Etkileşim kaynağı, 15.000'den fazla protein için ağları ve AlphaFold3 modellemesine dayalı 23.000 tahmini protein-protein etkileşim yapısını içerir.
November 11, 2025 at 3:46 PM
Etkileşim kaynağı, 15.000'den fazla protein için ağları ve AlphaFold3 modellemesine dayalı 23.000 tahmini protein-protein etkileşim yapısını içerir.
Durante el workshop aprenderás a:
🔹 Analizar estructuras de proteínas con #ChimeraX
🔹 Predecir modelos con #AlphaFold3
🔹 Diseñar proteínas artificiales (de novo protein binders)
🔹 Entender cómo la #IA transforma la biología estructural
🔹 Analizar estructuras de proteínas con #ChimeraX
🔹 Predecir modelos con #AlphaFold3
🔹 Diseñar proteínas artificiales (de novo protein binders)
🔹 Entender cómo la #IA transforma la biología estructural
November 11, 2025 at 1:53 PM
Durante el workshop aprenderás a:
🔹 Analizar estructuras de proteínas con #ChimeraX
🔹 Predecir modelos con #AlphaFold3
🔹 Diseñar proteínas artificiales (de novo protein binders)
🔹 Entender cómo la #IA transforma la biología estructural
🔹 Analizar estructuras de proteínas con #ChimeraX
🔹 Predecir modelos con #AlphaFold3
🔹 Diseñar proteínas artificiales (de novo protein binders)
🔹 Entender cómo la #IA transforma la biología estructural
Este taller te guiará desde los fundamentos de la estructura de proteínas hasta las herramientas modernas de predicción y diseño, con foco en #AlphaFold3 —la tecnología galardonada con el Premio Nobel de Química 2024
November 11, 2025 at 1:53 PM
Este taller te guiará desde los fundamentos de la estructura de proteínas hasta las herramientas modernas de predicción y diseño, con foco en #AlphaFold3 —la tecnología galardonada con el Premio Nobel de Química 2024
Just made a cover for a fresh study from @rociomer.bsky.social 's team where AlphaFold3 and Boltz‑1 tackle PROTAC ternary complex prediction!
Great news for targeted protein degradation!
#sciart ⌬ #research ⌬ #chemistry
Great news for targeted protein degradation!
#sciart ⌬ #research ⌬ #chemistry
November 10, 2025 at 3:57 PM
Just made a cover for a fresh study from @rociomer.bsky.social 's team where AlphaFold3 and Boltz‑1 tackle PROTAC ternary complex prediction!
Great news for targeted protein degradation!
#sciart ⌬ #research ⌬ #chemistry
Great news for targeted protein degradation!
#sciart ⌬ #research ⌬ #chemistry
High-accuracy structure modeling for antibody-antigen complexes [new]
Leverages AlphaFold3, enhancing static data with dynamic interactions via a flexibility-aware energy function for improved antibody-antigen modeling.
Leverages AlphaFold3, enhancing static data with dynamic interactions via a flexibility-aware energy function for improved antibody-antigen modeling.
November 4, 2025 at 8:11 PM
High-accuracy structure modeling for antibody-antigen complexes [new]
Leverages AlphaFold3, enhancing static data with dynamic interactions via a flexibility-aware energy function for improved antibody-antigen modeling.
Leverages AlphaFold3, enhancing static data with dynamic interactions via a flexibility-aware energy function for improved antibody-antigen modeling.
cytochrome_and_heme protein ligand complex visualization from alphafold3 predicted output
November 3, 2025 at 5:43 AM
cytochrome_and_heme protein ligand complex visualization from alphafold3 predicted output
#Google is going to win the #AI race, as they are a real company. #SRL is a new twist on #AI learning. They quietly release killer apps like #NotebookLM, #AlphaFold3, #Jules, and have #DeepMind to work out hard frontier issues.
Long term, bet on Google.
#AI #TrueIntelligence
youtu.be/ANICPVqJ2ps?...
Long term, bet on Google.
#AI #TrueIntelligence
youtu.be/ANICPVqJ2ps?...
Google Just Achieved True Intelligence With New AI
YouTube video by AI Revolution
youtu.be
November 3, 2025 at 12:49 AM
#Google is going to win the #AI race, as they are a real company. #SRL is a new twist on #AI learning. They quietly release killer apps like #NotebookLM, #AlphaFold3, #Jules, and have #DeepMind to work out hard frontier issues.
Long term, bet on Google.
#AI #TrueIntelligence
youtu.be/ANICPVqJ2ps?...
Long term, bet on Google.
#AI #TrueIntelligence
youtu.be/ANICPVqJ2ps?...
Multimodal deep learning integration of cryo-EM and AlphaFold3 for high-accuracy protein structure determination pubmed.ncbi.nlm.nih.gov/41174029/ #cryoem
November 3, 2025 at 12:16 AM
Multimodal deep learning integration of cryo-EM and AlphaFold3 for high-accuracy protein structure determination pubmed.ncbi.nlm.nih.gov/41174029/ #cryoem
An open-source AI model called OpenFold3 is a recreation of AlphaFold3. It predicts how proteins interact with drugs and other molecules, perhaps speeding drug discovery.
https://www.sciencenews.org/article/ai-model-openfold3-protein-predictions
https://www.sciencenews.org/article/ai-model-openfold3-protein-predictions
The AI model OpenFold3 takes a crucial step in making protein predictions
The open-source AI model improves transparency in predicting how proteins interact with other molecules, which could speed up drug discovery.
www.sciencenews.org
November 1, 2025 at 3:50 PM
An open-source AI model called OpenFold3 is a recreation of AlphaFold3. It predicts how proteins interact with drugs and other molecules, perhaps speeding drug discovery.
https://www.sciencenews.org/article/ai-model-openfold3-protein-predictions
https://www.sciencenews.org/article/ai-model-openfold3-protein-predictions
AlphaFold3のオープンソース版としてOpenFold3というのが先行リリースされるという記事。企業の人でも使えそうなので、これは興味深い
www.nature.com/articles/d41...
www.nature.com/articles/d41...
Open-source protein structure AI aims to match AlphaFold
The developers of OpenFold3 have released an early version of the tool, which they hope will one day perform on par with DeepMind’s protein-structure model.
www.nature.com
November 1, 2025 at 12:33 PM
AlphaFold3のオープンソース版としてOpenFold3というのが先行リリースされるという記事。企業の人でも使えそうなので、これは興味深い
www.nature.com/articles/d41...
www.nature.com/articles/d41...
🧶🧬 We present LMi4Boltz:
www.biorxiv.org/content/10.1...
Boltz-2 is an excellent open source alternative to AlphaFold3. However, high VRAM use restricts modeling large complexes. Using careful memory management, we increase the Boltz-2 size limit by >60% while maintaining execution speed.
www.biorxiv.org/content/10.1...
Boltz-2 is an excellent open source alternative to AlphaFold3. However, high VRAM use restricts modeling large complexes. Using careful memory management, we increase the Boltz-2 size limit by >60% while maintaining execution speed.
October 31, 2025 at 8:54 PM
🧶🧬 We present LMi4Boltz:
www.biorxiv.org/content/10.1...
Boltz-2 is an excellent open source alternative to AlphaFold3. However, high VRAM use restricts modeling large complexes. Using careful memory management, we increase the Boltz-2 size limit by >60% while maintaining execution speed.
www.biorxiv.org/content/10.1...
Boltz-2 is an excellent open source alternative to AlphaFold3. However, high VRAM use restricts modeling large complexes. Using careful memory management, we increase the Boltz-2 size limit by >60% while maintaining execution speed.
Just out: Multimodal deep learning integration of cryo-EM and AlphaFold3 for high-accuracy protein structure determination
Multimodal deep learning integration of cryo-EM and AlphaFold3 for high-accuracy protein structure determination
Communications Chemistry, Published online: 31 October 2025; doi:10.1038/s42004-025-01718-5Cryo-electron microscopy (cryo-EM) is a key technology for elucidating protein structures, yet automating high-accuracy structure building from cryo-EM maps remains challenging. Here, the authors present MICA, a deep learning approach integrating cryo-EM data with AlphaFold3 predictions, achieving superior accuracy and robustness, thus advancing automated protein structure determination.
bit.ly
October 31, 2025 at 6:00 PM
Just out: Multimodal deep learning integration of cryo-EM and AlphaFold3 for high-accuracy protein structure determination
A new AI model is opening the black box of the leading artificial intelligence tool for predicting how proteins will interact with small molecules, such as drugs. The model, OpenFold3, which launched October 28, is a reconstruction of Google DeepMind’s AlphaFold3.
The AI model OpenFold3 takes a crucial step in making protein predictions
The open-source AI model improves transparency in predicting how proteins interact with other molecules, which could speed up drug discovery.
www.sciencenews.org
October 30, 2025 at 1:13 AM
A new AI model is opening the black box of the leading artificial intelligence tool for predicting how proteins will interact with small molecules, such as drugs. The model, OpenFold3, which launched October 28, is a reconstruction of Google DeepMind’s AlphaFold3.
Scientists today released a ‘sneak preview’ of a new open-source artificial intelligence (AI) model that predicts 3D structures of proteins, and say it is close to matching the performance of Google DeepMind’s revolutionary protein-folding AI AlphaFold3.
www.nature.com/articles/d41...
www.nature.com/articles/d41...
Open-source protein structure AI aims to match AlphaFold
The developers of OpenFold3 have released an early version of the tool, which they hope will one day perform on par with DeepMind’s protein-structure model.
www.nature.com
October 30, 2025 at 12:21 AM
Scientists today released a ‘sneak preview’ of a new open-source artificial intelligence (AI) model that predicts 3D structures of proteins, and say it is close to matching the performance of Google DeepMind’s revolutionary protein-folding AI AlphaFold3.
www.nature.com/articles/d41...
www.nature.com/articles/d41...
A new open-source protein structure AI, OpenFold3, aims for parity with AlphaFold3. The OpenFold Consortium has released a preview, inviting feedback. This model is fully open for both academic and commercial use, unlike its competitor. 🧬💻
Open-source protein structure AI aims to match AlphaFold
The developers of OpenFold3 have released an early version of the tool, which they hope will one day perform on par with DeepMind’s protein-structure model.
www.nature.com
October 29, 2025 at 4:15 PM
A new open-source protein structure AI, OpenFold3, aims for parity with AlphaFold3. The OpenFold Consortium has released a preview, inviting feedback. This model is fully open for both academic and commercial use, unlike its competitor. 🧬💻
OpenFold3 Challenges AlphaFold3 in Protein Folding
https://www.byteseu.com/1494026/
A new open-source AI model, OpenFold3, is poised to rival Google DeepMind's AlphaFold3 in predicting 3D protein structures. https://techlife.blog/posts/openfold3-ai-model/
https://www.byteseu.com/1494026/
A new open-source AI model, OpenFold3, is poised to rival Google DeepMind's AlphaFold3 in predicting 3D protein structures. https://techlife.blog/posts/openfold3-ai-model/
OpenFold3 Challenges AlphaFold3 in Protein Folding - Bytes Europe
A new open-source AI model, OpenFold3, is poised to rival Google DeepMind's AlphaFold3 in predicting 3D protein structures.
www.byteseu.com
October 29, 2025 at 2:13 PM
OpenFold3 Challenges AlphaFold3 in Protein Folding
https://www.byteseu.com/1494026/
A new open-source AI model, OpenFold3, is poised to rival Google DeepMind's AlphaFold3 in predicting 3D protein structures. https://techlife.blog/posts/openfold3-ai-model/
https://www.byteseu.com/1494026/
A new open-source AI model, OpenFold3, is poised to rival Google DeepMind's AlphaFold3 in predicting 3D protein structures. https://techlife.blog/posts/openfold3-ai-model/
Beating Alphafold3
genesis.ml/news/introdu...
genesis.ml/news/introdu...
Introducing Pearl: The Next Generation Foundation Model for Drug Discovery - Genesis Molecular AI
First Model to Clearly Surpass AlphaFold 3 on Protein-Ligand Structure Prediction Your browser does not support the video tag. Why is Structure Prediction a ‘Holy Grail’ Problem for Drug Discovery?...
genesis.ml
October 28, 2025 at 11:23 PM
Beating Alphafold3
genesis.ml/news/introdu...
genesis.ml/news/introdu...
Scientists today released a ‘sneak preview’ of a new open-source artificial intelligence (AI) model that predicts 3D structures of proteins, and say it is close to matching the performance of Google DeepMind’s revolutionary protein-folding AI AlphaFold3. www.nature.com/articles/d41... #biotech #AI
Open-source protein structure AI aims to match AlphaFold
The developers of OpenFold3 have released an early version of the tool, which they hope will one day perform on par with DeepMind’s protein-structure model.
www.nature.com
October 28, 2025 at 8:07 PM
Scientists today released a ‘sneak preview’ of a new open-source artificial intelligence (AI) model that predicts 3D structures of proteins, and say it is close to matching the performance of Google DeepMind’s revolutionary protein-folding AI AlphaFold3. www.nature.com/articles/d41... #biotech #AI
Looks like OpenFold3 has been formally released in a public "preview". Not quite on parity with AlphaFold3 on a few benchmarks shown, in particular for antibody interactions. All info on the github link. I am sure we will hear more about this from the developers github.com/aqlaboratory...
GitHub - aqlaboratory/openfold-3: OpenFold3: A fully open source biomolecular structure prediction model based on AlphaFold3
OpenFold3: A fully open source biomolecular structure prediction model based on AlphaFold3 - aqlaboratory/openfold-3
github.com
October 28, 2025 at 9:30 AM
Looks like OpenFold3 has been formally released in a public "preview". Not quite on parity with AlphaFold3 on a few benchmarks shown, in particular for antibody interactions. All info on the github link. I am sure we will hear more about this from the developers github.com/aqlaboratory...
AlphaFold3 co-structure predictions were also consistent with entry when this single mutation was introduced, revealing the likely molecular interaction that enables hACE2 compatibility.
October 28, 2025 at 5:07 AM
AlphaFold3 co-structure predictions were also consistent with entry when this single mutation was introduced, revealing the likely molecular interaction that enables hACE2 compatibility.
Impressively, AlphaFold3 predictions of RBD-ACE2 pairs were very consistent with pseudovirus results! RBDs with ACE2 entry had consistent binding footprints while RBDs without entry were predicted to bind inaccessible parts of the ACE2s.
October 28, 2025 at 5:07 AM
Impressively, AlphaFold3 predictions of RBD-ACE2 pairs were very consistent with pseudovirus results! RBDs with ACE2 entry had consistent binding footprints while RBDs without entry were predicted to bind inaccessible parts of the ACE2s.
@rohanpaul_ai https://x.com/rohanpaul_ai/status/1982952288470573310 #x-rohanpaul_ai
💊 Google's AlphaFold3 is so powerful and already accelerating drug discovery process.
A research team used AlphaFold3 and built a computer designed peptide gel that grows a patient's uterine cancer ...
💊 Google's AlphaFold3 is so powerful and already accelerating drug discovery process.
A research team used AlphaFold3 and built a computer designed peptide gel that grows a patient's uterine cancer ...
October 27, 2025 at 11:45 PM
@rohanpaul_ai https://x.com/rohanpaul_ai/status/1982952288470573310 #x-rohanpaul_ai
💊 Google's AlphaFold3 is so powerful and already accelerating drug discovery process.
A research team used AlphaFold3 and built a computer designed peptide gel that grows a patient's uterine cancer ...
💊 Google's AlphaFold3 is so powerful and already accelerating drug discovery process.
A research team used AlphaFold3 and built a computer designed peptide gel that grows a patient's uterine cancer ...
Predicting protein complexes in biosynthetic gene clusters [new]
Fast protein complex prediction in BGCs w/ AlphaFold3 boosts interaction insights & validation.
Fast protein complex prediction in BGCs w/ AlphaFold3 boosts interaction insights & validation.
October 27, 2025 at 8:06 PM
Predicting protein complexes in biosynthetic gene clusters [new]
Fast protein complex prediction in BGCs w/ AlphaFold3 boosts interaction insights & validation.
Fast protein complex prediction in BGCs w/ AlphaFold3 boosts interaction insights & validation.
Super cool talk from @kmichie.bsky.social. Lots of examples of how AlphaFold3 does weird stuff
October 27, 2025 at 2:14 AM
Super cool talk from @kmichie.bsky.social. Lots of examples of how AlphaFold3 does weird stuff
Preprint: Experiment-guided AlphaFold3 resolves accurate protein ensembles www.biorxiv.org/content/10.1...
Experiment-guided AlphaFold3 resolves accurate protein ensembles
AlphaFold3 predicts highly accurate protein structures from sequence, but tends to collapse to a single dominant conformation, even when the underlying structure is inherently heterogeneous. Moreover,...
www.biorxiv.org
October 23, 2025 at 3:39 PM
Preprint: Experiment-guided AlphaFold3 resolves accurate protein ensembles www.biorxiv.org/content/10.1...