#AploScope
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Understand biological context with #AploScope: study #tissues and #cells across scales all the way down to single molecules. Perform fast #multicolor imaging within one sample and easily generate meaningful multicolor panels 🌈✨
Read our App note: tinyurl.com/57ss8s6s
#SuperResolution #microscopy
April 9, 2025 at 9:21 AM
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Navigate your sample across scales with #AploScope: from low-power #LiveCell to high-power #SuperResolution imaging at 15 nm resolution, no need for reconfiguration. Explore biological context with multimodal imaging and easily obtain 5 color panels! 🌈 t.co/q6R1XWjec5
March 6, 2025 at 10:34 AM
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Thank you to Genetic Engineering & Biotechnology News for recognizing Aplo Scope for the New Product Innovation Spotlight! 🔬

lnkd.in/e7JcuHTU

#Innovation #Biotech #Microscopy #SuperResolution #AploScope #TechInBio
A computer screen showing the front of the article from Genetic Engineering & Biotechnology News.
February 3, 2025 at 8:37 PM
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It's #FluorescenceFriday and we are happy to share a 5-color image taken with the #AploScope. Here we have a #SuperResolution #SMLM (#SingleMolecule Localization #Microscopy) image of the mitochondrial protein #Tomm20 in yellow, and the following diffraction-limited targets:
A 5-color image taken with ONI's Aplo Scope. The labelling includes mitochondria Tomm20 in yellow, lysosome Lamp1 in red, nucelus Hoechst in blue, cytoskeleton tubulin in cyan and plasma membrane CellMask in gray.
March 21, 2025 at 10:52 AM
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We understand that #ScientificProjects are often complexed and unpredictable. Your #SuperResolution #SMLM experiments don't have to be. Our new #AploScope combines high performance and ease-of-use in a single, versatile #microscope, Simplicity without compromise
April 3, 2025 at 8:46 AM
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We are so proud to support the first ever in-person meeting of #CanSEV, the Canadian Society for #ExtraCellularVesicles! Find us at the The Neuro, Montreal, May 20-21 2025 and check out our latest offers in EV research!
#CanSEV2025 #EVProfiler2 #AutoEV #Nanoimager #AploScope #dSTORM #SuperResolution
ONI is attending CanSEV, the first in-person meeting of the Canadian Society for Extracellular Vesicles
May 12, 2025 at 9:27 AM
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#AploScope lets you to choose your #illumination angle based on your experimental needs. In #TIRF, the laser is directed at the sample at a very sharp angle, so that only fluorophores at a very thin layer of the sample are excited, offering excellent #SignalToNoise ratio.
hubs.li/Q034lXRT0
Animation of Aplo Scope's illumination angles.
January 29, 2025 at 9:06 AM
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ONI's #AploScope has a comprehensive set of lasers and filters, engineered to enable multicolor imaging.
Read our latest Application Note on cell biology research with 5-color imaging to get inspiration for how you could apply these approaches in your research.
hubs.li/Q03258T-0 #SMLM #microscopy
U2OS cells stained with 5 different colors, labelling the nucleus, mitochondria, clathrin vesicles, tubulin and lysosomes.
January 14, 2025 at 9:31 AM
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🔬🌟 Find us at the 25th international meeting of the European Light Microscopy Initiative ( #ELMI ), 3-6 June 2025, Heidelberg, Germany! #ELMI2025 here we come! 🌟🔬
#SuperResolution #microscopy #SMLM #Nanoimager #AploScope #Fluorescence #SingleMolecule #LifeSciences #dSTORM #Immunofluorescence
ONI team will be at ELMI 2025 meeting in Heidelberg, 3-6 June 2025.
May 6, 2025 at 10:42 AM
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Did you miss our #AploScope #webinar yesterday? Watch it here ➡️ hubs.li/Q034R6QZ0..
Let our team walk you through the ins-and-outs of Aplo Scope and the #CODI software platform, as well as its capabilities in #CellBiology, #DrugScreens and #DiseaseResearch.
Details of ONI’s webinar whose link is attached
January 31, 2025 at 12:11 PM
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Experience #AploScope through our virtual demo video! 🎥🔬
With advanced #imaging, precise laser control, and intuitive software, Aplo Scope delivers high-quality results. Its compact design allows for easy #SuperResolution imaging, all without complex setup.

Watch now 🎥 lnkd.in/enp34z2U
February 27, 2025 at 10:25 AM
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It's #FluorescenceFriday and this week we are sharing a beautiful 5-color image taken by ONI's senior scientists Dr Stefan Balint using our #AploScope. In this image, we have 2 detailed #dSTORM channels, showing the mitochondrial protein #Tomm20 and the lysosomal protein #LAMP1.
Microscopy image taken with ONI's Aplo Scope. The image is composed of 5 different colors showing 5 different targets: mitochondria and lysosomes in dSTORM and the plasma membrane, the cytoskeleton and the nucleus in diffraction-limited imaging. Each target is shown separately next to an overlay of all targets.
January 31, 2025 at 9:14 AM
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#CanSEV, the Canadian Society for #ExtraCellularVesicles starts today! Find us at the The Neuro, Montreal, and check out our latest offers in EV research!

#CanSEV2025, #EVProfiler2 #AutoEV #Nanoimager #AploScope #dSTORM #SMLM #SuperResolution #ExtraCellularVesicles
May 20, 2025 at 8:57 AM
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Read the full paper: hubs.li/Q033xT7G0

Want to learn more about preparing tissue samples for SMLM? Read our new Technical Guide: hubs.li/Q033xSMf0

#microscopy #microscope #AploScope #DrugDiscovery #Diagnostics #TranslationalResearch #Research #MedicalResearch #Pathology #Histology #Histopathology
Single-molecule localisation microscopy (SMLM) is feasible in human and animal formalin fixed paraffin embedded (FFPE) tissues in medical renal disease
Aims Establishment of a protocol for routine single-molecule localisation microscopy (SMLM) imaging on formalin fixed paraffin embedded (FFPE) tissue using medical renal disease including minimal chan...
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January 24, 2025 at 8:26 AM
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🌟 We are very excited about our new #AploScope and we cannot wait to share the excitement with all of you! 🔬

🚀 Ready for a demo? Why don't you join our Aplo Scope Demo Day in our Oxford office on the 29th of January? sign up and secure your place ➡️ hubs.li/Q0323nb40
Banner for the Aplo Scope Demo Day in ONI's Oxford office, 29th of January 2025, 1 PM - 5 PM.
January 13, 2025 at 9:53 AM
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#AploScope is designed to be a high #throughput #microscope, with a FOV of 110 by 110 micrometers in both diffraction-limited and #SMLM. Capture cell populations, unique biomarkers or elusive phenotypes with ease
Start your super-resolution journey at t.co/mkfy4dLhCh t.co/1miJmNYVM3
April 30, 2025 at 8:42 AM
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Our Oxford team enjoyed their annual springtime crafts day with #microscopy -inspired paintings. Most focused on #LipidNanoParticles and #CellBiology, some inspired by #AploScope and some were more abstract. We loved the #TeamBuilding activity and we are already looking forward to our next session!
April 7, 2025 at 12:52 PM
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ONI’s #AploScope #SuperResolution #microscope has been engineered for reliability and maximal performance. Its powerful imaging capabilities and integrated software help ensure reproducibility across experiments and users. Discover the power of Aplo! oni.bio/aploscope #microscopy #SMLM #dSTORM
May 7, 2025 at 9:13 AM
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Are you new to #SuperResolution? Forget about intricate #microscopy settings, #AploScope and #CODI #software do it for you!
If you are a power user, manual tuning options are available too! Maximize outcomes that make breakthrough discovery possible 🚀http://oni.bio/aploscope
March 17, 2025 at 11:09 AM
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Master multicolor #imaging with #AploScope! ONI’s benchtop #SuperResolution #microscope designed for optimal spectral separation between fluorophores with custom emission filters. Generate beautiful 5 color multimodal images! 🌈
▶️Watch now t.co/vxXued2K0P t.co/wO7wwGSJXE
May 20, 2025 at 1:46 PM
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🌟 Join us on January 30, 2025 for an exclusive look at the #AploScope, ONI's new #SuperResolution #microscope. We will introduce Aplo Scope and its transformative features, as well as our new software tools to control the microscope and analyze the data. Register now 👉 hubs.li/Q0336bvM0%F0...
Advertising ONI's webinar on Aplo Scope on the 30th of January 2025.
January 22, 2025 at 5:59 PM
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ONI had the pleasure of supporting the UCL Symposium on #ExtraCellularVesicles 2025. This was our first meeting after launching #AploScope, our latest #innovative #SuperResolution #Microscope, so we were excited to showcase it to everyone.

Thank you, @ucl.ac.uk for inviting us!
Dr Pip Timmins describes the advantages of Aplo Scope in UCL's Extracellular Vesicles Community meeting. Dr Pip Timmins describes the advantages of Aplo Scope in UCL's Extracellular Vesicles Community meeting. Networking and Nibbles time at the UCL's Extracellular Vesicles Community meeting. Networking and Nibbles time at the UCL's Extracellular Vesicles Community meeting.
January 13, 2025 at 12:19 PM
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ONI's #AploScope and #Nanoimager support multiple SMLM modalities, examples for which can be found in dozens of high-quality peer-review publications.

Want to know which SMLM technique is right for you? watch our webinar: hubs.li/Q034G08Q0
How to Choose Your Super Resolution Technique
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January 30, 2025 at 9:39 AM
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We believe that #SuperResolution #microscopy belongs in any lab, allowing any scientist to observe the nanoscale details of life. With #AploScope it is now easier to get started with super-resolution. Simply unpack the instrument and start imaging! No dark room or special calibrations needed.
March 12, 2025 at 11:55 AM
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🔬 #TellTheOrganelle #AploScope edition! 🔬

Our scientists took this beautiful #SMLM #SuperResolution image of which two mammalian cellular organelles? share your answers in the comments!
SMLM of two mammalian organelles in a U2OS cells, labelled in cyan and magenta.
March 18, 2025 at 11:43 AM