PİRHA-  PSAKD Altınova Şube Başkanı Adnan Arslan, İstanbul Büyükşehir Belediyesi (İBB) Başkanı Ekrem İmamoğlu’nun cumhurbaşkanı adayı olarak sahada karşılık bulmasının sonucu olarak siyasi bir kararla...

At the 2025 ARSL Conference in Albuquerque, BMI Imaging Systems showcased their digital solutions aimed at aiding rural and small libraries, focusing on efficient digitization.

YouTube video by Steel Pulse - Topic

PİRHA-HBVAKV Avcılar Şubesi Yeşilkent Cemevi Başkanı Aslan Uzun’un, Colani hakkında suç duyurusunda bulunduğu için gözaltına alınıp tutuklanmasına tepki gösteren PSAKD Altınova Şube Başkanı Adnan Arsl...

YouTube video by Adam Mockler

YouTube video by Adam Mockler

YouTube video by Adam Mockler

CLASSIC MOVIE REVIEW: Bette Davis and Joan Crawford, two of Hollywood's most iconic and openly admired stars by the gay community, have a field day and deliver the comeback performances of the century in Robert Aldrich’s horror classic WHATEVER HAPPENED TO BABY JANE? (’62). The two stars are both incredible as sisters who carry too many secrets and whose relationship deteriorates into madness and murder. With solid support from Oscar nominee Victor Buono, Marjorie Bennett, and wonderful Maidie Norman as the caretaker who knows too much, it’s an unforgettable tale of suspense that will have you riveted from beginning to end. "Tired Old Queen at the Movies," where old Hollywood lives on. WHATEVER HAPPENED TO BABY JANE? (Anniversary Edition) DVD https://amzn.to/4b9ureN Stream WHATEVER HAPPENED TO BABY JANE? https://amzn.to/4c6YJjF WHATEVER HAPPENED TO BABY JANE? 27 x 40 Movie Poster - Style D https://amzn.to/4bbLpJx PRIDE Merch: Rainbow Sunflower LGBT Gay Pride Boots https://amzn.to/4eqYPEh Pride Flag Sport Shoes for Men Women Non Slip Lightweight Breathable Walking Running Shoes https://amzn.to/4c8ZM2s Pride Shirt Short Sleeve https://amzn.to/3xoeJOX FUNKO POP • Bette Davis as Baby Jane Hudson https://amzn.to/3NDo7TR • Joan Crawford as Blanche Hudson https://amzn.to/3TBhDZr • Funko Pop! Movies: Film Directors Alfred Hitchcock https://amzn.to/3VdCXBR • Funko Pop! Movies: The Godfather 50th - Vito https://amzn.to/3Av2eQ0 • Funko Pop! Movies: E.T. The Extra-Terrestrial - Elliot with E.T. in Basket https://amzn.to/3VbIU2c • Funko Pop! Movies: Rocky 45th Anniversary - Rocky Balboa https://amzn.to/3Av9c7C • Funko Pop! Movies: Marilyn Monroe (7 Year Itch) https://amzn.to/3XyDYGP • Funko Pop! Movies: Marilyn Monroe B&W https://amzn.to/3i2YzTd • Funko Pop! Movies: Pan’s Labyrinth - Jareth (David Bowie) https://amzn.to/3XgrZgV • Funko Pop! Movies: Elf The Movie - Buddy The Elf https://amzn.to/3hYZXGn • Funko Pop! Movies: Film Directors John Waters https://amzn.to/3ErBkJZ • Funko Pop! Movies: Dirty Dancing Finale https://amzn.to/3gterOf • Funko Pop! Movies: Jaws - Chief Brody https://amzn.to/3VdGgsL • Funko Pop! Movies: Psycho - Norman Bates https://amzn.to/3OtI9zw The Bette Davis Collection, Vol. 1 (Now, Voyager / Dark Victory / The Letter / Mr. Skeffington / The Star) https://amzn.to/2ySYvz9 Bette Davis Centenary Celebration Collection DVD (All About Eve / Hush...Hush, Sweet Charlotte / The Virgin Queen / Phone Call from a Stranger / The Nanny) https://amzn.to/362aR4l The Joan Crawford DVD Collection (Humoresque / Possessed (1947) / The Damned Don't Cry / The Women / Mildred Pierce) https://amzn.to/3LbzOOi Books: "Bette Davis : Larger Than Life" by Richard Schickel https://amzn.to/3XwFBHc "This 'N That" by Bette Davis https://amzn.to/2WpdlGH "The Lonely Life: An Autobiography " by Bette Davis https://amzn.to/3dwR13m "Mother Goddam : Bette Davis" by Whitney Stine and Bette Davis https://amzn.to/2xUhZCZ A TRUE STORY MOMMIE DEAREST by Christina Crawford https://amzn.to/46r145A “Possessed: The Life of Joan Crawford” by Donald Spoto https://amzn.to/3OBeILy “My Way of Life” Hardcover by Joan Crawford https://amzn.to/3xSCg8x Stream MOMMIE DEAREST https://amzn.to/45fBlfk Favorite T-Shirts: WHATEVER HAPPENED TO BABY JANE? Classic T-Shirt https://amzn.to/3Vvhzdd Bette Davis Glam T-Shirt https://amzn.to/45vJz4O Andy Warhol Pop Portraits Classic WHATEVER HAPPENED TO BABY JANE? T-Shirt https://amzn.to/3VOJTsr "I Speak Fluent Movie Quotes" | T-Shirt https://amzn.to/2LNv0l0 Mel Odom’s Gene Doll: https://amzn.to/3YamXmE Joan Crawford Magnetic Poster “Silver Screen” Cover FRIDGE MAGNET various sizes https://amzn.to/37EcIBA "Old age is no place for sissies." - Bette Davis quotes fridge magnet, Black https://amzn.to/2TeYsVw "I'd luv to kiss ya, but I just washed my hair." - Bette Davis quotes fridge magnet, White https://amzn.to/2zHb80h "As an Amazon Associate I earn from qualifying purchases.” Follow STEVE HAYES: Tired Old Queen at the Movies On: TikTok - https://www.tiktok.com/@stevehayestoq Twitter - https://twitter.com/SteveHayesTOQ

Radical SAM enzymes are the most widespread biocatalysts. These metalloenzymes, using S-adenosyl-l-methionine (SAM) and a [4Fe-4S] cluster as central cofactors, catalyze a broad range of chemically challenging transformations. The vast majority of radical SAM enzymes initiate their reaction by the homolytic cleavage of the SAM C5′–S bond and the generation of the central 5′-deoxyadenosyl radical (5′-dA·). In this study, by combining spectroscopic approaches with labeling and biochemical analyses, we show that ArsL, the key enzyme in the biosynthesis of the arsenic-containing antibiotic arsinothricin, catalyzes a unique reaction: the addition of the 3-amino-3-carboxypropyl radical (ACP·) to As(III). Remarkably, by exploiting several radical trapping strategies, we demonstrate that in sharp contrast to canonical radical SAM enzymes ArsL cleaves the SAM Cγ-S bond. In addition, using electron paramagnetic resonance (EPR) and hyperfine sublevel correlation (HYSCORE) spectroscopies, we establish that ArsL has a unique SAM binding mode, consistent with its catalytic properties and predicted structure. Notably, EPR and HYSCORE analyses support that SAM interacts with the radical SAM [4Fe-4S] cluster in an uncharacteristic conformation to form ACP·. Collectively, our study reveals that members of the superfamily of radical SAM enzymes are able to finely tune the binding of the SAM cofactor in order to perform unique chemistries.