MRI matters.
📺 Watch: youtu.be/nFg2XbgkzrQ
🌐 More at: oncoassist.com
#IUCS2024 #ProstateCancer #BrainMetastases #Oncoassist #CancerCare #Oncoalert
A rare prostate cancer case: Brain mets despite undetectable PSA.
Dr. Luciano Stumbo breaks it down — and why MRI matters.
📺 Watch: youtu.be/nFg2XbgkzrQ
🌐 More at: oncoassist.com
#IUCS2024 #ProstateCancer #BrainMetastases #Oncoassist #CancerCare #Oncoalert
April 8, 2025 at 2:22 PM
🎥 New on #OncologyBytes (IUCS 2024)
A rare prostate cancer case: Brain mets despite undetectable PSA.
Dr. Luciano Stumbo breaks it down — and why MRI matters.
📺 Watch: youtu.be/nFg2XbgkzrQ
🌐 More at: oncoassist.com
#IUCS2024 #ProstateCancer #BrainMetastases #Oncoassist #CancerCare #Oncoalert
A rare prostate cancer case: Brain mets despite undetectable PSA.
Dr. Luciano Stumbo breaks it down — and why MRI matters.
📺 Watch: youtu.be/nFg2XbgkzrQ
🌐 More at: oncoassist.com
#IUCS2024 #ProstateCancer #BrainMetastases #Oncoassist #CancerCare #Oncoalert
If you are interested in #calciumimaging of #brainmetastases and cancer networks, come see my poster at #SNO2024 (CSIG-11) and listen to @nielsolshausen.bsky.social plenary talk tomorrow at 2:10pm! Happy to connect
November 22, 2024 at 8:12 PM
If you are interested in #calciumimaging of #brainmetastases and cancer networks, come see my poster at #SNO2024 (CSIG-11) and listen to @nielsolshausen.bsky.social plenary talk tomorrow at 2:10pm! Happy to connect
This research examines the single-cell and spatial genomic landscape of non-small cell lung cancer (#NSCLC) brain metastases. 🔗 Read the full article in Nature Medicine 👉 rdcu.be/eh8y7 #EANOessentials #NeuroOncology #BrainMetastases #btsm
Single-cell and spatial genomic landscape of non-small cell lung cancer brain metastases
Nature Medicine - Multi-omic single-cell and spatial analyses of lung cancer brain metastases from multiple cohorts identify high levels of chromosomal instability and a neural-like profile in...
rdcu.be
April 25, 2025 at 11:38 AM
This research examines the single-cell and spatial genomic landscape of non-small cell lung cancer (#NSCLC) brain metastases. 🔗 Read the full article in Nature Medicine 👉 rdcu.be/eh8y7 #EANOessentials #NeuroOncology #BrainMetastases #btsm
Nivolumab + relatlimab show promising intracranial activity in melanoma brain metastases! A beacon of hope for resistant cases and a call for more research!
#Melanoma #BrainMetastases #Immunotherapy #Nivolumab #Relatlimab #CheckpointInhibitors #TCSC #Oncology
www.cancernetwork.com/view/nivolum...
#Melanoma #BrainMetastases #Immunotherapy #Nivolumab #Relatlimab #CheckpointInhibitors #TCSC #Oncology
www.cancernetwork.com/view/nivolum...
Nivolumab/Relatlimab Elicit IC Activity in Anti–PD-L1–Refractory Melanoma Brain Mets
The combination elicited a clinical benefit rate of 63.0% and an overall response rate of 22.2% in anti–PD-L1–refractory melanoma with melanoma brain metastases.
www.cancernetwork.com
June 9, 2025 at 7:16 AM
Nivolumab + relatlimab show promising intracranial activity in melanoma brain metastases! A beacon of hope for resistant cases and a call for more research!
#Melanoma #BrainMetastases #Immunotherapy #Nivolumab #Relatlimab #CheckpointInhibitors #TCSC #Oncology
www.cancernetwork.com/view/nivolum...
#Melanoma #BrainMetastases #Immunotherapy #Nivolumab #Relatlimab #CheckpointInhibitors #TCSC #Oncology
www.cancernetwork.com/view/nivolum...
🧠 40% of patients with non-small cell #LungCancer suffer #BrainMetastases, and there are few therapies.
🔬 Researchers from McMaster University found that a protein linked to #AlzheimersDisease helps cancer spread to the brain in #mice.
🔗 eara.eu/post/protein...
#CancerResearch #DrugRepurposing
🔬 Researchers from McMaster University found that a protein linked to #AlzheimersDisease helps cancer spread to the brain in #mice.
🔗 eara.eu/post/protein...
#CancerResearch #DrugRepurposing
Protein helps lung cancer reach the brain in mice
Researchers from Canada have discovered that a protein long connected to Alzheimer’s disease helps lung cancer cells in mice spread to the brain.
www.eara.eu
July 15, 2025 at 10:01 AM
🧠 40% of patients with non-small cell #LungCancer suffer #BrainMetastases, and there are few therapies.
🔬 Researchers from McMaster University found that a protein linked to #AlzheimersDisease helps cancer spread to the brain in #mice.
🔗 eara.eu/post/protein...
#CancerResearch #DrugRepurposing
🔬 Researchers from McMaster University found that a protein linked to #AlzheimersDisease helps cancer spread to the brain in #mice.
🔗 eara.eu/post/protein...
#CancerResearch #DrugRepurposing
🔬 New research by @valientelab.bsky.social et al., published in Cancer Discovery, reveals how #brainmetastases adapt to evade targeted therapies. These findings point to molecular vulnerabilities that could help overcome therapeutic resistance.
Next Directions in the Neuroscience of Cancers Arising outside the CNS - PubMed
The field of cancer neuroscience has begun to define the contributions of nerves to cancer initiation and progression; here, we highlight the future directions of basic and translational cancer…
buff.ly
January 28, 2025 at 9:00 AM
🔬 New research by @valientelab.bsky.social et al., published in Cancer Discovery, reveals how #brainmetastases adapt to evade targeted therapies. These findings point to molecular vulnerabilities that could help overcome therapeutic resistance.
A recent publication in ESMO Open covers the intracranial activity of T-DXd in HER2-positive breast cancer with brain metastases. Find out more 👉 www.esmoopen.com/article/S205... #EANOessentials #NeuroOncology #BrainMetastases #BreastCancer
Results of a patient-level pooled analysis of three studies of trastuzumab deruxtecan in HER2-positive breast cancer with active brain metastasis
Brain metastases (BMs) are common in human epidermal growth factor receptor 2 (HER2)-positive
advanced breast cancer, increasing morbidity and mortality. Systemic therapy for BMs
can be effective, wit...
www.esmoopen.com
January 24, 2025 at 5:13 PM
A recent publication in ESMO Open covers the intracranial activity of T-DXd in HER2-positive breast cancer with brain metastases. Find out more 👉 www.esmoopen.com/article/S205... #EANOessentials #NeuroOncology #BrainMetastases #BreastCancer
How do #metastases survive (and thrive!) in the #brain microenvironment?
In our review, now online @cp-neuron.bsky.social, we discuss the recent findings on #cancerneuroscience of #brainmetastases:
Learn all about how #cancer cells adapt to, and communicate with, this unique environment 🧠
In our review, now online @cp-neuron.bsky.social, we discuss the recent findings on #cancerneuroscience of #brainmetastases:
Learn all about how #cancer cells adapt to, and communicate with, this unique environment 🧠
September 4, 2025 at 5:41 AM
How do #metastases survive (and thrive!) in the #brain microenvironment?
In our review, now online @cp-neuron.bsky.social, we discuss the recent findings on #cancerneuroscience of #brainmetastases:
Learn all about how #cancer cells adapt to, and communicate with, this unique environment 🧠
In our review, now online @cp-neuron.bsky.social, we discuss the recent findings on #cancerneuroscience of #brainmetastases:
Learn all about how #cancer cells adapt to, and communicate with, this unique environment 🧠
Recently published in @cellpress.bsky.social: Microglial reprogramming enhances antitumor immunity and immunotherapy response in melanoma brain metastases 👉 bit.ly/3XmWyD8
#EANOessentials #BrainMetastases #NeuroOncology
#EANOessentials #BrainMetastases #NeuroOncology
March 1, 2025 at 9:32 AM
Recently published in @cellpress.bsky.social: Microglial reprogramming enhances antitumor immunity and immunotherapy response in melanoma brain metastases 👉 bit.ly/3XmWyD8
#EANOessentials #BrainMetastases #NeuroOncology
#EANOessentials #BrainMetastases #NeuroOncology
#Medsky🧪 #immunosky #oncosky #neurosky Up to 20 % of metastatic 🧠 tumors arise from primary BC www.nature.com/articles/s41... While primary #breastcancer is curable if caught early, metastatic tumors have significantly poorer survival rates. #Brainmetastases,
Brain metastases
Nature Reviews Disease Primers - An estimated 20% of all patients with cancer will develop brain metastases, with the majority of brain metastases occurring in those with lung and breast cancer and...
www.nature.com
May 18, 2025 at 5:11 PM
#Medsky🧪 #immunosky #oncosky #neurosky Up to 20 % of metastatic 🧠 tumors arise from primary BC www.nature.com/articles/s41... While primary #breastcancer is curable if caught early, metastatic tumors have significantly poorer survival rates. #Brainmetastases,
👉 Recently published in Clinical Cancer Research: A population-level real-world analysis and single-center validation of melanoma brain metastasis epidemiology following dual-agent immunotherapy 🔗 doi.org/10.1158/1078... #EANOessentials #NeuroOncology #BrainMetastases #brainMets #medsky
July 11, 2025 at 8:18 AM
👉 Recently published in Clinical Cancer Research: A population-level real-world analysis and single-center validation of melanoma brain metastasis epidemiology following dual-agent immunotherapy 🔗 doi.org/10.1158/1078... #EANOessentials #NeuroOncology #BrainMetastases #brainMets #medsky
Presurgical Radiation Therapy May Offer Alternative Approach to Treating Brain Metastases
@mdanderson.bsky.social #BrainMetastases
www.onclive.com/view/presurg...
@mdanderson.bsky.social #BrainMetastases
www.onclive.com/view/presurg...
Presurgical Radiation Therapy May Offer Alternative Approach to Treating Brain Metastases
Studies have suggested that pre-surgical SRT may be comparable to standard post-surgical SRT in patients with resectable brain metastases.
www.onclive.com
June 27, 2025 at 5:06 PM
Presurgical Radiation Therapy May Offer Alternative Approach to Treating Brain Metastases
@mdanderson.bsky.social #BrainMetastases
www.onclive.com/view/presurg...
@mdanderson.bsky.social #BrainMetastases
www.onclive.com/view/presurg...
👉 An article discussing nerve-to-cancer transfer of mitochondria during cancer metastasis is now available in @nature.com 🔗 www.nature.com/articles/s41... #CancerResearch #BrainMetastases #NeuroOncology #EANOessentials #Nature #medsky
Nerve-to-cancer transfer of mitochondria during cancer metastasis - Nature
A study reports the development of a method to trace intercellular transfer of mitochondria, and demonstrates that cancer cells that receive mitochondria from neurons have enhanced metastatic capabili...
www.nature.com
August 4, 2025 at 3:15 PM
👉 An article discussing nerve-to-cancer transfer of mitochondria during cancer metastasis is now available in @nature.com 🔗 www.nature.com/articles/s41... #CancerResearch #BrainMetastases #NeuroOncology #EANOessentials #Nature #medsky
🔬🧪 Using single-cell & bulk RNA sequencing, integrated with spatial analyses, we built a vascular and immune #atlas of brain tumors
🧠 GBMs have restricted immune infiltration, while BrMs have a more permeable vasculature and interact extensively with immune cells
#Glioblastoma #BrainMetastases
2/
🧠 GBMs have restricted immune infiltration, while BrMs have a more permeable vasculature and interact extensively with immune cells
#Glioblastoma #BrainMetastases
2/
March 20, 2025 at 1:52 PM
🔬🧪 Using single-cell & bulk RNA sequencing, integrated with spatial analyses, we built a vascular and immune #atlas of brain tumors
🧠 GBMs have restricted immune infiltration, while BrMs have a more permeable vasculature and interact extensively with immune cells
#Glioblastoma #BrainMetastases
2/
🧠 GBMs have restricted immune infiltration, while BrMs have a more permeable vasculature and interact extensively with immune cells
#Glioblastoma #BrainMetastases
2/
Online First: 7-year follow-up of the ABC study:
#Ipilimumab plus #nivolumab versus nivolumab alone in patients with #melanoma #brainmetastases: a multicentre, open-label, randomised, phase 2 study
https://buff.ly/3X44fOt
#Ipilimumab plus #nivolumab versus nivolumab alone in patients with #melanoma #brainmetastases: a multicentre, open-label, randomised, phase 2 study
https://buff.ly/3X44fOt
February 18, 2025 at 11:14 AM
Online First: 7-year follow-up of the ABC study:
#Ipilimumab plus #nivolumab versus nivolumab alone in patients with #melanoma #brainmetastases: a multicentre, open-label, randomised, phase 2 study
https://buff.ly/3X44fOt
#Ipilimumab plus #nivolumab versus nivolumab alone in patients with #melanoma #brainmetastases: a multicentre, open-label, randomised, phase 2 study
https://buff.ly/3X44fOt
#BrainMetastases (BM) from #PancreaticCancer are rare. However, in 41% of cases, BM was the first sign of spread. Early neuroimaging in high-risk patients may enable earlier diagnosis and improve outcomes.
#Oncology #PrecisionOncology #ClinicalOncology #NeuroOncology #MetastaticCancer
#Oncology #PrecisionOncology #ClinicalOncology #NeuroOncology #MetastaticCancer
June 9, 2025 at 1:17 PM
#BrainMetastases (BM) from #PancreaticCancer are rare. However, in 41% of cases, BM was the first sign of spread. Early neuroimaging in high-risk patients may enable earlier diagnosis and improve outcomes.
#Oncology #PrecisionOncology #ClinicalOncology #NeuroOncology #MetastaticCancer
#Oncology #PrecisionOncology #ClinicalOncology #NeuroOncology #MetastaticCancer